62 results on '"Gallardo M"'
Search Results
2. Actitud ante el sida de los estudiantes de enfermería de la Escuela Puerta de Hierro (Universidad Autónoma de Madrid)
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Pilar Serrano-Gallardo, M. and Giménez-Maroto, Ana M. <ce:sup loc='post">a</ce:sup>
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- 2006
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3. Vacunación frente a la gripe en trabajadores de un hospital general. Estrategias para incrementar su cobertura
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García de Codes Ilario, Aurelia, Arrazola Martínez, M. del Pilar, Ramón de Juanes Pardo, José, Sanz Gallardo, M. Inmaculada, Jaén Herreros, Felisa, and Lago López, Emilia
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- 2004
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4. Aportaciones metodológicas a la cohesión de equipos sometidos a desgaste emocional
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Barrutia Arregi, I., Beitia, L., González, B., Leza, N., Sagasta, A., Martínez, S., Acaute, A., Calvo, J., Bacete, R., Garzia, N., Toresano, M., and Gallardo, M.
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- 2003
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5. Hipertensión arterial y menopausia reciente: estudio comparativo de dos fármacos hipotensores
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González-Portal, C., Baños Gallardo, M., Torres Lacalle, A., and Forascepi Roza, R.
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- 2000
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6. Depleción del ácido desoxirribonucleico mitocondrial y mutaciones de POLG en un paciente con neuropatía sensorial atáxica, disartria y oftalmoplejía
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Posada, Ignacio J., Gallardo, M. Esther, Domínguez, Cristina, Rivera, Henry, Arenas, Joaquín, Martín, Miguel A., Garesse, Rafael, Bornstein, Belén, Posada, Ignacio J., Gallardo, M. Esther, Domínguez, Cristina, Rivera, Henry, Arenas, Joaquín, Martín, Miguel A., Garesse, Rafael, and Bornstein, Belén
- Abstract
[Fundamento y objetivo]: Un amplio espectro de enfermedades mitocondriales está producido por mutaciones de POLG y se caracterizan por una alteración en la integridad del genoma mitocondrial. La oftalmoplejía progresiva externa suele ser el marcador clínico en los casos de deleciones múltiples, pero no lo es en aquellas enfermedades que cursan con depleción del ácido desoxirribonucleico mitocondrial (ADNmt). En este trabajo presentamos un paciente con la tríada clínica que define el síndrome de neuropatía sensorial atáxica, disartria y oftalmoplejía, las mutaciones del gen POLG y la presencia inusual de una marcada disminución en el contenido del ADNmt en el músculo esquelético. [Paciente y método]: El paciente presentó un cuadro clínico caracterizado por neuropatía sensorial atáxica, disartria y oftalmoplejía. El diagnóstico se realizó mediante estudios histológicos y análisis molecular del ADNmt y del gen POLG. [Resultados]: La biopsia del nervio sural detectó una pérdida intensa de las fibras nerviosas mielinizadas gruesas. El estudio molecular reveló mutaciones en el gen POLG, así como deleciones múltiples y una marcada depleción del genoma mitocondrial. [Conclusiones]: Los pacientes con síndromes atáxicos de origen mitocondrial presentan fenotipos mitocondriales moleculares diferentes, por lo que se aconseja la búsqueda de mutaciones del gen POLG en todos ellos, independientemente de la anomalía que presenten en el genoma mitocondrial.
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- 2010
7. Genomic cloning and characterization of the human homeobox gene SIX6 reveals a cluster of SIX genes in chromosome 14 and associates SIX6 hemizygosity with bilateral anophthalmia and pituitary anomalies
- Author
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Gallardo, M. Esther, Lopez-Rios, Javier, Fernaud-Espinosa, Isabel, Granadino, Begoña, Sanz, Raúl, Ramos, Carmen, Ayuso, Carmen, Seller, Mary J., Brunner, Han G., Bovolenta, Paola, Rodríguez de Córdoba, Santiago, Gallardo, M. Esther, Lopez-Rios, Javier, Fernaud-Espinosa, Isabel, Granadino, Begoña, Sanz, Raúl, Ramos, Carmen, Ayuso, Carmen, Seller, Mary J., Brunner, Han G., Bovolenta, Paola, and Rodríguez de Córdoba, Santiago
- Abstract
The Drosophila gene sine oculis (so), a nuclear homeoprotein that is required for eye development, has several homologues in vertebrates (the SIX gene family). Among them, SIX3 is considered to be the functional orthologue of so because it is strongly expressed in the developing eye. However, embryonic SIX3 expression is not limited to the eye field, and SIX3 has been found to be mutated in some patients with holoprosencephaly type 2 (HPE2), suggesting that SIX3 has wide implications in head development. We report here the cloning and characterization of SIX6, a novel human SIX gene that is the homologue of the chick Six6(Optx2) gene. SIX6 is closely related to SIX3 and is expressed in the developing and adult human retina. Data from chick and mouse suggest that the human SIX6 gene is also expressed in the hypothalamic and the pituitary regions. SIX6 spans 2567 bp of genomic DNA and is split in two exons that are transcribed into a 1393-nucleotide-long mRNA. Chromosomal mapping of SIX6 revealed that it is closely linked to SIX1 and SIX4 in human chromosome 14q22.3-q23, which provides clues about the origin and evolution of the vertebrate SIX family. Recently three independent reports have associated interstitial deletions at 14q22.3-q23 with bilateral anophthalmia and pituitary anomalies. Genomic analyses of one of these cases demonstrated SIX6 hemizygosity, strongly suggesting that SIX6 haploinsufficiency is responsible for these developmental disorders.
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- 1999
8. Valoración de la fiabilidad externa de las publicaciones de dos revistas científicas durante el último quinquenio
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Pilar Serrano Gallardo, M., Ordobás Gavín, María, Fernández Rodríguez, Silvia, and Carlos Silva Ayçaguer, Luis
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- 2003
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9. Bronquiolitis obliterante con neumonia organizativa. descripcion de un caso
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Lobo Gallardo, M., Pueyo Bastida, A., Suárez Pinilla, F.J., Aguirre Dabán, M.<ce:sup loc='post">a</ce:sup> C., Conget López, F., and Morales Asín, J.
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- 1990
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10. Leiomiona de pulmon: a proposito de un caso
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Llobregat Poyan, N., Mentrida Rodríguez, J.M., González Aragoneses, F., Orusco Palomino, E., Pérez Gallardo, M., Folque Gómez, E., and Rábano Gutiérrez, A.
- Published
- 1988
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11. Mioblastoma de celulas granulosas de localizacion bronquial
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Gonzalez Aragoneses, F., Zapatero Gaviria, J., Mentrida Rodriguez, J.M., Llobregat Poyan, N., Orusco Palomino, E., Perez Gallardo, M., Folque Gomez, E., Monturiol Rodriguez, J.M., and Alvarez Fernandez, E.
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- 1987
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12. Timoma granulomatoso: Enfermedad de hodgkin del timo
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Gonzalez Aragoneses, F., Bellon Caneiro, J.M., Zapatero Gaviria, J., Baamonde Laborda, C., Orusco Palomino, E., Perez Gallardo, M., and Folque Gomez, E.
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- 1983
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13. Coriocarcinoma primitivo de pulmon. Presentacion de un caso y revision de la literatura
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Zapatero Gaviria, J., Bellon Caneiro, J., Baamonde Laborda, C., Gonzalez Aragoneses, F., Cubillo Marcos, J.M., Orusco Palomino, E., Perez Gallardo, M., Zapatero Dominguez, J., and Folque Gomez, E.
- Published
- 1983
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14. Quistes broncogenicos pulmonares. Presentacion de 4 casos
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González Aragoneses, F., Baamonde Laborda, C., Zapatero Renón, L., Orusco Palomino, E., Pérez Gallardo, M., and Folqué, E.
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- 1980
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15. Neumonía extrahospitalaria y empiema por Streptococcus viridans en un adulto sano
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Lobo Gallardo, M., Herrejón Silvestre, A., and Rodó Muñoz, M.
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- 1989
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16. Amiloidosis bronquial localizada
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Ancochea Bermúdez, J., López-Elzaurdia, C., Jiménez Ruíz, C., Aspa Marco, F.J., Lobo Gallardo, M., and González González, A.
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- 1988
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17. Hamartoma endobronquial: Descripción de un caso
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Sanz Sanz, P., Solano Reina, S., Lobo Gallardo, M., Ancochea Bermúdez, J., Aspa Marco, F., and Jiménez Ruiz, C.
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- 1988
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18. [Acceptance and intention to use of a physiological sensor shirt in health field in older patients].
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Ramírez-Martín A, Poveda Gómez F, Aranda-Gallardo M, Martin-Bautista E, Rivas Ruiz F, and García-Alegría JJ
- Abstract
Objectives: To assess the acceptance and intention to use physiological sensor shirt among older patients in healthcare, as well as to identify the factors that encourage a positive attitude towards its adoption., Methods: Cross-sectional study using questionnaires addressed to patients between 60 and 85years of age, administered via face-to-face interviews to determine intention to use a shirt with physiological sensors. The extended version of the Technology Acceptance Model (TAM) questionnaire was used in conjunction with administration of the quality of life and perceived stress scales., Results: Forty-eight patients participated in the study, 54.2% were male with a mean age of 70.5years. The mean scores for attitude towards use and intention to use were 3.9 (SD: 0.8) and 3.3 (SD: 0.8), respectively, out of a maximum of 5. The willingness to use the device was positive in 72.9% of patients The patients intending to use wearable technology (n=35) scored significantly higher than those unwilling to wear the shirt (n=13) on perceived ubiquity (P=.031), perceived ease of use (P=.002), and perceived utility (P=.007)., Conclusions: In a sample of independent older adults from the healthcare sector, a high willingness to use a shirt with physiological sensors was found. Through the TAM questionnaire, ubiquity, perceived ease of use, and perceived usefulness were identified as key factors predisposing its adoption., (Copyright © 2024 SEGG. Publicado por Elsevier España, S.L.U. All rights reserved.)
- Published
- 2024
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19. Case report: A rare case of cyclodialysis after cataract surgery managed exclusively with medical therapy.
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Romero-Titos A, Álvarez-Sánchez P, Hermoso Fernández FM, Muñoz de Escalona Rojas JE, González Gallardo MC, and Martínez Castillo R
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- Humans, Female, Aged, Microscopy, Acoustic, Cyclodialysis Clefts etiology, Ocular Hypotension etiology, Mydriatics therapeutic use, Tomography, Optical Coherence, Phacoemulsification, Postoperative Complications etiology
- Abstract
We present the case of a 68-year-old female who presented with a substantial cyclodialysis after phacoemulsification identified by anterior segment optical coherence tomography and ultrasound biomicroscopy. Gonioscopy is challenging because of its shallow anterior chamber. Due to lack of response to topical steroids and refusal by the patient for surgical treatment, topical steroids were tapered, and cycloplegic was initiated. After two weeks, the cyclodialysis cleft was closed on optical coherence tomography persisting residual subchoroidal fluid, topical treatment was mantained. Despite of this, visual acuity and hypotony were restored. Finally at 2 months visit subchoroidal fluid was reabsorbed and patient was discharged. Clinics should consider the possibility of cyclodialysis in cases of unjustified hypotony during postoperative period. In addition, we recommend performing anterior segment imaging which includes ultrasound biomicroscopy and optical coherence tomography, when the evaluation of angular structures is unfeasible. Finally, we propose medical management for severe cyclodialysis as the first option considering anti-inflammatory drugs could perpetrate the separation between scleral spur and ciliary muscle., (Copyright © 2024 Sociedad Española de Oftalmología. Published by Elsevier España, S.L.U. All rights reserved.)
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- 2024
- Full Text
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20. Andalusian Public Eye-Banks: a decade of continuous improvement.
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Rodríguez-Calvo-de-Mora M, Giménez-Almenara-Amo J, Mataix-Albert B, Arias-Alcalá M, García-Montesinos-Gutiérrez J, Rocha-de-Lossada C, Villalba-Montoro R, Díaz-Gallardo MS, Cuende N, and Álvarez-Márquez A
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- Humans, Retrospective Studies, Spain, Hospitals, Public statistics & numerical data, Tissue and Organ Procurement statistics & numerical data, Keratoplasty, Penetrating statistics & numerical data, Tissue Donors statistics & numerical data, Tissue Donors supply & distribution, Hospitals, Private statistics & numerical data, Corneal Transplantation statistics & numerical data, Eye Banks statistics & numerical data
- Abstract
Objectives: To show donation data, number of keratoplasties and the changes in transplant indications and techniques that occurred in Andalusia in the period from 2013 to 2022., Materials and Methods: The present work is a retrospective and descriptive study that included all keratoplasties performed between January 2013 and December 2022 in Andalusia, as well as the evolution of the cornea donation and transplant activity of the public and private hospitals pertaining to the waiting list management system of the Public Health System of Andalusia. Transplants performed in private centers with corneas from outside Andalusia were excluded., Results: Cornea donation activity in Andalusia in the decade 2013-2022 has experienced a growth of more than 126%, while overall transplant activity has increased by 157% in public hospitals. Penetrating keratoplasty has decreased from 83% in 2013 to 43% in 2022, while lamellar techniques have increased from 17% to 57% in this same period. Since 2018, more lamellar transplants are performed than penetrating transplants. Regarding indications, endothelial conditions already represent the first cause of transplantation. In 2022 alone, the public Andalusian Eye Banks evaluated 1,054 corneas and prepared 281 endothelial grafts., Conclusion: In the decade from 2013 to 2022 in Andalusia there has been an increase in donation activity and the number of keratoplasties. The public Eye Banks implementation in this period has played a key role in the widespread adoption of lamellar keratoplasty techniques and has enabled the transition to perform a greater number of lamellar keratoplasties compared to penetrating keratoplasty., (Copyright © 2024 Sociedad Española de Oftalmología. Published by Elsevier España, S.L.U. All rights reserved.)
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- 2024
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21. A multidisciplinary challenge: Therapy with phosphorus-32 for locally advanced pancreatic cancer.
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Peiró-Valgañón V, Guardiola-Arévalo A, López Fernández A, Llorente Herrero E, and Martín Fernández-Gallardo MT
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- Humans, Pancreas, Pancreatic Neoplasms, Pancreatic Neoplasms diagnostic imaging, Pancreatic Neoplasms drug therapy, Adenocarcinoma therapy, Adenocarcinoma drug therapy
- Abstract
Pancreatic cancer is a disease with a poor prognosis, and overall survival has improved the least in the last 40 years of all cancers. Locally advanced pancreatic adenocarcinoma, without distant metastasis but with limiting vascular involvement, constitutes almost one third of these patients. This group is the focus of most research efforts to introduce treatments to increase surgical salvage rates and/or survival, with two main objectives: local control and prevention of systemic progression. Intratumoural treatment with phosphorus-32 microparticles, guided by echoendoscopy and combined with standard chemotherapy may have significant and clinically relevant benefits in these patients, and therefore a valuable treatment option in a disease where there is an urgent need to develop new therapies to help improve outcomes., (Copyright © 2023 Sociedad Española de Medicina Nuclear e Imagen Molecular. Published by Elsevier España, S.L.U. All rights reserved.)
- Published
- 2023
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22. [Comparison between patients attended in the emergency department of a tertiary hospital in Madrid in the first and second wave of coronavirus SARS-COV-2 pandemic].
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Martín Espín I, Plata Gallardo M, de Miguel Cáceres C, Bueno Barriocanal M, and de Ceano-Vivas la Calle M
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- 2021
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23. Usefulness of chest X-rays for evaluating prognosis in patients with COVID-19.
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Adarve Castro A, Díaz Antonio T, Cuartero Martínez E, García Gallardo MM, Bermá Gascón ML, and Domínguez Pinos D
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- Aged, Humans, Prognosis, Retrospective Studies, SARS-CoV-2, X-Rays, COVID-19
- Abstract
Background and Aims: The pandemia caused by SARS-CoV-2 (COVID-19) has been a diagnostic challenge in which chest X-rays have had a key role. This study aimed to determine whether the Radiological Scale for Evaluating Hospital Admission (RSEHA) applied to chest X-rays of patients with COVID-19 when they present at the emergency department is related with the severity of COVID-19 in terms of the need for admission to the hospital, the need for admission to the intensive care unit (ICU), and/or mortality., Material and Methods: This retrospective study included 292 patients with COVID-19 who presented at the emergency department between March 16, 2020 and April 30, 2020. To standardize the radiologic patterns, we used the RSEHA, categorizing the radiologic pattern as mild, moderate, or severe. We analyzed the relationship between radiologic severity according to the RSEHA with the need for admission to the hospital, admission to the ICU, and mortality., Results: Hospital admission was necessary in 91.4% of the patients. The RSEHA was significantly associated with the need for hospital admission (p = 0.03) and with the need for ICU admission (p < 0.001). A total of 51 (17.5%) patients died; of these, 57% had the severe pattern on the RSEHA. When we analyzed mortality by grouping patients according to their results on the RSEHA and their age range, the percentage of patients who died increased after age 70 years in patients classified as moderate or severe on the RSEHA., Conclusions: Chest X-rays in patients with COVID-19 obtained in the emergency department are useful for determining the prognosis in terms of admission to the hospital, admission to the ICU, and mortality; radiologic patterns categorized as severe on the RSEHA are associated with greater mortality and admission to the ICU., (Copyright © 2021 SERAM. Published by Elsevier España, S.L.U. All rights reserved.)
- Published
- 2021
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24. In reply to "Management of accidental hypothermia: Narrative review".
- Author
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Chavala MLA, Gallardo MA, Martínez IS, and Bayego ES
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- Humans, Hypothermia
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- 2020
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25. Management of accidental hypothermia: A narrative review.
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Avellanas Chavala ML, Ayala Gallardo M, Soteras Martínez Í, and Subirats Bayego E
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- Avalanches, Biomarkers blood, Body Temperature, Cardiopulmonary Resuscitation standards, Cold Temperature adverse effects, Electric Countershock, Extracorporeal Membrane Oxygenation methods, Fluid Therapy methods, Hospitalization, Humans, Hypothermia complications, Hypothermia diagnosis, Immersion adverse effects, Oxygen Consumption, Potassium blood, Cardiopulmonary Resuscitation methods, Emergency Medical Services, Hypothermia therapy, Out-of-Hospital Cardiac Arrest therapy, Rewarming methods
- Abstract
A narrative review is presented on the diagnosis, treatment and management of accidental hypothermia. Although all these processes form a continuum, for descriptive purposes in this manuscript the recommendations are organized into the prehospital and in-hospital settings. At prehospital level, it is advised to: a) perform high-quality cardiopulmonary resuscitation for cardiac arrest patients, regardless of body temperature; b) establish measures to minimize further cooling; c) initiate rewarming; d) prevent rescue collapse and continued cooling (afterdrop); and (e) select the appropriate hospital based on the clinical and hemodynamic situation of the patient. Extracorporeal life support has revolutionized rewarming of the hemodynamically unstable victim or patients suffering cardiac arrest, with survival rates of up to 100%. The new evidences indicate that the management of accidental hypothermia has evolved favorably, with substantial improvement of the final outcomes., (Copyright © 2018 Elsevier España, S.L.U. y SEMICYUC. All rights reserved.)
- Published
- 2019
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26. Cross-cultural adaptation of the STRATIFY tool in detecting and predicting risk of falling.
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Enríquez de Luna-Rodríguez M, Aranda-Gallardo M, Canca-Sánchez JC, Vazquez-Blanco MJ, Moya-Suárez AB, and Morales-Asencio JM
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- Cross-Sectional Studies, Cultural Characteristics, Homes for the Aged, Hospitals, Humans, Nursing Homes, Translations, Accidental Falls statistics & numerical data, Diagnostic Self Evaluation, Risk Assessment
- Abstract
Aims: To adapt to Spanish language the STRATIFY tool for clinical use in the Spanish-speaking World., Method: A multicenter, 2 care settings cross-sectional study cultural adaptation study in acute care hospitals and nursing homes was performed in Andalusia during 2014. The adaptation process was divided into 4 stages: translation, back-translation, equivalence between the 2 back-translations and piloting of the Spanish version, thus obtaining the final version. The validity of appearance, content validity and the time required to complete the scale were taken into account. For analysis, the median, central tendency and dispersion of scores, the interquartile range, and the interquartile deviation for the possible variability in responses it was calculated., Results: Content validity measured by content validity index reached a profit of 1. For the validity aspect the clarity and comprehensibility of the questions were taken into account. Of the 5 questions of the instrument, 2 had a small disagreement solved with the introduction of an explanatory phrase to achieve conceptual equivalence. Median both questions were equal or superior to 5. The average time for completion of the scale was less than 3 minutes., Conclusion: The process of adaptation to Spanish of STRATIFY has led to a semantic version and culturally equivalent to the original for easy filling and understanding for use in the Spanish-speaking world., (Copyright © 2016 Elsevier España, S.L.U. All rights reserved.)
- Published
- 2017
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27. [Donors deceased according to cardiocirculatory criteria (Maastricht 3) with livers valid for transplantation].
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Daga-Ruiz D, Frutos-Sanz MA, Segura-González F, Lebrón-Gallardo M, Pérez-Vacas J, and Muñoz-Muñoz JL
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- Brain Ischemia complications, Carcinoma, Hepatocellular surgery, Cerebral Hemorrhage complications, Female, Glucose, Heart Arrest diagnosis, Heart Arrest etiology, Humans, Liver Cirrhosis, Alcoholic surgery, Liver Neoplasms surgery, Male, Mannitol, Middle Aged, Organ Preservation methods, Organ Preservation Solutions, Potassium Chloride, Practice Guidelines as Topic, Procaine, Treatment Outcome, Death, Liver Transplantation, Tissue Donors supply & distribution, Tissue and Organ Harvesting methods, Tissue and Organ Procurement standards
- Published
- 2015
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28. [Evaluation of a functional plan for caregivers in hospital].
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Quiñoz-Gallardo MD, Vellido-González C, Rivas-Campos A, Martín-Berrido M, González-Guerrero L, Vellido-González D, Nieto-Poyato RM, and Corral-Rubio MC
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- Humans, Surveys and Questionnaires, Caregivers organization & administration, Hospitalization
- Abstract
Background: The care of dependent persons has increased, as such that healthcare reforms are taking caregivers into account. A functional plan in hospitalization was developed for caregivers, and his study aims to investigate its implementation, identifying the strengths and weaknesses that promote changes between the formal and informal system., Methods: A qualitative study was designed, using nursing professionals and caregivers identified in the hospital as subjects. A focus group technique was used with 8 people selected for each segment. Two scripts were developed with questions on the evaluation criteria included in the plan: identification/recruitment, reception, rest, diet, health care, information/health education, management and implementation of the plan and other proposals. The data were collected during May 2011., Results: Difficulties were encountered in identifying caregivers, as an initial evaluation was not made. As regards the reception, in some cases the information brochure was not given. Rest was not possible as the caregivers did not want to move away from the patient. Diet was the main cause of the conflict, highlighting the lack of health education to continue in home care. Circuits of preferential care in emergency were positively valuated. Nurses consider the plan as an extra task., Conclusions: The strengths and weaknesses identified should enable improvements to be made in the implementation of the plan, in order to achieve changes in specific aspects such as information/education, health, rest and diet of the caregivers. We emphasize the need to enhance the model change., (Copyright © 2013 Elsevier España, S.L. All rights reserved.)
- Published
- 2013
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29. [General planning for the maintenance of the organ donor].
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Seller Pérez G, Herrera-Gutiérrez ME, Lebrón-Gallardo M, and Quesada-García G
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- Hemodynamics, Humans, Practice Guidelines as Topic, Preoperative Care, Water-Electrolyte Balance, Tissue Donors, Tissue and Organ Procurement standards
- Published
- 2009
- Full Text
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30. [Liver transplantation: influence of donor-related factors].
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Seller-Pérez G, Herrera-Gutiérrez ME, Lebrón-Gallardo M, Moreno-Quintana J, Banderas-Bravo E, and Quesada-García G
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- Adult, Cohort Studies, Female, Humans, Liver Transplantation adverse effects, Male, Middle Aged, Postoperative Complications epidemiology, Postoperative Complications etiology, Retrospective Studies, Liver Transplantation physiology, Tissue Donors
- Abstract
Objective: To detect donor characteristics related to graft function after orthotopic liver transplantation (OLT)., Design: Retrospective cohort study., Context: Polyvalent intensive care unit., Patients: 145 liver transplant recipients and their respective donors., Interventions: None., Main Variables of Interest: In donors: age, hypernatremia, and infection. In recipients: reperfusion syndrome, coagulopathy, infection, ARDS, shock, kidney failure, primary graft dysfunction, and mortality., Results: 71.7% of recipients were male. Mean recipient age was 54.5 +/- 9.9 years; 66.2% of patients were classified as Child B and and 19.3% as Child C. The mean model for end-stage liver disease (MELD) score was 14.6 +/- 4.8 and the mean APACHE II score was 17.3 +/- 4.9. A total of 64.1% of the donors were male. Mean donor age was 42.3 +/- 16.3 years, and mean APACHE II score was 22.3 +/- 5.8. Donor age > 65 years was associated to higher recipient aspartate aminotransferase (AST) levels but not to increased complications or mortality. No other donor factors (including age, sex, serum sodium, severity level, transfusions, hemodynamic alterations, renal dysfunction, or infection) were associated to evolution or prognosis. Infection was diagnosed in 18 recipients (12.4%) in the postoperative period; the incidence of infection in recipients that received an organ from infected donors was not different from those that received an organ from an uninfected donor (14.6% versus 11.5%; p > 0.05)., Conclusions: We detected no donor characteristics related to graft function or the appearance of complications in recipients during the immediate postoperative period. Donor age > 65 years and documented but appropriately treated bacteremia posed no risk for the viability of the liver after transplantation.
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- 2008
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31. [A case of linear atrophoderma of Moulin].
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López N, Gallardo MA, Mendiola M, Bosch R, and Herrera E
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- Adolescent, Arm, Humans, Male, Hyperpigmentation pathology
- Published
- 2008
32. [Safety and efficacy of the MARS therapy applied by continuous renal replacement therapy (CRRT) monitors].
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Herrera-Gutiérrez ME, Seller-Pérez G, Lebrón-Gallardo M, Jiménez-Pérez M, Moreno-López JM, and Muñoz-López A
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- Adsorption, Adult, Female, Humans, Male, Middle Aged, Monitoring, Physiologic, Prospective Studies, Safety, Liver Failure therapy, Renal Replacement Therapy methods
- Abstract
Objective: Analyze the utility and safety of MARS therapy applied with the CRRT monitor., Design: Prospective study of cohorts., Scope: Polyvalent ICU in tertiary university hospital with hepatic transplantation program., Patients: Thirty one patients: 9 (22.6%) with acute liver failure (ALF) (1 hepatic surgery, 1 primary graft failure, 7 other causes) and 22 (71%) with acute-on-chronic failure (AoCLF)., Interventions: For the treatment, the patients with ALF are maintained in the ICU but those with AoCLF are admitted for the performance of the different sessions, that are programmed for a duration of at least 15 hours in AoCLF and in ALF are maintained continuously, changing the circuit every 24 hours., Variables of Interest: Metabolic control and complications registered in 75 sessions on 31 patients., Results: Urea decrease was 33.5 (29-38%), creatinine 36 (31-41%), total bilirubin 29 (25-33%) and direct bilirubin 34 (30-38%). Clearance was slower, but sustained, after the first 4 hours of each session both for urea (p<0.001) as well as for bilirubin (p<0.05). The hemodynamic parameters improved and the hematological ones were not altered. We detected decrease in platelets (131 to 120x109/L, p<0.01). In 95 of the sessions in which heparin was used and in 6% where epoprostenol was used, we observed mild bleeding. We cultured albumin of the circuit at the end of the session in 50 occasions and only obtained growth in 3 cases (6%) (2 Staphylococcus epidermidis, 1 S. haemolyticus) without signs of contamination in the patients., Conclusions: The MARS system applied by CRRT monitors provide adequate bilirubin clearance percentages and is safe, even in serious patients. Prolongation of the duration of the sessions was not accompanied by an increase in the risk of infection secondary to the albumin contamination.
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- 2007
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33. [Use of isolated epoprostenol or associated to heparin for the maintenance of the patency of the continuous renal replacement technical circuits].
- Author
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Herrera-Gutiérrez ME, Seller-Pérez G, Lebrón-Gallardo M, De La Cruz-Cortés JP, and González-Correa JA
- Subjects
- Acute Kidney Injury therapy, Anticoagulants administration & dosage, Anticoagulants adverse effects, Epoprostenol administration & dosage, Epoprostenol adverse effects, Female, Hemodiafiltration methods, Hemorrhage chemically induced, Heparin administration & dosage, Heparin adverse effects, Humans, Intensive Care Units, Male, Middle Aged, Prospective Studies, Anticoagulants therapeutic use, Catheterization, Peripheral methods, Epoprostenol therapeutic use, Femoral Vein physiology, Hemodiafiltration instrumentation, Heparin therapeutic use, Vascular Patency drug effects
- Abstract
Objective: At present, there is no consensus on the best anticoagulant regimen for the maintenance of extrarenal clearance circuits (RRTC). We present our experience with the isolated use of epoprostenol in patients at risk of bleeding or associated to non-fractionated heparin (nFH) in patients with problems of early coagulation of the filters., Design: Prospective study of cohorts on all the RRTC filters used in our service since 1994., Scope: Forty-two-bed polyvalent ICU in a tertiary hospital., Interventions: Anticoagulation was administered in prefilter perfusion, at doses of 5-7 U/kg/hour for nFH or 4-5 ng/kg/min for epoprostenol. The combined use was done with equal doses of epoprostenol and nFH at 2,5 U/kg/hour. VARIABLES OF MAIN INTEREST: We analyzed the duration of each filter, reason for removing the filter, existence of coagulopathy, platelet count, appearance of bleeding, anticoagulant used and dose., Results: We analyzed the use of 2,322 filters (66,957 hours) in 389 patients, 54% of whom had a clot. nFH was used in 74% of the filters for a median of 39 hours (interquartile range: 19-75), epoprostenol in 6% for 32 hours (interquartile range: 17-48) and combined therapy in 4% for 27 hours (interquartile range: 19-41). In the epoprostenol group, we detected a decrease in blood pressure in only two filters that became normal when the dose was decreased. The filters that were initially anticoagulated with nFH had a 14-hour survival as a median versus 27 hours in combined therapy (p < 0.001). In absence of coagulopathy or thrombopenia, we observed mild bleeding in 8%, moderate in 1% and serious in 1% in the 1,170 filters treated with nFH. We only observed mild bleeding in 3% in 66 filters with epoprostenol., Conclusions: Isolated epoprostenol in patients at risk of bleeding provided a similar duration of the filters to nFH, decreasing the risk of bleeding. The use of epoprostenol plus low dose nFH significantly increases their duration in patients with early coagulation.
- Published
- 2006
- Full Text
- View/download PDF
34. [Serum C-reactive protein as a marker of outcome and infection in critical care patients].
- Author
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Seller-Pérez G, Herrera-Gutiérrez ME, Lebrón-Gallardo M, de Toro-Peinado I, Martín-Hita L, and Porras-Ballesteros JA
- Subjects
- APACHE, Adult, Aged, Female, Humans, Intensive Care Units, Male, Middle Aged, Prospective Studies, Respiration, Artificial, Sepsis physiopathology, C-Reactive Protein metabolism, Critical Illness mortality, Sepsis blood
- Abstract
Background and Objective: C-reactive protein (CRP) has been considered a marker for infection and an aid for diagnosing sepsis. We analyze the relation of CRP to infection and outcome in intensive care units (ICU) patients., Patients and Method: Prospective study on 77 ventilated patients. Expected short ICU stay or (suspected or confirmed) infection at admission were excluding criteria. 55 admissions after elective surgery were the controls. CRP measurement the first (CRP-1), third (CRP-3) and sixth (CRP-6) day of stay. APACHE II (Acute Physiology Score and Chronic Health Evaluation), SOFA (Sepsis-related Organ Failure Assessment), shock, respiratory or renal failure, leucocytes, platelets and albumin were registered. Follow-up until day 9 for infection and ICU discharge for outcome., Results: CRP-1 in controls was 5.3 (3.9) mg/l and cases 67.8 (77.4) (p < 0.001). Shock on admission was related to CRP-1: patients in shock had higher CRP-1 levels (118.6 [82.8] vs 62.8 [75.6]; p = 0.06). 40.25% of cases developed infection, and CRP-1 levels were higher in this patients (88.8 [93.9] vs 53.8 [60.9]; p < 0.05). ROC area under curve was 0.6 with a sensibility of 23% and a specificity of 89% for a level of CRP-1 > 100. Mortality was 23.4% in cases and 1.8% in controls. Age, shock, APACHE II and SOFA were related to mortality, but CRP-1 did not. ROC area under curve for CRP-1 as mortality predictor in all patients was 0.62 (0.76 for APACHE II and 0.77 for SOFA) but only in cases was of 0.49 (0.69 for APACHE II and 0.67 for SOFA)., Conclusions: CRP level on admission is an useful marker for early infection but not for outcome in critically ill patients admited to the ICU.
- Published
- 2005
- Full Text
- View/download PDF
35. [Influenza vaccination in healthcare workers. Strategies to achieve compliance in a general hospital].
- Author
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García de Codes Ilario A, Arrazola Martínez Mdel P, de Juanes Pardo JR, Sanz Gallardo MI, Jaén Herreros F, and Lago López E
- Subjects
- Adult, Female, Hospitals, General, Humans, Male, Middle Aged, Seasons, Spain, Health Personnel statistics & numerical data, Infectious Disease Transmission, Professional-to-Patient prevention & control, Influenza Vaccines administration & dosage, Influenza, Human prevention & control, Vaccination statistics & numerical data
- Abstract
Background and Objective: Since healthcare workers can transmit the influenza virus to high risk patients, they should be vaccinated prior to the influenza season. In this study we describe the influenza vaccination coverage in healthcare workers in a general hospital and study its evolution over the last years., Subjects and Method: Descriptive epidemiological study to determine the anti-influenza vaccination coverage in healthcare workers in a hospital during 2002-2003 and 2003-2004 seasons. The variables studied in each season were sex, age and professional category., Results: During each of the campaigns, 1,215 and 2,287 workers were vaccinated. The vaccination coverage increased significantly (p < 0.01) (20.2% in 2002-2003 and 38% in 2003-2004). Men were vaccinated more than women although the coverage increase was significant in both sexes (p < 0.01). During the 2002-2003 season, workers older than 50 years (24.4%) had the greatest coverage, while during 2003-2004 those older than 31 years (48.7%) were the ones with more coverage. By professional categories, the medical staff (33.8% in 2002-2003 and 59.9% in 2003-2004) had a greater vaccination acceptance. The coverage increase during these two years was significant in all healthcare workers (p < 0.01)., Conclusions: A significant increase in the vaccination coverage has been observed during the two seasons studied. This fact can be related to the changes introduced in the informative strategies and the performance of more active vaccination campaigns which connect vaccination to employment areas.
- Published
- 2004
- Full Text
- View/download PDF
36. [Postoperative complications of liver transplantation: relationship with mortality].
- Author
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Seller-Pérez G, Herrera-Gutiérrez ME, Aragonés-Manzanares R, Muñoz-López A, Lebrón-Gallardo M, and González-Correa JA
- Subjects
- Cohort Studies, Humans, Intensive Care Units, Multivariate Analysis, Prospective Studies, Risk Factors, Survival Rate, Treatment Outcome, Liver Transplantation adverse effects, Liver Transplantation mortality, Postoperative Complications
- Abstract
Background and Objective: Liver transplant is an effective procedure for fulminant hepatitis or chronic liver disease and offers an adequate quality of life. However, even though it is a consolidated treatment, patients can develop serious complications in the immediate postoperative course., Patients and Method: Prospective observational study of 131 patients admitted in our intensive care unit after liver transplant surgery. We studied variables related with the development of complications and their relation to outcome., Results: Intensive care unit mortality was 11.5%. Median stay was 4 days. 90% of patients presented 2 or more complications. Hyperglycemia, thrombocytopenia and hypothermia were the most frequent complications but they were not related with mortality. Less frequent but related to outcome complications were acute renal failure (23.6% mortality vs. 1.3%; p < 0.01), ADRS (63.6% vs 6.7%; p < 0,01), low cardiac output (71.4% vs 4.3%; p < 0.01), > or = 2 vasoactive drugs (61.9% vs 1.8%; p < 0.01), encephalopathy (37.5% vs 9.8%; p < 0.05), pneumonia (80% vs 8%; p < 0.01) and hemorrhage (29.4% vs 8.8%; p < 0.05). Graph ischemia, coagulopathy, reperfusion syndrome and use of blood derivatives during surgery were factors related with the development of complications and mortality. Multivariate analysis showed a relationship with mortality and low cardiac output, number of vasoactive drugs and total time of graft ischemia., Conclusions: Complications during the postoperative course of liver transplant are frequent but most of them have no effect on prognosis. The negative effect of severe complications should be limited by optimizing the hemodynamic support in these patients and minimizing ischemia of transplanted organs.
- Published
- 2004
- Full Text
- View/download PDF
37. [Use of albumin dialysis with the MARS device to treat a case acute liver failure after partial hepatic resection].
- Author
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Herrera Gutiérrez ME, Seller Pérez G, Lebrón Gallardo M, and Quesada García G
- Subjects
- Albumins, Humans, Liver pathology, Liver Failure, Acute etiology, Male, Middle Aged, Postoperative Complications therapy, Treatment Outcome, Digestive System Surgical Procedures adverse effects, Liver surgery, Liver Failure, Acute therapy, Renal Dialysis instrumentation, Renal Dialysis methods
- Published
- 2004
- Full Text
- View/download PDF
38. [Sexual behaviour and use of condoms by adolescents in our environment].
- Author
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Mesa Gallardo MI, Barella Balboa JL, and Cobeña Manzorro M
- Subjects
- Adolescent, Adult, Cross-Sectional Studies, Female, Humans, Male, Condoms statistics & numerical data, Sexual Behavior
- Abstract
Objective: To identify sexual behaviour in adolescents., Design: Transversal, descriptive study, by means of an anonymous structured questionnaire., Setting: Urban secondary school., Participants: Simple random sample of 84 students (4th year of ESO--c. 15/16 years old)., Main Measurements: Personal details, sexual practices, use of condoms., Results: 61.9% were girls. Average age was 16.4 (95% CI, 16.2-16.6). They had a girl/boy-friend or casual partner (33.7%) and stable partner (60.7%). 82.2% had total or sufficient trust. Boys' first masturbation was between 14 and 16 (46.8%). 100% had done so by the age of 16. 72.3% of girls had never masturbated at this age (P<.001).Boys' first kiss on the lips occurred between 14 and 16 (46.8%); 100% had done so by 16. 60.7% of girls had done so between 14 and 16, and 92.2% by 16.30.1% of boys had had their first experience of coitus by the age of the questionnaire, whereas 22.5% of girls had. Both sexes used a condom on 71.4% of occasions.38.1% had sex with penetration, 46.2% masturbated. 22.2% had had 2 sexual partners, 8.9% had had 3, and 40.0% had had 4 or more. Condoms were used in 83.3% of relationships with penetration., Conclusions: This is a sexually active population, susceptible to sexually transmitted diseases (STD) and unwanted pregnancies, as it does not use condoms in every relationship involving penetration. Health education activities need to be encouraged.
- Published
- 2004
- Full Text
- View/download PDF
39. [Evaluation of external reliability between two scientific journal publications in the last five years].
- Author
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Serrano Gallardo MP, Ordobás Gavín M, Fernández Rodríguez S, and Silva Ayçaguer LC
- Subjects
- Bibliometrics, Reproducibility of Results, Retrospective Studies, Periodicals as Topic, Publishing standards
- Published
- 2003
40. [Contribution of the microbiology laboratory to epidemiologic surveillance].
- Author
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Román E, Valencia R, Fernández-Merino JC, and Gallardo MV
- Subjects
- Diagnosis-Related Groups, Humans, Medical Records Systems, Computerized, Spain, Disease Notification, Laboratories, Microbiology, Population Surveillance
- Published
- 2003
- Full Text
- View/download PDF
41. [Endoscopic dilatation of caustic esophageal strictures].
- Author
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López Vallejos P, García Sánchez MV, Naranjo Rodríguez A, Gálvez Calderón C, Hervás Molina A, Chicano Gallardo M, and Miño Fugarolas G
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Burns, Chemical etiology, Child, Female, Humans, Male, Middle Aged, Retrospective Studies, Treatment Outcome, Alkalies adverse effects, Burns, Chemical therapy, Catheterization methods, Esophageal Stenosis chemically induced, Esophageal Stenosis therapy, Esophagoscopy methods
- Abstract
Objective: To evaluate the results of endoscopic dilatation in caustic esophageal strictures and to analyze the factors associated with a favorable response., Patients and Method: We performed a retrospective study of 33 patients who underwent dilatation with Savary bougie between 1989 and 2001. Response to initial dilatation and outcome during follow-up were analyzed., Results: The mean age was 50 years (8-83) and 58% were women. Intake was accidental in 29 (88%). In all patients, the caustic substance ingested was alkali. Dilatation was started in the acute phase in 12 patients (36%) and 13 presented inflammatory phenomena adjacent to the stenosis. During initial dilatation, 2 1.6 sessions (2-18) were performed and a favorable response was obtained in 18 patients (54%). At the end of follow-up, 68% of the patients presented satisfactory health status. The comparative study revealed that statistically significant variables for a favorable response to treatment were: accidental alkali intake, instauration of treatment in the chronic phase, absence of inflammatory phenomena, and a small number of initial dilatation sessions., Conclusions: In our series, more than half the patients with esophageal stenosis due to intake of corrosive alkalis showed a favorable initial response. In these patients with acute-phase stenosis who required a greater number of initial dilatation sessions, endoscopic therapy was less effective.
- Published
- 2003
- Full Text
- View/download PDF
42. [Efficacy of fecal detection of Helicobacter pylori with the HpSA technique in patients with upper digestive hemorrhage].
- Author
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López Peñas D, Naranjo Rodríguez A, Muñoz Molinero J, Rodríguez López F, Gálvez Calderón C, Chicano Gallardo M, López Rubio F, and Miño Fugarolas G
- Subjects
- Adult, Aged, Aged, 80 and over, Antigens, Bacterial analysis, Feces chemistry, Female, Helicobacter pylori immunology, Humans, Male, Middle Aged, Predictive Value of Tests, Prospective Studies, Sensitivity and Specificity, Feces microbiology, Gastrointestinal Hemorrhage microbiology, Helicobacter pylori isolation & purification
- Abstract
Background: The rapid urease test is the most commonly used test in the diagnosis of Helicobacter pylori infection in patients with upper gastrointestinal hemorrhage. However, some studies have suggested that results of this test are frequently false negative when blood is present. An effective new enzyme immunoassay for determining H. pylori antigens in stools has recently begun to be used., Aim: To determine the efficacy of the H. pylori stool antigen test (HpSAT) in patients with upper gastrointestinal hemorrhage., Patients and Methods: Thirty-two patients with upper gastrointestinal hemorrhage were prospectively studied from November 1998 to April 1999. In all patients the following tests were performed in the first 72 hours after onset of bleeding and 24 hours after hospital admission: upper gastrointestinal endoscopy, biopsy samples for the rapid urease test and histological study, blood samples for serology, stool samples for HpSAT, and the 13C urea breath test. Criteria for infection was a positive result in at least two of the four diagnostic techniques, except in the case of HpSAT. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated., Results: Of the 32 patients, 23 (71.8%) were infected. The results of four HpSAT (12.5%) were negative and 28 were positive (87.5%). HpSAT showed high sensitivity (95.6%) but low specificity (33.3%). The PPV and NPV were 78.5% and 75% respectively. Of the 32 HpSAT, 25 (78.1) were performed in melenic stools: 22 were positive and 3 were negative. Seventy-five percent of negative HpSAT and 78.5% of positive HpSAT corresponded to melenic stools., Conclusions: HpSAT is a rapid, non-invasive technique that does not appear to be influenced by the presence of blood. Consequently, it can be applied in patients with upper gastrointestinal hemorrhage. The rapid urease test showed high sensitivity, specificity and PPV and should remain the first-line test in patients with upper gastrointestinal hemorrhage. HpSAT is appropriate as a second-line technique and is useful when the rapid urease test is negative and infection is strongly suspected, when no samples for the rapid urease test have been taken and when endoscopy cannot be performed. The result obtained in the present study should be confirmed in future studies with larger samples.
- Published
- 2001
43. [Evaluation of the efficacy of the endoscopic treatment in volvulus of the colon].
- Author
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López Peñas D, Naranjo Rodríguez A, Chicano Gallardo M, Rodríguez Gónzalez F, Hervás Molina A, Jiménez Sánchez JR, and Miño Fugarolas G
- Subjects
- Aged, Aged, 80 and over, Algorithms, Female, Follow-Up Studies, Humans, Male, Middle Aged, Retrospective Studies, Colonic Neoplasms therapy, Colonoscopy, Intestinal Obstruction therapy
- Abstract
Volvulus of the colon mainly affects the elderly and early surgery, with high morbidity and mortality, is often required. The efficacy of endoscopic devolvulization as an alternative is evaluated herein. From January 1993 to April 1999, 25 patients diagnosed with volvulus of the colon were retrospectively reviewed. Endoscopic devolvulization was not performed in one patient who showed signs of necrosis but was carried out in the remaining 24. The mean follow-up was 35.3 months. In all patients the procedure was initially effective. After the first attempt, 9 of the 24 patients (37%) relapsed, 4 out of 7 (57%) after a second attempt and 2 out of 2 (100%) after a third attempt. No morbidity or mortality was associated with the endoscopy. Six patients underwent surgery. Of these, none relapsed but two presented complications associated with the surgery. Mean hospital stay of the patients undergoing surgery was 30.8 days and that of those undergoing endoscopic devolvulization was 9.1 days. We conclude that endoscopic devolvulizatio is an effective therapeutic option when the mucosa is viable, with a high percentage of initial success, few complications inherent to the technique and with the possibility of carrying out a maximum of two attempts in cases of relapse. In the majority of patients, this technique is a valid alternative to urgent surgery, which has higher morbidity and mortality and longer mean hospital stay.
- Published
- 2000
44. [Resident physician training in the digestive system. The point of view of the residents].
- Author
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Rodríguez González FJ, Puente Gutiérrez J, Chicano Gallardo M, Monrobel Lancho A, López Peñas D, Bernal Blanco E, Naranjo Rodríguez A, and Miño Fugarolas G
- Subjects
- Adult, Data Collection, Employment, Endoscopy, Digestive System, Female, Gastroenterology instrumentation, Gastroenterology organization & administration, Humans, Male, Mentors, Personnel Staffing and Scheduling, Publishing statistics & numerical data, Spain, Specialization, Attitude of Health Personnel, Gastroenterology education, Internship and Residency standards
- Abstract
Aim: To evaluate various aspects of current training of Spanish residents in gastroenterology., Method: An anonymous postal questionnaire was sent to fourth-year resident physicians in Spanish hospitals with accredited gastroenterology residency programs., Results: Forty residents in the fourth year (53% offered positions), four from the second year and one from the first year (20 men, 25 women) answered the survey. Mean age was 29.7 years (26-42 years). Fifty-one percent of the departments did not have ultrasonography facilities apart from those in the radiology department. Endoscopic retrograde cholangiopancreatography (ERCP) was available in all the departments but in 55% of these, residents did not receive training in this technique. Forty-one percent of residents did not know the objectives of the various training periods. Eighty-four percent evaluated the pressure of clinical work as "intense" or "very intense" with 67% reporting that it disturbed their training "seriously" or "very seriously" and 71% that it disturbed their personal lives. Supervision in ultrasonography, endoscopy and clinical work were mainly evaluated as "good" or "very good". Supervision was rated lower in outpatient departments and while on duty. Forty-two percent of residents rated the supervision of the personal tutor as "average". Seventy-six percent were "fairly" or "very interested" in the introduction of "areas of specific training"., Conclusions: The quality of residents' training in general and of gastroenterology training in particular is high. There are, however, several aspects which could be improved.
- Published
- 2000
45. [The predictive factors of a good response to the transfusion of erythrocyte concentrates in patients with controlled digestive hemorrhage].
- Author
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González Galilea A, Monrobel Lancho A, Chicano Gallardo M, Puente Gutiérrez J, Gálvez Calderón C, and Miño Fugarolas G
- Subjects
- Adult, Aged, Aged, 80 and over, Chi-Square Distribution, Erythrocyte Indices, Female, Gastrointestinal Hemorrhage blood, Gastrointestinal Hemorrhage physiopathology, Hemodynamics, Humans, Logistic Models, Male, Middle Aged, Prognosis, Prospective Studies, Time Factors, Erythrocyte Transfusion statistics & numerical data, Gastrointestinal Hemorrhage therapy
- Abstract
Introduction: Not all patients respond the same to the transfusion of erythrocyte concentrates (EC) after achieving the control of gastrointestinal bleeding., Aim: The aim of the present study was to analyze the predictive factors of good response to EC transfusion in patients with controlled gastrointestinal hemorrhage and determine the stability of transfusion performance., Patients and Methods: A prospective study was carried out in 61 patients with controlled gastrointestinal bleeding. The epidemiologic data were compared and prior to transfusion different analytical and hemodynamic variables were compared basally. On completion of the transfusion analytical controls were performed at 4 and 24 hours. The response was considered as optimum when pretransfusional basal hemoglobin (Hb) increased at least 1 g and the hematocrit (HCT) rose 3 points for each EC administered., Results: The response to transfusion was optimum in 29 patients and bad in 32. The women responded significantly better than the men (p < 0.05), as did patients with lower weight (p < 0.05) and body surface (p < 0.05). The mean age of the responding patients was greater (p = 0.06) and the height, to the contrary, lower (p = 0.09). No significant differences were observed in the presence or not of associated disease, type of lesion causing the hemorrhage, or number of EC transfused. Likewise, no differences were found with regard to the pretransfusional values of TAM, TAS, FC, PVC, Hb, HCT, VCM, HCM, urea and creatinine. The only variables with independent predictive value of good response were female sex and low body surface. The difference between the Hb and HCT values at 4 and 24 h after transfusion did not achieve statistical significance., Conclusions: 1. The hemodynamic state and the degree of basal anemia do not condition response to EC transfusion in controlled gastrointestinal bleeding. 2. The response to the administration of EC is better in women and subjects of lower body surface. 3. Postransfusional analytical control at 4 hours allows early evaluation of the effects of the transfusion in patients at risk of recurrent hemorrhage.
- Published
- 1999
46. [Pulmonary mass which cavitated after bronchoscopy].
- Author
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Franco MA, Gallardo M, Conde A, Cruz JM, and Contreras M
- Subjects
- Aged, Animals, Diagnosis, Differential, Echinococcosis, Pulmonary diagnostic imaging, Echinococcosis, Pulmonary transmission, Environmental Exposure, Female, Humans, Lung Neoplasms diagnostic imaging, Sheep parasitology, Tomography, X-Ray Computed, Tuberculosis diagnostic imaging, Bronchoscopy, Echinococcosis, Pulmonary diagnosis
- Published
- 1998
47. [Tobacco dependence in primary care: the opinion of professionals in the Guadalajara Health Area].
- Author
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Alonso Gordo JM, Martínez Pérez JA, Arribas Aguirregaviria J, Sanchez-Seco Higueras P, Cuesta Gallardo M, and Provencio Hernando R
- Subjects
- Adult, Cross-Sectional Studies, Female, Health Knowledge, Attitudes, Practice, Health Personnel statistics & numerical data, Humans, Male, Prevalence, Smoking Cessation statistics & numerical data, Spain epidemiology, Surveys and Questionnaires, Tobacco Use Disorder epidemiology, Attitude of Health Personnel, Primary Health Care statistics & numerical data, Tobacco Use Disorder psychology
- Abstract
Objective: To find the views and approach of primary care professionals in this Health Area to questions referring to restrictions on tobacco consumption, possibilities of intervention and resources devoted to monitoring tobacco dependency., Design: A crossover study using an anonymous self-administered questionnaire with closed replies., Setting: Primary care professionals from the Guadalajara Health Area., Participants: Medical, nursing and other professional staff (361 people), with an 86.1% reply rate., Measurements and Main Results: 90.7% thought it was a good idea that tobacco consumption was legally regulated, although only 54.3% of non-smokers and 49.7% of doctors were in favour of extending the law. 37.5% of doctors and 19.5% of nurses (at the expense above all of non-smokers) were in favour of prioritizing care for non-smokers. Over 85% considered useful or very useful the introduction of methods to combat dependency in Health Centres and among health staff., Conclusions: There is a broad consensus on restricting tobacco consumption in determined places and applying methods in primary care to facilitate giving up tobacco. A critical attitude to the state on its tobacco policy was noted.
- Published
- 1997
48. [Influence of socioeconomic factors on the course and monitoring of pregnancy].
- Author
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Dueñas Herrero RM, Mitsuf Gallardo MJ, Martínez de la Iglesia J, Muñoz Alamo M, Fernández Fernández MJ, and Lora Cerezo N
- Subjects
- Adolescent, Adult, Female, Humans, Retrospective Studies, Rural Population, Socioeconomic Factors, Urban Population, Pregnancy, Prenatal Care statistics & numerical data
- Abstract
Objective: To analyse variations in monitoring the pregnancy programme (PP) and in the programme's development in three population groups distinguished by their socio-demographic characteristics., Design: An observational, descriptive and retrospective study., Setting: "Occidente" Health District, Córdoba., Participants: Women who finalised their pregnancy in 1994 or 1995 (n = 415) and who lived in three zones distinguished geographically and socially: an Urban Area (UA), with an average population socially and economically and urban environment; a Marginal Area (MA) with a low social and economic level, high rates of unemployment and drug addiction, and a mixed population (gypsy and latin); and a Rural Area (RA), which had a rural productive way of life., Measurements: The area of residence was related to the socio-demographic variables, history, drug consumption, PP monitoring and identified pathology., Results: PP coverage reached 73.8% (CI 69.2-77.8), Pregnant women living in the MA were younger (p < 0.001), and included more adolescents (p < 0.001) and more single women (p < 0.001)., Conclusions: Poorer monitoring and adherence to the PP by the MA population could be confirmed.
- Published
- 1997
49. [Pericardial tamponade as initial manifestation of pulmonary tuberculosis].
- Author
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Gallardo M, Romero PJ, and Sánchez-Palencia A
- Subjects
- Humans, Male, Middle Aged, Pericardium, Cardiac Tamponade microbiology, Tuberculosis, Pulmonary complications
- Published
- 1994
50. [Liver and kidney disorders in icterohemorrhagic leptospirosis. Apropos of 6 cases].
- Author
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Ortega Suárez R, Baños Gallardo M, Alonso Alvarez M, Marín Iranzo R, Alvarez Grande J, Faedo Presa I, Rodrigo Sáez L, Prendes Peláez P, Alvarez Fernández M, and Fuentes Martín E
- Subjects
- Adult, Aged, Disease Outbreaks, Humans, Kidney pathology, Liver pathology, Male, Middle Aged, Nephritis, Interstitial etiology, Spain, Weil Disease epidemiology, Acute Kidney Injury etiology, Liver Diseases etiology, Weil Disease complications
- Published
- 1981
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