1. New guidelines reduce the risk of hospitalization for adult patients with uncomplicated Plasmodium falciparum malaria: An observational, multicenter, retrospective French study.
- Author
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Oceane Minka S, Cottrell G, Cot M, Hillary Minka F, Thellier M, Choquet C, and Houze S
- Subjects
- Humans, Retrospective Studies, France epidemiology, Adult, Female, Male, Middle Aged, Young Adult, Antimalarials therapeutic use, Practice Guidelines as Topic, Aged, Adolescent, Ambulatory Care statistics & numerical data, Logistic Models, Multivariate Analysis, Malaria, Falciparum epidemiology, Malaria, Falciparum prevention & control, Hospitalization statistics & numerical data
- Abstract
Objectives: We aimed to evaluate the impact of malaria declaration year (before or after 2017) on the frequency of hospitalization in metropolitan France of patients with uncomplicated non-vomiting P.falciparum malaria., Patients and Methods: An observational, multicenter, retrospective study was carried out, using the database from the French National Reference Centre for Malaria. Descriptive analysis and multivariate analysis by logistic regression were performed using the multiple imputation by chained equation method to handle missing data., Results: More than 2000 (2184) uncomplicated non-vomiting P.falciparum malaria cases were recorded. Our multivariate analysis showed an association between the year 2018 and reduced risk of hospitalization (OR: 0.89; 95% CI: 0.81-0.97)., Conclusion: Compared to 2016, during 2018 we observed a trend toward ambulatory care for patients presenting with uncomplicated non-vomiting P.falciparum malaria., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Masson SAS. All rights reserved.)
- Published
- 2024
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