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1. THE EUROPEAN SLEEP APNOEA DATABASE (ESADA) -- Report from 22 European Sleep Laboratories

Author

Jan Hedner, A. Vitols, M. Pretl, Pawel Sliwinski, Ingo Fietze, John-Arthur Kvamme, Daniel Rodenstein, Ruzena Tkacova, Juan F. Masa, Marisa Bonsignore, Thomas Penzel, Ludger Grote, Ferran Barbé, J.M. Montserrat, Renata L. Riha, Rainer Schulz, Jan Zieliński, Walter Mcnicholas Mcnicholas, W DeBacker, Pierre Escourrou, Tarja Saaresranta, Marrone O, H. Vrints, Peretz Lavie, Giedrius Varoneckas, Carolina Lombardi, Gianfranco Parati, Hedner, J, Grote, L, Bonsignore, MR, McNicholas, W, Lavie, P, Parati, G, Sliwinski, P, Barbé, F, Escourrou, P, Fietze, I, Masa, JF, Kvamme, JA, Lombardi, C, Marrone, O, Montserrat, JM, Penzel, T, Pretl, M, Riha, R, Rodenstein, D, Saaresranta, T, Schulz, R, Tkacova, R, Varoneckas, G, Vitols, A, Vrints, H, Zielinski, J, UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, UCL - (SLuc) Service de pneumologie, Bonsignore, M, Mcnicholas, W, Masa, J, Kvamme, J, Montserrat, J, and Debacker, W

Subjects
Pulmonary and Respiratory Medicine, Adult, Male, Pediatrics, medicine.medical_specialty, Adolescent, Databases, Factual, Cross-sectional study, Polysomnography, Comorbidity, Cohort Studies, Sleep Apnea Syndromes, Risk Factors, Surveys and Questionnaires, medicine, Humans, Medical history, Respiratory system, Aged, Sleep disorder, medicine.diagnostic_test, Anthropometry, Models, Genetic, business.industry, comorbidity, European Sleep Apnoea Database, genetic, multicentre cohort, obstructive sleep apnoea syndrome, Cardiorespiratory fitness, MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE, Middle Aged, medicine.disease, respiratory tract diseases, Obesity, Morbid, Europe, Cohort, Female, Human medicine, business
Abstract

The European Sleep Apnoea Database (ESADA) reflects a network of 22 sleep disorder centres in Europe enabled by a COST action B26 programme. This ongoing project aims to describe differences in standard clinical care of patients with obstructive sleep apnoea (OSA) and to establish a resource for genetic research in this disorder. Patients with suspected OSA are consecutively included and followed up according to local clinical standards. Anthropometrics, medical history, medication, daytime symptoms and sleep data (polysomnography or cardiorespiratory polygraphy) are recorded in a structured web-based report form. 5,103 patients (1,426 females, mean±SD age 51.8±12.6 yrs, 79.4% with apnoea/hypopnoea index (AHI) ≥5 events·h -1) were included from March 15, 2007 to August 1, 2009. Morbid obesity (body mass index ≥35 kg·m -2) was present in 21.1% of males and 28.6% of females. Cardiovascular, metabolic and pulmonary comorbidities were frequent (49.1%, 32.9% and 14.2%, respectively). Patients investigated with a polygraphic method had a lower AHI than those undergoing polysomnography (23.2±23.5 versus 29.1±26.3 events·h -1, p

Published
2011

2. The European Sleep Apnoea Database (ESADA): report from 22 European sleep laboratories.

Author

Hedner J, Grote L, Bonsignore M, McNicholas W, Lavie P, Parati G, Sliwinski P, Barbé F, De Backer W, Escourrou P, Fietze I, Kvamme JA, Lombardi C, Marrone O, Masa JF, Montserrat JM, Penzel T, Pretl M, Riha R, Rodenstein D, Saaresranta T, Schulz R, Tkacova R, Varoneckas G, Vitols A, Vrints H, and Zielinski J

Subjects
Adolescent, Adult, Aged, Anthropometry methods, Cohort Studies, Comorbidity, Databases, Factual, Europe, Female, Humans, Male, Middle Aged, Models, Genetic, Obesity, Morbid complications, Risk Factors, Sleep Apnea Syndromes physiopathology, Surveys and Questionnaires, Sleep Apnea Syndromes diagnosis, Sleep Apnea Syndromes epidemiology
Abstract

The European Sleep Apnoea Database (ESADA) reflects a network of 22 sleep disorder centres in Europe enabled by a COST action B26 programme. This ongoing project aims to describe differences in standard clinical care of patients with obstructive sleep apnoea (OSA) and to establish a resource for genetic research in this disorder. Patients with suspected OSA are consecutively included and followed up according to local clinical standards. Anthropometrics, medical history, medication, daytime symptoms and sleep data (polysomnography or cardiorespiratory polygraphy) are recorded in a structured web-based report form. 5,103 patients (1,426 females, mean±sd age 51.8±12.6 yrs, 79.4% with apnoea/hypopnoea index (AHI) ≥5 events·h(-1)) were included from March 15, 2007 to August 1, 2009. Morbid obesity (body mass index ≥35 kg·m(-2)) was present in 21.1% of males and 28.6% of females. Cardiovascular, metabolic and pulmonary comorbidities were frequent (49.1%, 32.9% and 14.2%, respectively). Patients investigated with a polygraphic method had a lower AHI than those undergoing polysomnography (23.2±23.5 versus 29.1±26.3 events·h(-1), p<0.0001). The ESADA is a rapidly growing multicentre patient cohort that enables unique outcome research opportunities and genotyping. The first cross-sectional analysis reveals a high prevalence of cardiovascular and metabolic morbidity in patients investigated for OSA.

Published
2011
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