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Your search keyword '"Kirkman RL"' showing total 27 results
Start Over Author "Kirkman RL" Publisher elsevier science inc
27 results on '"Kirkman RL"'

3. Mesenteric and intraepithelial lymphocytes are insufficient to cause rejection but able to mediate lethal graft-versus-host disease in small bowel transplants.

Author

Xia W, Brandeis JM, Sayegh M, and Kirkman RL

Subjects
Animals, Antilymphocyte Serum, Chimera, Crosses, Genetic, Lymph Nodes immunology, Rats, Rats, Inbred BN, Rats, Inbred Lew, Spleen immunology, Transplantation, Heterotopic, Transplantation, Homologous, Graft Rejection immunology, Graft vs Host Disease immunology, Intestine, Small transplantation, Lymphocyte Transfusion
Published
1994

4. Effect of repetitive doses of soluble human complement receptor type 1 on survival of discordant cardiac xenografts.

Author

Xia W, Fearon DT, and Kirkman RL

Subjects
Animals, Female, Graft Rejection prevention & control, Guinea Pigs, Humans, Male, Rats, Rats, Inbred Lew, Recombinant Proteins immunology, Recombinant Proteins therapeutic use, Time Factors, Graft Survival immunology, Heart Transplantation immunology, Receptors, Complement immunology, Transplantation, Heterologous immunology
Published
1993

5. Liver disease and HCV infection after transplantation of organs from hepatitis C antibody positive donors.

Author

Pereira BJ, Milford EL, Kirkman RL, Quan S, Sayre KR, Johnson PJ, Wilber JC, and Levey AS

Subjects
Enzyme-Linked Immunosorbent Assay, Hepatitis C epidemiology, Hepatitis C Antibodies, Humans, Liver Diseases epidemiology, New England, Prevalence, Tissue Banks, Hepatitis Antibodies analysis, Hepatitis C transmission, Kidney Transplantation, Liver Diseases etiology, Tissue Donors
Published
1993

6. Insights into the mechanism of allograft acceptance in T-cell receptor (beta-chain) transgenic mice.

Author

Barrett LV, Rimm IJ, Wiens GR, Seidman JG, and Kirkman RL

Subjects
Animals, Immunosuppression Therapy, Male, Mice, Mice, Inbred A, Mice, Inbred BALB C, Mice, Inbred C57BL, Mice, Inbred Strains, Mice, Transgenic, Receptors, Antigen, T-Cell, alpha-beta genetics, Time Factors, Transplantation, Homologous, Graft Survival immunology, Heart Transplantation immunology, Immune Tolerance, Receptors, Antigen, T-Cell, alpha-beta immunology
Published
1993

7. Cytomegalovirus immune globulin for the prevention of primary CMV disease in renal transplant patients: analysis of usage under treatment IND status. The Treatment IND Study Group.

Author

Werner BG, Snydman DR, Freeman R, Rohrer R, Tilney NL, and Kirkman RL

Subjects
Adult, Cytomegalovirus Infections physiopathology, Female, Graft Rejection therapy, Humans, Immunoglobulins, Immunoglobulins, Intravenous, Immunosuppression Therapy methods, Male, Prospective Studies, Retrospective Studies, Surveys and Questionnaires, Tissue Donors, Treatment Outcome, Cytomegalovirus Infections prevention & control, Immunization, Passive, Kidney Transplantation immunology
Published
1993

8. Cyclosporine inhibits specific sIgA production against cholera toxin but not trinitrophenyl-lipopolysaccharide in small bowel transplantation.

Author

Xia W and Kirkman RL

Subjects
Animals, Cyclosporine therapeutic use, Rats, Rats, Inbred Lew, Rats, Inbred Strains, Transplantation, Homologous immunology, Transplantation, Isogeneic immunology, Antibody Formation drug effects, Cholera Toxin immunology, Cyclosporine pharmacology, Endotoxins immunology, Immunoglobulin A, Secretory biosynthesis, Intestine, Small transplantation, Lipopolysaccharides immunology
Published
1992

9. Priming the recipient abrogates the inhibitory effect of cyclosporine on specific sIgA production against cholera toxin in small bowel transplantation.

Author

Xia W and Kirkman RL

Subjects
Analysis of Variance, Animals, Cyclosporine therapeutic use, Immunoglobulin A analysis, Immunosuppression Therapy methods, Rats, Rats, Inbred Lew, Rats, Inbred Strains, Transplantation, Heterotopic, Antibody Formation, Cholera Toxin immunology, Immunoglobulin A biosynthesis, Intestine, Small transplantation, Transplantation, Homologous immunology
Published
1992

11. A randomized prospective trial of anti-Tac monoclonal antibody in human renal transplantation.

Author

Kirkman RL, Shapiro ME, Carpenter CB, McKay DB, Milford EL, Ramos EL, Tilney NL, Waldmann TA, Zimmerman CE, and Strom TB

Subjects
Azathioprine therapeutic use, Communicable Diseases complications, Cyclosporins therapeutic use, Drug Therapy, Combination, Graft Rejection, Graft Survival, Humans, Prednisone therapeutic use, Prospective Studies, Survival Analysis, Antibodies, Monoclonal therapeutic use, Immunosuppression Therapy methods, Kidney Transplantation methods, Receptors, Interleukin-2 immunology
Published
1991

12. Final analysis of primary cytomegalovirus disease prevention in renal transplant recipients with a cytomegalovirus-immune globulin: comparison of the randomized and open-label trials.

Author

Snydman DR, Werner BG, Tilney NL, Kirkman RL, Milford EL, Cho SI, Bush HL Jr, Levey AS, Strom TB, and Carpenter CB

Subjects
Adult, Antibodies, Viral administration & dosage, Antibodies, Viral analysis, Antibodies, Viral standards, Cadaver, Child, Graft Rejection, Humans, Immunization, Passive, Tissue Donors, Cytomegalovirus Infections prevention & control, Kidney Transplantation
Published
1991

15. Anti-TAC MOAB prolongs renal allografts in cynomolgus monkeys.

Author

Reed MH, Shapiro ME, Strom TB, Carpenter CB, Letvin NL, Reimann K, Weinberg DS, Waldmann TA, and Kirkman RL

Subjects
Animals, Combined Modality Therapy, Cyclosporins therapeutic use, Graft Rejection, Immunosuppression Therapy, Macaca fascicularis, Transplantation, Homologous, Antibodies, Monoclonal therapeutic use, Graft Survival, Interleukin-2 immunology, Kidney Transplantation, Receptors, Interleukin-2 immunology
Published
1989

16. Treatment with a diphtheria toxin-related interleukin 2 fusion protein prolongs cardiac allograft survival in mice.

Author

Barrett LV, Murphy JR, Strom TB, and Kirkman RL

Subjects
Animals, Male, Mice, Mice, Inbred C57BL, Mice, Inbred Strains, Mutation, Transplantation, Homologous, Diphtheria Toxin therapeutic use, Graft Survival drug effects, Heart Transplantation, Interleukin-2 therapeutic use, Recombinant Fusion Proteins therapeutic use, Recombinant Proteins therapeutic use
Published
1989

17. Long-term results of cyclosporine treatment in renal transplantation.

Author

Tilney NL, Milford EL, Carpenter CB, Lazarus JM, Strom TB, and Kirkman RL

Subjects
Azathioprine therapeutic use, Creatinine blood, Cyclosporins adverse effects, Cyclosporins blood, Graft Survival, Humans, Kidney drug effects, Kidney physiology, Long-Term Care, Postoperative Complications, Time Factors, Transplantation, Homologous, Cyclosporins therapeutic use, Kidney Transplantation
Published
1986

18. Monoclonal anti-IL-2 receptor antibody in primate renal transplantation.

Author

Shapiro ME, Kirkman RL, Reed MH, Puskas JD, Mazoujian G, Letvin NL, Carpenter CB, Milford EL, Waldmann TA, and Strom TB

Subjects
Animals, Humans, Immunosuppression Therapy, Lymphocyte Activation, Macaca fascicularis, Receptors, Interleukin-2, Antibodies, Monoclonal therapeutic use, Graft Survival, Interleukin-2 immunology, Kidney Transplantation, Receptors, Immunologic immunology
Published
1987

19. Cyclosporine potentiates the immunosuppressive effects of anti-interleukin 2 receptor monoclonal antibody therapy.

Author

Kupiec-Weglinski JW, Hahn HJ, Kirkman RL, Volk HD, Mouzaki A, DiStefano R, Tellides G, Dallman M, Morris PJ, and Strom TB

Subjects
Antigens, Differentiation, T-Lymphocyte analysis, Diabetes Mellitus, Type 1 therapy, Drug Synergism, Graft Survival drug effects, Graft vs Host Reaction, Intestine, Small transplantation, Kidney Transplantation, Receptors, Interleukin-2, Skin Transplantation, T-Lymphocytes classification, Antibodies, Monoclonal administration & dosage, Cyclosporins administration & dosage, Heart Transplantation, Immunosuppression Therapy, Islets of Langerhans Transplantation, Receptors, Immunologic immunology
Published
1988

20. Early experience with anti-Tac in clinical renal transplantation.

Author

Kirkman RL, Shapiro ME, Carpenter CB, Milford EL, Ramos EL, Tilney NL, Waldmann TA, Zimmerman CE, and Strom TB

Subjects
Clinical Trials as Topic, Cyclosporins therapeutic use, Graft Rejection, Humans, Random Allocation, Transplantation, Homologous, Antibodies, Monoclonal therapeutic use, Immunosuppression Therapy, Interleukin-2 immunology, Kidney Transplantation, Receptors, Interleukin-2 immunology
Published
1989

25. Anti-T12 monoclonal antibody therapy of acute renal allograft rejection.

Author

Milford EL, Carpenter CB, Kirkman RL, Tilney NL, Mazoujian G, Strom TB, Lazarus JM, Schlossman SF, Guttmann RD, and Lowry R

Subjects
Humans, Immunoglobulin M administration & dosage, Kidney Transplantation physiology, Skin Tests, T-Lymphocytes immunology, Transplantation, Homologous, Antibodies, Monoclonal therapeutic use, Graft Rejection immunology, Immunosuppression Therapy, Kidney Transplantation immunology
Published
1987

26. A further analysis of primary cytomegalovirus disease prevention in renal transplant recipients with a cytomegalovirus immune globulin: interim comparison of a randomized and an open-label trial.

Author

Snydman DR, Werner BG, Tilney NL, Kirkman RL, Milford EL, Cho SI, Bush HL Jr, Levey AS, Strom TB, and Carpenter CB

Subjects
Adolescent, Adult, Clinical Trials as Topic, Cytomegalovirus Infections etiology, Cytomegalovirus Infections immunology, Drug Interactions, Female, Humans, Immunoglobulins, Intravenous, Male, Middle Aged, Neutropenia etiology, Prospective Studies, Random Allocation, Syndrome, Cytomegalovirus Infections prevention & control, Immune Sera adverse effects, Immunization, Passive, Immunoglobulins, Kidney Transplantation
Published
1988

27. Stability of renal allograft recipients after conversion from cyclosporine to azathioprine.

Author

Carpenter CB, Milford EL, Kirkman RL, Strom TB, Lazarus JM, and Tilney NL

Subjects
Acute Disease, Drug Administration Schedule, Follow-Up Studies, Graft Rejection drug effects, Humans, Kidney physiopathology, Kidney Diseases chemically induced, Kidney Function Tests, Long-Term Care, Postoperative Period, Azathioprine administration & dosage, Cyclosporins administration & dosage, Kidney Diseases physiopathology, Kidney Transplantation
Abstract

Forty-eight patients with stable renal function after allotransplantation have been converted from CsA/prednisone to azathioprine/prednisone to assess the short- and long-term effects upon renal function. Virtually all patients show an initial improvement in serum creatinine levels. Three patients developed chronic renal failure after 12 to 21 months, and three died of pneumonia 7, 12, and 19 months later. The mean serum creatinine level at latest follow-up (seven to 36 months) was 2.5 +/- 1.5 mg/dL for all 48 patients. Of interest, a control group of 21 patients not converted to azathioprine had serum creatinine levels of 2.5 +/- 0.8 mg/dL, over a follow-up period of five to 25 months. It is not immediately apparent that either group will have a superior overall outcome, although patients on azathioprine seem to have more of a risk for graft loss. More data are needed with various dosage schedules, and with randomized controls.

Published
1985

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