Ana Cristina Gales, Mara Cristina Scheffer, José Rodrigues do Carmo Filho, Libera Maria Dalla-Costa, Afonso Luis Barth, Univ Fed Parana, Universidade Federal de Santa Catarina (UFSC), Universidade Federal de São Paulo (UNIFESP), Hosp Clin Porto Alegre, Univ Catolica Goias, and Fac Pequeno Principe
This study evaluated the clonal spread of carbapenem-resistant P. aeruginosa producing SPM-1 type metallo-beta-lactamase (MBL), at the university hospital of Florianopolis, Santa Catarina, Brazil, compared to an epidemic clone previously reported, as well as strains collected in other three Brazilian states. Among the isolates, 17 (62%) were clonal and highly related to strains from other regions of Brazil. Six clonal strains harbored the bla(SPM-1) gene. the finding of a unique SPM-1 producer clone suggests that its dissemination has contributed to the high resistance to carbapenems in Brazilian hospitals. Univ Fed Parana, Hosp Clin, Serv Anal Clin, BR-80060000 Curitiba, Parana, Brazil Univ Fed Santa Catarina, Univ Hosp, Serv Patol Clin, BR-88040900 Florianopolis, SC, Brazil Universidade Federal de São Paulo, Dept Doencas Infecciosas, São Paulo, Brazil Hosp Clin Porto Alegre, Serv Patol Clin, Porto Alegre, RS, Brazil Univ Catolica Goias, Dept Enfermagem, Goiania, Go, Brazil Univ Catolica Goias, Dept Med, Goiania, Go, Brazil Fac Pequeno Principe, Inst Pesquisa Pele Pequeno Principe, Curitiba, Parana, Brazil Universidade Federal de São Paulo, Dept Doencas Infecciosas, São Paulo, Brazil Web of Science