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Additional file 1: Figure S1. Alignment of the conserved YKELRLRGY motif. Figure S2. Amino acid alignment of the pseudo-methyltransferase (ΨME) domain of H. sapiens and Ae. aegypti FAS. Figure S3. RT-PCR assays designed to detect mRNA products of AaFAS-like and AaFAS6. Table S1. List of vertebrate, invertebrate and yeast FAS gene models employed in the present study. Table S2. Primers for generation of dsRNA for knock-down studies. Table S3. Primers for AaFAS expression analyses. Table S4. Primers for RT-PCR assay detecting mRNA products AaFAS-like and AaFAS6. Table S5. Amino acid similarity of FAS domains between H. sapiens and Ae. aegypti. Table S6. Comparisons of percent infection in mosquitoes (P-values). Table S7. Virus titers in mosquito tissues.

Additional file 2: File S1. mRNA and amino acid sequences of 7 AaFAS genes.