1. Metastatic Pheochromocytoma in an Asymptomatic 12-Year-Old With von Hippel-Lindau Disease.
- Author
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Colvin A, Saltzman AF, Walker J, Bruny J, and Cost NG
- Subjects
- Adrenal Gland Neoplasms etiology, Adrenal Gland Neoplasms surgery, Asymptomatic Diseases, Child, Humans, Lung Neoplasms etiology, Lung Neoplasms surgery, Male, Pheochromocytoma etiology, Pheochromocytoma surgery, Adrenal Gland Neoplasms pathology, Lung Neoplasms secondary, Pheochromocytoma secondary, von Hippel-Lindau Disease complications
- Abstract
Pheochromocytoma is a rare chromaffin cell tumor that may be associated with a genetic predisposition, such as von Hippel-Lindau (VHL) disease. VHL is an autosomal dominant disorder that is characterized by a predisposition to multiple tumors, including retinal and central nervous system hemangioblastomas, renal cell carcinoma, and pheochromocytomas. The classic presentation of pheochromocytoma is episodic hypertension, headaches, palpitations, and diaphoresis. In the pediatric population, 40% of pheochromocytomas have a hereditary basis. We present a case of metastatic pheochromocytoma in a child with VHL and discuss the relevant current medical literature., (Copyright © 2018 Elsevier Inc. All rights reserved.)
- Published
- 2018
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