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Your search keyword '"Zdunczyk, A."' showing total 43 results
Start Over Author "Zdunczyk, A." Publisher elsevier bv
43 results on '"Zdunczyk, A."'

16. FV 9. How Degenerative Cervical Myelopathy Affects the Functional Imaging Correlates of the Somatosensory Cortex

Author

Roland Goldbrunner, A. Zdunczyk, Thorsten Lichtenstein, C. Nettekoven, L. Hams, C. Weiß Lucas, and Peter Vajkoczy

Subjects
Functional imaging, Pathology, medicine.medical_specialty, Myelopathy, Neurology, business.industry, Physiology (medical), Medicine, Neurology (clinical), Somatosensory system, business, medicine.disease, Sensory Systems
Published
2021
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18. Language mapping in healthy volunteers and brain tumor patients with a novel navigated TMS system: Evidence of tumor-induced plasticity

Author

Dietmar Frey, Valerie Strack, Pantelis Lioumis, Thomas Picht, Birat Niraula, Judith Rösler, Petri Ilmari Savolainen, Anna Zdunczyk, Peter Vajkoczy, Jyrki P. Mäkelä, and Sarah Schilt

Subjects
Adult, Male, medicine.medical_specialty, medicine.medical_treatment, Brain tumor, Stimulation, Audiology, Language mapping, 050105 experimental psychology, Lateralization of brain function, 03 medical and health sciences, Epilepsy, 0302 clinical medicine, Physiology (medical), Cortex (anatomy), medicine, Humans, 0501 psychology and cognitive sciences, Aged, Language, Brain Mapping, Language Tests, Neuronal Plasticity, Psycholinguistics, medicine.diagnostic_test, Brain Neoplasms, 05 social sciences, Brain, Middle Aged, medicine.disease, Magnetic Resonance Imaging, Transcranial Magnetic Stimulation, Healthy Volunteers, Sensory Systems, Semantics, Transcranial magnetic stimulation, medicine.anatomical_structure, Neurology, Positron emission tomography, Preoperative Period, Female, Neurology (clinical), Psychology, Neuroscience, Craniotomy, 030217 neurology & neurosurgery
Abstract

Objective This article explores the feasibility of a novel repetitive navigated transcranial magnetic stimulation (rnTMS) system and compares language mapping results obtained by rnTMS in healthy volunteers and brain tumor patients. Methods Fifteen right-handed healthy volunteers and 50 right-handed consecutive patients with left-sided gliomas were examined with a picture-naming task combined with time-locked rnTMS (5–10 Hz and 80–120% resting motor threshold) applied over both hemispheres. Induced errors were classified into four psycholinguistic types and assigned to their respective cortical areas according to the coil position during stimulation. Results In healthy volunteers, language disturbances were almost exclusively induced in the left hemisphere. In patients errors were more frequent and induced at a comparative rate over both hemispheres. Predominantly dysarthric errors were induced in volunteers, whereas semantic errors were most frequent in the patient group. Conclusion The right hemisphere’s increased sensitivity to rnTMS suggests reorganization in language representation in brain tumor patients. Significance rnTMS is a novel technology for exploring cortical language representation. This study proves the feasibility and safety of rnTMS in patients with brain tumor.

Published
2014
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23. P 93 TMS recruitment curve and cortical silent period analysis: a sensitive tool to detect imminent motor deficits in brain tumor patients

Author

Ina Bährend, Anna Zdunczyk, Heike Schneider, Thomas Picht, Vera Schwarzer, Ulrike Grittner, R. Tizian, and Peter Vajkoczy

Subjects
Motor disorder, medicine.medical_specialty, medicine.medical_treatment, Brain tumor, Neurophysiology, medicine.disease, Sensory Systems, Surgery, Transcranial magnetic stimulation, Correlation, Neurology, Physiology (medical), Internal medicine, medicine, Cardiology, Silent period, Neurology (clinical), Primary motor cortex, medicine.symptom, Psychology, Muscle contraction
Abstract

Background One of the challenges in surgery of tumors in motor eloquent areas is the individual risk assessment for postoperative motor disorder. Previously, we developed a predictive model that allows for objective evaluation of this risk prior to surgery based on topographical and neurophysiologial data derived from investigation with nTMS (navigated Transcranial Magnetic Stimulation). The input variables of the model are: (1) presence of infiltration of the primary motor cortex by the tumor, (2) the minimal distance of the tumor to the corticalspinal tract and (3) the ratio of the bihemispheric resting motor threshold (RMT). The aim of this study is the improvement of the prognostic power of the aforementioned model by including additional neurophysiological parameters: Recruitment Curve (RC) and Cortical Silent Period (CSP). Methods nTMS was used to map the cortical motor representation area of the FDI muscle in 149 patients with malignant gliomas in presumed motor eloquent areas prior to surgery. In addition to RMT determination, the RC was measured by applying 70 stimuli of randomized intensity between 80% and 150% of the RMT over the FDI hot spot. CSP was determined by applying 10 stimuli of 130% RMT intensity during tonic muscle contraction and measuring the duration of the plateau phase from EMG recording. Each metric was measured bihemispherically. Finally, the ratio between left and right hemisphere is calculated. For definition of a physiologic range, a control group of 17 healthy volunteers was investigated with the same protocol. In order to quantify the motor function we evaluated the muscle strength according to the British Medical Research Council Scale preoperatively and postoperatively after seven days and three months. Results In respect to the postoperative motor outcome after seven days, the RMT Ratio’s predictive value was confirmed (p = 0,036). Yet, in respect to the postoperative motor outcome after three months no significant correlation could be found (p = 0,16). For the CSP Ratio no correlation to the postoperative motor status was observed. A tendency to an increased presurgical cortical GABAergic inhibition in patients with new postoperative deficits was recognizable, but is was significant for neither the seventh postoperative day (p = 0,19) nor after three months (p = 0,75). For the presurgical RC Ratio on the other hand, a significant correlation to the preoperative motor status (p = 0,029) as well as for postoperative deterioration of motor function after three months in patients with cortico-subcortical tumors was found (p = 0,004). Conclusions Addition of the RC Ratio significantly improved the value of the nTMS based predictive model, since the RC Ratio allows for prediction of new motor deficits 3 month after surgery. Addition of the CSP Ratio on the other hand did not, based on the current analysis, add predictive power to the model. The predictive power of the previously established correlation between presurgical RMT Ratio and motor status on day 7 was improved based on the larger study sample. The current results demonstrate that the RC Ratio and the RMT Ratio are sensitive markers to predict the motor outcome 7 days and 3 month after surgery of brain tumors in presumed motor eloquent location and can therefore supply valuable information during preoperative risk-benefit-balancing.

Published
2017
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36. Biological response of rat fed diets with high tuber content of conventionally bred and transgenic potato resistant to necrotic strain of potato virus (PVYN). Part II. Caecal metabolism, serum enzymes and indices of non-specific defence of rats

Author

Zdunczyk, Z., primary, Juskiewicz, J., additional, Fornal, J., additional, Mazur-Gonkowska, B., additional, Koncicki, A., additional, Flis, B., additional, Zimnoch-Guzowska, E., additional, and Zagorski-Ostoja, W., additional

Published
2005
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43. Improving the quality of sous-vide beef from Holstein-Friesian bulls by different marinades

Author

Weronika Zduńczyk, Massimiliano Petracci, Katarzyna Tkacz, Monika Modzelewska-Kapituła, Tkacz K., Modzelewska-Kapitula M., Petracci M., and Zdunczyk W.

Subjects
Male, Taste, Sous vide, Color, Hamstring Muscles, Biology, Sensory quality, Pepper, medicine, Animals, Humans, Cooking, Texture, Food science, Beef quality, Marinating, fungi, food and beverages, Tenderness, Red Meat, Sous-vide, Cattle, Female, medicine.symptom, Shear Strength, Food Science
Abstract

The aim of the study was to determine effects of four commercial marinades on the colour, tenderness, cooking loss and sensory characteristics of semimembranosus beef muscles before and after sous-vide (SV) treatment. Muscles (n = 24) were marinated using Odessa (O; red pepper, garlic, onion), Mexico (M; red pepper, tomato), Old Polish (OP; pepper, garlic), and Bordeaux (B; pepper, red pepper, garlic) marinades for 24 h at 4 °C. Marinades uptake ranged from 3.3% (M) to 4.4% (B). Marinating and SV significantly affected all colour parameters. In SV beef, the highest values of L* were noted in OP and O samples, whereas the highest a* and b* values in M samples. Overall, marinating reduced (P < 0.05) cooking loss (34.6%) and shear force (19.5%). The use of marinating prior to SV treatment beneficially affected taste, tenderness and juiciness of beef. OP marinade allowed to obtain beef steaks with the best sensory quality and the lowest shear force.

Published
2021
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