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Objectives: To assess the usefulness of a tool based on ICD-10 diagnostic codes to identify patients who consult an emergency department for adverse drug events (ADE)., Methods: Prospective observational study, in which patients discharged from an emergency department during May to August 2022 with a diagnosis coded with one of the 27 ICD-10 diagnoses considered as triggers were included. ADE confirmation was carried out by analyzing drugs prescribed prior to admission, and through a discussion among experts and a phone interview with patients after hospital discharge., Results: 1143 patients with trigger diagnoses were evaluated, of which 310 (27.1%) corresponded to patients whose emergency visit was attributed to an ADE. A 58.4% of ADE consultations were found with three diagnostic codes: K59.0-Constipation (n = 87; 28.1%), I16.9-Hypertensive Crisis (n = 72; 23.2%) and I95.1-Orthostatic hypotension (n = 22; 7.1%). The diagnoses with the highest degree of association with consultations attributed to ADE were E16.2-Hypoglycemia, unspecified (73.7%) and E11.65-Type 2 diabetes mellitus with hyperglycemia (71.4%), while diagnoses D62-Acute posthemorrhagic anemia and I74.3-Embolism and thrombosis of arteries of the lower limbs were not attributed to any case of ADE., Conclusions: The ICD-10 codes associated with trigger diagnoses are a useful tool to identify patients who consult the emergency services with ADE and could be used to apply secondary prevention programs to avoid new consultations to the health care system., Competing Interests: Conflicts of interest No conflicts of interest are declared., (Copyright © 2023 Sociedad Española de Farmacia Hospitalaria (S.E.F.H). Publicado por Elsevier España, S.L.U. All rights reserved.)

Objective: Deprescribing is considered one of the main strategies available for  preparing an individualized therapeutic plan in patients with multiple pathologies or complex chronic conditions. However, despite the practice has been in place for some years, there is a need for studies that support the achievement of satisfactory health outcomes, as well as tools that help implement deprescribing in routine clinical practice. The  bjective of this project is to analyze the impact of reducing polypharmacy,  through the LESS-CHRON deprescribing tool, on a population  of elderly polymedicated patients with multiple conditions., Method: This will be a quasi-experimental, pre-and-post intervention multicenter cohort study. The variables to be analyzed will be  divided into two large groups: those related to pharmacology and those related to health outcomes. They will be collected at baseline, at 3 and at 6-12  months. A first screening phase will be carried out to recruit candidate patients  and obtain information about the identified deprescribing  opportunities. The second phase will constitute the intervention phase, where  the LESS-CHRON tool will be applied and the actual deprescribing of the drugs  will be carried out., Discussion: LESS-CHRON has been proclaimed as a suitable deprescribing tool in clinical practice. Validation of LESS-CHRON will seek to show the results that can be achieved following the deprescribing of drugs,  in addition to demonstrating that the tool can reliably be used by clinicians in  their routine practice. On the other hand, the results of this project may  provide information leading to improving or adapting the tool itself, giving rise  to a second generation of more efficient version., (Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.)

Objective: To describe the current situation regarding the specialized pharmaceutical service provision in nursing homes in Spain,  from a healthcare perspective reflecting activity, care and services  provided., Method: Observational, cross-sectional, multicenter study conducted between February-June 2018 through a survey aimed at all  Hospital Pharmacy Units in Spain. Once the initial version was assessed  by twelve evaluators whose healthcare assistance work were related to  nursing homes, an electronic form was designed, consisting on 10  dimensions and 66 questions. A piloting was carried out by six nursing  homes pharmacists. The results were analyzed descriptively. Results: The overall response rate was 29.7% (113 out of 380). Out of  all studied hospital pharmacy units, 46.0% (n = 52) served nursing  homes (9 as Nursing Homes Pharmacy Department) whose  characteristics defined a profile of pharmacy unit at hospital, public  ownership, consolidation in this activity, with great variability in the  number of centers and patients to be attended by service, and with the  pharmacist's partial dedication. In 51.3% of cases, nursing homes  professionals were represented at pharmacy and therapeutic  committees, while 38.5% were from pharmacy services who  participated in the selection of medical devices. Also, 67.4% performed  an integral management of the therapy. The study has also shown that  34.6% counted on assisted electronic prescription, while 88.5%  performed a pharmaceutical validation of the prescription prior to  dispensing, which in 71.2% of cases consisted of individualized unit  doses. It was found that 42.3% performed a third-level treatment  comprehensive review, and 25.0% participated in the interdisciplinary  nutritional assessment. It also showed that 34.6% actively participated  in either comprehensive geriatric assessment, or clinical cases in  interdisciplinary teams, and 46.2% counted on programs for the safe  use of medicines., Conclusions: The specialized pharmaceutical care at nursing homes is a reality, although it presents important differences in essential  aspects for the quality of the assistance provided. It is necessary to go  in-depth on the care model to be developed, as well as having a greater  involvement of pharmacy services to achieve a comprehensive and  person-centered care., (Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.)