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Additional file 1: Table 1. Genotype frequencies and univariate logistic regression of SNP with CMV infection status.

Additional file 2. Table 1: HIV-infected non-transmitting participants. Comparison of characteristics of HIV-infected non-transmitting participants between the study sample and the control sample. Data are expressed as n (%) or median (IQR); min-max unless stated otherwise. P-values to compare patient groups were calculated using the Mann-Whitney U test or Fisher’s exact test where appropriate. Missing data are indicated in the following manner: number of * = number of missing data points. Abbreviations: BMI: body mass index, CMV: cytomegalovirus, HIV: human immunodeficiency virus, WHO: world health organisation, N/A: not applicable. Table 2: HIV-uninfected participants. Comparison of characteristics of HIV-uninfected mothers between the study sample and the control sample. Data are expressed as n (%) or median (IQR); min-max unless stated otherwise. P-values to compare groups were calculated using Mann-Whitney U test or Fisher’s exact test where appropriate. Missing data are indicated in the following manner: number of * = number of missing data points. Abbreviations: BMI: body mass index, CMV: cytomegalovirus, HIV: human immunodeficiency virus, WHO: world health organisation, N/A: not applicable. Table 3: HIV-infected and uninfected study participants. Sample characteristics stratified for HIV status and CMV-DNAemia (4). Data are expressed as n (%) or median (IQR); min-max unless stated otherwise. P-values to compare patient groups were calculated using the Kruskal Wallis test, Mann-Whitney U test or Fisher’s exact test where appropriate. Missing data are indicated in the following manner: number of * = number of missing data points. Abbreviations: BMI: body mass index, CMV: cytomegalovirus, HIV: human immunodeficiency virus, WHO: world health organisation, N/A: not applicable. Table 4: CMV viremic and aviremic participants. Sample characteristics stratified for HIV status, cART exposure and CMV status and analysis of differences in participant groups. Data are expressed as n (%) or median (IQR); min-max unless stated otherwise. For calculation of vertical transmissions only infants that survived the first 6 weeks were included; exclusions due to death are marked with one “†” for each deceased infant. P-values to compare patient groups were calculated using the Kruskal Wallis test, Mann-Whitney U test or Fisher’s exact test where appropriate. Missing data are indicated in the following manner: number of * = number of missing data points. Abbreviations: BMI: body mass index, CMV: cytomegalovirus, cART: combination antiretroviral treatment, HIV: human immunodeficiency virus, WHO: world health organisation, N/A: not applicable. Table 5: Predictors of maternal CMV-DNA load. Linear regression showing the association of different variables with maternal CMV-DNA load in HIV-infected non-transmitting mothers after the removal of 0 outliers by the Tukey's fences method (Q1 – 3×IQR and Q3 + 3×IQR). Results are presented as linear coefficients; p-values are indicated as follows: *: p

Additional file 2. Table 1: HIV-infected non-transmitting participants. Comparison of characteristics of HIV-infected non-transmitting participants between the study sample and the control sample. Data are expressed as n (%) or median (IQR); min-max unless stated otherwise. P-values to compare patient groups were calculated using the Mann-Whitney U test or Fisher’s exact test where appropriate. Missing data are indicated in the following manner: number of * = number of missing data points. Abbreviations: BMI: body mass index, CMV: cytomegalovirus, HIV: human immunodeficiency virus, WHO: world health organisation, N/A: not applicable. Table 2: HIV-uninfected participants. Comparison of characteristics of HIV-uninfected mothers between the study sample and the control sample. Data are expressed as n (%) or median (IQR); min-max unless stated otherwise. P-values to compare groups were calculated using Mann-Whitney U test or Fisher’s exact test where appropriate. Missing data are indicated in the following manner: number of * = number of missing data points. Abbreviations: BMI: body mass index, CMV: cytomegalovirus, HIV: human immunodeficiency virus, WHO: world health organisation, N/A: not applicable. Table 3: HIV-infected and uninfected study participants. Sample characteristics stratified for HIV status and CMV-DNAemia (4). Data are expressed as n (%) or median (IQR); min-max unless stated otherwise. P-values to compare patient groups were calculated using the Kruskal Wallis test, Mann-Whitney U test or Fisher’s exact test where appropriate. Missing data are indicated in the following manner: number of * = number of missing data points. Abbreviations: BMI: body mass index, CMV: cytomegalovirus, HIV: human immunodeficiency virus, WHO: world health organisation, N/A: not applicable. Table 4: CMV viremic and aviremic participants. Sample characteristics stratified for HIV status, cART exposure and CMV status and analysis of differences in participant groups. Data are expressed as n (%) or median (IQR); min-max unless stated otherwise. For calculation of vertical transmissions only infants that survived the first 6 weeks were included; exclusions due to death are marked with one “†” for each deceased infant. P-values to compare patient groups were calculated using the Kruskal Wallis test, Mann-Whitney U test or Fisher’s exact test where appropriate. Missing data are indicated in the following manner: number of * = number of missing data points. Abbreviations: BMI: body mass index, CMV: cytomegalovirus, cART: combination antiretroviral treatment, HIV: human immunodeficiency virus, WHO: world health organisation, N/A: not applicable. Table 5: Predictors of maternal CMV-DNA load. Linear regression showing the association of different variables with maternal CMV-DNA load in HIV-infected non-transmitting mothers after the removal of 0 outliers by the Tukey's fences method (Q1 – 3×IQR and Q3 + 3×IQR). Results are presented as linear coefficients; p-values are indicated as follows: *: p