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Your search keyword '"Agostina Congiu Castellano"' showing total 3 results
Start Over Author "Agostina Congiu Castellano" Publisher elsevier science bv
3 results on '"Agostina Congiu Castellano"'

1. Potential genotoxic effects of low-intensity ultrasound on fibroblasts, evaluated with the cytokinesis-block micronucleus assay

Author

D. Pozzi, F. Luongo, Angelico Bedini, Agostina Congiu Castellano, Claudia Giliberti, Federico Bordi, Ion Udroiu, Fabio Domenici, Raffaele Palomba, Udroiu, Ion, Fabio, Domenici, Claudia, Giliberti, Angelico, Bedini, Raffaele, Palomba, Fabio, Luongo, Deleana, Pozzi, Federico, Bordi, and Agostina Congiu, Castellano

Subjects
CBMN assay, Health, Toxicology and Mutagenesis, Biology, Micronuclei, medicine.disease_cause, Toxicology, Mice, Ultrasound, Genetics, medicine, Cytotoxic T cell, Animals, Cytotoxicity, NIH-3T3, Micronuclei, Chromosome-Defective, Settore CHIM/02 - Chimica Fisica, micronucleu, Genotoxicity, Micronucleus, 3T3 Cells, Fibroblasts, Sound, ultrasound, business.industry, genotoxicity, cbmn assay, nih-3t3, micronucleus, In vitro, Micronucleus test, Cancer research, business, Chromosome-Defective, Cytokinesis
Abstract

Although medical ultrasound offers compelling opportunities to improve therapy in principle, progress in the field has been limited because of an insufficient understanding of the potential genotoxic and cytotoxic effects of ultrasound on biological systems. This paper is mainly focused on an in vitro study of effects with respect to genotoxicity and viability induced by 1- and 3-MHz medical ultrasound in murine fibroblasts (NIH-3T3) at low-intensity exposure (spatial peak temporal average intensity Ita

Published
2014

2. Structural and permeability sensitivity of cells to low intensity ultrasound: Infrared and fluorescence evidence in vitro

Author

Fabio Domenici, Stefania Morrone, Raffaele Palomba, Federico Bordi, D. Pozzi, Angelico Bedini, Claudia Giliberti, Ion Udroiu, Agostina Congiu Castellano, Lucia Di Giambattista, Domenici, Fabio, Giliberti, Claudia, Bedini, Angelico, Palomba, Raffaele, Udroiu, Ion, Di Giambattista, Lucia, Pozzi, Deleana, Morrone, Stefania, Bordi, Federico, and Castellano Agostina, Congiu

Subjects
Cell Membrane Permeability, Spectrophotometry, Infrared, Acoustics and Ultrasonics, Membrane permeability, Cells, In Vitro Techniques, Fluorescence, Flow cytometry, chemistry.chemical_compound, Mice, Nuclear magnetic resonance, Cell uptake, FTIR spectroscopy, Fluorescence microscopy, Membrane sonoporation, Ultrasound, Animals, Cells, Cultured, Fibroblasts, Flow Cytometry, Fluoresceins, Microscopy, Fluorescence, Ultrasonics, medicine, Fluorescence microscope, membrane sonoporation, fluorescence microscopy, ftir spectroscopy, ultrasound, cell uptake, Viability assay, Fluorescein, Settore CHIM/02 - Chimica Fisica, Microscopy, Cultured, medicine.diagnostic_test, business.industry, In vitro, chemistry, Permeability (electromagnetism), Spectrophotometry, Biophysics, business, Infrared
Abstract

This work is focused on the in vitro study of the effects induced by medical ultrasound (US) in murine fibroblast cells (NIH-3T3) at a low-intensity of exposure (spatial peak temporal average intensity Ita

Published
2014

3. Characterization of solid supported lipoplexes by FTIR microspectroscopy

Author

Massimo Piccinini, Augusto Marcelli, Agostina Congiu Castellano, Stefano Belardinelli, Johanna Generosi, and Daniela Pozzi

Subjects
inorganic chemicals, education.field_of_study, Liposome, Silicon, Chemistry, infrared spectroscopy, lipid bilayer, liposome, synchrotron radiation, technology, industry, and agriculture, Cationic polymerization, chemistry.chemical_element, Infrared spectroscopy, Condensed Matter Physics, Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials, Nuclear magnetic resonance, lipids (amino acids, peptides, and proteins), Cationic liposome, Dimethyldioctadecylammonium bromide, Fourier transform infrared spectroscopy, education, Lipid bilayer, Nuclear chemistry
Abstract

We investigated, by FTIR microspectroscopy, the interaction of some cationic and helper lipids with DNA deposited on solid supports allowing the formation of ordered structures. FTIR experiments were performed using both conventional and synchrotron radiation infrared sources and by depositing the lipids on both silicon and wedged diamond plates. Cationic liposomes composed of DOTAP (1,2-dioleoyl-3-trimethylammonium–propane) or DDAB (dimethyldioctadecylammonium bromide) and one helper neutral lipid DOPC (1,2-dioleoyl-sn-glycero-3-phosphocholine) at different cationic lipid/DNA weight ratio, were studied. Spectra of the single components are compared with those obtained for both equimolar cationic–neutral mixture and lipid/DNA complexes.

Published
2007

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