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Start Over Author "Yong-Rong Yang" Publisher elsevier bv
2 results on '"Yong-Rong Yang"'

1. Fe powder catalyzed highly efficient synthesis of alkenyl halides via direct coupling of alcohols and alkynes with aqueous HX as exogenous halide sources

Author

Jian-Xin Ji, Feng-Tian Du, Qiang Zhang, and Yong-Rong Yang

Subjects
Metal contamination, Aqueous solution, Chemistry, Organic Chemistry, Drug Discovery, High loading, Halide, Direct coupling, Biochemistry, Combinatorial chemistry, Catalytic method, Catalysis
Abstract

A simple and efficient catalytic method for the synthesis of alkenyl halides via direct coupling of alcohols and alkynes using aqueous HX (X=Cl, Br) as halide sources has been developed under mild conditions in the presence of Fe powder (1 mol %). In comparison with the high loading of FeX3 in previously reported protocols, the present approach provides a remarkable attractive methodology to a diverse range of alkenyl halides due to the advantages of simple operation and low-level metal contamination.

Published
2015
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