1. Cutaneous paraneoplastic disorders in stomach cancer: Collaboration between oncologically active dermatologists and clinical oncologists
- Author
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Markus Raderer, Ewald Wöll, Michael Hejna, and Philipp Tschandl
- Subjects
medicine.medical_specialty ,Pathology ,Malignancy ,Skin Diseases ,Diagnosis, Differential ,030207 dermatology & venereal diseases ,03 medical and health sciences ,0302 clinical medicine ,stomatognathic system ,Quality of life ,Stomach Neoplasms ,Occult malignancy ,Humans ,Medicine ,Stomach cancer ,Patient Care Team ,business.industry ,Hematology ,medicine.disease ,Dermatology ,stomatognathic diseases ,Oncology ,Skin impairment ,Treatment modality ,030220 oncology & carcinogenesis ,Quality of Life ,Occult cancer ,business ,Skin lesion - Abstract
To our knowledge this is the first systemic review that provides an overview of the cutaneous paraneoplastic syndromes (CPS) (i.e., clinical manifestations, pathomechanisms, and treatment modalities) occurring in stomach cancer. CPS are caused by substances produced by stomach cancer and may precede, coincide with, or follow the diagnosis of this malignancy. More than 20 possible CPS in association with stomach cancer have been identified. CPS mostly compromises the patient's quality of life by skin impairment plus discomfort and are often associated with a dismal prognosis on survival. Studies of these CPS not only in stomach cancer have partially contributed to the understanding of pathomechanism and since CPS may be the presenting sign of an occult cancer, cognizance of their features and clinical implications are of considerable importance. Patients with these syndromes should have an appropriate work-up for a possibly occult malignancy with consecutive successful early treatment.
- Published
- 2016
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