1. A new diagnostic marker for acute pulmonary embolism in emergency department: mean platelet volume.
- Author
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Talay F, Ocak T, Alcelik A, Erkuran K, Akkaya A, Duran A, Demirhan A, Kar Kurt O, and Asuk Z
- Subjects
- Acute Disease, Adult, Aged, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Pulmonary Embolism blood, ROC Curve, Retrospective Studies, Risk Factors, Young Adult, Biomarkers blood, Blood Platelets pathology, Emergency Medical Services methods, Mean Platelet Volume methods, Mean Platelet Volume statistics & numerical data, Pulmonary Embolism diagnosis
- Abstract
Objective: To investigate the diagnostic importance of mean platelet volume (MPV) on acute pulmonary embolism (APE) in the emergency Department (ED)., Methods: Subjects were selected from patients admitted to ED with clinically suspected APE. Demographic, anthropometric and serologic data were collected for each patient., Results: A total of 315 consecutive patients were analyzed, including 150 patients (53.44 ± 15.14 y; 92 men/58 women) in APE group and 165 patients (49.80 ±13.76y; 94 men/71 women) in the control group. MPV in the APE group was significantly higher than in the control group (9.42±1.22 fl vs. 8.04±0.89 fl, p<0.0001). The best cut-off values for MPV when predicting APE in patients with clinically suspected APE presenting at the ED were 8.55 fl (sensitivity 82.2%; specificity 52.3%)., Conclusions: MPV is a helpful parameter for the diagnosis of APE in ED, for the first time in the literature.
- Published
- 2014
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