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Your search keyword '"Ratlhagana, Mary J."' showing total 2 results
Start Over Author "Ratlhagana, Mary J." Publisher escholarship, university of california
2 results on '"Ratlhagana, Mary J."'

1. Impact of short message service and peer navigation on linkage to care and antiretroviral therapy initiation in South Africa

Author

Lippman, Sheri A, de Kadt, Julia, Ratlhagana, Mary J, Agnew, Emily, Gilmore, Hailey, Sumitani, Jeri, Grignon, Jessica, Gutin, Sarah A, Shade, Starley B, Gilvydis, Jennifer M, Tumbo, John, Barnhart, Scott, and Steward, Wayne T

Subjects
Biomedical and Clinical Sciences, Public Health, Health Sciences, Prevention, Pediatric, Clinical Research, Clinical Trials and Supportive Activities, HIV/AIDS, Health Services, Mental Health, Evaluation of treatments and therapeutic interventions, 6.1 Pharmaceuticals, Infection, Male, Adult, Female, Humans, Pregnancy, HIV Infections, Anti-HIV Agents, Text Messaging, South Africa, Cluster Analysis, antiretroviral therapy initiation, cluster randomized trial, HIV, linkage to care, peer navigation, short message service, Biological Sciences, Medical and Health Sciences, Psychology and Cognitive Sciences, Virology, Biomedical and clinical sciences, Health sciences
Abstract

ObjectiveWe examine the efficacy of short message service (SMS) and SMS with peer navigation (SMS + PN) in improving linkage to HIV care and initiation of antiretroviral therapy (ART).DesignI-Care was a cluster randomized trial conducted in primary care facilities in North West Province, South Africa. The primary study outcome was retention in HIV care; this analysis includes secondary outcomes: linkage to care and ART initiation.MethodsEighteen primary care clinics were randomized to automated SMS ( n  = 7), automated and tailored SMS + PN ( n  = 7), or standard of care (SOC; n  = 4). Recently HIV diagnosed adults ( n  = 752) were recruited from October 2014 to April 2015. Those not previously linked to care ( n  = 352) contributed data to this analysis. Data extracted from clinical records were used to assess the days that elapsed between diagnosis and linkage to care and ART initiation. Cox proportional hazards models and generalized estimating equations were employed to compare outcomes between trial arms, overall and stratified by sex and pregnancy status.ResultsOverall, SMS ( n  = 132) and SMS + PN ( n  = 133) participants linked at 1.28 [95% confidence interval (CI): 1.01-1.61] and 1.60 (95% CI: 1.29-1.99) times the rate of SOC participants ( n  = 87), respectively. SMS + PN significantly improved time to ART initiation among non-pregnant women (hazards ratio: 1.68; 95% CI: 1.25-2.25) and men (hazards ratio: 1.83; 95% CI: 1.03-3.26) as compared with SOC.ConclusionResults suggest SMS and peer navigation services significantly reduce time to linkage to HIV care in sub-Saharan Africa and that SMS + PN reduced time to ART initiation among men and non-pregnant women. Both should be considered candidates for integration into national programs.Trial registrationNCT02417233, registered 12 December 2014; closed to accrual 17 April 2015.

Published
2023

2. Improvements in the South African HIV care cascade: findings on 90‐90‐90 targets from successive population‐representative surveys in North West Province

Author

Lippman, Sheri A, Ayadi, Alison M El, Grignon, Jessica S, Puren, Adrian, Liegler, Teri, Venter, WD Francois, Ratlhagana, Mary J, Morris, Jessica L, Naidoo, Evasen, Agnew, Emily, Barnhart, Scott, and Shade, Starley B

Subjects
Biomedical and Clinical Sciences, Public Health, Health Sciences, Clinical Sciences, Infectious Diseases, Sexually Transmitted Infections, HIV/AIDS, Women's Health, Infection, Good Health and Well Being, Adolescent, Adult, Anti-HIV Agents, Continuity of Patient Care, Epidemics, Female, HIV, HIV Infections, Humans, Male, Mass Screening, Middle Aged, South Africa, Young Adult, care cascade, 90-90-90 targets, HIV care continuum, linkage to care, viral suppression, testing, Public Health and Health Services, Other Medical and Health Sciences, Clinical sciences, Epidemiology, Public health
Abstract

IntroductionTo achieve epidemic control of HIV by 2030, countries aim to meet 90-90-90 targets to increase knowledge of HIV-positive status, initiation of antiretroviral therapy (ART) and viral suppression by 2020. We assessed the progress towards these targets from 2014 to 2016 in South Africa as expanded treatment policies were introduced using population-representative surveys.MethodsData were collected in January to March 2014 and August to November 2016 in Dr. Ruth Segomotsi Mompati District, North West Province. Each multi-stage cluster sample included 46 enumeration areas (EA), a target of 36 dwelling units (DU) per EA, and a single resident aged 18 to 49 per DU. Data collection included behavioural surveys, rapid HIV antibody testing and dried blood spot collection. We used weighted general linear regression to evaluate differences in the HIV care continuum over time.ResultsOverall, 1044 and 971 participants enrolled in 2014 and 2016 respectively with approximately 77% undergoing HIV testing. Despite increases in reported testing, known status among people living with HIV (PLHIV) remained similar at 68.7% (95% Confidence Interval (CI) = 60.9-75.6) in 2014 and 72.8% (95% CI = 63.6-80.4) in 2016. Men were consistently less likely than women to know their status. Among those with known status, PLHIV on ART increased significantly from 80.9% (95% CI = 71.9-87.4) to 91.5% (95% CI = 84.4-95.5). Viral suppression (

Published
2019

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