1. In vitro effect of experimental nanocomposites solutions on the prevention of dental caries around orthodontic brackets
- Author
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Ricardo Tadeu Lopes, Thiago Isidro Vieira, Raphael Ferreira da Silva, Lucio Mendes Cabral, Yuri Wanderley Cavalcanti, Aline de Almeida Neves, Aline Saddock de Sá Silva, Matheus Melo Pithon, Lucianne Cople Maia, Karla Lorene de França Leite, Adílis Kalina Alexandria, and Andréa Fonseca-Gonçalves
- Subjects
Orthodontic Brackets ,chemistry.chemical_element ,Dental Caries ,Nanocomposites ,Fluorides ,chemistry.chemical_compound ,Sodium fluoride ,Nanotechnology ,Humans ,Dental Enamel ,Tooth Demineralization ,General Dentistry ,Titanium ,Polarized light microscopy ,Nanocomposite ,Enamel paint ,Dental Biofilm ,Mesoporous silica ,Cariostatic Agents ,chemistry ,visual_art ,visual_art.visual_art_medium ,Titanium tetrafluoride ,Sodium Fluoride ,Fluoride ,Nuclear chemistry - Abstract
This study aimed to evaluate the in vitro effect of a single application of experimental nanocomposite solutions on the prevention of dental caries around orthodontic brackets. The specimens were exposed to mesoporous silica (MS) nanocomposites containing fluoride by association with titanium tetrafluoride (TiF4) or sodium fluoride (NaF). Nanocomposites also could contain calcium and groups were described as MSCaTiF4, MSTiF4, MSCaNaF, MSNaF, and controls (TiF4, and NaF). Specimens were subjected to the formation of a multispecies biofilm to generate a cariogenic challenge. After 24h, both pH and total soluble fluoride concentration of the culture medium were assessed. Mineral loss was evaluated by percentage of surface mineral loss (%SML), mineral volume variation (ΔZ) of inner enamel and polarized light microscopy (PL). Linear (Ra) and volumetric (Sa) surface roughness and scanning electronic microscopy (SEM) were used to assess enamel topography. Statistical analyses were conducted considering p
- Published
- 2021
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