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Start Over Author "Sean M Ryan" Publisher elsevier bv
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1. Spironolactone affects cardiovascular and craniofacial development in zebrafish embryos (Danio rerio)

Author

Hannah J, Petty, Jacob E, Barrett, Erin G, Kosmowski, Dandre S, Amos, Sean M, Ryan, Lucas D, Jones, and Christopher S, Lassiter

Subjects
Pharmacology, Health, Toxicology and Mutagenesis, Animals, Embryonic Development, General Medicine, Spironolactone, Diuretics, Toxicology, Zebrafish
Abstract

Spironolactone, a potassium-sparing diuretic and aldosterone antagonist, is a mineralocorticoid hormone commonly prescribed to patients suffering from heart failure, hirsutism, dermatological afflictions, and hypertension. Interestingly, relatively little work has been done on the development of vertebrate embryos after exposure to this compound. Here, we treat zebrafish embryos with spironolactone at 10

Published
2022
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