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Multivariate Coxâ s proportional hazards regression model each evidence-based medications. Abbreviations: CAD: coronary artery disease, CI: confidence interval, CV death: cardiovascular death, HR: hazard ratio, LDL-C: low-density lipoprotein-cholesterol, STEMI: ST-segment elevated myocardial infarction. Adjusted factor: sex, history of hypertension, history of diabetes mellitus, and history of heart failure, history of dyslipidemia, smoking status, eGFR and hepatic enzymes. (DOCX 13 kb)

Discharge prescription of ACEI/ARBs for CAD patients (panel A) and CAD patients without hypertension (panel B) stratified by age. Abbreviations: CAD, coronary artery disease; ACEI, angiotensin-converting enzyme inhibitor; ARBs, angiotensin receptor blockers. (DOCX 95 kb)

Number of matched pairs, before-matched and c-statistic. (DOCX 16 kb)

Multivariate Coxâ s proportional hazards regression model on combination therapy of EBMs. Adjusted factor: sex, history of hypertension, history of diabetes mellitus, and history of heart failure, history of dyslipidemia, smoking status, eGFR and hepatic enzymes. Model 0: no medication; model 1: prescribed 1 type of EBMs; model 2, prescribed 2 types of EBMs; model 3, prescribed all 3 types of EBMs. Three types of EBMs included: statin, beta-blockers, and RAAS inhibitors (ACEIs or ARBs). Abbreviations: EBMs: evidence-based medications, CAD: coronary artery disease, CI: confidence interval, CV death: cardiovascular death, HR: hazard ratio. (DOCX 13 kb)