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Your search keyword '"Shuji Ioka"' showing total 2 results
Start Over Author "Shuji Ioka" Publisher elsevier bv
2 results on '"Shuji Ioka"'

1. Development of a luminescence-controllable firefly luciferin analogue using selective enzymatic cyclization

Author

Tsuyoshi Saitoh, Masaya Imoto, Shuji Ioka, Shigeru Nishiyama, and Shojiro Maki

Subjects
0301 basic medicine, Aminoacylase, 030102 biochemistry & molecular biology, Stereochemistry, Thiazoline, Organic Chemistry, Photoprotein, Firefly luciferin, Biochemistry, Luciferin, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, chemistry, Drug Discovery, Moiety, Bioluminescence, Luciferase
Abstract

In this study, a new firefly luciferin analog that can switch firefly bioluminescence (BL) activity from ‘off’ to ‘on’ state was designed and synthesized. BL inactive N -Ac-γ-glutamate luciferin 3 contains an acyclic precursor of the thiazoline moiety. Enzymatic treatment of 3 with aminoacylase resulted in a smooth removal of the acyl protecting group and concomitant cyclization to provide BL active carboluciferin 2 .

Published
2016
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2. Corrigendum to 'Enhancing endogenous adenosine A2A receptor signaling induces slow-wave sleep without affecting body temperature and cardiovascular function' [Neuropharmacology 144 (2019) 122–132]

Author

Yoan Cherasse, Fumihiro Sugiyama, Shinya Fujii, Nobuyuki Murakoshi, Shuji Ioka, Xuzhao Zhou, Feng Duo, Hidetoshi Kumagai, Rujie Qin, Jiang-Fan Chen, Tsuyoshi Saitoh, Hiroshi Nagase, Michael Lazarus, and Mustafa Korkutata

Subjects
Pharmacology, Cellular and Molecular Neuroscience, Chemistry, Adenosine A2A receptor, Endogeny, Neuroscience, Function (biology), Neuropharmacology, Slow-wave sleep
Published
2019
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