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Your search keyword '"Wagerle T"' showing total 2 results
Start Over Author "Wagerle T" Publisher elsevier science ltd
2 results on '"Wagerle T"'

1. Insecticidal quinoline and isoquinoline isoxazolines.

Author

Xu M, Wagerle T, Long JK, Lahm GP, Barry JD, and Smith RM

Subjects
Animals, Dose-Response Relationship, Drug, Insecticides chemical synthesis, Insecticides chemistry, Isoquinolines chemistry, Isoxazoles chemical synthesis, Isoxazoles chemistry, Molecular Structure, Quinolines chemistry, Hemiptera drug effects, Insecticides pharmacology, Isoxazoles pharmacology, Moths drug effects, Thysanoptera drug effects
Abstract

A series of quinoline and isoquinoline isoxazolines have been designed as pesticides for crop protection. Herein we reported the chemical synthesis, biological activity and structure-activity relationships. The isoquinoline derivative, such as 3i, is discovered as potent new class of isoxazoline insecticide which is competitive with commercial insecticide Indoxacarb., (Copyright © 2014 Elsevier Ltd. All rights reserved.)

Published
2014
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2. 4-Azolylphenyl isoxazoline insecticides acting at the GABA gated chloride channel.

Author

Lahm GP, Cordova D, Barry JD, Pahutski TF, Smith BK, Long JK, Benner EA, Holyoke CW, Joraski K, Xu M, Schroeder ME, Wagerle T, Mahaffey MJ, Smith RM, and Tong MH

Subjects
Animals, Chloride Channels metabolism, Dose-Response Relationship, Drug, Insecta, Insecticides chemical synthesis, Insecticides chemistry, Isoxazoles chemical synthesis, Isoxazoles chemistry, Molecular Structure, Structure-Activity Relationship, Chloride Channels antagonists & inhibitors, Insecticides pharmacology, Isoxazoles pharmacology, Receptors, GABA metabolism
Abstract

Isoxazoline insecticides have been shown to be potent blockers of insect GABA receptors with excellent activity on a broad pest range, including Lepidoptera and Hemiptera. Herein we report on the synthesis, biological activity and mode-of-action for a class of 4-heterocyclic aryl isoxazoline insecticides., (Copyright © 2013 Elsevier Ltd. All rights reserved.)

Published
2013
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