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The diverse geographic, demographic, and societal factors in the Pacific Island Countries and Territories (PICTs) have contributed to unique epidemiological patterns of HIV, syphilis, and hepatitis B. Transmission can be during pregnancy, at the time of birth or via breastfeeding for HIV, and can have long-term adverse outcomes. Given the similarities in prevention of mother-to-child transmission of these infections, coordinated interventions for triple elimination are used. This systematic review has evaluated the peer-reviewed literature, grey literature, and global databases to assess the availability of data to report against elimination targets in the WHO Regional Framework for the Triple Elimination of Mother-to-Child Transmission of HIV, Hepatitis B and Syphilis in Asia and the Pacific 2018-2030. The secondary objective is to report on progress towards these targets. The findings show that none of the PICTs are on track to achieve triple elimination by 2030. Amongst the limited publicly available indicator data, there is suboptimal coverage for most indicators. It is important that there is an increase in availability of and access to antenatal care, testing, and treatment for pregnant women. Increased efforts are needed to collect data on key indicators and integrate reporting into existing systems to avoid extra burden., Funding: Leila Bell was supported by an Australian Government Research Training Program (RTP) Scholarship, Australia. Funding sources had no role in paper design, data collection, data analysis, interpretation, or writing of the paper., Competing Interests: The authors declare the following financial interests/personal relationships which may be considered as potential competing interests. Margaret Hellard received investigator-initiated funding from Gilead Science and AbbVie unrelated to this work. Jess Howell received investigator-initiated funding from Gilead Science unrelated to this work and is a Gastroenterology Society of Australia (GESA) Liver Faculty member was voted Chair for 2023. The authors also acknowledge the support to the Burnet Institute provided by the Victorian Government Operational Infrastructure Support Program. Jane S Hocking received a fellowship from National Health and Medical Research Council which funded partial salary paid to the University of Melbourne., (© 2023 Published by Elsevier Ltd.)

The Pacific Island Countries and Territories (PICTs) have experienced the coronavirus disease (COVID-19) pandemic in different ways and with different timelines, with some experiencing large outbreaks leading to high levels of morbidity and mortality with significant strain on health systems, while others have had no local transmission or delayed transmission until after vaccine rollouts started. Regardless of COVID-19 trends, the pandemic has had a large impact on the social, political, and economic landscape in the Pacific, the effects of which are still being understood. However, the pandemic has also put renewed focus and investment into public health systems and provided an opportunity for the PICTs to build on existing systems and recent capacity strengthening to improve public health in the Region., Funding: Leila Bell was supported by an Australian Government Research Training Program (RTP) Scholarship. Other funding sources had no role in paper design, data collection, data analysis, interpretation, or writing of the paper., Competing Interests: The authors declare the following financial interests/personal relationships which may be considered as potential competing interests. Margaret Hellard received investigator-initiated funding from Gilead Science and AbbVie unrelated to this work. Mark Stoové received consultancy funding from Gilead Sciences and received investigator-initiated funding from Gilead Science and AbbVie unrelated to this work. The authors also acknowledge the support to the Burnet Institute provided by the Victorian Government Operational Infrastructure Support Program., (© 2022 The Author(s).)

Competing Interests: The authors have no conflict of interest to declare