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Your search keyword '"Riou, J. F."' showing total 11 results

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11 results on '"Riou, J. F."'

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1. Syntheses, biochemical and biological evaluation of staurosporine analogues from the microbial metabolite rebeccamycin.

2. Spectroscopic and biochemical characterisation of self-aggregates formed by antitumor drugs of the camptothecin family: their possible role in the unique mode of drug action.

3. Salen-anthraquinone conjugates. Synthesis, DNA-binding and cleaving properties, effects on topoisomerases and cytotoxicity.

4. Effects of two distamycin-ellipticine hybrid molecules on topoisomerase I and II mediated DNA cleavage: relation to cytotoxicity.

5. The antileukemic alkaloid fagaronine is an inhibitor of DNA topoisomerases I and II.

6. Altered topoisomerase I activity and recombination activating gene expression in a human leukemia cell line resistant to doxorubicin.

7. Sequential modifications of topoisomerase I activity in a camptothecin-resistant cell line established by progressive adaptation.

8. Study of molecular markers of resistance to m-AMSA in a human breast cancer cell line. Decrease of topoisomerase II and increase of both topoisomerase I and acidic glutathione S transferase.

9. Characterization of the topoisomerase II-induced cleavage sites in the c-myc proto-oncogene. In vitro stimulation by the antitumoral intercalating drug mAMSA.

10. Topoisomerase II-mediated DNA cleavage activity induced by ellipticines on the human tumor cell line N417.

11. The in vitro involvement of topoisomerase II in the activity of aza-ellipticine analogues is not correlated with drug activity on isolated nuclei.

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