7 results on '"Rubinstein, Marcelo"'
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2. Mouse models for V103I and I251L gain of function variants of the human MC4R display decreased adiposity but are not protected against a hypercaloric diet
3. Hypothalamic Pomc expression restricted to GABAergic neurons suppresses Npy overexpression and restores food intake in obese mice
4. The transcriptional regulator PRDM12 is critical for Pomc expression in the mouse hypothalamus and controlling food intake, adiposity, and body weight
5. Lorcaserin improves glycemic control via a melanocortin neurocircuit
6. Reprogramming the body weight set point by a reciprocal interaction of hypothalamic leptin sensitivity and Pomc gene expression reverts extreme obesity
7. Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons
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