1. Recent advances in the understanding of immune-mediated nephrotic syndrome: diagnostic and prognostic implications
- Author
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Sjoerd A.M.E.G. Timmermans, Pieter van Paassen, Jan Willem Cohen Tervaert, Promovendi CD, MUMC+: MA Nefrologie (9), MUMC+: MA Klinische Immunologie (9), Interne Geneeskunde, RS: CARIM - R1 - Thrombosis and haemostasis, and RS: MHeNs - R1 - Cognitive Neuropsychiatry and Clinical Neuroscience more...
- Subjects
medicine.medical_specialty ,Pathology ,Biopsy ,membranoproliferative glomerulonephritis ,Immunology ,Amyloid Neuropathies ,Kidney ,urologic and male genital diseases ,Nephropathy ,Glomerulonephritis ,Focal segmental glomerulosclerosis ,Membranous nephropathy ,prognostics ,Internal medicine ,Membranoproliferative glomerulonephritis ,medicine ,diagnostics ,Animals ,Humans ,Immunology and Allergy ,Minimal change disease ,amyloidosis ,focal segmental glomerulosclerosis ,medicine.diagnostic_test ,business.industry ,nephrotic syndrome ,Amyloidosis ,membranous nephropathy ,IgA nephropathy ,Prognosis ,medicine.disease ,Proteinuria ,Endocrinology ,minimal change disease ,Renal biopsy ,business ,Nephrotic syndrome ,Glomerular Filtration Rate - Abstract
Glomerular diseases with severe defects in glomerular permeability give rise to heavy proteinuria and can present as nephrotic syndrome. There are many different causes of the nephrotic syndrome and a renal biopsy is nearly always needed to elucidate the underlying disease. During the last decade, substantial advances have occurred in the understanding of the pathophysiological mechanisms involved in immune-mediated glomerular diseases. Here, we review the diagnostic and prognostic implications of recent progress on the understanding of membranous nephropathy, minimal change disease, focal segmental glomerulosclerosis, amyloidosis, IgA nephropathy and membranoproliferative glomerulonephritis. more...
- Published
- 2015