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12 results on '"Montin, Davide"'

3. Long-term follow-up of 168 patients with X-linked agammaglobulinemia reveals increased morbidity and mortality

Author

Lougaris, Vassilios, Soresina, Annarosa, Baronio, Manuela, Montin, Davide, Martino, Silvana, Signa, Sara, Volpi, Stefano, Zecca, Marco, Marinoni, Maddalena, Baselli, Lucia Augusta, Dellepiane, Rosa Maria, Carrabba, Maria, Fabio, Giovanna, Putti, Maria Caterina, Cinetto, Francesco, Lunardi, Claudio, Gazzurelli, Luisa, Benvenuto, Alessio, Bertolini, Patrizia, Conti, Francesca, Consolini, Rita, Ricci, Silvia, Azzari, Chiara, Leonardi, Lucia, Duse, Marzia, Pulvirenti, Federica, Milito, Cinzia, Quinti, Isabella, Cancrini, Caterina, Finocchi, Andrea, Moschese, Viviana, Cirillo, Emilia, Crescenzi, Ludovica, Spadaro, Giuseppe, Marasco, Carolina, Vacca, Angelo, Cardinale, Fabio, Martire, Baldassare, Trizzino, Antonino, Licciardello, Maria, Cossu, Fausto, Di Matteo, Gigliola, Badolato, Raffaele, Ferrari, Simona, Giliani, Silvia, Pession, Andrea, Ugazio, Alberto, Pignata, Claudio, and Plebani, Alessandro

Published
2020
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4. Immunophenotype Anomalies Predict the Development of Autoimmune Cytopenia in 22q11.2 Deletion Syndrome

Author

Montin, Davide, Marolda, Agostina, Licciardi, Francesco, Robasto, Francesca, Di Cesare, Silvia, Ricotti, Emanuela, Ferro, Francesca, Scaioli, Giacomo, Giancotta, Carmela, Amodio, Donato, Conti, Francesca, Giardino, Giuliana, Leonardi, Lucia, Ricci, Silvia, Volpi, Stefano, Baselli, Lucia Augusta, Azzari, Chiara, Bossi, Grazia, Consolini, Rita, Dellepiane, Rosa Maria, Duse, Marzia, Gattorno, Marco, Martire, Baldassarre, Putti, Maria Caterina, Soresina, Annarosa, Plebani, Alessandro, Ramenghi, Ugo, Martino, Silvana, Pignata, Claudio, and Cancrini, Caterina

Published
2019
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6. Exposure to Gastric Acid Inhibitors Increases the Risk of Infection in Preterm Very Low Birth Weight Infants but Concomitant Administration of Lactoferrin Counteracts This Effect

Author

Di Comite, Amelia, Borghesi, Alessandro, Tzialla, Chryssoula, Agriesti, Giovanni, Arisio, Riccardo, Franco, Caterina, Guardione, Roberta, Boano, Elena, Catarinella, Alessia, Romano, Cristina, Monetti, Cesare, Sala, Ugo, Carbonara, Caterina, Mastretta, Emmanuele, Del Sordo, Paola, Priolo, Claudio, Galletto, Paolo, Campagnoli, Francesca, Vivalda, Mauro, Bonfante, Giuseppina, Gomirato, Giovanna, Montin, Davide, Camilla, Roberta, Messina, Alessandro, Pieretto, Marta, Cipolla, Domenico, Giuffrè, Mario, Corsello, Giovanni, Natale, Fabio, Vetrano, Gennaro, Tridapalli, Elisabetta, Faldella, Giacomo, Grazia Capretti, Maria, Paolillo, PierMichele, Picone, Simonetta, Lacerenza, Serafina, Gargano, Giancarlo, Magnani, Cristiana, Sergio Saia, Onofrio, Della Casa, Elena, Manzoni, Paolo, García Sánchez, Ruben, Meyer, Michael, Stolfi, Ilaria, Pugni, Lorenza, Messner, Hubert, Cattani, Silvia, Betta, Pasqua Maria, Memo, Luigi, Decembrino, Lidia, Bollani, Lina, Rinaldi, Matteo, Fioretti, Maria, Quercia, Michele, Maule, Milena, Tavella, Elena, Mussa, Alessandro, Laforgia, Nicola, Mosca, Fabio, Magaldi, Rosario, Mostert, Michael, and Farina, Daniele

Published
2018
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7. Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis

Author

Meazza, Raffaella, Tuberosa, Claudia, Cetica, Valentina, Falco, Michela, Parolini, Silvia, Grieve, Sam, Griffiths, Gillian M., Sieni, Elena, Marcenaro, Stefania, Micalizzi, Concetta, Montin, Davide, Fagioli, Franca, Moretta, Alessandro, Mingari, Maria C., Moretta, Lorenzo, Notarangelo, Luigi D., Bottino, Cristina, Aricò, Maurizio, and Pende, Daniela

Published
2014
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8. B-cell development and functions and therapeutic options in adenosine deaminase–deficient patients

Author

Brigida, Immacolata, Sauer, Aisha V., Ferrua, Francesca, Giannelli, Stefania, Scaramuzza, Samantha, Pistoia, Valentina, Castiello, Maria Carmina, Barendregt, Barbara H., Cicalese, Maria Pia, Casiraghi, Miriam, Brombin, Chiara, Puck, Jennifer, Müller, Klaus, Notarangelo, Lucia Dora, Montin, Davide, van Montfrans, Joris M., Roncarolo, Maria Grazia, Traggiai, Elisabetta, van Dongen, Jacques J.M., van der Burg, Mirjam, and Aiuti, Alessandro

Published
2014
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9. Persistence of disease flares is associated with an inadequate colchicine dose in familial Mediterranean fever: A national multicenter longitudinal study

Author

Bustaffa, Marta, Mazza, Francesca, Sutera, Diana, Carrabba, Maria Domenica, Alessio, Maria, Cantarini, Luca, Obici, Laura, Rigante, Donato, Maggio, Maria Cristina, Insalaco, Antonella, Simonini, Gabriele, Cattalini, Marco, Conti, Giovanni, Olivieri, Alma Nunzia, Barone, Patrizia, Miniaci, Angela, Moressa, Valentina, Magnolia, Maria Greca, Breda, Luciana, Montin, Davide, Spagnolo, Alessandra, Fabio, Giovanna, Orlando, Francesca, Gaggiano, Carla, Mussinelli, Roberta, Capozio, Giovanna, Celani, Camilla, Marrani, Edoardo, Ricci, Francesca, Calzatini, Francesco, Lancieri, Maddalena, Ruperto, Nicolino, Gattorno, Marco, and Gallizzi, Romina

Published
2021
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12. Immunophenotype anomalies predict the development of autoimmune cytopenia in 22q11.2 deletion syndrome

Author

Stefano Volpi, Francesca Conti, Baldassarre Martire, Emanuela Ricotti, Silvia Ricci, Ugo Ramenghi, Francesco Licciardi, Donato Amodio, Carmela Giancotta, Grazia Bossi, Chiara Azzari, Agostina Marolda, Marco Gattorno, Francesca Robasto, Giuliana Giardino, Caterina Cancrini, Claudio Pignata, Marzia Duse, Alessandro Plebani, Lucia Leonardi, Rosa Maria Dellepiane, Annarosa Soresina, Rita Consolini, Silvana Martino, Maria Caterina Putti, Francesca Ferro, Davide Montin, Giacomo Scaioli, Lucia Augusta Baselli, Silvia Di Cesare, Montin, Davide, Marolda, Agostina, Licciardi, Francesco, Robasto, Francesca, Di Cesare, Silvia, Ricotti, Emanuela, Ferro, Francesca, Scaioli, Giacomo, Giancotta, Carmela, Amodio, Donato, Conti, Francesca, Giardino, Giuliana, Leonardi, Lucia, Ricci, Silvia, Volpi, Stefano, Baselli, Lucia Augusta, Azzari, Chiara, Bossi, Grazia, Consolini, Rita, Dellepiane, Rosa Maria, Duse, Marzia, Gattorno, Marco, Martire, Baldassarre, Caterina Putti, Maria, Soresina, Annarosa, Plebani, Alessandro, Ramenghi, Ugo, Martino, Silvana, Pignata, Claudio, and Cancrini, Caterina

Subjects
Male, Hemolytic anemia, T-Lymphocytes, Lymphocyte, NK cells, Gastroenterology, 0302 clinical medicine, Immunophenotyping, Immunology and Allergy, 030212 general & internal medicine, CD4 naïve cell, Child, hemolytic anemia, B-Lymphocytes, thrombocytopenic purpura, 22q11.2 deletion syndrome, Autoimmune cytopenia, B immunophenotype, CD4 naïve cells, DiGeorge syndrome, Switched memory B cells, T immunophenotype, Thrombocytopenic purpura, Middle Aged, diGeorge syndrome, medicine.anatomical_structure, Child, Preschool, Female, Switched memory B cell, autoimmune cytopenia, switched memory B cells, Autoimmune hemolytic anemia, Adolescent, Adult, Autoimmune Diseases, Case-Control Studies, DiGeorge Syndrome, Humans, Lymphopenia, Young Adult, medicine.medical_specialty, Naive B cell, 03 medical and health sciences, Internal medicine, medicine, NK cell, Preschool, Survival rate, Settore MED/38 - Pediatria Generale e Specialistica, Cytopenia, business.industry, medicine.disease, 030228 respiratory system, business
Abstract

Background Patients with 22q11.2 deletion syndrome (22q11.2DS) may develop severe thrombocytopenic purpura and hemolytic anemia. There are no reliable predictors for the development of hematologic autoimmunity (HA) in these patients. Objective To describe the peculiar B and T subpopulation defects in patients with 22q11DS who have developed HA and test if these defects precede the development of HA. Methods We performed a case-control multicenter study. Patients with HA were compared with a control population of 22q11.2DS without HA (non-HA). A complete immunological evaluation was performed at diagnosis and at the last follow-up including extensive T and B phenotypes. Results Immunophenotype at the last follow-up was available in 23 HA and 45 non-HA patients. HA patients had significantly decreased percentage of naive CD4+ cells (26.8% vs 43.2%, P = .003) and recent thymic emigrants (48.6% vs 80.5%, P = .046); decreased class-switched B cells (2.0% vs 5.9%, P = .04) and increased naive B cells (83.5% vs 71.4%, P = .02); increased CD16+/56+ both in absolute number (312 vs 199, P = .009) and percentage (20.0% vs 13.0%, P = .03). Immunophenotype was performed in 36 patients (11 HA and 25 non-HA) at diagnosis. Odds ratio (OR) of immune cytopenia were estimated for both CD4 naive ≤30% (OR 14.0, P = .002) and switched memory B cells ≤2% (OR 44.0, P = .01). The estimated survival curves reached statistical significance, respectively, P = .0001 and P = .002. Conclusions Among patients with 22q11.2DS, those with HA have characteristic lymphocyte anomalies that appear considerably before HA onset. Systematic immunophenotyping of patients with 22q11.2DS at diagnosis is advisable for early identification of patients at risk for this severe complication.

Published
2019

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