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3. The Silicon Vertex Detector of the Belle II experiment

Author

Wang, Z., primary, Adamczyk, K., additional, Aggarwal, L., additional, Aihara, H., additional, Aziz, T., additional, Bacher, S., additional, Bahinipati, S., additional, Batignani, G., additional, Baudot, J., additional, Behera, P.K., additional, Bettarini, S., additional, Bilka, T., additional, Bozek, A., additional, Buchsteiner, F., additional, Casarosa, G., additional, Corona, L., additional, Das, S.B., additional, Dujany, G., additional, Finck, C., additional, Forti, F., additional, Friedl, M., additional, Gabrielli, A., additional, Gobbo, B., additional, Halder, S., additional, Hara, K., additional, Hazra, S., additional, Higuchi, T., additional, Irmler, C., additional, Ishikawa, A., additional, Jin, Y., additional, Kaleta, M., additional, Kaliyar, A.B., additional, Kandra, J., additional, Kang, K.H., additional, Kodyš, P., additional, Kohriki, T., additional, Kumar, R., additional, Lalwani, K., additional, Lautenbach, K., additional, Leboucher, R., additional, Lee, S.C., additional, Libby, J., additional, Martel, L., additional, Massaccesi, L., additional, Mohanty, G.B., additional, Mondal, S., additional, Nakamura, K.R., additional, Natkaniec, Z., additional, Onuki, Y., additional, Otani, F., additional, Paladino, A., additional, Paoloni, E., additional, Park, H., additional, Polat, L., additional, Rao, K.K., additional, Ripp-Baudot, I., additional, Rizzo, G., additional, Sato, Y., additional, Schwanda, C., additional, Serrano, J., additional, Shimasaki, T., additional, Suzuki, J., additional, Tanaka, S., additional, Tanigawa, H., additional, Tenchini, F., additional, Thalmeier, R., additional, Tiwary, R., additional, Tsuboyama, T., additional, Uematsu, Y., additional, Vitale, L., additional, Webb, J., additional, Werbycka, O., additional, Wiechczynski, J., additional, Yin, H., additional, and Zani, L., additional

Published
2024
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4. Recent advances in artificial intelligence for cardiac CT: Enhancing diagnosis and prognosis prediction

Author

Tatsugami, Fuminari, primary, Nakaura, Takeshi, additional, Yanagawa, Masahiro, additional, Fujita, Shohei, additional, Kamagata, Koji, additional, Ito, Rintaro, additional, Kawamura, Mariko, additional, Fushimi, Yasutaka, additional, Ueda, Daiju, additional, Matsui, Yusuke, additional, Yamada, Akira, additional, Fujima, Noriyuki, additional, Fujioka, Tomoyuki, additional, Nozaki, Taiki, additional, Tsuboyama, Takahiro, additional, Hirata, Kenji, additional, and Naganawa, Shinji, additional

Published
2023
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5. Phase III trial of short-course radiotherapy followed by CAPOXIRI versus CAPOX in locally advanced rectal cancer: the ENSEMBLE trial

Author

Watanabe, J., primary, Kagawa, Y., additional, Chida, K., additional, Ando, K., additional, Kotani, D., additional, Oba, K., additional, Bando, H., additional, Hojo, H., additional, Shimamoto, S., additional, Sakashita, S., additional, Kuwata, T., additional, Tsuboyama, T., additional, Hosomi, N., additional, Uemura, M., additional, Uehara, K., additional, Ito, M., additional, Oki, E., additional, Takemasa, I., additional, Misugi, E., additional, Sledge, G., additional, Sumani, K., additional, Imoto, S., additional, Kato, T., additional, and Yoshino, T., additional

Published
2023
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6. The silicon vertex detector of the Belle II experiment

Author

Irmler, C., primary, Adamczyk, K., additional, Aggarwal, L., additional, Aihara, H., additional, Aziz, T., additional, Bacher, S., additional, Bahinipati, S., additional, Batignani, G., additional, Baudot, J., additional, Behera, P.K., additional, Bettarini, S., additional, Bilka, T., additional, Bozek, A., additional, Buchsteiner, F., additional, Casarosa, G., additional, Corona, L., additional, Czank, T., additional, Das, S.B., additional, Dujany, G., additional, Finck, C., additional, Forti, F., additional, Friedl, M., additional, Gabrielli, A., additional, Ganiev, E., additional, Gobbo, B., additional, Halder, S., additional, Hara, K., additional, Hazra, S., additional, Higuchi, T., additional, Ishikawa, A., additional, Jeon, H.B., additional, Jin, Y., additional, Kaleta, M., additional, Kaliyar, A.B., additional, Kandra, J., additional, Kang, K.H., additional, Kapusta, P., additional, Kodyš, P., additional, Kohriki, T., additional, Kumar, M., additional, Kumar, R., additional, La Licata, C., additional, Lalwani, K., additional, Lautenbach, K., additional, Leboucher, R., additional, Lee, S.C., additional, Libby, J., additional, Martel, L., additional, Massaccesi, L., additional, Mohanty, G.B., additional, Nakamura, K.R., additional, Natkaniec, Z., additional, Onuki, Y., additional, Ostrowicz, W., additional, Otani, F., additional, Paladino, A., additional, Paoloni, E., additional, Park, H., additional, Polat, L., additional, Rao, K.K., additional, Ripp-Baudot, I., additional, Rizzo, G., additional, Sato, Y., additional, Schwanda, C., additional, Serrano, J., additional, Shimasaki, T., additional, Suzuki, J., additional, Tanaka, S., additional, Tanigawa, H., additional, Tenchini, F., additional, Thalmeier, R., additional, Tiwary, R., additional, Tsuboyama, T., additional, Uematsu, Y., additional, Vitale, L., additional, Wan, K., additional, Wang, Z., additional, Webb, J., additional, Werbycka, O., additional, Wiechczynski, J., additional, Yin, H., additional, and Zani, L., additional

Published
2023
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7. Pancreatic fibrosis by extracellular volume fraction using Contrast-enhanced computed tomography and relationship with pancreatic cancer

Author

Fukui, Hideyuki, primary, Onishi, Hiromitsu, additional, Nakamoto, Atsushi, additional, Tsuboyama, Takahiro, additional, Ota, Takashi, additional, Yano, Keigo, additional, Enchi, Yukihiro, additional, Yamada, Daisaku, additional, Takeda, Yu, additional, Kobayashi, Shogo, additional, Fukuda, Yasunari, additional, Eguchi, Hidetoshi, additional, Matsui, Takahiro, additional, Tatsumi, Mitsuaki, additional, and Tomiyama, Noriyuki, additional

Published
2022
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8. Measurements of beam backgrounds in SuperKEKB Phase 2

Author

Liptak, Z., primary, Paladino, A., additional, Santelj, L., additional, Schueler, J., additional, Stefkova, S., additional, Tanigawa, H., additional, Tsuzuki, N., additional, Aloisio, A., additional, Ahlburg, P., additional, Bambade, P., additional, Bassi, G., additional, Barrett, M., additional, Baudot, J., additional, Browder, T.E., additional, Casarosa, G., additional, Cautero, G., additional, Cinabro, D., additional, Claus, G., additional, Cuesta, D., additional, Di Capua, F., additional, Di Carlo, S., additional, Flanagan, J., additional, Frey, A., additional, Fulsom, B.G., additional, Funakoshi, Y., additional, Gabriel, M., additional, Giordano, R., additional, Giuressi, D., additional, Goffe, M., additional, Hara, K., additional, Hartbrich, O., additional, Hedges, M.T., additional, Heuchel, D., additional, Iida, N., additional, Ishibashi, T., additional, Jaaskelainen, K., additional, Jehanno, D., additional, de Jong, S., additional, Kraetzschmar, T., additional, La Licata, C., additional, Lanceri, L., additional, Leitl, P., additional, Lewis, P.M., additional, Marinas, C., additional, Miller, C., additional, Moser, H., additional, Nakamura, K.R., additional, Nakayama, H., additional, Niebuhr, C., additional, Onuki, Y., additional, Pang, C., additional, Paschen, B., additional, Ripp-Baudot, I., additional, Rizzo, G., additional, Roney, J.M., additional, Schreeck, H., additional, Schwenker, B., additional, Simon, F., additional, Specht, M., additional, Spruck, B., additional, Soloviev, Y., additional, Szelezniak, M., additional, Tanaka, S., additional, Terui, S., additional, Tortone, G., additional, Tsuboyama, T., additional, Uematsu, Y., additional, Vahsen, S.E., additional, Vitale, L., additional, and Windel, H., additional

Published
2022
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11. The Silicon Vertex Detector of the Belle II experiment

Author

Zani, L., primary, Adamczyk, K., additional, Aggarwal, L., additional, Aihara, H., additional, Aziz, T., additional, Bacher, S., additional, Bahinipati, S., additional, Batignani, G., additional, Baudot, J., additional, Behera, P.K., additional, Bettarini, S., additional, Bilka, T., additional, Bozek, A., additional, Buchsteiner, F., additional, Casarosa, G., additional, Corona, L., additional, Czank, T., additional, Das, S.B., additional, Dujany, G., additional, Finck, C., additional, Forti, F., additional, Friedl, M., additional, Gabrielli, A., additional, Ganiev, E., additional, Gobbo, B., additional, Halder, S., additional, Hara, K., additional, Hazra, S., additional, Higuchi, T., additional, Irmler, C., additional, Ishikawa, A., additional, Jeon, H.B., additional, Jin, Y., additional, Kaleta, M., additional, Kaliyar, A.B., additional, Kandra, J., additional, Kang, K.H., additional, Kapusta, P., additional, Kodyš, P., additional, Kohriki, T., additional, Kumar, M., additional, Kumar, R., additional, La Licata, C., additional, Lalwani, K., additional, Leboucher, R., additional, Lee, S.C., additional, Libby, J., additional, Martel, L., additional, Massaccesi, L., additional, Mayekar, S.N., additional, Mohanty, G.B., additional, Morii, T., additional, Nakamura, K.R., additional, Natkaniec, Z., additional, Onuki, Y., additional, Ostrowicz, W., additional, Paladino, A., additional, Paoloni, E., additional, Park, H., additional, Polat, L., additional, Rao, K.K., additional, Ripp-Baudot, I., additional, Rizzo, G., additional, Sahoo, D., additional, Schwanda, C., additional, Serrano, J., additional, Suzuki, J., additional, Tanaka, S., additional, Tanigawa, H., additional, Thalmeier, R., additional, Tiwary, R., additional, Tsuboyama, T., additional, Uematsu, Y., additional, Vitale, L., additional, Wan, K., additional, Wang, Z., additional, Webb, J., additional, Werbycka, O., additional, Wiechczynski, J., additional, and Yin, H., additional

Published
2022
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12. The Belle II vertex detector integration

Author

H. Windel, V. Babu, S. Skambraks, P. Mammini, Ti. Baroncelli, M. Kaleta, C. Koffmane, M. Hensel, G. Batignani, J. Stypula, Prafulla Kumar Behera, V. Chekelian, C. La Licata, C. Wessel, H. Aihara, D. Münchow, F. Müller, M. Heck, J. Sanchez, F. Abudinen, AL Virto, F. Mueller, Oscar Alonso, R. Thalmeier, D. Klose, I. J. Watson, Soumen Paul, U. Packheiser, M. Ceccanti, N. Sato, Dipak Kumar Sahoo, D. Moya, B. Scavino, M. Fras, K. K. Rao, Takeo Higuchi, R. Richter, M. Albalawi, K. Nakamura, T. Kohriki, L. Zani, S. N. Mayekar, Svd Collaborations, Jakub Kandra, K. Prasanth, L. Macharski, S. Bacher, T. Morii, S. Bettarini, Jelena Ninkovic, Michael Ritzert, L. Bosisio, Jochen Dingfelder, Florian Schopper, Markus Friedl, D. Esperante, Ladislav Andricek, C. Kiesling, M. Boronat, H. Park, A. Bozek, Satoshi Tanaka, Tariq Aziz, Concettina Sfienti, C. W. Joo, R. Ayad, Seema Bahinipati, F. Lütticke, M. De Nuccio, U. Gebauer, Benjamin Schwenker, Zhiyong Liu, Steven Williams, Z. Natkaniec, Norbert Wermes, Carlos Marinas, B. Bhuyan, C. Schwanda, Shih-Chang Lee, T. Kuhr, G. Rizzo, W. Ostrowicz, S. Krivokuca, Frank Simon, B. Paschen, Maiko Takahashi, S. Vogt, H. G. Moser, R. Stever, Angel Dieguez, L. Gioi, F. Buchsteiner, Gerhard Schaller, H. Tanigawa, M. Gabriel, M. Hoek, A. Paladino, Rakesh Kumar, Gerhard Liemann, D. Getzkow, Peter Kvasnicka, B. Spruck, J.A.M. Grimaldo, Y. Onuki, K. H. Kang, T. Lueck, F. Poblotzki, S. Mccarney, P. K. Resmi, S. Schultschik, B. Gobbo, K. Lalwani, S. Rummel, D. Kittlinger, Ivan Peric, K. Gadow, Allen Caldwell, Martin Ritter, Dmytro Levit, Gagan Bihari Mohanty, To. Baroncelli, Keigo Hara, E. L. Barberio, F. Forti, L. Germic, U. Leis, A. Profeti, Tomasz Hemperek, S. Koike, B. Kisielewski, Marcel Vos, Peter Kodys, A. Bauer, P. Leitl, K. Ackermann, Ilya Komarov, Giulia Casarosa, H. Yin, Y. Soloviev, Jae-Young Lee, J. Fuster, Thomas Gessler, H. Schreeck, Phillip Urquijo, A. Martini, E. Paoloni, Carlos Lacasta, D. Červenkov, U. Stolzenberg, Pxd Belle Ii Depfet, L. Lanceri, I. Konorov, N. Dash, T. Czank, R. Blanco, G. N. Taylor, P. Wieduwilt, J. Suzuki, I. Rashevskaya, Hans Krüger, A. K. Basith, M. Rozanska, C. H. Wang, P. Kapusta, J. S. Lange, A. Rabusov, H. B. Jeon, Ivan Vila, A. Ishikawa, M. Schnecke, Filippo Bosi, T. Bilka, M. Watanabe, H. Ye, G. Caria, P. Gomis, E. Tafelmayer, M. Kumar, A. Frey, Jun Sasaki, J. Libby, K. Lautenbach, B. Deschamps, R. Sedlmeyer, Shoichi Watanuki, V. Bertacchi, Z. Doležal, S. Reiter, N. Kambara, Christian Irmler, C. Camien, T. Tsuboyama, J. Wiechczynski, Peter Fischer, W. Kun, P. Ahlburg, Wolfgang Kuhn, John Webb, L. Vitale, J. Zhao, Y. Bai, C. Niebuhr, European Commission, Ministerio de Economía y Competitividad (España), Ministry of Education, Culture, Sports, Science and Technology (Japan), Japan Society for the Promotion of Science, WPI Immunology Frontier Research Center (Japan), Federal Ministry of Science, Research and Economy (Austria), Australian Research Council, Ministry of Education, Youth and Sports (Czech Republic), Government of Czech Republic, Department of Science and Technology (India), Department of Atomic Energy (India), National Research Foundation of Korea, Ministry of Science and Higher Education (Poland), Federal Ministry of Science, Research and Economy (Germany), Kodyš, P., Abudinen, F., Ackermann, K., Ahlburg, P., Aihara, H., Albalawi, M., Alonso, O., Andricek, L., Ayad, R., Aziz, T., Babu, V., Bacher, S., Bahinipati, S., Bai, Y., Barberio, E., Baroncelli, Ti., Baroncelli, To., Basith, A. K., Batignani, G., Bauer, A., Behera, P. K., Bertacchi, V., Bettarini, S., Bhuyan, B., Bilka, T., Blanco, R., Bosi, F., Boronat, M., Bosisio, L., Bozek, A., Buchsteiner, F., Camien, C., Caldwell, A., Caria, G., Casarosa, G., Ceccanti, M., Červenkov, D., Chekelian, V., Czank, T., Dash, N., De Nuccio, M., Deschamps, B., Dieguez, A., Dingfelder, J., Doležal, Z., Esperante, D., Fischer, P., Forti, F., Fras, M., Frey, A., Friedl, M., Fuster, J., Gabriel, M., Gadow, K., Gebauer, U., Germic, L., Gessler, T., Getzkow, D., Gioi, L., Gobbo, B., Gomis, P., Grimaldo, J. A. M., Hara, K., Heck, M., Hemperek, T., Hensel, M., Higuchi, T., Hoek, M., Irmler, C., Ishikawa, A., Jeon, H. B., Joo, C., Kaleta, M., Kandra, J., Kambara, N., Kang, K. H., Kapusta, P., Kiesling, C., Kisielewski, B., Kittlinger, D., Klose, D., Koffmane, C., Kohriki, T., Koike, S., Komarov, I., Konorov, I., Krivokuca, S., Krüger, H., Kuhr, T., Kühn, W., Kumar, M., Kumar, R., Kun, W., Kvasnička, P., La Licata, C., Lacasta, C., Lalwani, K., Lanceri, L., Lange, J. S., Lautenbach, K., Lee, J. Y., Lee, S. C., Leis, U., Leitl, P., Levit, D., Libby, J., Liemann, G., Liu, Z., Lueck, T., Lütticke, F., Macharski, L., Mammini, P., Mariñas, C., Martini, A., Mayekar, S. N., Mccarney, S., Mohanty, G. B., Morii, T., Moser, H. G., Moya, D., Mueller, F. J., Müller, F., Münchow, D., Nakamura, K. R., Natkaniec, Z., Niebuhr, C., Ninkovic, J., Onuki, Y., Ostrowicz, W., Packheiser, U., Paladino, A., Paoloni, E., Park, H., Paschen, B., Paul, S., Peric, I., Poblotzki, F., Prasanth, K., Profeti, A., Rabusov, A., Rashevskaya, I., Rao, K. K., Reiter, S. P., P. K., Resmi, Richter, R., Ritter, M., Ritzert, M., Rizzo, G., Rozanska, M., Rummel, S., Sahoo, D., Sanchez, J. G., Sasaki, J., Sato, N., Scavino, B., Schaller, G., Schnecke, M., Schopper, F., Schreeck, H., Schultschik, S., Schwanda, C., Schwenker, B., Sedlmeyer, R., Sfienti, C., Simon, F., Skambraks, S., Soloviev, Y., Spruck, B., Stever, R., Stolzenberg, U., Stypula, J., Suzuki, J., Tafelmayer, E., Takahashi, M., Tanaka, S., Tanigawa, H., Taylor, G. N., Thalmeier, R., Tsuboyama, T., Urquijo, P., Vila, I., Virto, A. L., Vitale, L., Vogt, S., Vos, M., Wang, C., Watanuki, S., Watanabe, M., Watson, I. J., Webb, J., Wermes, N., Wessel, C., Wiechczynski, J., Wieduwilt, P., Williams, S., Windel, H., Ye, H., Yin, H., Zani, L., and Zhao, J.

Subjects
Nuclear and High Energy Physics, Physics::Instrumentation and Detectors, Silicon sensor, Phase (waves), Computer Science::Computational Geometry, 7. Clean energy, 01 natural sciences, law.invention, Nuclear physics, Belle II, Data acquisition, Pixel detector, Strip detector, Vertex detector, Instrumentation, law, 0103 physical sciences, Collider, Nuclear and High Energy Physic, Physics, Interconnection, Pixel, 010308 nuclear & particles physics, Detector, data acquisition, pixel detector, silicon sensor, strip detector, vertex detector, Upgrade, High Energy Physics::Experiment, Focus (optics)
Abstract

Belle II DEPFET, PXD, and SVD Collaborations: et al., The Belle II experiment comes with a substantial upgrade of the Belle detector and will operate at the SuperKEKB energy-asymmetric ee collider with energies tuned to ϒ(4S) resonance s=10.588 GeV. The accelerator has successfully completed the first phase of commissioning in 2016 and the first electron–positron collisions in Belle II took place in April 2018. Belle II features a newly designed silicon vertex detector based on DEPFET pixel and double-sided strip layers. Currently, a subset of the vertex detector is installed (Phase 2 of the experiment). Installation of the full detector (Phase 3) will be completed by the end of 2018. This paper describes the Phase 2 arrangement of the Belle II silicon vertex detector, with focus on the interconnection of detectors and their integration with the software framework of Belle II. Alignment issues are discussed based on detector simulations and first acquired data., This work is supported by MSCA-RISE, European Union project JENNIFER (EU grant n. 644294), MEXT, Japan, WPI, and JSPS (Japan); ARC (Australia); BMWFW (Austria); MSMT, Czech Republic, GAUK 404316 (Czech Republic); AIDA-2020 (Germany); DAE, India and DST (India); INFN (Italy); NRF-2016K1A3A7A09005605 and RSRI (Korea); MNiSW (Poland); Federal Ministry of Education and Research (BMBF, Germany); and MINECO, Spain grant FPA2015-71292-C2-1-P (Spain).

Published
2019
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13. Simulation of the Belle II silicon vertex detector

Author

Kaleta, M., primary, Adamczyk, K., additional, Aggarwal, L., additional, Aihara, H., additional, Aziz, T., additional, Bacher, S., additional, Bahinipati, S., additional, Batignani, G., additional, Baudot, J., additional, Behera, P.K., additional, Bettarini, S., additional, Bilka, T., additional, Bozek, A., additional, Buchsteiner, F., additional, Casarosa, G., additional, Corona, L., additional, Czank, T., additional, Das, S.B., additional, Dujany, G., additional, Finck, C., additional, Forti, F., additional, Friedl, M., additional, Gabrielli, A., additional, Ganiev, E., additional, Gobbo, B., additional, Halder, S., additional, Hara, K., additional, Hazra, S., additional, Higuchi, T., additional, Irmler, C., additional, Ishikawa, A., additional, Jeon, H.B., additional, Jin, Y., additional, Joo, C., additional, Kaliyar, A.B., additional, Kandra, J., additional, Kang, K.H., additional, Kapusta, P., additional, Kodyš, P., additional, Kohriki, T., additional, Kumar, M., additional, Kumar, R., additional, La Licata, C., additional, Lalwani, K., additional, Leboucher, R., additional, Lee, S.C., additional, Libby, J., additional, Martel, L., additional, Massaccesi, L., additional, Mayekar, S.N., additional, Mohanty, G.B., additional, Morii, T., additional, Nakamura, K.R., additional, Natkaniec, Z., additional, Onuki, Y., additional, Ostrowicz, W., additional, Paladino, A., additional, Paoloni, E., additional, Park, H., additional, Polat, L., additional, Rao, K.K., additional, Ripp-Baudot, I., additional, Rizzo, G., additional, Sahoo, D., additional, Schwanda, C., additional, Serrano, J., additional, Suzuki, J., additional, Tanaka, S., additional, Tanigawa, H., additional, Thalmeier, R., additional, Tiwary, R., additional, Tsuboyama, T., additional, Uematsu, Y., additional, Verbycka, O., additional, Vitale, L., additional, Wan, K., additional, Wang, Z., additional, Webb, J., additional, Wiechczynski, J., additional, Yin, H., additional, and Zani, L., additional

Published
2022
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14. The Silicon Vertex Detector of the Belle II experiment

Author

Uematsu, Y., primary, Adamczyk, K., additional, Aggarwal, L., additional, Aihara, H., additional, Aziz, T., additional, Bacher, S., additional, Bahinipati, S., additional, Batignani, G., additional, Baudot, J., additional, Behera, P.K., additional, Bettarini, S., additional, Bilka, T., additional, Bozek, A., additional, Buchsteiner, F., additional, Casarosa, G., additional, Corona, L., additional, Czank, T., additional, Das, S.B., additional, Dujany, G., additional, Finck, C., additional, Forti, F., additional, Friedl, M., additional, Gabrielli, A., additional, Ganiev, E., additional, Gobbo, B., additional, Halder, S., additional, Hara, K., additional, Hazra, S., additional, Higuchi, T., additional, Irmler, C., additional, Ishikawa, A., additional, Jeon, H.B., additional, Jin, Y., additional, Joo, C., additional, Kaleta, M., additional, Kaliyar, A.B., additional, Kandra, J., additional, Kang, K.H., additional, Kapusta, P., additional, Kodyš, P., additional, Kohriki, T., additional, Kumar, M., additional, Kumar, R., additional, Licata, C. La, additional, Lalwani, K., additional, Leboucher, R., additional, Lee, S.C., additional, Libby, J., additional, Martel, L., additional, Massaccesi, L., additional, Mayekar, S.N., additional, Mohanty, G.B., additional, Morii, T., additional, Nakamura, K.R., additional, Natkaniec, Z., additional, Onuki, Y., additional, Ostrowicz, W., additional, Paladino, A., additional, Paoloni, E., additional, Park, H., additional, Polat, L., additional, Rao, K.K., additional, Ripp-Baudot, I., additional, Rizzo, G., additional, Sahoo, D., additional, Schwanda, C., additional, Serrano, J., additional, Suzuki, J., additional, Tanaka, S., additional, Tanigawa, H., additional, Thalmeier, R., additional, Tiwary, R., additional, Tsuboyama, T., additional, Verbycka, O., additional, Vitale, L., additional, Wan, K., additional, Wang, Z., additional, Webb, J., additional, Wiechczynski, J., additional, Yin, H., additional, and Zani, L., additional

Published
2022
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15. Measurement of the cluster position resolution of the Belle II Silicon Vertex Detector

Author

Leboucher, R., primary, Adamczyk, K., additional, Aggarwal, L., additional, Aihara, H., additional, Aziz, T., additional, Bacher, S., additional, Bahinipati, S., additional, Batignani, G., additional, Baudot, J., additional, Behera, P.K., additional, Bettarini, S., additional, Bilka, T., additional, Bozek, A., additional, Buchsteiner, F., additional, Casarosa, G., additional, Corona, L., additional, Czank, T., additional, Das, S.B., additional, Dujany, G., additional, Finck, C., additional, Forti, F., additional, Friedl, M., additional, Gabrielli, A., additional, Ganiev, E., additional, Gobbo, B., additional, Halder, S., additional, Hara, K., additional, Hazra, S., additional, Higuchi, T., additional, Irmler, C., additional, Ishikawa, A., additional, Jeon, H.B., additional, Jin, Y., additional, Joo, C., additional, Kaleta, M., additional, Kaliyar, A.B., additional, Kandra, J., additional, Kang, K.H., additional, Kapusta, P., additional, Kodyš, P., additional, Kohriki, T., additional, Kumar, M., additional, Kumar, R., additional, La Licata, C., additional, Lalwani, K., additional, Lee, S.C., additional, Libby, J., additional, Martel, L., additional, Massaccesi, L., additional, Mayekar, S.N., additional, Mohanty, G.B., additional, Morii, T., additional, Nakamura, K.R., additional, Natkaniec, Z., additional, Onuki, Y., additional, Ostrowicz, W., additional, Paladino, A., additional, Paoloni, E., additional, Park, H., additional, Polat, L., additional, Rao, K.K., additional, Ripp-Baudot, I., additional, Rizzo, G., additional, Sahoo, D., additional, Schwanda, C., additional, Serrano, J., additional, Suzuki, J., additional, Tanaka, S., additional, Tanigawa, H., additional, Thalmeier, R., additional, Tiwary, R., additional, Tsuboyama, T., additional, Uematsu, Y., additional, Verbycka, O., additional, Vitale, L., additional, Wan, K., additional, Wang, Z., additional, Webb, J., additional, Wiechczynski, J., additional, Yin, H., additional, and Zani, L., additional

Published
2022
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16. Impact of adaptive image receive coil technology for liver MR imaging at 3.0 Tesla: Intraindividual comparison with use of conventional coil

Author

Fukui, Hideyuki, primary, Onishi, Hiromitsu, additional, Nakamoto, Atsushi, additional, Wakayama, Tetsuya, additional, Ota, Takashi, additional, Tsuboyama, Takahiro, additional, Yano, Keigo, additional, Tarewaki, Hiroyuki, additional, Koyama, Yoshihiro, additional, Tatsumi, Mitsuaki, additional, and Tomiyama, Noriyuki, additional

Published
2022
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19. Theoretical study of chloro-α,β,γ,δ-tetraphenylporphyrinato cobalt(III) dimer reaction: A reaction path to form π cation radicals

Author

Kiyoko Yamamoto, Yuji Kohno, Sei Tsuboyama, and Kazuki Mori

Subjects
Reaction mechanism, 010304 chemical physics, Dimer, Radical, General Physics and Astronomy, Reaction intermediate, 010402 general chemistry, 01 natural sciences, Porphyrin, 0104 chemical sciences, Paramagnetism, chemistry.chemical_compound, Crystallography, chemistry, 0103 physical sciences, Proton NMR, Density functional theory, Physical and Theoretical Chemistry
Abstract

Chloro-α,β,γ,δ-tetraphenylporphyrinato-cobalt(III) (Co(III)TPPCl) is a five-coordinate Co complex ([Co(III)(N)4Cl]) having square-pyramidal structure with chlorine atom at the apex. The compound is diamagnetic. Its 1H NMR spectra in inert solvents show unusual signal broadening at higher temperatures. This was attributed to the partial transformation of the complex to paramagnetic species. To elucidate this specific phenomenon, we proposed a dimer reaction mechanism based on density functional theory calculations with M06-2X/segmented all-electron Gaussian (for Co atom) and 6-31G(d, p) (for C, H, N, Cl atoms) basis sets. The porphyrin dimer, [Co(III)TPPCl]2 (S = 0), is assumed as the important reaction intermediate. The optimized geometry of the dimer is stable compared to two optimized monomers (S = 0) by 22.27 kcal mol−1, but is unstable compared to one Co(III)TPPCl2 (S = 1/2) and one Co(II)TPP (S = 1/2) by 0.95 kcal mol−1. Using the vibrational frequencies from the geometry optimization, the sum of Co(III)TPPCl2 and Co(II)TPP species, the so-called π cation radicals, is the overwhelming majority in the theoretical product distribution at 298.15 K and 1 atm. The dimer reaction can produce the paramagnetic species with a potential energy barrier of 1.65 kcal mol−1.

Published
2019
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20. Development of a monolithic pixel sensor based on SOI technology for the ILC vertex detector

Author

Shun Ono, Taohan Li, Miho Yamada, Yasuo Arai, Toru Tsuboyama, Manabu Togawa, A. Ishikawa, Ikuo Kurachi, Kazuhiko Hara, and Yoichi Ikegami

Subjects
Physics, Nuclear and High Energy Physics, Pixel, International Linear Collider, Comparator, Physics::Instrumentation and Detectors, 010308 nuclear & particles physics, business.industry, Detector, Silicon on insulator, 01 natural sciences, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Optics, 0103 physical sciences, Physics::Accelerator Physics, High Energy Physics::Experiment, Fermilab, Timestamp, business, Instrumentation, Beam (structure)
Abstract

SOI detector SOFIST is a pixel sensor optimized for the International Linear Collider vertex detector. SOFIST stores both position and timing information of charged particles. Our aim is to achieve 3 μ m single-point resolution with a 20 × 20 μ m 2 pixel. The first prototype sensor SOFIST Ver.1 was evaluated with a 120 GeV proton beam at the FermiLab Test Beam Facility. The position resolution was about 1.3 μ m . We are currently evaluating the next version of sensor, SOFIST Ver.2, which has an in-pixel comparator and timestamp.

Published
2019
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21. Radiation hardness of silicon-on-insulator pixel devices

Author

Shikie Iwanami, Miho Yamada, Ikuo Kurachi, Yoichi Ikegami, Toshinobu Miyoshi, Kazuhiko Hara, Shunsuke Honda, Wataru Aoyagi, Yasuo Arai, Toru Tsuboyama, and Daisuke Sekigawa

Subjects
010302 applied physics, Physics, Nuclear and High Energy Physics, Pixel, business.industry, Silicon on insulator, Insulator (electricity), 01 natural sciences, CMOS, Ionization, 0103 physical sciences, Optoelectronics, Wafer, business, Instrumentation, Radiation hardening
Abstract

Silicon-on-Insulator (SOI) CMOS is an attractive technology because of pixel sensor applications for its inherent advantages such as superior isolation of each FET by the surrounding insulator. We have been developing SOI pixel devices since 2005 using the FD-SOI technology and noticed that the insulator layers impose significant sensitivity to the total ionization dose (TID) effect. Research activities in the last ten years to improve radiation hardness are reviewed, such as introduction of buried wells and double SOI wafers.

Published
2019
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22. R&D status of SOI-based pixel detector with 3D stacking readout

Author

Miho Yamada, Yoichi Ikegami, Kazuhiko Hara, Masayuki Ikebe, Shun Ono, Yasuo Arai, Makoto Motoyoshi, Manabu Togawa, A. Ishikawa, Ikuo Kurachi, and Toru Tsuboyama

Subjects
Physics, Nuclear and High Energy Physics, Hardware_MEMORYSTRUCTURES, International Linear Collider, Pixel, 010308 nuclear & particles physics, business.industry, Electrical engineering, Stacking, Silicon on insulator, Integrated circuit design, Chip, 01 natural sciences, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, 0103 physical sciences, Vertex detector, business, Instrumentation, Technology CAD
Abstract

SOFIST4 is an SOI pixel sensor designed for the International Linear Collider (ILC) vertex detector. In order to satisfy the requirements of the ILC vertex detector, the chip consists of three-stage hit-charge and hit-time memories in each 20 μ m × 20 μ m pixel with 3D integration technology. The SOFIST4 chip was submitted for an MPW run in 2017, and 3D integration will be performed in 2018. In this article, the design of the SOFIST4 chip is first described. Then the 3D integration and 3D CAD technology are explained.

Published
2019
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25. Weak hip flexor strength predicts progression of functional capacity decline due to locomotor system dysfunction in community-dwelling older adults: A longitudinal cohort study

Author

50212220, 50203104, Ikezoe, Tome, Tsuboyama, Tadao, Tabara, Yasuharu, Matsuda, Fumihiko, Ichihashi, Noriaki, 50212220, 50203104, Ikezoe, Tome, Tsuboyama, Tadao, Tabara, Yasuharu, Matsuda, Fumihiko, and Ichihashi, Noriaki

Abstract

Purpose: It is critical to determine the risk factors for activities of daily living (ADL) disability caused by locomotor dysfunction. However, no longitudinal study has investigated the association between disability due to locomotive dysfunction and multidimensional factors. Therefore, we investigated the relationship between the progression of functional capacity decline due to locomotive dysfunction and multiple physical functions among older adults in a longitudinal study. Methods: The participants comprised of 433 community-dwelling older adults. Physical function was assessed at baseline, which included handgrip strength, maximal isometric strength of hip flexion, hip extension, hip abduction, knee extension, toe flexion (index for muscle strength), the 5-time chair-stand test (index for muscle power), the one-legged stance and timed ‘‘Up & Go’’ tests (index for balance function), the 30-s stair test (index for muscle endurance), and range of motion (ROM) (an index of joint condition). Functional capacity decline due to locomotive dysfunction was assessed using the 25-question Geriatric Locomotive Function Scale (GLFS-25) before and after a 12-month period. Based on changes in the GLFS-25 score compared with baseline, the non-decline and decline groups were operationally defined. Logistic regression analyses with the groups as the dependent variable and physical function as independent variables were performed. Results: Of the 433 participants, 189 (43.6%) were included in the decline group. Logistic regression analysis revealed hip flexor strength as a primary determinant in the progression of functional capacity decline. Conclusion: These results suggest that among physical functions, hip flexor strength influences the progression of disability resulting from locomotive dysfunction in older adults.

Published
2021

26. Simulation of the Belle II silicon vertex detector

Author

M. Kaleta, K. Adamczyk, L. Aggarwal, H. Aihara, T. Aziz, S. Bacher, S. Bahinipati, G. Batignani, J. Baudot, P.K. Behera, S. Bettarini, T. Bilka, A. Bozek, F. Buchsteiner, G. Casarosa, L. Corona, T. Czank, S.B. Das, G. Dujany, C. Finck, F. Forti, M. Friedl, A. Gabrielli, E. Ganiev, B. Gobbo, S. Halder, K. Hara, S. Hazra, T. Higuchi, C. Irmler, A. Ishikawa, H.B. Jeon, Y. Jin, C. Joo, A.B. Kaliyar, J. Kandra, K.H. Kang, P. Kapusta, P. Kodyš, T. Kohriki, M. Kumar, R. Kumar, C. La Licata, K. Lalwani, R. Leboucher, S.C. Lee, J. Libby, L. Martel, L. Massaccesi, S.N. Mayekar, G.B. Mohanty, T. Morii, K.R. Nakamura, Z. Natkaniec, Y. Onuki, W. Ostrowicz, A. Paladino, E. Paoloni, H. Park, L. Polat, K.K. Rao, I. Ripp-Baudot, G. Rizzo, D. Sahoo, C. Schwanda, J. Serrano, J. Suzuki, S. Tanaka, H. Tanigawa, R. Thalmeier, R. Tiwary, T. Tsuboyama, Y. Uematsu, O. Verbycka, L. Vitale, K. Wan, Z. Wang, J. Webb, J. Wiechczynski, H. Yin, L. Zani, Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), and Belle-II SVD

Subjects
Tracking detectors, Nuclear and High Energy Physics, vertex detector, Belle II, semiconductor detector: microstrip, Detector simulation, BELLE, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], numerical calculations, programming, Instrumentation, performance, Silicon strip detectors
Abstract

International audience; Belle II is the next generation B Factory experiment operating at the SuperKEKB accelerator complex at KEK in Tsukuba, Japan. It is expected to collect 50 ab−1 of data, with a target instantaneous luminosity of 6.5 × 1035 cm−2s−1, which is about 30 times larger than its predecessor, Belle. In view of the ever increasing Belle II data sample, accurate simulation of the detector is growing in importance. This poses a challenging task of compromising between the realistic modeling of the response of individual detector components and reasonable performance in terms of CPU time of the simulation. In this paper we describe the simulation of the silicon vertex detector, its performance against collision data and optimization.

Published
2022
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27. Impact of adaptive image receive coil technology for liver MR imaging at 3.0 Tesla: Intraindividual comparison with use of conventional coil

Author

Hideyuki Fukui, Hiromitsu Onishi, Atsushi Nakamoto, Tetsuya Wakayama, Takashi Ota, Takahiro Tsuboyama, Keigo Yano, Hiroyuki Tarewaki, Yoshihiro Koyama, Mitsuaki Tatsumi, and Noriyuki Tomiyama

Subjects
Technology, Liver Neoplasms, Humans, Radiology, Nuclear Medicine and imaging, General Medicine, Image Enhancement, Magnetic Resonance Imaging, Retrospective Studies
Abstract

A newly developed Adaptive Image Receive (AIR) coil is designed to be more flexible to conform to the human body habitus, and may improve image quality by reducing the distance between the coil element and the imaging subject. This study evaluated the AIR coil's usefulness for liver MR imaging at 3.0 T in comparison with that of a conventional coil retrospectively.The study population comprised 50 consecutive patients, who underwent follow-up liver MR examinations with a 3.0-T MR system using both an AIR coil and a conventional coil to evaluate hepatocellular carcinoma. Three-dimensional fat-suppressed T1-weighted gradient-echo images before and after injection of an MRI contrast agent, T2-weighted single-shot fast spin-echo (SSFSE) images, and diffusion-weighted (DW) images obtained with the AIR coil were compared with corresponding images obtained with the conventional coil. One radiologist measured signal-to-noise ratios (SNRs), while two other radiologists used a 3-point scale to independently assess subjective image noise, artifacts, signal uniformity, and overall image quality.SNRs for the AIR coil were significantly higher than those for the conventional coil (P .05). Subjective image noise for the AIR coil on pre- and postcontrast T1-weighted and DW images was lower than for the conventional coil for both readers (P .05). Overall image quality on pre- and postcontrast T1-weighted and DW images for the AIR coil was better than that for the conventional coil for at least one reader (P .05).In comparison with the conventional coil, AIR coil improved SNR and image quality of liver MR imaging.

Published
2022
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28. Food and nutrition assistance activities at emergency shelters and survivors’ homes after the Great East Japan earthquake, and longitudinal changes in vulnerable groups needing special assistance

Author

Nobuyo Tsuboyama-Kasaoka, Sakiko Ueda, and Kazuko Ishikawa-Takata

Subjects
medicine.medical_specialty, Chronic disease, business.industry, Family medicine, Public health, medicine, Questionnaire, Geology, Building and Construction, Geotechnical Engineering and Engineering Geology, business, Safety Research
Abstract

During disasters, some vulnerable individuals are unable to eat the food that is distributed and thus need special assistance. Hence, the aim of this study was to reveal what kinds of nutrition assistance are provided following a disaster, which groups of vulnerable individuals need special nutrition assistance, and at which phase. This cross-sectional survey was using a self-administered postal-based questionnaire. We analyzed data from 435 registered dietitians who had worked in the areas affected by the Great East Japan Earthquake, collected from a questionnaire survey. At emergency shelters, the groups most identified as needing special assistance in phase 0 were infants and children, followed by elderly and then nursing mothers. In phases 2 and 3, the most identified group was elderly, followed by diabetes patients, and then hypertension patients. The much information that dietitians used to identify vulnerable individuals needing special assistance was provided by doctors and public health nurses. At survivors’ homes, the group most identified as needing special nutrition assistance was elderly in all phases. This study showed that the vulnerable groups that need special nutrition assistance differ by phases after disaster. The needs for nutrition assistance were infants and elderly in early stage, and chronic disease patients and elderly in mid-to long-term. Therefore, it is necessary to provide nutrition assistance at the appropriate timing according to priority.

Published
2021
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29. Weak hip flexor strength predicts progression of functional capacity decline due to locomotor system dysfunction in community-dwelling older adults: A longitudinal cohort study

Author

Tadao Tsuboyama, Tome Ikezoe, Yasuharu Tabara, Noriaki Ichihashi, and Fumihiko Matsuda

Subjects
Aging, medicine.medical_specialty, Longitudinal study, Health (social science), Activities of daily living, Isometric exercise, Physical function, Logistic regression, Physical medicine and rehabilitation, Activities of Daily Living, medicine, Humans, Longitudinal Studies, Muscle Strength, Aged, Balance (ability), Hand Strength, business.industry, Balance function, Muscle strength, Independent Living, Geriatrics and Gerontology, Locomotive dysfunction, business, Range of motion, Gerontology
Abstract

Purpose It is critical to determine the risk factors for activities of daily living (ADL) disability caused by locomotor dysfunction. However, no longitudinal study has investigated the association between disability due to locomotive dysfunction and multidimensional factors. Therefore, we investigated the relationship between the progression of functional capacity decline due to locomotive dysfunction and multiple physical functions among older adults in a longitudinal study. Methods The participants comprised of 433 community-dwelling older adults. Physical function was assessed at baseline, which included handgrip strength, maximal isometric strength of hip flexion, hip extension, hip abduction, knee extension, toe flexion (index for muscle strength), the 5-time chair–stand test (index for muscle power), the one-legged stance and timed ‘‘Up & Go’’ tests (index for balance function), the 30-s stair test (index for muscle endurance), and range of motion (ROM) (an index of joint condition). Functional capacity decline due to locomotive dysfunction was assessed using the 25-question Geriatric Locomotive Function Scale (GLFS-25) before and after a 12-month period. Based on changes in the GLFS-25 score compared with baseline, the non-decline and decline groups were operationally defined. Logistic regression analyses with the groups as the dependent variable and physical function as independent variables were performed. Results Of the 433 participants, 189 (43.6%) were included in the decline group. Logistic regression analysis revealed hip flexor strength as a primary determinant in the progression of functional capacity decline. Conclusion These results suggest that among physical functions, hip flexor strength influences the progression of disability resulting from locomotive dysfunction in older adults.

Published
2021
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31. Beam background study for the Belle II Silicon Vertex Detector

Author

Tanigawa, H., primary, Adamczyk, K., additional, Aihara, H., additional, Aziz, T., additional, Bacher, S., additional, Bahinipati, S., additional, Batignani, G., additional, Baudot, J., additional, Behera, P.K., additional, Bettarini, S., additional, Bilka, T., additional, Bozek, A., additional, Buchsteiner, F., additional, Casarosa, G., additional, Červenkov, D., additional, Chen, Y.Q., additional, Corona, L., additional, Czank, T., additional, Das, S.B., additional, Dash, N., additional, de Marino, G., additional, Doležal, Z., additional, Dujany, G., additional, Forti, F., additional, Friedl, M., additional, Ganiev, E., additional, Gobbo, B., additional, Halder, S., additional, Hara, K., additional, Hazra, S., additional, Higuchi, T., additional, Irmler, C., additional, Ishikawa, A., additional, Jeon, H.B., additional, Joo, C., additional, Kaleta, M., additional, Kaliyar, A.B., additional, Kandra, J., additional, Kang, K.H., additional, Kapusta, P., additional, Kodyš, P., additional, Kohriki, T., additional, Kumar, M., additional, Kumar, R., additional, Kvasnička, P., additional, Licata, C. La, additional, Lalwani, K., additional, Lanceri, L., additional, Lee, S.C., additional, Li, Y.B., additional, Libby, J., additional, Lueck, T., additional, Maity, S., additional, Mayekar, S.N., additional, Mohanty, G.B., additional, Grimaldo, J.A. Mora, additional, Morii, T., additional, Nakamura, K.R., additional, Nakayama, H., additional, Natkaniec, Z., additional, Onuki, Y., additional, Ostrowicz, W., additional, Paladino, A., additional, Paoloni, E., additional, Park, H., additional, Rao, K.K., additional, Ripp-Baudot, I., additional, Rizzo, G., additional, Rout, N., additional, Sahoo, D., additional, Santelj, L., additional, Sato, N., additional, Schwanda, C., additional, Suzuki, J., additional, Tanaka, S., additional, Thalmeier, R., additional, Tsuboyama, T., additional, Uematsu, Y., additional, Vahsen, S.E., additional, Verbycka, O., additional, Vitale, L., additional, Wan, K., additional, Watanuki, S., additional, Webb, J., additional, Wiechczynski, J., additional, Yin, H., additional, Zani, L., additional, and Zhang, T., additional

Published
2020
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33. Development of monolithic SOI pixel sensors capable of fine measurements of space and time

Author

Murayama, Hitoshi, primary, Hara, Kazuhiko, additional, Yamauchi, Hiroki, additional, Abe, Ryuhei, additional, Iwanami, Shikie, additional, Watanabe, Kevin, additional, Okada, Yui, additional, Tsuboyama, Toru, additional, Arai, Yasuo, additional, Miyoshi, Toshinobu, additional, Kurachi, Ikuo, additional, Haba, Junji, additional, Togawa, Manabu, additional, Ikegami, Yoichi, additional, Nishimura, Ryutaro, additional, Ishikawa, Akimasa, additional, Ono, Shun, additional, Li, Taohan, additional, and Yamada, Miho, additional

Published
2020
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36. Performance of the Belle II Silicon Vertex Detector

Author

Tanigawa, H., primary, Adamczyk, K., additional, Aihara, H., additional, Aziz, T., additional, Bacher, S., additional, Bahinipati, S., additional, Batignani, G., additional, Baudot, J., additional, Behera, P.K., additional, Bettarini, S., additional, Bilka, T., additional, Bozek, A., additional, Buchsteiner, F., additional, Casarosa, G., additional, Červenkov, D., additional, Chen, Y.Q., additional, Corona, L., additional, Czank, T., additional, Das, S.B., additional, Dash, N., additional, de Marino, G., additional, Doležal, Z., additional, Dujany, G., additional, Forti, F., additional, Friedl, M., additional, Ganiev, E., additional, Gobbo, B., additional, Halder, S., additional, Hara, K., additional, Hazra, S., additional, Higuchi, T., additional, Irmler, C., additional, Ishikawa, A., additional, Jeon, H.B., additional, Joo, C., additional, Kaleta, M., additional, Kaliyar, A.B., additional, Kandra, J., additional, Kang, K.H., additional, Kapusta, P., additional, Kodyš, P., additional, Kohriki, T., additional, Kumar, M., additional, Kumar, R., additional, Kvasnička, P., additional, La Licata, C., additional, Lalwani, K., additional, Lanceri, L., additional, Lee, S.C., additional, Li, Y.B., additional, Libby, J., additional, Lueck, T., additional, Maity, S., additional, Mayekar, S.N., additional, Mohanty, G.B., additional, Grimaldo, J.A. Mora, additional, Morii, T., additional, Nakamura, K.R., additional, Natkaniec, Z., additional, Onuki, Y., additional, Ostrowicz, W., additional, Paladino, A., additional, Paoloni, E., additional, Park, H., additional, Rao, K.K., additional, Ripp-Baudot, I., additional, Rizzo, G., additional, Rout, N., additional, Sahoo, D., additional, Sato, N., additional, Schwanda, C., additional, Suzuki, J., additional, Tanaka, S., additional, Thalmeier, R., additional, Tsuboyama, T., additional, Uematsu, Y., additional, Verbycka, O., additional, Vitale, L., additional, Wan, K., additional, Watanuki, S., additional, Webb, J., additional, Wiechczynski, J., additional, Yin, H., additional, Zani, L., additional, and Zhang, T., additional

Published
2020
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41. Run and slow control system of the Belle II silicon vertex detector

Author

Irmler, C., primary, Aihara, H., additional, Aziz, T., additional, Bacher, S., additional, Bahinipati, S., additional, Barberio, E., additional, Baroncelli, Ti., additional, Baroncelli, To., additional, Basith, A.K., additional, Batignani, G., additional, Bauer, A., additional, Behera, P.K., additional, Bertacchi, V., additional, Bettarini, S., additional, Bhuyan, B., additional, Bilka, T., additional, Bosi, F., additional, Bosisio, L., additional, Bozek, A., additional, Buchsteiner, F., additional, Caria, G., additional, Casarosa, G., additional, Ceccanti, M., additional, Červenkov, D., additional, Czank, T., additional, Dash, N., additional, De Nuccio, M., additional, Doležal, Z., additional, Forti, F., additional, Friedl, M., additional, Gobbo, B., additional, Grimaldo, J.A.M., additional, Hara, K., additional, Higuchi, T., additional, Ishikawa, A., additional, Jeon, H.B., additional, Joo, C., additional, Kaleta, M., additional, Kandra, J., additional, Kang, K.H., additional, Kodyš, P., additional, Kohriki, T., additional, Komarov, I., additional, Kumar, M., additional, Kumar, R., additional, Kvasnička, P., additional, La Licata, C., additional, Lalwani, K., additional, Lanceri, L., additional, Lee, J.Y., additional, Lee, S.C., additional, Li, Y., additional, Libby, J., additional, Lueck, T., additional, Mammini, P., additional, Martini, A., additional, Mayekar, S.N., additional, Mohanty, G.B., additional, Morii, T., additional, Nakamura, K.R., additional, Natkaniec, Z., additional, Onuki, Y., additional, Ostrowicz, W., additional, Paladino, A., additional, Paoloni, E., additional, Park, H., additional, Prasanth, K., additional, Profeti, A., additional, Rao, K.K., additional, Rashevskaya, I., additional, Resmi, P.K., additional, Rizzo, G., additional, Rozanska, M., additional, Sahoo, D., additional, Sasaki, J., additional, Sato, N., additional, Schultschik, S., additional, Schwanda, C., additional, Stypula, J., additional, Suzuki, J., additional, Tanaka, S., additional, Tanigawa, H., additional, Taylor, G.N., additional, Thalmeier, R., additional, Tsuboyama, T., additional, Urquijo, P., additional, Vitale, L., additional, Wan, K., additional, Watanabe, M., additional, Watanuki, S., additional, Watson, I.J., additional, Webb, J., additional, Wiechczynski, J., additional, Williams, S., additional, Yin, H., additional, and Zani, L., additional

Published
2020
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42. Commissioning of the Belle II Silicon Vertex Detector

Author

Casarosa, G., primary, Aihara, H., additional, Aziz, T., additional, Bacher, S., additional, Bahinipati, S., additional, Barberio, E., additional, Baroncelli, Ti., additional, Baroncelli, To., additional, Basith, A.K., additional, Batignani, G., additional, Bauer, A., additional, Behera, P.K., additional, Bertacchi, V., additional, Bettarini, S., additional, Bhuyan, B., additional, Bilka, T., additional, Bosi, F., additional, Bosisio, L., additional, Bozek, A., additional, Buchsteiner, F., additional, Caria, G., additional, Ceccanti, M., additional, Červenkov, D., additional, Corona, L., additional, Czank, T., additional, Dash, N., additional, De Nuccio, M., additional, Doležal, Z., additional, Forti, F., additional, Friedl, M., additional, Gobbo, B., additional, Grimaldo, J.A.M., additional, Halder, S., additional, Hara, K., additional, Higuchi, T., additional, Irmler, C., additional, Ishikawa, A., additional, Jeon, H.B., additional, Joo, C., additional, Kaleta, M., additional, Kandra, J., additional, Kang, K.H., additional, Kodyš, P., additional, Kohriki, T., additional, Komarov, I., additional, Kumar, M., additional, Kumar, R., additional, Kvasnička, P., additional, La Licata, C., additional, Lalwani, K., additional, Lanceri, L., additional, Lee, J.Y., additional, Lee, S.C., additional, Li, Y., additional, Libby, J., additional, Lueck, T., additional, Mammini, P., additional, Martini, A., additional, Mayekar, S.N., additional, Mohanty, G.B., additional, Morii, T., additional, Nakamura, K.R., additional, Natkaniec, Z., additional, Onuki, Y., additional, Ostrowicz, W., additional, Paladino, A., additional, Paoloni, E., additional, Park, H., additional, Prasanth, K., additional, Profeti, A., additional, Rao, K.K., additional, Rashevskaya, I., additional, Resmi, P.K., additional, Rizzo, G., additional, Rozanska, M., additional, Sahoo, D., additional, Sasaki, J., additional, Sato, N., additional, Schultschik, S., additional, Schwanda, C., additional, Stypula, J., additional, Suzuki, J., additional, Tanaka, S., additional, Tanigawa, H., additional, Taylor, G.N., additional, Thalmeier, R., additional, Tsuboyama, T., additional, Urquijo, P., additional, Vitale, L., additional, Wan, K., additional, Watanabe, M., additional, Watanuki, S., additional, Watson, I.J., additional, Webb, J., additional, Wiechczynski, J., additional, Williams, S., additional, Yin, H., additional, and Zani, L., additional

Published
2020
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43. Series production testing and commissioning of the Belle II SVD readout system

Author

Thalmeier, R., primary, Aihara, H., additional, Aziz, T., additional, Bacher, S., additional, Bahinipati, S., additional, Barberio, E., additional, Baroncelli, Ti., additional, Baroncelli, To., additional, Basith, A.K., additional, Batignani, G., additional, Bauer, A., additional, Behera, P.K., additional, Bertacchi, V., additional, Bettarini, S., additional, Bhuyan, B., additional, Bilka, T., additional, Bosi, F., additional, Bosisio, L., additional, Bozek, A., additional, Buchsteiner, F., additional, Caria, G., additional, Casarosa, G., additional, Ceccanti, M., additional, Červenkov, D., additional, Czank, T., additional, Dash, N., additional, De Nuccio, M., additional, Doležal, Z., additional, Forti, F., additional, Friedl, M., additional, Gobbo, B., additional, Grimaldo, J.A.M., additional, Hara, K., additional, Higuchi, T., additional, Irmler, C., additional, Ishikawa, A., additional, Jeon, H.B., additional, Joo, C., additional, Kaleta, M., additional, Kandra, J., additional, Kang, K.H., additional, Kodyš, P., additional, Kohriki, T., additional, Komarov, I., additional, Kumar, M., additional, Kumar, R., additional, Kvasnička, P., additional, La Licata, C., additional, Lalwani, K., additional, Lanceri, L., additional, Lee, J.Y., additional, Lee, S.C., additional, Li, Y., additional, Libby, J., additional, Lueck, T., additional, Mammini, P., additional, Martini, A., additional, Mayekar, S.N., additional, Mohanty, G.B., additional, Morii, T., additional, Nakamura, K.R., additional, Natkaniec, Z., additional, Onuki, Y., additional, Ostrowicz, W., additional, Paladino, A., additional, Paoloni, E., additional, Park, H., additional, Prasanth, K., additional, Profeti, A., additional, Rao, K.K., additional, Rashevskaya, I., additional, Resmi, P.K., additional, Rizzo, G., additional, Rozanska, M., additional, Sahoo, D., additional, Sasaki, J., additional, Sato, N., additional, Schultschik, S., additional, Schwanda, C., additional, Stypula, J., additional, Suzuki, J., additional, Tanaka, S., additional, Tanigawa, H., additional, Taylor, G.N., additional, Tsuboyama, T., additional, Urquijo, P., additional, Vitale, L., additional, Wan, K., additional, Watanabe, M., additional, Watanuki, S., additional, Watson, I.J., additional, Webb, J., additional, Wiechczynski, J., additional, Williams, S., additional, Yin, H., additional, and Zani, L., additional

Published
2020
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44. Subclinical seizures detected on intracranial EEG: Patient characteristics and impact on surgical outcome in a single pediatric epilepsy surgery center

Author

Bo Zhang, Melissa Tsuboyama, Chellamani Harini, Jeffrey Bolton, and Shanshan Liu

Subjects
Pediatrics, medicine.medical_specialty, Subclinical seizure, Single Center, 03 medical and health sciences, Behavioral Neuroscience, Epilepsy, 0302 clinical medicine, Humans, Medicine, Ictal, Clinical significance, 030212 general & internal medicine, Child, Retrospective Studies, Subclinical infection, integumentary system, business.industry, Electroencephalography, medicine.disease, Confidence interval, Treatment Outcome, nervous system, Neurology, Cohort, Electrocorticography, Epilepsies, Partial, Neurology (clinical), medicine.symptom, business, tissues, 030217 neurology & neurosurgery, Boston
Abstract

Subclinical seizures (SCS) are often captured during intracranial EEG monitoring of pediatric patients with refractory focal epilepsy. However, their clinical significance remains uncertain. We aimed to characterize features associated with SCS and whether their presence impacts epilepsy outcomes post-surgically.A single center retrospective chart review of patients with refractory focal epilepsy who underwent intracranial EEG monitoring at Boston Children's Hospital between 2004 and 2014 was conducted. Patient and seizure characteristics as well as post-operative outcome data were collected.Of the 104 patients included in the study, SCS were recorded in 66 (63%). Fifty-eight had electroclinical seizures (ECS) and SCS (ECS + SCS), and eight patients only had SCS. There were no significant patient characteristics associated with the presence of SCS. One hundred one of the 104 patients (97%) underwent surgical resection after the intracranial EEG monitoring, 53 of which had Engel 1 outcomes (52%). Incomplete resection (OR 0.15, 95% confidence interval (CI) [0.06, 0.40], p 0.001) or presence of temporal plus epilepsy (OR 0.23, 95% CI [0.06, 0.80], p = 0.04) was associated with poor Engel outcomes (Engel 2-4). Presence of SCS was not associated with epilepsy surgical outcomes (p = 0.99).Nearly 2/3 of patients in our study had SCS captured on intracranial EEG monitoring, and arose in overlapping regions with the ictal onset zone of ECS. Completeness of resection remains the most important predictor of seizure outcome, regardless of the presence of SCS. In the absence of ECS during intracranial EEG monitoring, SCS onset zones may provide useful localization information to guide surgical resection plans. This is the largest cohort reported in the literature describing characteristics associated with the presence of SCS and the impact of SCS on pediatric epilepsy surgery outcomes.

Published
2021
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45. Measurement of the Michel parameters (η‾, ξκ ) in the radiative leptonic decay of τ

Author

J. E. Fast, D. Dossett, M. Niiyama, L. Pesántez, V. Trusov, Andrey Sokolov, S. Shinomiya, Byeong Rok Ko, M. Feindt, I. Nakamura, V. Babu, Hui Li, Jingxu Wang, T. Aushev, O. Frost, Z. Suzuki, J. Grygier, J. H. Kang, Y. Miyachi, Hikaru Kawai, M. Belhorn, Benjamin Schwenker, T. Zivko, Y. B. Hsiung, K. Neichi, A. Zupanc, C. C. Zhang, E. Nakano, Antonio Limosani, T. Ferber, D. H. Lee, H. Kakuno, H. Shibuya, M. Watanabe, L. S. Peak, C. Niebuhr, O. Nitoh, K. Nishimura, Chawon Park, A. Loos, J. C. Dingfelder, M. V. Purohit, P. Goldenzweig, Rupert Leitner, V. V. Zhulanov, J. Yamaoka, Xiuwan Li, K. Senyo, S. Eidelman, L. Shang, Ihn Sik Seong, S. Sandilya, K. Ueno, M. Heck, M. J. Kim, T. Kawasaki, P. Pakhlov, W. Ostrowicz, U. Tamponi, Anton Poluektov, T. Schlüter, S. Sugihara, M. Starič, Y. Igarashi, M. Masuda, Dipanwita Dutta, A. Sugiyama, T. Kumita, M. Uchida, X. H. He, D. Cinabro, Philip Lewis, G. B. Mohanty, C. H. Li, Massimo Berger, B. H. Kim, Y. Yook, H. Yamamoto, L. K. Li, V.N. Zhilich, Y. Kato, V. Chobanova, Y. Kuroki, Satoshi Tanaka, D. Liventsev, Y. Arita, I. Jaegle, K. Miyabayashi, M. Lubej, G. Inguglia, I. Badhrees, Y. Koga, E. Nedelkovska, F. Breibeck, H. Park, J. Stypula, C. Kiesling, E. J. White, A. Bozek, P. Chang, G. S. Varner, Y.-T. Lai, K. Suzuki, P. Schonmeier, M. Iwabuchi, R. Mussa, H. B. Jeon, O. Grzymkowska, C. H. Wang, M. Grosse Perdekamp, R. Itoh, Jung-Hyun Kim, S. Wehle, T. Keck, S. Paul, L. Li Gioi, Y. Yamashita, C. Z. Yuan, Yukinori Sato, J. G. Shiu, M. Nayak, T. Bloomfield, A. Ishikawa, A. Drutskoy, S. E. Vahsen, A. Bay, C.-L. Hsu, T. Saito, S. Rummel, T. Matsuda, Yu Nakahama, M. Tanaka, T. Peng, G. Schnell, A. Rostomyan, Tsukasa Aso, P. Wang, H. Miyata, Y. Hoshi, M. Barrett, B. Bhuyan, Y.L. Han, A. Frey, H. Ye, P. Križan, T. Iijima, Jun Sasaki, H. G. Moser, M. Bračko, Y. Iwasaki, B. G. Fulsom, Peter Kodys, W. W. Jacobs, T. E. Browder, Y. J. Kwon, K. Nakamura, Ya-Qiu Jin, P. Hamer, K. Hayasaka, A. Bobrov, H. Hayashii, Hyunyong Kim, O. Schneider, K. Prasanth, M. Imamura, T. Nagamine, K. Trabelsi, P. Katrenko, T. Müller, J. Klucar, K. T. Kim, C. P. Shen, S. Di Carlo, Seok Kim, S. Okuno, B. Shwartz, Jamal Rorie, D. Getzkow, C. B. Van Hulse, I. Adachi, A. Ogawa, K. Negishi, T. Kuhr, D. Z. Besson, E. Ribežl, D. Santel, Phillip Urquijo, N. Sasao, Victoria Zhukova, V. Savinov, M. Danilov, H. Nakayama, D. Y. Kim, R. Gillard, R. Mizuk, Eberhard Widmann, J. F. Strube, Matthew Jones, M. Z. Wang, K. Kinoshita, M. Yamauchi, G. Bonvicini, Y. B. Li, Y. Teramoto, I. Tikhomirov, D. Mohapatra, J. B. Singh, A. Chen, K. Hara, S. K. Choi, Sanmay Ganguly, T. Uchida, Y. Ban, N. Zwahlen, Bruce Yabsley, L. Zhao, M. Heider, M. Rozanska, D. Kotchetkov, Y. Yusa, A. Vinokurova, S. Dubey, Rahul Kumar, J. Libby, R. Louvot, Y. Chao, G. N. Taylor, R. Glattauer, V.E. Shebalin, J. Haba, W. Bartel, S. Nishida, S. Al Said, K. Hoshina, Y. Seino, Y. Onuki, K. Vervink, Z. Drásal, Marko Petrič, M. T. Prim, K. Itagaki, Z. Q. Liu, C. Bookwalter, B. G. Cheon, H. J. Hyun, S. Uozumi, P. Smerkol, Tariq Aziz, X. L. Wang, D. Heffernan, T. Morii, C. Boulahouache, J. Hasenbusch, V. Chekelian, J. Li, V. M. Aulchenko, H. Guo, T.-A. Shibata, T. Horiguchi, Y. Ono, S. Koblitz, Seema Bahinipati, Y. Choi, H. Takeichi, K. J. Nath, S. Uno, C. Schwanda, P. Krokovny, M. T. Hedges, Samo Stanič, L.M. Zhang, E. Kurihara, A.E. Bondar, P.A. Lukin, T. Nakano, K. Dutta, A. Garmash, Daniel Greenwald, M. Takizawa, B. Reisert, Y. Sakai, J. Rauch, B. K. Pal, E. L. Barberio, M. Shapkin, Noritaka Shimizu, T. Hara, L. Santelj, J. Dalseno, Robin Wedd, K. M. Williams, V. Bansal, K. Belous, A. M. Bakich, S. Korpar, Jolanta Brodzicka, John Yelton, T. Ohshima, Z. Doležal, K. Chilikin, Y. J. Kim, N. Dash, S. Iwata, H. Ozaki, H. Nakano, C. Ng, K. H. Kang, K. Cho, K. Inami, M. Sumihama, A. Heller, M. D. Peters, Motoki Iwasaki, Y. Ushiroda, N. Taniguchi, Y. M. Goh, S. H. Lee, K. Prothmann, R. Pestotnik, N. Gabyshev, D. Červenkov, A. Abdesselam, M. Steder, M. E. Sevior, I. S. Lee, D. Matvienko, Y. Miyazaki, R. Sinha, P. K. Behera, Yasushi Nagasaka, B. Kronenbitter, Sumio Yamada, E. Kato, M. Leitgab, Tao Luo, K. Tanida, F. Tenchini, T. Sumiyoshi, A. Bala, D. Epifanov, Soumya D. Mohanty, C. Pulvermacher, Martin Ritter, Dmytro Levit, Z. Natkaniec, S. L. Blyth, T. Sanuki, Shigeki Hirose, K. K. Joo, Hirokazu Miyake, R. Seidl, Y. Guan, E. Solovieva, Norihito Muramatsu, M. Huschle, K. Sakai, Y. Watanabe, S. K. Kim, A.L. Sibidanov, H. Kichimi, M. C. Chang, K. S. Park, V. Bhardwaj, T. K. Pedlar, T. Tsuboyama, H. Palka, L. E. Piilonen, G. Pakhlova, J. Wiechczynski, R. Kulasiri, S. U. Kataoka, S. Yashchenko, A. Moll, S. L. Olsen, D. Joffe, T. Julius, Po-Hsun Chen, R. Chistov, A. Vossen, O. Seon, Frank Simon, D. Semmler, Y. Unno, K. F. Chen, R. Ayad, T. Nozaki, S. Uehara, M. N. Wagner, Peter Kvasnicka, A. B. Kaliyar, Sunmin Ryu, C. W. Park, E. Won, C. Oswald, H. Atmacan, P. Vanhoefer, E. Panzenböck, B. Golob, M. Schram, N. K. Nisar, H. K. Moon, J. S. Lange, M. Ziegler, K. Adamczyk, Y. Soloviev, W. S. Hou, K. Arinstein, Y. Mikami, Alexei Kuzmin, V. Vorobyev, Nagao Kobayashi, Y. F. Liu, C. Kleinwort, Z. P. Zhang, H. Sahoo, Tara Nanut, T. Uglov, Yoji Hasegawa, S. Y. Suzuki, Richard T. Kouzes, K. Sumisawa, D. M. Asner, S. Himori, Kevin Varvell, A. Matyja, Jason Crnkovic, T. Mori, H. Aihara, Y. Usov, Jyoti Prakash Biswal, C. Liu, H. Nakazawa, A. J. Schwartz, H. Farhat, J. B. Kim, T. Higuchi, S. Ogawa, V. Gaur, Y. S. Sohn, Ferdinando Giordano, M. Nakao, E. Waheed, S. McOnie, J. MacNaughton, and P. Kapusta

Subjects
Physics, Nuclear and High Energy Physics, Particle physics, 010308 nuclear & particles physics, Maximum likelihood, Electron–positron annihilation, 01 natural sciences, law.invention, Nuclear physics, KEKB, law, 0103 physical sciences, Radiative transfer, Michel parameters, Statistical analysis, 010306 general physics, Collider, Lepton
Abstract

We present the first measurement of the Michel parameters η ‾ and ξκ in the radiative leptonic decay of the τ lepton using 703 fb-1 of data collected with the Belle detector at the KEKB e + e − collider. The Michel parameters are measured by an unbinned maximum likelihood fit to the kinematic information of e + e − → τ + τ − → ( π + π 0 ν ‾ ) ( l − ν ν ‾ γ ) ( l = e or μ ) . The preliminary values of the measured Michel parameters are η ‾ = − 2.0 ± 1.5 ± 0.8 and ξ κ = 0.6 ± 0.4 ± 0.2 , where the first error is statistical and the second is systematic.

Published
2017
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46. Development of a pixel sensor with fine space-time resolution based on SOI technology for the ILC vertex detector

Author

Miho Yamada, Manabu Togawa, T. Tsuboyama, Yasuo Arai, T. Mori, Ryoji Tsuji, Shun Ono, and Kazunori Hanagaki

Subjects
010302 applied physics, Physics, Nuclear and High Energy Physics, International Linear Collider, Pixel, Physics::Instrumentation and Detectors, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, Analog-to-digital converter, Hardware_PERFORMANCEANDRELIABILITY, Integrated circuit, Chip, 01 natural sciences, law.invention, Computer Science::Hardware Architecture, CMOS, law, 0103 physical sciences, Hardware_INTEGRATEDCIRCUITS, Electronic engineering, Instrumentation, Image resolution, Electronic circuit
Abstract

We have been developing a new monolithic pixel sensor with silicon-on-insulator (SOI) technology for the International Linear Collider (ILC) vertex detector system. The SOI monolithic pixel detector is realized using standard CMOS circuits fabricated on a fully depleted sensor layer. The new SOI sensor SOFIST can store both the position and timing information of charged particles in each 20×20 μm 2 pixel. The position resolution is further improved by the position weighted with the charges spread to multiple pixels. The pixel also records the hit timing with an embedded time-stamp circuit. The sensor chip has column-parallel analog-to-digital conversion (ADC) circuits and zero-suppression logic for high-speed data readout. We are designing and evaluating some prototype sensor chips for optimizing and minimizing the pixel circuit.

Published
2017
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47. Compensation for radiation damage of SOI pixel detector via tunneling

Author

Y. Fujita, M. Yamada, R. Nishimura, K. Tauchi, Yoichi Ikegami, Yasuo Arai, Toshinobu Miyoshi, Ryutaro Hamasaki, Ikuo Kurachi, and T. Tsuboyama

Subjects
010302 applied physics, Physics, Nuclear and High Energy Physics, Physics - Instrumentation and Detectors, Physics::Instrumentation and Detectors, 010308 nuclear & particles physics, business.industry, Detector, FOS: Physical sciences, Silicon on insulator, High voltage, Instrumentation and Detectors (physics.ins-det), Electron, Radiation, Condensed Matter::Mesoscopic Systems and Quantum Hall Effect, 01 natural sciences, Threshold voltage, 0103 physical sciences, MOSFET, Optoelectronics, business, Instrumentation, Quantum tunnelling
Abstract

We are developing monolithic pixel detectors based on SOI technology for high energy physics, X-ray applications and so on.To employ SOI pixel detector on such radiation environments, we have to solve effects of total ionizing dose (TID) for transistors which are enclosed in oxide layer.The holes which are generated and trapped in the oxide layers after irradiation affect characteristics of near-by transistors due to its positive electric field.Annealing and radiation of ultraviolet are not realistic to remove trapped holes for a fabricated detector due to thermal resistance of components and difficulty of handling. We studied compensation of TID effects by tunneling using a high-voltage. For decrease of trapped holes, applied high-voltage to buried p-well which is under oxide layer to inject the electrons into the oxide layer.In this report, recent progress of this study is shown., 10 pages, 14 figures, Proceedings of International Workshop on SOI Pixel Detector (SOIPIX2015), Tohoku University, Sendai, Japan, 3-6, June, 2015. C15-06-03

Published
2016
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48. Glutamatergic Monopolar Interneurons Provide a Novel Pathway of Excitation in the Mouse Retina

Author

Haruhisa Okawa, Sidney P. Kuo, Mrinalini Hoon, Fred Rieke, Sachihiro C. Suzuki, Takeshi Yoshimatsu, Luca Della Santina, Rachel O.L. Wong, and Kotaro Tsuboyama

Subjects
Male, Retinal Ganglion Cells, Genetics and Molecular Biology (all), 0301 basic medicine, Retinal Bipolar Cells, genetic structures, Interneuron, Glutamic Acid, Mice, Transgenic, Medicine (all), Biochemistry, Genetics and Molecular Biology (all), Agricultural and Biological Sciences (all), Biology, Ribbon synapse, Inhibitory postsynaptic potential, Biochemistry, Retinal ganglion, General Biochemistry, Genetics and Molecular Biology, Amacrine cell, Synapse, Mice, 03 medical and health sciences, Glutamatergic, 0302 clinical medicine, medicine, Animals, GABAergic Neurons, Retina, Anatomy, Amacrine Cells, 030104 developmental biology, medicine.anatomical_structure, Female, sense organs, General Agricultural and Biological Sciences, Neuroscience, 030217 neurology & neurosurgery
Abstract

Excitatory and inhibitory neurons in the CNS are distinguished by several features, including morphology, transmitter content, and synapse architecture [1]. Such distinctions are exemplified in the vertebrate retina. Retinal bipolar cells are polarized glutamatergic neurons receiving direct photoreceptor input, whereas amacrine cells are usually monopolar inhibitory interneurons with synapses almost exclusively in the inner retina [2]. Bipolar but not amacrine cell synapses have presynaptic ribbon-like structures at their transmitter release sites. We identified a monopolar interneuron in the mouse retina that resembles amacrine cells morphologically but is glutamatergic and, unexpectedly, makes ribbon synapses. These glutamatergic monopolar interneurons (GluMIs) do not receive direct photoreceptor input, and their light responses are strongly shaped by both ON and OFF pathway-derived inhibitory input. GluMIs contact and make almost as many synapses as type 2 OFF bipolar cells onto OFF-sustained A-type (AOFF-S) retinal ganglion cells (RGCs). However, GluMIs and type 2 OFF bipolar cells possess functionally distinct light-driven responses and may therefore mediate separate components of the excitatory synaptic input to AOFF-S RGCs. The identification of GluMIs thus unveils a novel cellular component of excitatory circuits in the vertebrate retina, underscoring the complexity in defining cell types even in this well-characterized region of the CNS.

Published
2016
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49. Advanced monolithic pixel sensors using SOI technology

Author

S. Mitsui, Miho Yamada, R. Nishimura, Mari Asano, Toshinobu Miyoshi, Kazuhiko Hara, Ryutaro Hamasaki, K. Tauchi, Yoichi Ikegami, Ikuo Kurachi, Shunsuke Honda, Naoshi Tobita, Toru Tsuboyama, Yowichi Fujita, and Yasuo Arai

Subjects
Physics, Nuclear and High Energy Physics, Silicon, Pixel, 010308 nuclear & particles physics, business.industry, Silicon on insulator, chemistry.chemical_element, Hardware_PERFORMANCEANDRELIABILITY, 01 natural sciences, 030218 nuclear medicine & medical imaging, Semiconductor detector, 03 medical and health sciences, 0302 clinical medicine, chemistry, CMOS, Nondestructive testing, 0103 physical sciences, Hardware_INTEGRATEDCIRCUITS, Optoelectronics, Wafer, business, Instrumentation, Hardware_LOGICDESIGN, Electronic circuit
Abstract

We are developing advanced pixel sensors using silicon-on-insulator (SOI) technology. A SOI wafer is used; top silicon is used for electric circuit and bottom silicon is used as a sensor. Target applications are high-energy physics, X-ray astronomy, material science, non-destructive inspection, medical application and so on. We have developed two integration-type pixel sensors, FPIXb and INTPIX7. These sensors were processed on single SOI wafers with various substrates in n- or p-type and double SOI wafers. The development status of double SOI sensors and some up-to-date test results of n-type and p-type SOI sensors are shown.

Published
2016
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50. Review of the evidence on the use of electrical muscle stimulation to treat sarcopenia

Author

Hidenori Arai, Tadao Tsuboyama, Márcio Makoto Nishida, and T. Moritani

Subjects
medicine.medical_specialty, business.industry, Electrical muscle stimulation, medicine.medical_treatment, Glucose uptake, Stimulation, Muscle activation, Oxidative phosphorylation, 030204 cardiovascular system & hematology, Muscle mass, medicine.disease, Muscle hypertrophy, 03 medical and health sciences, 0302 clinical medicine, Physical medicine and rehabilitation, Endocrinology, Internal medicine, Sarcopenia, medicine, Geriatrics and Gerontology, business, Gerontology, 030217 neurology & neurosurgery
Abstract

Electrical muscle stimulation (EMS) has been shown to increase muscle strength and mass, suggesting that it can be used for the treatment of sarcopenia. We herein present a detailed review of the physiological changes induced by EMS. Only human experimental and clinical studies were selected as reference articles for this review. Low-frequency stimulation appears to have greater effects on strengthening, while high frequency favors an increase in muscle mass. EMS also promotes compositional changes of the muscle fibers and improvements in the oxidative enzymatic activity and glucose uptake. Considering that structural changes towards type II muscle fibers and their motor units have an important role in the loss of muscle strength and that the response to muscular training is based on the capacity to increase muscle activation, an intervention protocol using EMS should focus on stimulating type II muscle fibers, rather than on inducing muscle hypertrophy.

Published
2016
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