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Additional file 1. Supplementary file and appendices

Additional file 2: Table S1. Baseline characteristics of post-myocardial infarction patients age 65 and older discharged home following a cardiac catheterization in Ontario, Canada from September 2015 to August 2018 – stratified by intervention group.

Additional file 3: Table S2. Results from patient-level segmented regression analyses estimating the relative immediate and gradual effects of study interventions on secondary medication-related outcomes among post-myocardial infarction patients age 65 and older in Ontario, Canada from September 2015 to August 2018.

Additional file 5: Table S4. Proportion of patients with a prolonged discharge prescription for ≥90 days with 3 repeats by cardiac medication class during the 12-month intervention period based on hospital chart data. Notes: a ≥ 90 days supplied on average across cardiac medication classes with a discharge prescription without consideration of number of repeats on prescription(s).

Additional file 1: Figure S1. Monthly proportion of post-myocardial infarction patients age 65 and older with initial average prescription duration (i.e., days supplied at index fill) ≥90 days for cardiac medications – stratified by intervention group – from September 2015 to August 2018 in Ontario, Canada. Notes: Observed values are denoted by x, solid lines represent the fitted regression pre- and post-intervention trendlines for a given group, and hatched lines represent the projected pre-intervention trend assuming there was no intervention in that group (i.e., the counterfactual).

Additional file 4: Table S3. Results from patient-level segmented regression analyses estimating the relative immediate and gradual effects of study interventions on secondary outcomes capturing health care utilization and clinical outcomes among post-myocardial infarction patients age 65 and older in Ontario, Canada from September 2015 to August 2018.

Table S3. Preoperative cardiac testing methodology summary. Tables describing methodological details and relevant codes used for preoperative cardiac testing study. (DOCX 17 kb)

Table S4. Screening mammography methodology summary. Tables describing methodological details and data handling procedure for screening mammography study. (DOCX 15 kb)

Table S1. Utilization of unnecessary services related to three Choosing Wisely Canada (CWC) recommendations. Table describing CWC recommendations for lower back pain imaging, preoperative cardiac testing, and screening mammography, and methodological details pertaining to each of the three studies. (DOCX 16 kb)

Comprehensive search strategy. Description: this file contains the search terms and strategy using in our comprehensive search. (DOCX 21 kb)

Included Studies. Description: this table contains the details of all published papers selected for study inclusion. (DOCX 42 kb)

Comprehensive search strategy. Description: this file contains the search terms and strategy using in our comprehensive search. (DOCX 21 kb)

Included Studies. Description: this table contains the details of all published papers selected for study inclusion. (DOCX 42 kb)