52 results on '"Denis, Cécile V."'
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2. Fitusiran reduces bleeding in factor X–deficient mice
3. A small-molecule hemostatic agent for the reversal of direct oral anticoagulant–induced bleeding
4. How unique structural adaptations support and coordinate the complex function of von Willebrand factor
5. Angiopoietin-2 binds to multiple interactive sites within von Willebrand factor
6. Transplacental delivery of therapeutic proteins by engineered immunoglobulin G: a step toward perinatal replacement therapy
7. Efficacy of platelet-inspired hemostatic nanoparticles on bleeding in von Willebrand disease murine models
8. A nanobody against the VWF A3 domain detects ADAMTS13-induced proteolysis in congenital and acquired VWD
9. ADP receptor P2Y12 is the capstone of the cross-talk between Ca2+ mobilization pathways dependent on Ca2+ ATPases sarcoplasmic/endoplasmic reticulum type 3 and type 2b in platelets
10. Thrombin generation on vascular cells in the presence of factor VIII and/or emicizumab
11. A gain‐of‐function filamin A mutation in mouse platelets induces thrombus instability
12. Antithrombotic potential of a single‐domain antibody enhancing the activated protein C‐cofactor activity of protein S
13. New insights into regulation of αIIbβ3 integrin signaling by filamin A
14. Camelid‐derived single‐chain antibodies in hemostasis: Mechanistic, diagnostic, and therapeutic applications
15. Development and characterization of single‐domain antibodies neutralizing protease nexin‐1 as tools to increase thrombin generation
16. Measuring beta‐galactose exposure on platelets: Standardization and healthy reference values
17. A single‐domain antibody that blocks factor VIIa activity in the absence but not presence of tissue factor
18. Targeting protease nexin-1, a natural anticoagulant serpin, to control bleeding and improve hemostasis in hemophilia
19. Disrupted filamin A/αIIbβ3 interaction induces macrothrombocytopenia by increasing RhoA activity
20. The von Willebrand factor Tyr2561 allele is a gain-of-function variant and a risk factor for early myocardial infarction
21. Structure and dynamics of the platelet integrin-binding C4 domain of von Willebrand factor
22. A mutation of the human EPHB2 gene leads to a major platelet functional defect
23. Advances in Clinical and Basic Science of Coagulation: Illustrated abstracts of the 9th Chapel Hill Symposium on Hemostasis
24. Emicizumab, a bispecific antibody recognizing coagulation factors IX and X: how does it actually compare to factor VIII?
25. Complex formation with pentraxin-2 regulates factor X plasma levels and macrophage interactions
26. MAGT1 deficiency in XMEN disease is associated with severe platelet dysfunction and impaired platelet glycoprotein N-glycosylation
27. Macrophage receptor SR-AI is crucial to maintain normal plasma levels of coagulation factor X
28. Imlifidase, a new option to optimize the management of patients with hemophilia A on emicizumab
29. Impaired platelet activation and cAMP homeostasis in MRP4-deficient mice
30. von Willebrand factor biosynthesis, secretion, and clearance: connecting the far ends
31. Von Willebrand factor and cancer: Another piece of the puzzle
32. Accelerated uptake of VWF/platelet complexes in macrophages contributes to VWD type 2B–associated thrombocytopenia
33. Mutations in the A3 domain of Von Willebrand factor inducing combined qualitative and quantitative defects in the protein
34. A murine model to characterize the antithrombotic effect of molecules targeting human von Willebrand factor
35. TaSER: Combining forces to stop the clot
36. Macrophage LRP1 contributes to the clearance of von Willebrand factor
37. Mutation and ADAMTS13-dependent modulation of disease severity in a mouse model for von Willebrand disease type 2B
38. In vivo modulation of a dominant‐negative variant in mouse models of von Willebrand disease type 2A
39. Macrophages contribute to the cellular uptake of von Willebrand factor and factor VIII in vivo
40. Altered thrombus formation in von Willebrand factor–deficient mice expressing von Willebrand factor variants with defective binding to collagen or GPIIbIIIa
41. Von Willebrand factor C1C2 domain is involved in platelet adhesion to polymerized fibrin at high shear rate
42. A factor VIII–nanobody fusion protein forming an ultrastable complex with VWF: effect on clearance and antibody formation
43. Localized reduction of atherosclerosis in von Willebrand factor–deficient mice
44. Pas de deux between VWF and ADAMTS13
45. Design and Characterization of FLT210, a Potent Next Generation AAV-hFVIII Vector Candidate
46. The Von Willebrand Factor Tyr2561 Allele Is a Gain-of-Function Variant and a Potential Risk Factor for Early Myocardial Infarction
47. Platelet Desialylation Is a Novel Mechanism of Thrombocytopenia during Mechanical Circulatory Assistance
48. Antibody-Based Protection of von Willebrand Factor Degradation
49. Mechanisms and Therapeutic Modulation of the Bleeding Tendency in Genetically-Engineered Von Willebrand Disease Type 2B Mice
50. VWF clearance: it's glycomplicated
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