74 results on '"Stappenbeck, Thaddeus S."'
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2. Microbiota-produced indole metabolites disrupt mitochondrial function and inhibit Cryptosporidium parvum growth
3. 20: LRRK2 ACTIVITY MODULATES PANETH CELL FUNCTION IN CROHN'S DISEASE
4. 963: HIGH FAT DIET-INDUCED MICROVILLUS SHORTENING OF ILEAL ENTEROCYTES IS RESCUED BY ACTIVATION OF PPARα SIGNALING IN MICE
5. 444: MODULATION OF IGA DEGRADATION AND MUCOSAL ADAPTIVE IMMUNITY BY A NOVEL INTESTINAL SYMBIONT
6. Paying attention to minutiae: Strain level differences drive disease etiology
7. HOIL1 regulates group 2 innate lymphoid cell numbers and type 2 inflammation in the small intestine
8. Adaptive differentiation promotes intestinal villus recovery
9. Western diet induces Paneth cell defects through microbiome alterations and farnesoid X receptor and type I interferon activation
10. Enteric helminth coinfection enhances host susceptibility to neurotropic flaviviruses via a tuft cell-IL-4 receptor signaling axis
11. Altered Intestinal ACE2 Levels Are Associated With Inflammation, Severe Disease, and Response to Anti-Cytokine Therapy in Inflammatory Bowel Disease
12. HER2 and APC Mutations Promote Altered Crypt-Villus Morphology and Marked Hyperplasia in the Intestinal Epithelium
13. The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis
14. 272 SHORT-TERM WESTERN DIET DRIVES MICROVILLI ALTERATIONS IN ILEAL ENTEROCYTES THROUGH ACTIVATION OF PPARα SIGNALING IN MICE
15. Long-Term Culture Captures Injury-Repair Cycles of Colonic Stem Cells
16. A Stem-Cell-Derived Platform Enables Complete Cryptosporidium Development In Vitro and Genetic Tractability
17. Su1832 – Inhibition of Intestinal Epithelial Cell Pyroptosis and Associated Mucosal Barrier Defects is a Potential Therapeutic Mechanism of Action for Mesalamine in Ibd
18. Su1826 – Small Intestinal Epithelial Microvilli-Associated Defects Present in a Multi-Center Replication Cohort of Crohn’s Disease Patients
19. Sa1895 – Characterization and Modeling of the Creeping Fat that Occurs in Crohn’s Disease
20. L-WRN conditioned medium for gastrointestinal epithelial stem cell culture shows replicable batch-to-batch activity levels across multiple research teams
21. Microbiome control of innate reactivity
22. Forward Genetics in Cryptosporidium Enabled by Complete in Vitro Development in Stem Cell-Derived Intestinal Epithelium
23. Intestinal Dysmotility Syndromes following Systemic Infection by Flaviviruses
24. Abnormal Small Intestinal Epithelial Microvilli in Patients With Crohn's Disease
25. Temporal Regulation of the Bacterial Metabolite Deoxycholate during Colonic Repair Is Critical for Crypt Regeneration
26. Intestinal Stem Cells Live Off the Fat of the Land
27. Regenerating Islet-Derived 3-Alpha (REG3A) Protects the Intestinal Stem Cell Niche to Control Acute Gastrointestinal Graft-Versus-Host Disease
28. P109 SMOKING NEGATIVELY AFFECTS DISEASE COURSE REGARDLESS OF SMOKING AMOUNT AND MAY BE ASSOCIATED WITH PANETH CELL PHENOTYPE IN JAPANESE CROHN’S DISEASE PATIENTS
29. P063 INTERACTIONS OF GENETIC AND ENVIRONMENTAL FACTORS TRIGGER UNIQUE PPAR-GAMMA SIGNATURE IN PANETH CELLS IN CROHN’S DISEASE SUBJECTS AND RELEVANT MOUSE MODELS
30. P066 INTESTINAL EPITHELIAL MICROVILLI ARE ABNORMAL IN CROHN'S DISEASE
31. Dichotomous Effects of ATG16L1 and LRRK2 in Modulating Paneth Cell Defect in Japanese and North American Crohn's Disease Patients
32. Cigarette Smoking Triggers Paneth Cell Defect in Crohn's Disease Patients and Mice Harboring Susceptibility Allele ATG16L1 T300A
33. RNA-SEQ of Formalin-Fixed, Paraffin-Embedded Intestinal Tissue Identifies an Epithelial Defect in crohn's
34. Paneth Cell Alterations in the Development and Phenotype of Crohn’s Disease
35. A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility
36. The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites
37. The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites
38. Gut-Pancreatic Axis AMPlified in Islets of Langerhans
39. IgG “Detoxes” the Intestinal Mucosa
40. Colitogenic Bacteroides thetaiotaomicron Antigens Access Host Immune Cells in a Sulfatase-Dependent Manner via Outer Membrane Vesicles
41. Type I Interferons Link Viral Infection to Enhanced Epithelial Turnover and Repair
42. Gremlin 1 Identifies a Skeletal Stem Cell with Bone, Cartilage, and Reticular Stromal Potential
43. Disease-Specific Alterations in the Enteric Virome in Inflammatory Bowel Disease
44. Role of viruses and bacteria–virus interactions in autoimmunity
45. Inhibition of Cyclooxygenase-2 Prevents Chronic and Recurrent Cystitis
46. Host–microbe interactions shaping the gastrointestinal environment
47. Tu1165 Evolution of Paneth Cell Phenotype in Crohn's Disease: Implications for Disease Etiopathogenesis
48. 129 Genetic Variation Associated With Paneth Cell Morphological Changes in CD
49. Su1273 Spatial and Temporal Stability of Paneth Cell Phenotypes in Crohn's Disease: Implications for Prognostic Cellular Biomarker Development
50. Genetic Variants Synthesize to Produce Paneth Cell Phenotypes That Define Subtypes of Crohn's Disease
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