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Additional file 14: Figure S6. Principal component analysis of 88 normal samples from GTEx dataset and 499 tumor samples from TCGA RNA sequencing-based dataset, using all the target genes negatively correlated to the 9 miRNA signature and significantly modulated between normal samples and tumor samples.

Additional file 12: Figure S4. Kaplan-Meier curves relative to the 5 miRNAs of the TCGA prognostic signature, showing their impact on EFS. Statistical significance was established by logrank test. For all the comparisons, the level of statistical significance was p

Additional file 11: Figure S3. Kaplan-Meier curves relative to the 5 miRNAs of the TCGA prognostic signature, showing their impact on EFS. Statistical significance was established by logrank test. For all the comparisons, the level of statistical significance was p

Additional file 10: Figure S2. Kaplan-Meier curves illustrating the performance of the IRE prognostic signature in the TCGA cohort for EFS (A), and OS (B). Kaplan-Meier curves showing the impact of miR-224-5p on EFS in the IRE cohort (C). Differences between curves were evaluated by logrank test. Box plots illustrating the expression level of miR-224-5p in tumor samples (T) versus normal tissue samples (N), in the TCGA cohort (D), and in the IRE cohort (E). Box plots showing the expression levels of miR-200a in platinum resistant tumors (resist) versus platinum sensitive tumors (resist), in the TCGA (F). Differences in miRNAs expression were assessed by Student’s T-test. For all the comparisons, the level of statistical significance was p