29 results on '"Southall, Noel"'
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2. Activation of mitochondrial TRAP1 stimulates mitochondria-lysosome crosstalk and correction of lysosomal dysfunction
3. Validating ADME QSAR Models Using Marketed Drugs
4. A large scale high-throughput screen identifies chemical inhibitors of phosphatidylinositol 4-kinase type II alpha
5. Discovery of a Positive Allosteric Modulator of the Thyrotropin Receptor: Potentiation of Thyrotropin-Mediated Preosteoblast Differentiation In Vitro
6. SU9516 Increases α7β1 Integrin and Ameliorates Disease Progression in the mdx Mouse Model of Duchenne Muscular Dystrophy
7. Small Molecule, NSC95397, Inhibits the CtBP1-Protein Partner Interaction and CtBP1-Mediated Transcriptional Repression
8. High-Throughput Viability Assay Using an Autonomously Bioluminescent Cell Line with a Bacterial Lux Reporter
9. Allosteric Inhibitors of the Eya2 Phosphatase Are Selective and Inhibit Eya2-mediated Cell Migration
10. An Overview of the Challenges in Designing, Integrating, and Delivering BARD: A Public Chemical-Biology Resource and Query Portal for Multiple Organizations, Locations, and Disciplines
11. A TRP Channel in the Lysosome Regulates Large Particle Phagocytosis via Focal Exocytosis
12. Targeting IRAK1 as a Therapeutic Approach for Myelodysplastic Syndrome
13. Identification of Small-Molecule Agonists of Human Relaxin Family Receptor 1 (RXFP1) by Using a Homogenous Cell-Based cAMP Assay
14. A high-throughput screening assay using Krabbe disease patient cells
15. Identification of a Selective Small-Molecule Inhibitor Series Targeting the Eyes Absent 2 (Eya2) Phosphatase Activity
16. δ-Tocopherol Reduces Lipid Accumulation in Niemann-Pick Type C1 and Wolman Cholesterol Storage Disorders
17. Identification of quaternary ammonium compounds as potent inhibitors of hERG potassium channels
18. Dose-Response Modeling of High-Throughput Screening Data
19. A new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel
20. Monitoring Compound Integrity With Cytochrome P450 Assays and qHTS
21. An AlphaScreen™-Based High-Throughput Screen to Identify Inhibitors of Hsp90-Cochaperone Interaction
22. A new resorufin-based α-glucosidase assay for high-throughput screening
23. A Cell-Based PDE4 Assay in 1536-Well Plate Format for High-Throughput Screening
24. Quantitative High-Throughput Screening Using a Live-Cell cAMP Assay Identifies Small-Molecule Agonists of the TSH Receptor
25. Membrane recognition and substrate binding mechanism of PIP4Kγ kinase from molecular simulations
26. A high-throughput screening assay using Krabbe disease patient cells
27. δ-Tocopherol reduces lipid accumulation in Niemann-Pick type C1 and Wolman cholesterol storage disorders.
28. High-Throughput Screening for Modulators of the D2 Dopamine Receptor Yields Unique and Selective Pharmacological Chemotypes
29. 155. High Throughput screen for identifying small molecule modulators of alpha-glucosidase for the potential treatment of Pompe disease
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