15 results on '"Simon, Adam J."'
Search Results
2. Decrease in age-adjusted cerebrospinal fluid β-secretase activity in Alzheimer's subjects
3. Biochemical and cell-based assays for characterization of BACE-1 inhibitors
4. A cell-based β-lactamase reporter gene assay for the identification of inhibitors of hepatitis C virus replication
5. A brain computer interface to detect Alzheimer's disease
6. Evidence for dose-dependent neurotoxicity of amyloid-β oligomers/Aβ-derived diffusible ligands generated from physiological processing of transgenic human APP in situ in mouse brain
7. P3-263: The kinesin light chain 1 polymorphism rs8702 is associated with elevated CSF levels of secreted forms of amyloid precursor protein
8. P3-094: Three novel CSF assays expand a core panel of CSF biomarkers: BACE activity, oligomeric Aβ and homocysteine assessed in pathologically confirmed Alzheimer subjects within the Oxford project to investigate memory and aging (Optima) cohort
9. P3-077: Cerebrospinal fluid levels of Alzheimer's disease biomarkers in term and pre-term newborn infants
10. O3-02-06: Elevated cerebrospinal fluid BACE1 activity in incipient Alzheimer's disease
11. O1-04-02: Significant Aβ lowering in CSF and plasma after oral administration of a potent small molecule BACE1 inhibitor in non-human primates
12. P2-165: A multi-analyte panel of six CSF biomarkers classifies AD and control in pathologically confirmed Alzheimer subjects within the OPTIMA cohort
13. P2-069: Nonhuman primate model for prediction of human Aβ effects. Targeting γ-secretase: Effects of enzyme inhibition vs. modulation of cleavage specificity on CSF and plasma Aβ in conscious rhesus monkeys
14. P2-137 Secretase inhibitors reduce amyloid production in primary neurons from novel MWP HUAPP KI mice
15. P2-066 A genetically engineered mouse model with an enhanced beta-secretase substrate exhibits increased amyloid generation
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