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Start Over Author "Minana A." Publisher elsevier ireland ltd
24 results on '"Minana A."'

1. Effect of ischemic postconditioning on microvascular obstruction in reperfused myocardial infarction. Results of a randomized study in patients and of an experimental model in swine

Author

Bodi, Vicente, Ruiz-Nodar, Juan M., Feliu, Eloisa, Minana, Gema, Nunez, Julio, Husser, Oliver, Martinez-Elvira, Javier, Ruiz, Amparo, Bonanad, Clara, Monmeneu, Jose V., Lopez-Lereu, Maria P., Forteza, Maria J., de Dios, Elena, Hervas, Arantxa, Moratal, David, Gomez, Cristina, Mainar, Luis, Sanchis, Juan, Mainar, Vicente, Valencia, Jose, Diaz, Ana, Noguera, Inmaculada, Chaustre, Fabian, and Chorro, Francisco J.

Published
2014
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6. Long-term prognostic implications of revascularization in patients with known or suspected chronic coronary syndromes without ischemia in vasodilator stress cardiovascular magnetic resonance

Author

Minana G, Nunez J, Marcos-Garces V, Gavara J, Rios-Navarro C, and Bodi V

Abstract

AIMS: In this study, we evaluated the association between symptoms-guided revascularization occurred within three months following a negative vasodilator stress cardiovascular magnetic resonance (negative stress-CMR) and long-term adverse events in patients with known or suspected chronic coronary syndrome (CCS). METHODS: We retrospectively evaluated 3517 patients in which the stress first-pass perfusion imaging revealed no ischemia. The primary endpoint was the composite of death, spontaneous myocardial infarction, heart failure (HF), or stroke. The association between symptoms-guided revascularization after a negative stress-CMR and the endpoint was assessed using the multivariable Cox proportional hazard regression model. RESULTS: The mean age was 64.7 ± 11.9 years and 45.4% were females. Coronary angiography and revascularization following a negative stress-CMR were performed in 176 (5%) and 59 (1.7%) patients. At a median follow-up of 4.8 years (2.0-8.2), 529 (15%) patients experienced the primary endpoint (2.0 per 100 person-years). Revascularization following a negative CMR was associated with a higher incidence of the composite (4.85 vs. 1.96 per 100 person-years, p < 0.001) and each of the isolated components of the endpoint, except for the HF endpoint, in which differences were borderline significant. After multivariate adjustment, revascularization remained associated with an excess of risk (HR = 2.01, 95% CI:1.21-3.30; p = 0.007). CONCLUSIONS: In CCS patients with persistent symptoms but without evidence of ischemia in vasodilator stress CMR, revascularization was associated with a higher risk of adverse clinical events.

Published
2021

7. Sex-differential effect of frailty on long-termmortality in elderly patients after an acute coronary syndrome

Author

Nunez J, Palau P, Sastre C, D'Ascoli G, Ruiz V, Bonanad C, Minana G, Nunez E, and Sanchis J

Subjects
Frailty, Women, Acute coronary syndromes, Prognosis
Abstract

Background: The potential sex-differential effect of frailty in patients with acute coronary syndromes (ACS) has not been well-evaluated. We sought to examine the sex-differential association between frailty status on long-term mortality in elderly patients with an ACS. Methods and results: This is a prospective observational single-center study that included 488 elderly patients (>65 years) hospitalized for ACS who survived the index hospitalization. Multivariate Cox regression was used to determine the association among the exposures (interaction of sex with Fried score and sex with Fried >= 3) and all-cause mortality. The mean age of the sample was 78 +/- 7 years; 41% were female and the median Fried score was higher in women [3 (2-3) vs. 2 (1-2) points, p < 0.001]. At a median follow-up of 3.12 years (IQR:1.38-5.13), 182 deaths (37.3%) were registered. The association of Fried >= 3 with mortality varied across sex (p-value for interaction = 0.022). In males, Fried >= 3 was independently associated with all-cause death (HR = 1.89; CI 95%:1.25-2.85, p = 0.003). However, it showed a neutral effect on women (HR = 0.92; CI 95%:0.57-1.49, p = 0.726). Conclusions: In this work, we found that the frailty status assessed by Fried score was independently associated with mortality in elderly males but not in females with ACS. (C) 2019 Elsevier B.V. All rights reserved.

Published
2020

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