1. Sperm motility analysis system implemented on a hybrid architecture to produce an intelligent analyzer
- Author
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Vedat Tavsanoglu, Osman Levent Şavkay, Mustak E. Yalcin, Işık Üniversitesi, Mühendislik Fakültesi, Elektrik-Elektronik Mühendisliği Bölümü, Işık University, Faculty of Engineering, Department of Electrical-Electronics Engineering, and Tavşanoğlu, Ahmet Vedat
- Subjects
0301 basic medicine ,Object determination ,Health Informatics ,Semen analysis ,lcsh:Computer applications to medicine. Medical informatics ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Semen sample ,Sperm analysis ,FPGA ,Real-time operating system ,Sperm motility ,Medical education ,medicine.diagnostic_test ,Tracking ,Motility ,Spermatozoa ,Treatment center ,030104 developmental biology ,030220 oncology & carcinogenesis ,lcsh:R858-859.7 ,Semen samples ,Psychology - Abstract
Much research and analysis in biomedicine involve image and video inspection using microscopes. Presently, scientists are dissatisfied with manual observations and assessments, when objective and enhanced data can be obtained by applying new technologies (such as image and video inspection) to biomedical fields, such as sperm analysis. Computer Assisted Sperm Analysis (CASA) systems, developed in the late 1980s, constitute third-generation methods of sperm analysis. This study aimed to develop a standalone medical image and video analysis system that is reconfigurable, flexible, reliable, deterministic, and robust. It proposed a new sperm motility analysis system running on a dual core Central Processing Unit (CPU) + field programmable gate arrays (FPGA) platform, under a real-time operating system (RTOS), which is a step ahead of the third-generation CASA systems. The system hardware and related sperm detection and tracking algorithms were the novelty of this work. The image processing functions mainly run on FPGA, image acquisition, and calculations run on CPU, parallel with FPGA. The result is a much faster, reliable, reconfigurable, and compact intelligent analyzer system. Our prototype system was applied to sperm motility analysis; however, other image processing systems can be applied to this architecture. Additionally, the proposed tracking method for sperm track determination is simple, effective, and does not exert a load on the system. We are thankful to Prof. Dr. Erol Tavmergen, Ege University Family Planning, Infertility Research and Treatment Center, and the laboratory people at the center for their support, help and for providing human semen samples and comments on motility analysis. We also thank Geli?im T?p (Medical) Laboratory for showing and introducing us to their CASA system, for taking semen sample videos and providing comments on sperm analysis. We are thankful to Assist. Prof. Dr. Kamber Demir, Dr. Ramazan Ar?c?, Dr. Ahmet Eser from ?stanbul University ? Cerrahpa?a Faculty of Veterinary Medicine, Department of Reproduction and Artificial Insemination, for opening the laboratories, their comments and their help in conducting the tests and providing the samples. Publisher's Version
- Published
- 2020