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Ozet : Gonadotropin serbestlestirici hormon (GnRH) agonisti ile oosit maturasyonunun tetiklendigi ve sonrasinda tum embriyolarin donduruldugu 27 yasindaki olguda luteal destek olmaksizin olusan spontan klinik gebelik sunulmustur. Polikistik over sendromu (PKOS) tanisiyla, oncesinde 3 sefer kontrollu ovaryan stimulasyon ve intrauterin inseminasyon uygulanmis olan hastaya GnRH antagonist protokolu ile intrasitoplasmik sperm enjeksiyonu tedavisi planlandi. Stimulasyonun 11. gununde ≥11 mm 25 adet folikul saptanmasi uzerine GnRH agonisti uygulanarak final oosit maturasyonu saglandi. Blastokist evresine kadar gelisim gosteren yuksek kalitedeki embriyolarin tumu vitrifiye edildi. Taze embriyo transferi planlanmamasi dolayisiyla hastaya luteal faz destegi verilmeyerek yedi gun sureyle cinsel iliski onerilmedi. Ancak, oosit toplanmasinin 5 hafta sonrasinda amenore yakinmasiyla tarafimiza tekrar basvuran hastaya yapilan transvajinal ultrasonografide fetal kalp atimi muspet spontan tekiz gebelik izlendi. Gunumuzde, GnRH agonistlerle tetikleme sonrasi luteal fazin nasil desteklenmesi gerektigine dair yogun tartismalar devam etmektedir. Bu bulgular, ovaryan stimulasyon sonrasi suprafizyolojik steroid seviyelerine ragmen, her hastanin korpus luteum fonksiyonlarinin devaminin farklilik gosterebilecegine isaret etmektedir. Dolayisiyla, PKOS ve beraberinde endojen luteinizan hormon aktivitesinin yuksek oldugu hastalar, korpus luteumun sinirli ancak luteal faz icin yeterli aktivitesinin devam edebilecegi bir alt grubu olusturuyor olabilir. Anahtar kelimeler: GnRH agonist tetikleme, luteal faz destegi, spontan gebelik SPONTANEOUS CLINICAL PREGNANCY FOLLOWING GNRH AGONIST TRIGGERING AND FREEZE ALL POLICY Abstract: We describe a 27 year-old patient undergoing follicle stimulation with gonadotrophin releasing hormone (GnRH) agonist and freeze-all approach, presented with spontaneous clinical pregnancy without supplementation of luteal phase. The patient had three attempts with controlled ovarian hyperstimulation and intrauterine insemination due to polycystic ovary syndrome (PCOS) before referring to our clinic for intracytoplasmic sperm injection. A GnRH antagonist protocol was assigned and ovarian stimulation commenced. After the detection of 25 follicles ≥11 mm, final oocyte maturation was triggered with GnRH agonist on the eleventh day of stimulation. Since freeze all approach was taken, no luteal phase support was administered. High quality blastocysts were vitrified. The couple was advised to refrain from sexual intercourse for seven days. The patient, however, presented with amenorrhea five weeks after the day of oocyte retrieval. A clinical pregnancy with fetal cardiac activity was determined on ultrasound examination. Currently, there is an ongoing debate on how best to counteract the negative impact of agonist triggering on the luteal phase. Our case demonstrates that corpus luteum functions might diverse despite supra-physiological sex steroids resulting from ovarian stimulation. Therefore, in case of PCOS consisting high endogenous LH activity, corpus luteum might be rescued and luteolysis might limit itself in such cycles shortly after implantation. Keywords: GnRH agonist trigger, luteal phase support, spontaneous conception