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2. Smartphone-Based Recognition of Heart Failure by Means of Microelectromechanical Sensors

Author

Haddad, Francois, primary, Saraste, Antti, additional, Santalahti, Kristiina M., additional, Pänkäälä, Mikko, additional, Kaisti, Matti, additional, Kandolin, Riina, additional, Simonen, Piia, additional, Nammas, Wail, additional, Jafarian Dehkordi, Kamal, additional, Koivisto, Tero, additional, Knuuti, Juhani, additional, Mahaffey, Kenneth W., additional, and Blomster, Juuso I., additional

Published
2024
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5. Mannose Receptor (CD206) Targeting with Aluminum Fluoride-18 Labeled Mannosylated Dextran

Author

Andriana, Putri, primary, Fair-Mäkelä, Ruth, additional, Makrypidi, Konstantina, additional, Liljenbäck, Heidi, additional, Kärnä, Salli, additional, Iqbal, Imran, additional, Palani, Senthil, additional, Suni, Aino, additional, Pirmettis, Ioannis, additional, Saraste, Antti, additional, Salmi, Marko, additional, Li, Xiang-Guo, additional, and Roivainen, Anne, additional

Published
2023
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7. Direct intramyocardial injection of VEGF mRNA in patients undergoing coronary artery bypass grafting

Author

Vesa Anttila, Antti Saraste, Juhani Knuuti, Marja Hedman, Pekka Jaakkola, Karl-Ludwig Laugwitz, Markus Krane, Anders Jeppsson, Saara Sillanmäki, Jaya Rosenmeier, Pernilla Zingmark, Anna Rudvik, Pavlo Garkaviy, Christina Watson, Menelas N. Pangalos, Kenneth R. Chien, Regina Fritsche-Danielson, Anna Collén, and Li-Ming Gan

Subjects
Pharmacology, Drug Discovery, Genetics, Molecular Medicine, Molecular Biology
Abstract

Vascular endothelial growth factor A (VEGF-A) has therapeutic cardiovascular effects but delivery challenges have impeded clinical development. We report the first clinical study of naked mRNA encoding VEGF-A (AZD8601) injected into the human heart. EPICCURE (NCT03370887) was a randomized, double-blind study of AZD8601 in patients with left ventricular ejection fraction (LVEF) of 30-50% undergoing elective coronary artery bypass surgery. Thirty epicardial injections of AZD8601 (total 3 mg) or placebo in citrate-buffered saline were targeted to ischemic but viable myocardial regions mapped using quantitative [

Published
2023

10. Myeloperoxidase Inhibition Reverses Biomarker Profiles Associated With Clinical Outcomes in HFpEF

Author

Michaëlsson, Erik, primary, Lund, Lars H., additional, Hage, Camilla, additional, Shah, Sanjiv J., additional, Voors, Adriaan A., additional, Saraste, Antti, additional, Redfors, Björn, additional, Grove, Erik L., additional, Barasa, Anders, additional, Richards, A. Mark, additional, Svedlund, Sara, additional, Lagerström-Fermér, Maria, additional, Gabrielsen, Anders, additional, Garkaviy, Pavlo, additional, Gan, Li-Ming, additional, and Lam, Carolyn S.P., additional

Published
2023
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11. Coronary Volume to Left Ventricular Mass Ratio in Patients With Hypertension

Author

van Rosendael, Sophie E., primary, van Rosendael, Alexander R., additional, Kuneman, Jurrien H., additional, Patel, Manesh R., additional, Nørgaard, Bjarne Linde, additional, Fairbairn, Timothy A., additional, Nieman, Koen, additional, Akasaka, Takashi, additional, Berman, Daniel S., additional, Koweek, Lynne M. Hurwitz, additional, Pontone, Gianluca, additional, Kawasaki, Tomohiro, additional, Sand, Niels Peter Rønnow, additional, Jensen, Jesper M., additional, Amano, Tetsuya, additional, Poon, Michael, additional, Øvrehus, Kristian A., additional, Sonck, Jeroen, additional, Rabbat, Mark G., additional, Rogers, Campbell, additional, Matsuo, Hitoshi, additional, Leipsic, Jonathon A., additional, Marsan, Nina Ajmone, additional, Jukema, J. Wouter, additional, Bax, Jeroen J., additional, Saraste, Antti, additional, and Knuuti, Juhani, additional

Published
2023
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12. Plaque volume, composition, and fraction versus ischemia and outcomes in patients with coronary artery disease

Author

Kuneman, Jurrien H., primary, van den Hoogen, Inge J., additional, Schultz, Jussi, additional, Maaniitty, Teemu, additional, van Rosendael, Alexander R., additional, Kamperidis, Vasileios, additional, de Graaf, Michiel A., additional, Broersen, Alexander, additional, Jukema, J. Wouter, additional, Bax, Jeroen J., additional, Saraste, Antti, additional, and Knuuti, Juhani, additional

Published
2023
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14. Myeloperoxidase Inhibition in Heart Failure With Preserved or Mildly Reduced Ejection Fraction: SATELLITE Trial Results

Author

Lam, CAROLYN S.P., primary, LUND, LARS H., additional, SHAH, SANJIV J., additional, VOORS, ADRIAAN A., additional, ERLINGE, DAVID, additional, SARASTE, ANTTI, additional, PIRAZZI, CARLO, additional, GROVE, ERIK L., additional, BARASA, ANDERS, additional, SCHOU, MORTEN, additional, AZIZ, AHMED, additional, SVEDLUND, SARA, additional, WIJNGAARDEN, JAN VAN, additional, LINDSTEDT, EVA-LOTTE, additional, GUSTAVSSON, ANDREAS, additional, NELANDER, KARIN, additional, GARKAVIY, PAVLO, additional, GAN, LI-MING, additional, and GABRIELSEN, ANDERS, additional

Published
2023
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16. CORONARY FLOW CAPACITY PREDICTS ADVERSE OUTCOME BEYOND STANDARD PERFUSION METRICS IN STABLE CHEST PAIN PATIENTS

Author

Winter, Ruben Willem De, primary, Jukema, Ruurt, additional, Van Diemen, Pepijn, additional, Schumacher, Stefan, additional, Somsen, Yvemarie, additional, van de Hoef, Tim P., additional, van Rossum, Albert, additional, Twisk, Jos, additional, Maaniitty, Teemu, additional, Knuuti, Juhani M., additional, Saraste, Antti, additional, Nap, Alexander, additional, Raijmakers, Pieter, additional, Danad, Ibrahim, additional, and Knaapen, Paul, additional

Published
2023
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18. Implications of the 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Chest Pain Guideline for Cardiovascular Imaging

Author

Ron Blankstein, Leslee J. Shaw, Martha Gulati, Michael K. Atalay, Jeroen Bax, Dennis A. Calnon, Christopher K. Dyke, Maros Ferencik, Jonathan F. Heitner, Timothy D. Henry, Judy Hung, Juhani Knuuti, Jonathan R. Lindner, Lawrence M. Phillips, Subha V. Raman, Sunil V. Rao, Frank J. Rybicki, Antti Saraste, Raymond F. Stainback, Randall C. Thompson, Eric Williamson, Koen Nieman, Jennifer A. Tremmel, Pamela K. Woodard, Marcelo F. Di Carli, and Y.S. Chandrashekhar

Subjects
Radiology, Nuclear Medicine and imaging, Cardiology and Cardiovascular Medicine
Published
2022

19. Direct intramyocardial injection of VEGF mRNA in patients undergoing coronary artery bypass grafting

Author

Anttila, Vesa, primary, Saraste, Antti, additional, Knuuti, Juhani, additional, Hedman, Marja, additional, Jaakkola, Pekka, additional, Laugwitz, Karl-Ludwig, additional, Krane, Markus, additional, Jeppsson, Anders, additional, Sillanmäki, Saara, additional, Rosenmeier, Jaya, additional, Zingmark, Pernilla, additional, Rudvik, Anna, additional, Garkaviy, Pavlo, additional, Watson, Christina, additional, Pangalos, Menelas N., additional, Chien, Kenneth R., additional, Fritsche-Danielson, Regina, additional, Collén, Anna, additional, and Gan, Li-Ming, additional

Published
2022
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20. Extensive and balanced reduction of myocardial blood flow in patients with suspected obstructive coronary artery disease: 15O-water PET study

Author

Juhani Knuuti, Iida Stenström, Teemu Maaniitty, and Antti Saraste

Subjects
medicine.medical_specialty, Ischemia, Hemodynamics, Coronary Artery Disease, 030204 cardiovascular system & hematology, Coronary Angiography, Coronary artery disease, 03 medical and health sciences, Myocardial perfusion imaging, 0302 clinical medicine, Oxygen Radioisotopes, Predictive Value of Tests, Coronary Circulation, Internal medicine, medicine, Humans, 030212 general & internal medicine, medicine.diagnostic_test, business.industry, Myocardial Perfusion Imaging, Water, Blood flow, medicine.disease, Stenosis, medicine.anatomical_structure, Positron-Emission Tomography, Cardiology, Cardiology and Cardiovascular Medicine, business, Perfusion, Artery
Abstract

Detection of obstructive coronary artery disease (CAD) by stress myocardial perfusion imaging (MPI) is conventionally based on relative differences in perfusion. This may lead to either underestimation of the extent of myocardial ischemia, or the ischemia might be completely missed in case of balanced perfusion reduction. Using absolute quantification of myocardial blood flow (MBF) by positron emission tomography (PET), we evaluated how common are extensive and balanced myocardial perfusion abnormalities in symptomatic patients with suspected obstructive CAD.Among 758 consecutive symptomatic patients undergone coronary computed tomography angiography (CTA), 286 patients subsequently underwent quantitative 15O-water adenosine-stress PET MPI to assess the hemodynamic significance of suspected obstructive stenosis. Out of these, 46 (16%) patients had reduced (≤2.3 ml/g/min) absolute stress MBF in all three standard coronary territories (LAD, LCX, RCA). Subsequently, relative stress MBF in each coronary territory was calculated, considering a territory with the highest absolute stress MBF as a reference region. Among the 46 patients, 72% had significant regional heterogeneity in myocardial perfusion (defined as having ≥1 territory with relative stress MBF80%) while the remaining 28% (4.5% of the whole MPI cohort) showed balanced perfusion reduction (all relative MBF values ≥80%).Among symptomatic patients with suspected obstructive stenosis on coronary CTA, quantitative PET revealed that 16% of patients had reduced stress MBF involving all three coronary artery territories, of whom approximately one third showed balanced reduction. Thus, in 4.5% of the patients the perfusion abnormalities could have been missed by conventional relative MPI analysis.

Published
2021

22. Safety and efficacy of the 5-lipoxygenase-activating protein inhibitor AZD5718 in patients with recent myocardial infarction: The phase 2a FLAVOUR study

Author

Prescott, Eva, primary, Angerås, Oskar, additional, Erlinge, David, additional, Grove, Erik L., additional, Hedman, Marja, additional, Jensen, Lisette O., additional, Pernow, John, additional, Saraste, Antti, additional, Åkerblom, Axel, additional, Svedlund, Sara, additional, Rudvik, Anna, additional, Knöchel, Jane, additional, Lindstedt, Eva-Lotte, additional, Garkaviy, Pavlo, additional, Gan, Li-Ming, additional, and Gabrielsen, Anders, additional

Published
2022
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23. TCT-264 Prognostic Value of Coronary Flow Capacity Derived From [15O]H2O Positron Emission Tomography Perfusion Imaging

Author

de Winter, Ruben, primary, Jukema, Ruurt, additional, van Diemen, Pepijn, additional, Schumacher, Stefan, additional, Somsen, Yvemarie, additional, Van de Hoef, Tim, additional, van Rossum, Albert, additional, Twisk, Jos, additional, Maaniitty, Teemu, additional, Knuuti, Juhani, additional, Saraste, Antti, additional, Nap, Alexander, additional, Raijmakers, Pieter, additional, Danad, Ibrahim, additional, and Knaapen, Paul, additional

Published
2022
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27. Radiosynthesis of new PET tracer targeting macrophage mannose receptor

Author

Andriana, Putri, primary, Palani, Senthil, additional, Fair-Mäkelä, Ruth, additional, Makrypidi, Konstantina, additional, Liljenbäck, Heidi, additional, Kärnä, Salli, additional, Salmi, Marko, additional, Pirmettis, Ioannis, additional, Saraste, Antti, additional, Li, Xiang-Guo, additional, and Roivainen, Anne, additional

Published
2022
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28. Implications of the 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Chest Pain Guideline for Cardiovascular Imaging

Author

Blankstein, Ron, primary, Shaw, Leslee J., additional, Gulati, Martha, additional, Atalay, Michael K., additional, Bax, Jeroen, additional, Calnon, Dennis A., additional, Dyke, Christopher K., additional, Ferencik, Maros, additional, Heitner, Jonathan F., additional, Henry, Timothy D., additional, Hung, Judy, additional, Knuuti, Juhani, additional, Lindner, Jonathan R., additional, Phillips, Lawrence M., additional, Raman, Subha V., additional, Rao, Sunil V., additional, Rybicki, Frank J., additional, Saraste, Antti, additional, Stainback, Raymond F., additional, Thompson, Randall C., additional, Williamson, Eric, additional, Nieman, Koen, additional, Tremmel, Jennifer A., additional, Woodard, Pamela K., additional, Di Carli, Marcelo F., additional, and Chandrashekhar, Y.S., additional

Published
2022
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30. FEASIBILITY OF EVALUATING ENDOTHELIAL WALL SHEAR STRESS FROM CORONARY COMPUTED TOMOGRAPHY ANGIOGRAPHY IN PATIENTS WITH CORONARY ARTERY DISEASE

Author

van den Hoogen, Inge J., primary, Schultz, Jussi, additional, Kuneman, Jurrien, additional, De Graaf, Michiel Alexander, additional, Kamperidis, Vasileios, additional, Broersen, Alexander, additional, Jukema, J. Wouter, additional, Sakellarios, Antonis, additional, Nikopoulos, Sotirios, additional, Kyriakidis, Savvas, additional, Naka, Katerina K., additional, Michalis, Lampros K., additional, Fotiadis, Dimitrios I., additional, Maaniitty, Teemu, additional, Saraste, Antti, additional, Bax, Jeroen J., additional, and Knuuti, Juhani M., additional

Published
2022
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31. Effects of dipeptidyl peptidase 4 inhibition on inflammation in atherosclerosis: A 18F-fluorodeoxyglucose study of a mouse model of atherosclerosis and type 2 diabetes

Author

Johanna M. U. Silvola, Pirjo Nuutila, Jenni Virta, Antti Saraste, Juhani Knuuti, Mirva Söderström, Heidi Liljenbäck, Mia Ståhle, Sanna Hellberg, Maria F. Gomez, Jenni Huusko, Seppo Ylä-Herttuala, and Anne Roivainen

Subjects
0301 basic medicine, Fluorodeoxyglucose, medicine.medical_specialty, Aorta, medicine.diagnostic_test, business.industry, Histology, Inflammation, Type 2 diabetes, 030204 cardiovascular system & hematology, Linagliptin, medicine.disease, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Endocrinology, Positron emission tomography, Internal medicine, medicine.artery, medicine, medicine.symptom, Cardiology and Cardiovascular Medicine, business, Dipeptidyl peptidase-4, medicine.drug
Abstract

Background and aims Dipeptidyl peptidase 4 (DPP-4) inhibitors have anti-inflammatory and atheroprotective effects. We evaluated the effects of the DPP-4 inhibitor linagliptin on atherosclerotic plaque and hepatic inflammation using histology and 2-deoxy-2-[18F]-fluoro- d -glucose (18F-FDG), a positron emission tomography tracer of inflammation, in a mouse model of hypercholesterolemia and type 2 diabetes. Methods Igf2/Ldlr−/−Apob100/100 mice were fed a high-fat diet (HFD) for 8 weeks and then randomly allocated to receive HFD (n = 14), or HFD with added linagliptin (n = 15) for additional 12 weeks. Five mice fed a chow diet were studied as an additional control. At the end of the study, glucose tolerance, aortic and liver uptake of 18F-FDG, and histology were studied. Results Mice in linagliptin and HFD groups had similar fasting glucose concentrations, but linagliptin improved glucose tolerance. Aortas of linagliptin and HFD groups showed advanced atherosclerotic plaques with no difference in the mean intima-to-media ratio or number of macrophages in the plaques. Autoradiography showed similar 18F-FDG uptake by atherosclerotic plaques in linagliptin and HFD groups (plaque-to-wall ratio: 1.7 ± 0.25 vs. 1.6 ± 0.21; p = 0.24). In the liver, linagliptin reduced the histologic inflammation score but had no effect on 18F-FDG uptake. Compared with chow diet, uptake of 18F-FDG was similar in the aorta, but higher in the liver after HFD. Conclusions Linagliptin therapy improved glucose tolerance and reduced hepatic inflammation but had no effect on plaque burden or atherosclerotic inflammation, as determined by histology and 18F-FDG uptake, in atherosclerotic mice with type 2 diabetes.

Published
2020

32. Percutaneous left atrial appendage closure in patients with prior intracranial bleeding and thromboembolism

Author

Fausto Biancari, Samuli Jaakkola, Jussi-Pekka Pouru, Juha Lund, Tuija Vasankari, K.E. Juhani Airaksinen, and Antti Saraste

Subjects
Male, Relative risk reduction, Cardiac Catheterization, medicine.medical_specialty, Percutaneous, 030204 cardiovascular system & hematology, 03 medical and health sciences, 0302 clinical medicine, Thromboembolism, Physiology (medical), Atrial Fibrillation, medicine, Humans, Atrial Appendage, Registries, 030212 general & internal medicine, Cardiac Surgical Procedures, Stroke, Contraindication, Aged, Retrospective Studies, Aspirin, business.industry, Atrial fibrillation, medicine.disease, Clopidogrel, Confidence interval, Surgery, Treatment Outcome, Female, Cardiology and Cardiovascular Medicine, business, Intracranial Hemorrhages, Follow-Up Studies, medicine.drug
Abstract

Background Percutaneous left atrial appendage closure (LAAC) is an alternative treatment in atrial fibrillation patients with contraindication to oral anticoagulation. However, patient selection criteria for LAAC are debated. Objective The purpose of this study was to evaluate the outcome after LAAC in patients with prior intracranial bleeding and thromboembolism. Methods Consecutive patients with atrial fibrillation and prior intracranial bleeding who underwent LAAC from February 2009 to August 2018 at the Turku University Hospital, Finland, were included in a prospective registry. Patients were followed through clinical visits and annual phone calls up to 5 years. Results Overall 104 patients (mean age 73 ± 7 years; 30% women; CHA₂DS₂-VASc score 4.7 ± 1.4; HAS-BLED score 3.3 ± 0.9) with atrial fibrillation and prior intracranial bleeding underwent successful LAAC using mainly (n = 102) Amplatzer devices. Median time from intracranial bleeding to LAAC was 7 months, and median follow-up 3.6 years. Antithrombotic treatment was ≤6 months in 71 patients (68%), and 48 patients (46%) received aspirin or clopidogrel alone. The rates of thromboembolism and intracranial bleeding (per 100 patient-years) were 3.4 and 1.9, respectively. In 39 patients with previous thromboembolism, the rate of thromboembolism was 3.6 per 100 patient-years (95% confidence interval 1.5–7.0), yielding a 69% relative risk reduction with respect to predicted risk based on median CHA2DS2-VASc score. Overall, rates of thromboembolism and intracranial bleeding were broadly similar in patients with and those without prior thromboembolism. Conclusion Percutaneous LAAC with minimized antithrombotic treatment was demonstrated to be a valid treatment option in high-risk patients with prior intracranial bleeding and thromboembolism.

Published
2020

33. Quantitative PET Perfusion Imaging

Author

Antti Saraste and Juhani Knuuti

Subjects
business.industry, MEDLINE, Medicine, Coronary flow reserve, Radiology, Nuclear Medicine and imaging, Perfusion scanning, Cardiology and Cardiovascular Medicine, business, Nuclear medicine
Published
2021

35. Radiosynthesis of new PET tracer targeting macrophage mannose receptor

Author

Putri Andriana, Senthil Palani, Ruth Fair-Mäkelä, Konstantina Makrypidi, Heidi Liljenbäck, Salli Kärnä, Marko Salmi, Ioannis Pirmettis, Antti Saraste, Xiang-Guo Li, and Anne Roivainen

Subjects
Cancer Research, Molecular Medicine, Radiology, Nuclear Medicine and imaging
Published
2022

38. Determinants of Myocardial Strain in Experimental Chronic Myocardial Infarction

Author

Juhani Knuuti, Tommi Vähäsilta, Anne Roivainen, Ville-Veikko Hynninen, Antti Saraste, Mika Teräs, Haitham Ballo, Christoffer Stark, Tuula Tolvanen, Marjatta Strandberg, Timo Savunen, Matti Haavisto, Virva Saunavaara, and Miikka Tarkia

Subjects
Male, medicine.medical_specialty, Acoustics and Ultrasonics, Swine, Myocardial Infarction, Biophysics, Speckle tracking echocardiography, 030204 cardiovascular system & hematology, Anterior Descending Coronary Artery, 030218 nuclear medicine & medical imaging, Muscle hypertrophy, 03 medical and health sciences, 0302 clinical medicine, Fibrosis, Internal medicine, Occlusion, Animals, Medicine, ta318, Radiology, Nuclear Medicine and imaging, Radiological and Ultrasound Technology, medicine.diagnostic_test, business.industry, Area under the curve, ta3141, Heart, ta3121, medicine.disease, Disease Models, Animal, Echocardiography, Positron emission tomography, Chronic Disease, Cardiology, business, Radial stress
Abstract

We evaluated the relationships between regional myocardial strain measured by speckle tracking echocardiography and viability, fibrosis, hypertrophy and oxygen consumption in the infarcted or remote myocardium in a pig model of chronic myocardial infarction (MI). Thirteen farm pigs with surgical occlusion of the left anterior descending coronary artery and five sham-operated pigs were studied 3 mo post-MI. Computed tomography revealed significant left ventricle remodeling. Reduced radial or circumferential strain identified areas of transmural infarction (area under the curve: 0.82 and 0.79, respectively). In the remote non-infarcted area, radial strain correlated inversely with the amount of fibrosis (r = –0.66, p = 0.04) and myocyte hypertrophy (r = –0.68, p = 0.03). Radial strain rate inversely correlated with myocardial resting oxygen consumption assessed with 11C-labeled acetate positron emission tomography (r = –0.71, p = 0.006). In conclusion, myocardial strain and strain rate reflect fibrosis, hypertrophy and oxygen consumption of the remote areas after MI.

Published
2019

41. Generalizability of HFA-PEFF and H2FPEF Diagnostic Algorithms and Associations With Heart Failure Indices and Proteomic Biomarkers: Insights From PROMIS-HFpEF

Author

Faxen, U.L., primary, Venkateshvaran, Ashwin, additional, Shah, Sanjiv J., additional, Lam, Carolyn S.P., additional, Svedlund, Sara, additional, Saraste, Antti, additional, Beussink-Nelson, Lauren, additional, Lagerstrom Fermer, Maria, additional, Gan, Li-Ming, additional, Hage, Camilla, additional, and Lund, Lars H., additional

Published
2021
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42. FEASIBILITY OF EVALUATING ENDOTHELIAL WALL SHEAR STRESS FROM CORONARY COMPUTED TOMOGRAPHY ANGIOGRAPHY IN PATIENTS WITH CORONARY ARTERY DISEASE

Author

Inge J. van den Hoogen, Jussi Schultz, Jurrien Kuneman, Michiel Alexander De Graaf, Vasileios Kamperidis, Alexander Broersen, J. Wouter Jukema, Antonis Sakellarios, Sotirios Nikopoulos, Savvas Kyriakidis, Katerina K. Naka, Lampros K. Michalis, Dimitrios I. Fotiadis, Teemu Maaniitty, Antti Saraste, Jeroen J. Bax, and Juhani M. Knuuti

Subjects
Cardiology and Cardiovascular Medicine
Published
2022

46. EFFICACY, SAFETY AND TOLERABILITY OF THE 5-LIPOXYGENASE-ACTIVATING PROTEIN INHIBITOR AZD5718 IN PATIENTS WITH RECENT MYOCARDIAL INFARCTION: A PHASE 2A STUDY (FLAVOUR)

Author

Prescott, Eva, primary, Angerås, Oskar, additional, Erlinge, David, additional, Grove, Erik L., additional, Hedman, Marja, additional, Jensen, Lisette, additional, Pernow, John, additional, Saraste, Antti, additional, Åkerblom, Axel, additional, Rudvik, Anna, additional, Lindstedt, Eva-Lotte, additional, Garkaviy, Pavlo, additional, Gan, Li-Ming, additional, and Gabrielsen, Anders, additional

Published
2021
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48. Incorporating Coronary Calcification Into Pre-Test Assessment of the Likelihood of Coronary Artery Disease

Author

Winther, Simon, primary, Schmidt, Samuel Emil, additional, Mayrhofer, Thomas, additional, Bøtker, Hans Erik, additional, Hoffmann, Udo, additional, Douglas, Pamela S., additional, Wijns, William, additional, Bax, Jeroen, additional, Nissen, Louise, additional, Lynggaard, Vibeke, additional, Christiansen, Jens Juel, additional, Saraste, Antti, additional, Bøttcher, Morten, additional, and Knuuti, Juhani, additional

Published
2020
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49. Association of Coronary Microvascular Dysfunction With Heart Failure Hospitalizations and Mortality in Heart Failure With Preserved Ejection Fraction: A Follow-up in the PROMIS-HFpEF Study

Author

Hage, Camilla, primary, Svedlund, Sara, additional, Saraste, Antti, additional, Faxén, Ulrika Ljung, additional, Benson, Lina, additional, Fermer, Maria Lagerstrom, additional, Gan, Li-Ming, additional, Shah, Sanjiv J., additional, Lam, Carolyn S.P., additional, and Lund, Lars H., additional

Published
2020
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50. Design and rationale of FLAVOUR: A phase IIa efficacy study of the 5-lipoxygenase activating protein antagonist AZD5718 in patients with recent myocardial infarction

Author

Prescott, Eva, primary, Pernow, John, additional, Saraste, Antti, additional, Åkerblom, Axel, additional, Angerås, Oskar, additional, Erlinge, David, additional, Grove, Erik L., additional, Hedman, Marja, additional, Jensen, Lisette O., additional, Svedlund, Sara, additional, Kjaer, Magnus, additional, Lagerström-Fermér, Maria, additional, and Gan, Li-Ming, additional

Published
2020
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