1. [Evaluation of fetomaternal hemorrhage in postpartum patients with indication for administration of anti-D immunoglobulin].
- Author
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Baiochi E, Camano L, and Bordin JO
- Subjects
- Adult, Female, Fetomaternal Transfusion therapy, Humans, Postpartum Period, Pregnancy, Rho(D) Immune Globulin therapeutic use, Triage economics, Blood Volume, Fetomaternal Transfusion physiopathology, Rh Isoimmunization prevention & control, Rho(D) Immune Globulin administration & dosage, Triage methods
- Abstract
This study evaluated fetomaternal hemorrhage (FMH) in 343 postpartum patients who required prophylaxis of Rh alloimmunization with anti-D immunoglobulin. The rosette test was applied to screen for patients needing quantitative determination of fetal blood transferred from the maternal circulation, which was then measured by the Kleihauer-Betke test (K-B). The rosette test was positive in 22 cases (6.4%). In five of these cases, K-B did not show fetomaternal hemorrhage (a 1.45% false-positive rate for the rosette test), and in one case the test was inconclusive. There were 8 cases with FMH < 10 ml (2.3%), 6 cases with FMH from 10 to 30 ml (1.7%), and two cases with FMH > 30 ml (0.58%), requiring a supplementary dose of anti-D. The study concludes that following the rosette test, additional evaluation of FMH using a quantitative test was unnecessary in 93.6% of the cases.
- Published
- 2005
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