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Figure S1. UFC1 knockdown inhibits gastric cancer cell proliferation, migration and invasion. Figure S2. UFC1 overexpression enhances gastric cancer cell proliferation, migration and invasion. Figure S3. Bioinformatic prediction of UFC1-binding miRNAs and target genes of miR-498. Figure S4. Relative expression levels of miR-498 and Lin-28b in gastric cancer cells and gastric cancer tissues. Figure S5. UFC1 overexpression antagonizes miR-498-medited inhibition of gastric cancer cell proliferation, migration and invasion. Figure S6. Lin28b knockdown inhibits gastric cancer cell proliferation, migration and invasion. Figure S7. Lin28b overexpression promotes gastric cancer cell proliferation, migration and invasion. Figure S8. UFC1 promotes gastric cancer cell proliferation, migration and invasion via the upregulation of Lin28b. (DOCX 19 kb)

Table S1. The sequences of primers for qRT-PCR. Table S2 The sequences of control and UFC1 shRNAs. Table S3. The association between UFC1 expression levels (–ΔCt) in tumor tissues and the clinicopathological features of gastric cancer patients. Table S4. The correlation between serum UFC1 expression levels (–ΔCt) and the clinicopathological characteristics of gastric cancer patients. Table S5. The correlation between exosomal UFC1 expression levels (–ΔCt) and the clinicopathological parameters of gastric cancer patients. (DOCX 25 kb)