63 results on '"Merghoub, Taha'
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2. TYRP1 directed CAR T cells control tumor progression in preclinical melanoma models
3. Preoperative immune checkpoint inhibition and cryoablation in early-stage breast cancer
4. Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer
5. MCT4-dependent lactate secretion suppresses antitumor immunity in LKB1-deficient lung adenocarcinoma
6. Lineage tracing reveals clonal progenitors and long-term persistence of tumor-specific T cells during immune checkpoint blockade
7. T cell immunotherapies engage neutrophils to eliminate tumor antigen escape variants
8. The ectonucleotidase CD39 identifies tumor-reactive CD8+ T cells predictive of immune checkpoint blockade efficacy in human lung cancer
9. A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation
10. Pharmacologic modulation of RNA splicing enhances anti-tumor immunity
11. Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors
12. Tim-4+ cavity-resident macrophages impair anti-tumor CD8+ T cell immunity
13. Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma
14. Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction
15. Noninvasive Early Identification of Therapeutic Benefit from Immune Checkpoint Inhibition
16. Silibinin down-regulates PD-L1 expression in nasopharyngeal carcinoma by interfering with tumor cell glycolytic metabolism
17. Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer
18. Chapter 6 - Surrogate assessment of brain health using longitudinal measures of blood-based biomarkers in short-duration human spaceflight
19. Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade
20. Pre-existing Immunity to Oncolytic Virus Potentiates Its Immunotherapeutic Efficacy
21. The Dietary Supplement Chondroitin-4-Sulfate Exhibits Oncogene-Specific Pro-tumor Effects on BRAF V600E Melanoma Cells
22. Heterogeneous Tumor-Immune Microenvironments among Differentially Growing Metastases in an Ovarian Cancer Patient
23. HMG-CoA synthase 1 is a synthetic lethal partner of BRAFV600E in human cancers
24. Phenformin Enhances the Efficacy of ERK Inhibition in NF1-Mutant Melanoma
25. Prevention of Dietary-Fat-Fueled Ketogenesis Attenuates BRAF V600E Tumor Growth
26. Clonal Abundance of Tumor-Specific CD4+ T Cells Potentiates Efficacy and Alters Susceptibility to Exhaustion
27. An MHC-restricted antibody-based chimeric antigen receptor requires TCR-like affinity to maintain antigen specificity
28. Tumor-Expressed IDO Recruits and Activates MDSCs in a Treg-Dependent Manner
29. Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses
30. Metabolic Rewiring by Oncogenic BRAF V600E Links Ketogenesis Pathway to BRAF-MEK1 Signaling
31. Anaphylaxis caused by repetitive doses of a GITR agonist monoclonal antibody in mice
32. Broad-Spectrum Therapeutic Suppression of Metastatic Melanoma through Nuclear Hormone Receptor Activation
33. List of contributors
34. Relief of Profound Feedback Inhibition of Mitogenic Signaling by RAF Inhibitors Attenuates Their Activity in BRAFV600E Melanomas
35. Having the cake and eating it? Clofazimine boosts immunotherapy while limiting side effects
36. Curbing Tregs’ (Lack of) Enthusiasm
37. Cyclophosphamide enhances immunity by modulating the balance of dendritic cell subsets in lymphoid organs
38. LRF Is an Essential Downstream Target of GATA1 in Erythroid Development and Regulates BIM-Dependent Apoptosis
39. Mechanisms of Immunization Against Cancer Using Chimeric Antigens
40. A Pilot Study Evaluating Lenalidomide and CC-486 in Combination with Radiotherapy for Patients with Plasmacytoma (LENAZART study)
41. Chapter Three - In vitro assays for effector T cell functions and activity of immunomodulatory antibodies
42. Surgical stress promotes IL-6–driven tumor progression in ovarian cancer (047)
43. Oncolytic immunotherapy with recombinant Newcastle disease virus-encoding interleukin-12 in ovarian cancer mouse models (046)
44. Efferent immune-mechanical activities reflect cell function and state
45. Therapeutic antibody activation of the glucocorticoid-induced TNF receptor by a clustering mechanism
46. Plzf Mediates Transcriptional Repression of HoxD Gene Expression through Chromatin Remodeling
47. Atypical t(15;17)(q13;q12) in a patient with all- trans retinoic acid refractory secondary acute promyelocytic leukemia: : a case report and review of the literature
48. Modeling Acute Promyelocytic Leukemia in the Mouse: New Insights in the Pathogenesis of Human Leukemias
49. Chapter One - The New Era of Cancer Immunotherapy: Manipulating T-Cell Activity to Overcome Malignancy
50. Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses
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