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Enhancing the solar-physical conversion efficacy ability of the nanomaterials is an essential for real-time implementation. We report the enhanced solar-physical efficiency of the BiFeO 3 nanospheres via Gd 3+ doping and Au nanoparticles decoration. Initially, we have obtained the Bi 1-x Gd x FeO 3 nanospheres were attained via a simple solvothermal technique and then citrate reduction of Au was conducted. Obtained perovskite BiFeO systems were studied for the Gd 3+ doping, crystalline phase and elemental purity using the XRD and XPS techniques. Transmission electron microscope had revealed the ∼400 nm sized BiFeO 3 nanospheres. Optical absorption spectrum revealed the enhanced visible photon absorption occurring in BiFeO 3 for both Gd 3+ doping and Au decoration. The bandgap values of pristine, 1%, 3% and 5% Gd 3+ doped in BiFeO 3 are 2.2 eV, 2.19 eV, 2.17 eV and 2.12 eV, respectively. Conducted photoluminescence revealed the dual electron trapping occurring in BiFeO 3 via Gd 3+ ions and Au nanoparticles. LED light assisted 72% of piezo-photocatalytic degradation efficiency of Tetracycline is achieved with Bi 0 95 Fe 0 05 O 3 /Au, whereas the photo catalytic is only 65% and piezo catalytic efficiency is 58%. In recyclable studies the Bi 0.95 Gd 0.05 FeO 3 /Au had shown the consistent piezo-photocatalytic efficiency for 3 reaction cycles. Further, fabricated DSSC studies revealed that near 30 % enhanced solar photovoltaic efficiency for Bi 0 95 Fe 0 05 O 3 /Au (η = 6.5%) solar cells on par to the pristine BiFeO 3 (η = 5.02%)., Competing Interests: Declaration of competing interest We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant fiscal things for this work that could have influenced its outcome., (Copyright © 2023 Elsevier Ltd. All rights reserved.)

A series of amide derivatives of stilbene was synthesized and investigated for osteogenic activity. Out of sixteen, seven compounds viz19c, 19g, 19i, 24b, 25a, 25c and 26a showed significant osteoblast differentiation within 1 pM-1 µM concentrations. Amongst all, 26a was identified as most active molecule which presented effective mineralization of osteoblasts and expression of mRNA of osteogenic marker gene such as BMP-2, ALP, and Runx-2 at 1 pM. In estrogen-deficient balb/c mice, 26a showed significant osteogenic activity at 5 mg-kg -1 body weight dose. The protein expression study for estrogen receptors α and β (ER-α & ER-β) using mouse calvarial osteoblasts (MCOs) and molecular docking analyses showed preferential expression of ER-β by 26a indicating the possibility of ER-β mediated osteogenic activity of 26a., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2020 Elsevier Ltd. All rights reserved.)

Micronuclei frequency is a sensitive biomarker used to evaluate the genotoxicity induced by xenobiotics. Pioglitazone and glimepiride were associated with genotoxicity in experimental studies conducted in rats. Considering the lack of published reports on genotoxicity in T2DM patients using pioglitazone and glimepiride drugs in combination, current study aimed to assess whether the case and control groups significantly differ from each other in the frequency of micronuclei. Subjects comprise 127 T2DM patients (35-65 years old) under pioglitazone and glimepiride treatment for >5 years and control group of 140 age matched healthy controls (38-69 years old). Exfoliated oral mucosa cells were collected from buccal mucosa of all subjects and Feulgen/Fast-Green method was followed to screen for micronuclei. Factors such as gender, food habits, living areas and occupation have not shown significant association with the variation in micronuclei frequency among the studied subjects. However, T2DM patients under long term treatment of pioglitazone and glimepiride in combination, showed increased frequency of micronuclei as compared to controls (p<0.001). Current study suggests that the micronuclei assay can be used as a constituent among the panel of biomarkers to assess genotoxicity in T2DM patients under long term antihyperglycemic drug therapy., (Copyright © 2010 Elsevier Ltd. All rights reserved.)