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30 results on '"Valente R"'

6. T03.01.2 STARK STUDY: MACHINE LEARNING APPROACH TO PREDICT POST-ERCP PANCREATITIS IN AN INTERNATIONAL MULTICENTER PROSPECTIVE COHORT STUDY

Author

Archibugi, L., Ciarfaglia, G., Cárdenas-Jaén, K., Poropat, G., Korpela, T., Maisonneuve, P., Aparicio, J.R., Casellas, J.A., Arcidiacono, P.G., Mariani, A., Stimac, D., Hauser, G., Udd, M., Kylänpää, L., Rainio, M., Di Giulio, E., Vanella, G., Lohr, M., Valente, R., Arnelo, U., De Pretis, N., Gabbrielli, A., Brozzi, L., De-Madaria, E., and Capurso, G.

Published
2020
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7. Geomorphological features of the archaeological marine area of Sinuessa in Campania, southern Italy

Author

Pennetta, M, Stanislao, C, D'Ambrosio, V, Marchese, F, Minopoli, C, Trocciola, A, Valente, R, Donadio, C, Donadio, C., Pennetta, M, Stanislao, C, D'Ambrosio, V, Marchese, F, Minopoli, C, Trocciola, A, Valente, R, Donadio, C, and Donadio, C.

Abstract

Submarine surveys carried out since the'90s along the coastland of Sinuessa allowed us to draw up a geomorphological map with archaeological findings. Along the sea bottom, 650 m off and −7 m depth, a Campanian Ignimbrite bedrock was detected: dated ∼39 kyr BP, its position is incompatible with the current sea level. Towards the northern edge of the shoal, a depressed area with 24 cubic elements in concrete was surveyed. These artefacts (pilae) are typical of Roman maritime structures widespread along the southernmost Phlegrean coast. Beachrocks and accessory landforms at the same depth of bedrock suggest that this was emerging and attended by man in Roman times, even for activities related to port facilities. Submerged palaeo-channels, in alignment of current watercourses on the mainland, dissect the shoal. These channels were moulded in subaerial environment during Würm glaciation, following the tuff deposition, and then were drowned by sea-level rise. The northernmost channel, next to the pilae, likely allowed transit and manoeuvring of Roman ships. The discovery along the seabed of a large stump of lead anchor, hundreds of Roman amphorae and fragments, as well as of a depression of millstone, confirm this finding. Probably the sinuous physiography favored the choice of this site for the docking of Sinuessa, as sheltered from storms.

Published
2016

30. Clinical characteristics and long-term outcomes following pancreatic injury - An international multicenter cohort study.

Author

Meijer LL, Vaalavuo Y, Regnér S, Sallinen V, Lemma A, Arnelo U, Valente R, Westermark S, An D, Moir JAG, Irwin EA, Biesel EA, Hopt UT, Fichtner-Feigl S, Wittel UA, Weniger M, Karle H, Bloemers FW, Sutton R, Charnley RM, Ruess DA, and Szatmary P

Abstract

Background: Trauma to the pancreas is rare but associated with significant morbidity. Currently available management guidelines are based on low-quality evidence and data on long-term outcomes is lacking. This study aimed to evaluate clinical characteristics and patient-reported long-term outcomes for pancreatic injury., Methods: A retrospective cohort study evaluating treatment for pancreatic injury in 11 centers across 5 European nations over >10 years was performed. Data relating to pancreatic injury and treatment were collected from hospital records. Patients reported quality of life (QoL), changes to employment and new or ongoing therapy due to index injury., Results: In all, 165 patients were included. The majority were male (70.9%), median age was 27 years (range: 6-93) and mechanism of injury predominantly blunt (87.9%). A quarter of cases were treated conservatively; higher injury severity score (ISS) and American Association for the Surgery of Trauma (AAST) pancreatic injury scores increased the likelihood for surgical, endoscopic and/or radiologic intervention. Isolated, blunt pancreatic injury was associated with younger age and pancreatic duct involvement; this cohort appeared to benefit from non-operative management. In the long term (median follow-up 93; range 8-214 months), exocrine and endocrine pancreatic insufficiency were reported by 9.3% of respondents. Long-term analgesic use also affected 9.3% of respondents, with many reported quality of life problems (QoL) potentially attributable to side-effects of opiate therapy. Overall, impaired QoL correlated with higher ISS scores, surgical therapy and opioid analgesia on discharge., Conclusions: Pancreatic trauma is rare but can lead to substantial short- and long-term morbidity. Near complete recovery of QoL indicators and pancreatic function can occur despite significant injury, especially in isolated, blunt pancreatic injury managed conservatively and when early weaning off opiate analgesia is achieved., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2023 The Authors.)

Published
2023
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