1. [Immuno-hemolytic transfusion reactions. III. Report of 61 cases].
- Author
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Le Pennec PY, Tissier AM, Mannessier L, Agulles O, Babinet J, Bidet ML, Bombail-Girard D, Cabaud JJ, Cartron J, Chiaroni J, Desaint C, Krause C, Lamy B, Meyer F, Mortelecque R, Nafissi S, Rasongles P, Schweitzer B, and Rouger P
- Subjects
- Adult, Aged, Aged, 80 and over, Blood Preservation, Clinical Laboratory Techniques, Female, Follow-Up Studies, Humans, Isoantibodies blood, Male, Medical Errors, Middle Aged, Risk Assessment, ABO Blood-Group System immunology, Blood Group Incompatibility, Erythrocytes immunology, Transfusion Reaction
- Abstract
Blood transfusion is mainly bound to immunological and infectious risks. The immunological risk originates from an incompatibility between the blood of the donor and that of the recipient; this risk remains insufficiently assessed. A multicentre study has been carried out by the French Blood Transfusion Society and the National Institute for Blood Transfusion. Sixty-one accidents due to an erythrocyte incompatibility were found: 26 cases with ABO incompatibility, and 35 cases with alloantibodies of other blood group systems. For the former category of accidents, the most frequent cause was due to a failure in the realization of the bedside ABO check. For the latter, the main problem was the achievement and the interpretation of antibody screening. The long term follow-up shows no chronic after-effects of immunological accidents. For each accident, errors have been identified and analysed. It was proven that they all originate from health care establishments.
- Published
- 1996
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