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Purpose: We investigated the effects of various biochemical agents on the etiopathogenesis of recurrent aphthous stomatitis (RAS)., Methods: We enrolled 70 RAS patients and 70 healthy volunteers. Peripheral venous blood samples were collected. We performed complete blood counts, then measured the levels of ferritin, vitamin B12, iron, magnesium, phosphorus, calcium, thyroid-stimulating hormone, T3, T4, and 25-hydroxy D3., Results: The groups did not differ in terms of age (p = 0.912) or sex (p = 0.612). The levels of ferritin and 25-hydroxy vitamin D were significantly lower in RAS patients (both p ˂ 0.05)., Conclusion: Vitamin D and/or ferritin deficiency may induce RAS. Measurements of vitamin D and ferritin may assist diagnosis and follow-up., Competing Interests: Declaration of Competing Interest The study's authors have no conflicts of interest., (Copyright © 2022 Elsevier Masson SAS. All rights reserved.)

Purpose: YouTube™ has become a widely used resource of information about health-related topics nowadays. This cross-sectional study has aimed to analyze the content and quality of YouTube™ videos on orthognathic surgery., Methods: In our study, six orthognathic surgery-related keywords (Le Fort I osteotomy, sagittal split osteotomy, jaw surgery, jaw correction surgery, orthodontic surgery, and orthognathic surgery) were used to search on YouTube™. Only the videos in English, which had visually and audibly acceptable quality and were mainly about orthognathic surgery, were chosen from the videos. A total of 360 videos were selected, the top 60 videos for each search term, and sorted according to view count. Of these videos, the first 60 videos were analyzed. Video source (independent or educational), duration, number of views, likes, and dislikes were recorded for each video. Moreover, two impartial observers evaluated the visibility, popularity, quality, usefulness, and reliability of the videos., Results: 41 of 60 videos were of independent sources while 19 of them were of educational origin. Information content of the videos was found to be insufficient. No significant difference was determined between independent and educational videos in terms of popularity, visibility, usefulness and quality analysis of the videos (p > 0.05), but a significant difference was found in terms of reliability values (p < 0.05)., Conclusion: It can be said that YouTube™ videos were not a reliable and accurate enough source of information when evaluated in terms of orthognathic surgery-related content and quality. Therefore, the information content provided by specialists and health institutions, in particular, should be increased in number, thereby making access to better quality information on orthognathic surgery easy for patients., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2022 Elsevier Masson SAS. All rights reserved.)