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Your search keyword '"Sophie Vichier-Guerre"' showing total 2 results
Start Over Author "Sophie Vichier-Guerre" Publisher elsevier bv
2 results on '"Sophie Vichier-Guerre"'

1. Enantiomeric deoxy-l-nucleotides stabilize a Z-forming DNA decanucleotide

Author

Sophie Vichier-Guerre, Bernard Rayner, and Fanny Santamaria

Subjects
chemistry.chemical_classification, Circular dichroism, chemistry.chemical_compound, Duplex (building), Chemistry, Stereochemistry, Organic Chemistry, Drug Discovery, Nucleic acid, Nucleotide, Enantiomer, Biochemistry, DNA
Abstract

Two contiguous pairs of enantiomeric 2′-deoxy-l-ribonucleotides have been incorporated in a 5-methyl-CG alternating decadeoxyribonucleotide duplex. Data from circular dichroism and UV melting experiments indicate that the two base-pair long enantio-domain within the duplex was able to stabilize a Z-DNA-like conformation.

Published
2000
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