Search

Your search keyword '"Xu, Yinfeng"' showing total 82 results
Start Over Author "Xu, Yinfeng" Publisher elsevier bv
82 results on '"Xu, Yinfeng"'

10. A novel human anti-TIGIT monoclonal antibody with excellent function in eliciting NK cell-mediated antitumor immunity

Author

Han, Dong, primary, Xu, Yinfeng, additional, Zhao, Xinping, additional, Mao, Yunyun, additional, Kang, Qinglin, additional, Wen, Weihong, additional, Yu, Xiaoyan, additional, Xu, Lei, additional, Liu, Fujia, additional, Zhang, Mengyao, additional, Cui, Jiazhen, additional, Wang, Zhang, additional, Yang, Zhixin, additional, Du, Peng, additional, and Qin, Weijun, additional

Published
2021
Full Text
View/download PDF

25. Coexpression of the mutated BRCA1 mRNA and p53 mRNA and its association in Chinese prostate cancer

Author

Hai-Fei Fang, Yi-Lin Ding, Zui-Su Yang, Xu Yinfeng, Hong-Ping Zhao, and Guo-Fang Ding

Subjects
Male, PCA3, China, Tumor suppressor gene, Angiogenesis, Urology, Biology, Metastasis, Prostate cancer, Asian People, medicine, Humans, RNA, Messenger, Survival rate, In Situ Hybridization, Aged, Neoplasm Staging, Aged, 80 and over, Regulation of gene expression, BRCA1 Protein, Prostatic Neoplasms, Cancer, Middle Aged, Prognosis, medicine.disease, Survival Analysis, Gene Expression Regulation, Neoplastic, Oncology, Mutation, Cancer research, Tumor Suppressor Protein p53
Abstract

The mutations of BRCA1 and p53 genes have been simultaneously characterized in many tumors. However, their coexpression and associations have not been investigated quantitatively in prostate cancer. In the present study, the expressions of the mutated BRCA1 mRNA and p53 mRNA were examined in 48 Chinese prostate cancer cases and 10 corresponding adjacent benign tissues with in situ hybridization. The 5-year survival rates of the corresponding patients after operation were investigated. The results showed that the positive expressions of the mutated BCRA1 mRNA and p53 mRNA are involved in prostate cancer (P < 0.05). Moreover, there is a closed negative association between the expressions of the mutated BRCA1 gene and p53 gene in the mRNA level with the progression, angiogenesis, metastasis, and survival rate of prostate cancer. Their coexpression and negative association suggest that the two altered tumor suppressor genes might interact functionally in prostate cancer to provide a potential signal determining a prognosis of the tumor metastasis and survival rate. Further work will be done to elucidate the interaction mechanisms in prostate cancer.

Published
2011

26. Optimal algorithms for the online time series search problem

Author

Xu, Yinfeng, Zhang, Wenming, and Zheng, Feifeng

Subjects
General Computer Science, Profit function, Online algorithm, Time series search, Computer Science(all), Competitive ratio, Theoretical Computer Science
Abstract

In the problem of online time series search introduced by El-Yaniv et al. (2001) [1], a player observes prices one by one over time and shall select exactly one of the prices on its arrival without the knowledge of future prices, aiming to maximize the selected price. In this paper, we extend the problem by introducing profit function. Considering two cases where the search duration is either known or unknown beforehand, we propose two optimal deterministic algorithms respectively. The models and results in this paper generalize those of El-Yaniv et al. (2001) [1].

Published
2011

27. Online Risk-Reward Model for Time-Cost Tradeoff in Project Management

Author

Guan-qun Ni, Xiao-wen Xu, and Xu Yinfeng

Subjects
Operations research, Competitive analysis, Work (electrical), business.industry, Economics, Operations management, Competitor analysis, Project management, Online algorithm, business, Critical path method, Time cost, Project manager
Abstract

Taking into account the uncertain delay of work on the critical path, the online strategy and competitive analysis are introduced into time-cost optimizing in project management. The competitive ratio of the strategy is given, and the prerushing strategy is proved to be the best determinate one. The relationship between the general strategy and the optimal offline strategy is analyzed, and three properties are discovered. On this basis, this article designs the risk-tolerance strategy and proves its competitive ratio to help the project manager in choosing the optimal strategy according to his own risk tolerance and forecast.

Published
2009

Catalog

Books, media, physical & digital resources
See catalog results