1. MON-571 The Performance Of An Advanced Ultrasound Technique, Quantitative Ultrasound, Compared To Conventional Ultrasound In The Evaluation Of Thyroid Nodules
- Author
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Jonathan Mamou, Daniel Rohrbach, Sira Korpaisarn, Kirk D. Wallace, Stephanie L. Lee, Poorani Goundan, Ernest J. Feleppa, Jason T. Smith, and Harshal Patel
- Subjects
Quantitative ultrasound ,Thyroid nodules ,Thyroid ,business.industry ,Endocrinology, Diabetes and Metabolism ,Ultrasound ,Medicine ,business ,Nuclear medicine ,medicine.disease ,Conventional ultrasound ,Thyroid and Thyroid Nodule Imaging and Cancer Risk Stratification - Abstract
INTRODUCTION: Thyroid cancer is the most common endocrine malignancy. While thyroid nodules (TN) can been seen in up to 50% of the adult population, only about 5 percent of the nodules are malignant. Currently, management of TN involves risk stratification prior to biopsy using B-mode grey-scale ultrasound (US) characteristics including echogenicity, micro- and macrocalcifications, and margins. A less-subjective method of TN evaluation, shear wave elastography, has been evaluated but both the grey-scale classification and elastography are subject to operator and machine variability. This study assesses the use of quantitative ultrasound (QUS) to differentiate between malignant and benign thyroid nodules. B-mode appearance based on the radiofrequency (RF) signal envelope and discards much of the information in the RF signal. QUS uses the normalized power spectrum and extracts discarded RF signal information to obtain parameters that reflect scatterer size, concentration and relative acoustic impedance. The advantage of using QUS is that the parameter values reflect the microarchitecture (
- Published
- 2019