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7. Optimal efficacy of interferon-free HCV retreatment after protease inhibitor failure in real life

8. Natural HCV resistance is common in Italy and differently associated to genotypes

9. Multiclass HCV resistance to interferon-free direct acting antivirals regimens in real life failures advocates for tailored second-line therapies

10. HCV resistance test guided retreatments after protease inhibitors failures can induce maximal efficacy rate in real-life

11. Presence of resistance associated variants in patients with virological failure to new direct acting antivirals and requirement of unconventional regimens for re-treatment

12. Clinical relevance of accurate HCV genotype and subtype assignment by NS3/NS5A/NS5B direct sequencing in the era of new direct acting antiviral agents

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