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1. Mario Rigoni Stern: Memories of the Russian Campaign (1943-1945)

Author

Angelo Falvino

Subjects
Alpini, World War II, Eastern Front, media_common.quotation_subject, Mario Rigoni Stern, Art history, Spanish Civil War, Stern, Asiago, Feeling, General Materials Science, Ideology, Sociology, Social science, Don, media_common
Abstract

This research looks at the works of Mario Rigoni Stern and focuses on the literary features of the writer's works, so closely related with the tragic experience of war and with events in his area of origin: the Asiago plateau at the foot of the Alps. The other dominant fact was nostalgia for the native mountain village. The war, its causes, ideological conflicts are depicted together with the scenes showing real life of people and their feelings.

Published
2014
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3. Corrigendum to “How reliable is assessment of true vocal cord-arytenoid unit mobility in patients affected by laryngeal cancer? a multi-institutional study on 366 patients from the ARYFIX collaborative group” [Oral Oncol. 152C (2024) 106744]

Author

Ferrari, M., primary, Mularoni, F., additional, Taboni, S., additional, Crosetti, E., additional, Pessina, C., additional, Carobbio, A.L.C., additional, Montalto, N., additional, Marchi, F., additional, Vural, A., additional, Paderno, A., additional, Caprioli, S., additional, Gaudioso, P., additional, Fermi, M., additional, Rigoni, F., additional, Saccardo, T., additional, Contro, G., additional, Ruaro, A., additional, Lo Manto, A., additional, Varago, C., additional, Baldovin, M., additional, Bandolin, L., additional, Filauro, M., additional, Sampieri, C., additional, Missale, F., additional, Ioppi, A., additional, Carta, F., additional, Ramanzin, M., additional, Ravanelli, M., additional, Maiolo, V., additional, Bertotto, I., additional, Del Bon, F., additional, Lancini, D., additional, Mariani, C., additional, Marrosu, V., additional, Tatti, M., additional, Cağlı, S., additional, Yüce, I., additional, Gündoğ, M., additional, Dogan, S., additional, Anile, G., additional, Gottardi, C., additional, Busato, F., additional, Vallin, A., additional, Gennarini, F., additional, Bossi, P., additional, Ghi, M.G., additional, Lionello, M., additional, Zanoletti, E., additional, Marioni, G., additional, Maroldi, R., additional, Mattioli, F., additional, Puxeddu, R., additional, Bertolin, A., additional, Presutti, L., additional, Piazza, C., additional, Succo, G., additional, Peretti, G., additional, and Nicolai, P., additional

Published
2024
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4. Dopamine Neuron Activity and Stress Signaling as Links Between Social Hierarchy and Psychopathology Vulnerability

Author

Battivelli, Dorian, primary, Vernochet, Cécile, additional, Conabady, Estelle, additional, Nguyen, Claire, additional, Zayed, Abdallah, additional, Lebel, Ashley, additional, Meirsman, Aura Carole, additional, Messaoudene, Sarah, additional, Fieggen, Alexandre, additional, Dreux, Gautier, additional, Rigoni, Daiana, additional, Le Borgne, Tinaïg, additional, Marti, Fabio, additional, Contesse, Thomas, additional, Barik, Jacques, additional, Tassin, Jean-Pol, additional, Faure, Philippe, additional, Parnaudeau, Sébastien, additional, and Tronche, François, additional

Published
2024
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6. Lessons learned after three years of SPIDER operation and the first MITICA integrated tests

Author

Marcuzzi, D, Toigo, V, Boldrin, M, Chitarin, G, Dal Bello, S, Grando, L, Luchetta, A, Pasqualotto, R, Pavei, M, Serianni, G, Zanotto, L, Agnello, R, Agostinetti, P, Agostini, M, Aprile, D, Barbisan, M, Battistella, M, Berton, G, Bigi, M, Brombin, M, Candela, V, Candeloro, V, Canton, A, Casagrande, R, Cavallini, C, Cavazzana, R, Cordaro, L, Cruz, N, Dalla Palma, M, Dan, M, De Lorenzi, A, Delogu, R, De Muri, M, De Nardi, M, Denizeau, S, Fadone, M, Fellin, F, Ferro, A, Gaio, E, Gasparrini, C, Gnesotto, F, Jain, P, La Rosa, A, Lopez-Bruna, D, Lorenzini, R, Maistrello, A, Manduchi, G, Manfrin, S, Marconato, N, Mario, I, Martini, G, Milazzo, R, Patton, T, Peruzzo, S, Pilan, N, Pimazzoni, A, Poggi, C, Pomaro, N, Pouradier-Duteil, B, Recchia, M, Rigoni-Garola, A, Rizzetto, D, Rizzolo, A, Santoro, F, Sartori, E, Segalini, B, Shepherd, A, Siragusa, M, Sonato, P, Sottocornola, A, Spada, E, Spagnolo, S, Spolaore, M, Taliercio, C, Tinti, P, Tomsic, P, Trevisan, L, Ugoletti, M, Valente, M, Valisa, M, Veronese, F, Vignando, M, Zaccaria, P, Zagorski, R, Zaniol, B, Zaupa, M, Zuin, M, Cavenago, M, Boilson, D, Rotti, C, Decamps, H, Geli, F, Sharma, A, Veltri, P, Zacks, J, Simon, M, Paolucci, F, Garbuglia, A, Gutierrez, D, Masiello, A, Mico, G, Labate, C, Readman, P, Bragulat, E, Bailly-Maitre, L, Gomez, G, Kouzmenko, G, Albajar, F, Kashiwagi, M, Tobari, H, Kojima, A, Murayama, M, Hatakeyama, S, Oshita, E, Maejima, T, Shibata, N, Yamashita, Y, Watanabe, K, Singh, N, Singh, M, Dhola, H, Fantz, U, Heinemann, B, Wimmer, C, Wunderlich, D, Tsumori, K, Croci, G, Gorini, G, Muraro, A, Rebai, M, Tardocchi, M, Giacomelli, L, Rigamonti, D, Taccogna, F, Bruno, D, Rutigliano, M, Longo, S, Deambrosis, S, Miorin, E, Montagner, F, Tonti, A, Panin, F, Marcuzzi D., Toigo V., Boldrin M., Chitarin G., Dal Bello S., Grando L., Luchetta A., Pasqualotto R., Pavei M., Serianni G., Zanotto L., Agnello R., Agostinetti P., Agostini M., Aprile D., Barbisan M., Battistella M., Berton G., Bigi M., Brombin M., Candela V., Candeloro V., Canton A., Casagrande R., Cavallini C., Cavazzana R., Cordaro L., Cruz N., Dalla Palma M., Dan M., De Lorenzi A., Delogu R., De Muri M., De Nardi M., Denizeau S., Fadone M., Fellin F., Ferro A., Gaio E., Gasparrini C., Gnesotto F., Jain P., La Rosa A., Lopez-Bruna D., Lorenzini R., Maistrello A., Manduchi G., Manfrin S., Marconato N., Mario I., Martini G., Milazzo R., Patton T., Peruzzo S., Pilan N., Pimazzoni A., Poggi C., Pomaro N., Pouradier-Duteil B., Recchia M., Rigoni-Garola A., Rizzetto D., Rizzolo A., Santoro F., Sartori E., Segalini B., Shepherd A., Siragusa M., Sonato P., Sottocornola A., Spada E., Spagnolo S., Spolaore M., Taliercio C., Tinti P., Tomsic P., Trevisan L., Ugoletti M., Valente M., Valisa M., Veronese F., Vignando M., Zaccaria P., Zagorski R., Zaniol B., Zaupa M., Zuin M., Cavenago M., Boilson D., Rotti C., Decamps H., Geli F., Sharma A., Veltri P., Zacks J., Simon M., Paolucci F., Garbuglia A., Gutierrez D., Masiello A., Mico G., Labate C., Readman P., Bragulat E., Bailly-Maitre L., Gomez G., Kouzmenko G., Albajar F., Kashiwagi M., Tobari H., Kojima A., Murayama M., Hatakeyama S., Oshita E., Maejima T., Shibata N., Yamashita Y., Watanabe K., Singh N. P., Singh M. J., Dhola H., Fantz U., Heinemann B., Wimmer C., Wunderlich D., Tsumori K., Croci G., Gorini G., Muraro A., Rebai M., Tardocchi M., Giacomelli L., Rigamonti D., Taccogna F., Bruno D., Rutigliano M., Longo S., Deambrosis S., Miorin E., Montagner F., Tonti A., Panin F., Marcuzzi, D, Toigo, V, Boldrin, M, Chitarin, G, Dal Bello, S, Grando, L, Luchetta, A, Pasqualotto, R, Pavei, M, Serianni, G, Zanotto, L, Agnello, R, Agostinetti, P, Agostini, M, Aprile, D, Barbisan, M, Battistella, M, Berton, G, Bigi, M, Brombin, M, Candela, V, Candeloro, V, Canton, A, Casagrande, R, Cavallini, C, Cavazzana, R, Cordaro, L, Cruz, N, Dalla Palma, M, Dan, M, De Lorenzi, A, Delogu, R, De Muri, M, De Nardi, M, Denizeau, S, Fadone, M, Fellin, F, Ferro, A, Gaio, E, Gasparrini, C, Gnesotto, F, Jain, P, La Rosa, A, Lopez-Bruna, D, Lorenzini, R, Maistrello, A, Manduchi, G, Manfrin, S, Marconato, N, Mario, I, Martini, G, Milazzo, R, Patton, T, Peruzzo, S, Pilan, N, Pimazzoni, A, Poggi, C, Pomaro, N, Pouradier-Duteil, B, Recchia, M, Rigoni-Garola, A, Rizzetto, D, Rizzolo, A, Santoro, F, Sartori, E, Segalini, B, Shepherd, A, Siragusa, M, Sonato, P, Sottocornola, A, Spada, E, Spagnolo, S, Spolaore, M, Taliercio, C, Tinti, P, Tomsic, P, Trevisan, L, Ugoletti, M, Valente, M, Valisa, M, Veronese, F, Vignando, M, Zaccaria, P, Zagorski, R, Zaniol, B, Zaupa, M, Zuin, M, Cavenago, M, Boilson, D, Rotti, C, Decamps, H, Geli, F, Sharma, A, Veltri, P, Zacks, J, Simon, M, Paolucci, F, Garbuglia, A, Gutierrez, D, Masiello, A, Mico, G, Labate, C, Readman, P, Bragulat, E, Bailly-Maitre, L, Gomez, G, Kouzmenko, G, Albajar, F, Kashiwagi, M, Tobari, H, Kojima, A, Murayama, M, Hatakeyama, S, Oshita, E, Maejima, T, Shibata, N, Yamashita, Y, Watanabe, K, Singh, N, Singh, M, Dhola, H, Fantz, U, Heinemann, B, Wimmer, C, Wunderlich, D, Tsumori, K, Croci, G, Gorini, G, Muraro, A, Rebai, M, Tardocchi, M, Giacomelli, L, Rigamonti, D, Taccogna, F, Bruno, D, Rutigliano, M, Longo, S, Deambrosis, S, Miorin, E, Montagner, F, Tonti, A, Panin, F, Marcuzzi D., Toigo V., Boldrin M., Chitarin G., Dal Bello S., Grando L., Luchetta A., Pasqualotto R., Pavei M., Serianni G., Zanotto L., Agnello R., Agostinetti P., Agostini M., Aprile D., Barbisan M., Battistella M., Berton G., Bigi M., Brombin M., Candela V., Candeloro V., Canton A., Casagrande R., Cavallini C., Cavazzana R., Cordaro L., Cruz N., Dalla Palma M., Dan M., De Lorenzi A., Delogu R., De Muri M., De Nardi M., Denizeau S., Fadone M., Fellin F., Ferro A., Gaio E., Gasparrini C., Gnesotto F., Jain P., La Rosa A., Lopez-Bruna D., Lorenzini R., Maistrello A., Manduchi G., Manfrin S., Marconato N., Mario I., Martini G., Milazzo R., Patton T., Peruzzo S., Pilan N., Pimazzoni A., Poggi C., Pomaro N., Pouradier-Duteil B., Recchia M., Rigoni-Garola A., Rizzetto D., Rizzolo A., Santoro F., Sartori E., Segalini B., Shepherd A., Siragusa M., Sonato P., Sottocornola A., Spada E., Spagnolo S., Spolaore M., Taliercio C., Tinti P., Tomsic P., Trevisan L., Ugoletti M., Valente M., Valisa M., Veronese F., Vignando M., Zaccaria P., Zagorski R., Zaniol B., Zaupa M., Zuin M., Cavenago M., Boilson D., Rotti C., Decamps H., Geli F., Sharma A., Veltri P., Zacks J., Simon M., Paolucci F., Garbuglia A., Gutierrez D., Masiello A., Mico G., Labate C., Readman P., Bragulat E., Bailly-Maitre L., Gomez G., Kouzmenko G., Albajar F., Kashiwagi M., Tobari H., Kojima A., Murayama M., Hatakeyama S., Oshita E., Maejima T., Shibata N., Yamashita Y., Watanabe K., Singh N. P., Singh M. J., Dhola H., Fantz U., Heinemann B., Wimmer C., Wunderlich D., Tsumori K., Croci G., Gorini G., Muraro A., Rebai M., Tardocchi M., Giacomelli L., Rigamonti D., Taccogna F., Bruno D., Rutigliano M., Longo S., Deambrosis S., Miorin E., Montagner F., Tonti A., and Panin F.

Abstract

ITER envisages the use of two heating neutral beam injectors plus an optional one as part of the auxiliary heating and current drive system, to reach the desired performances during its various phases of operation. The 16.5 MW expected neutral beam power per injector is several notches higher than worldwide existing facilities. In order to enable such development, a Neutral Beam Test Facility (NBTF) was established at Consorzio RFX, exploiting the synergy of two test beds, called SPIDER and MITICA. SPIDER is dedicated developing and characterizing large efficient negative ion sources at relevant parameters in ITER-like conditions: source and accelerator located in the same vacuum where the beam propagates, immunity to electromagnetic interferences of multiple radio-frequency (RF) antennas, avoidance of RF-induced discharges on the outside of the source. Three years of experiments on SPIDER have addressed to the necessary design modifications to enable full performances. The source is presently under a long shut-down phase to incorporate learnings from the experimental campaign, in particular events/issues occurred during operation, which led to the identification of improvement opportunities/necessities (e.g. RF discharges, local burns, water leaks, other damages, configuration/design upgrades to maximize chances/margin to quest target parameters). Parallelly, developments on MITICA, the full-scale prototype of the ITER Neutral Beam Injector (NBI) featuring a 1 MV accelerator and ion neutralization, are underway including manufacturing of the beam source, accelerator and the beam line components, while power supplies and auxiliary plants, already installed, are under final testing and commissioning. Integration, commissioning and tests of the 1 MV power supplies are essential for this first-of-kind system, unparalleled both in research and industry field. 1.2 MV dc insulating tests of high voltage components were successfully completed. The integrated test to confir

Published
2023

11. Comparative growth performance of backgrounded beef heifers treated with an injectable fixed-dose combination (0.2 mg/kg doramectin + 6.0 mg/kg levamisole hydrochloride) or single-active (0.2 mg/kg ivermectin) endectocide

Author

DeRosa, Andrew A., primary, Holzmer, Susan, additional, Ball, Jase J., additional, Watkins, Landon P., additional, Blanding, Mitchell, additional, Alley, Mark, additional, Short, Thomas H., additional, Bechtol, David T., additional, Waite, Audie R., additional, Rigoni, Elizabeth J., additional, and Tena, Jezaniah K., additional

Published
2023
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19. Evaluation of vaccination coverage in heart failure patients in a tertiary center

Author

Maire, Adrien, primary, Chapet, Nicolas, additional, Aguilhon, Sylvain, additional, Laugier, Marie-Lucie, additional, Laffont-Lozes, Paul, additional, Rigoni, Mélinda, additional, Mathieu, Betty, additional, Audurier, Yohan, additional, Breuker, Cyril, additional, de Barry, Gaëlle, additional, Jalabert, Anne, additional, Leclercq, Florence, additional, Pasquié, Jean-Luc, additional, Roubille, François, additional, and Castet-Nicolas, Audrey, additional

Published
2023
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20. Electrical diagnostics for high voltage tests in MITICA

Author

Patton, T., primary, Aprile, D., additional, Boldrin, M., additional, Chitarin, G., additional, Dan, M., additional, Gobbo, R., additional, Pilan, N., additional, Pomaro, N., additional, Rigoni, A., additional, Valente, M., additional, Zanotto, L., additional, Barbato, P., additional, Fincato, M., additional, Ghiraldelli, R., additional, Lotto, L., additional, Molon, F., additional, and Tollin, M., additional

Published
2023
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23. As built design of the control systems of the ITER full-size beam source SPIDER in the neutral beam test facility - A critical review

Author

Luchetta, A., primary, Taliercio, C., additional, Cruz, N., additional, Martini, G., additional, Manduchi, G., additional, Rigoni, A., additional, Trevisan, L., additional, Paolucci, F., additional, Labate, C., additional, Breda, M., additional, Capobianco, R., additional, Moressa, M., additional, Molon, F., additional, Sartore, A., additional, Simionato, P., additional, Zampiva, E., additional, Barbato, P., additional, Carraro, M., additional, and Migliorato, L., additional

Published
2023
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24. Lessons learned after three years of SPIDER operation and the first MITICA integrated tests

Author

Marcuzzi, D., primary, Toigo, V., additional, Boldrin, M., additional, Chitarin, G., additional, Dal Bello, S., additional, Grando, L., additional, Luchetta, A., additional, Pasqualotto, R., additional, Pavei, M., additional, Serianni, G., additional, Zanotto, L., additional, Agnello, R., additional, Agostinetti, P., additional, Agostini, M., additional, Aprile, D., additional, Barbisan, M., additional, Battistella, M., additional, Berton, G., additional, Bigi, M., additional, Brombin, M., additional, Candela, V., additional, Candeloro, V., additional, Canton, A., additional, Casagrande, R., additional, Cavallini, C., additional, Cavazzana, R., additional, Cordaro, L., additional, Cruz, N., additional, Dalla Palma, M., additional, Dan, M., additional, De Lorenzi, A., additional, Delogu, R., additional, De Muri, M., additional, De Nardi, M., additional, Denizeau, S., additional, Fadone, M., additional, Fellin, F., additional, Ferro, A., additional, Gaio, E., additional, Gasparrini, C., additional, Gnesotto, F., additional, Jain, P., additional, La Rosa, A., additional, Lopez-Bruna, D., additional, Lorenzini, R., additional, Maistrello, A., additional, Manduchi, G., additional, Manfrin, S., additional, Marconato, N., additional, Mario, I., additional, Martini, G., additional, Milazzo, R., additional, Patton, T., additional, Peruzzo, S., additional, Pilan, N., additional, Pimazzoni, A., additional, Poggi, C., additional, Pomaro, N., additional, Pouradier-Duteil, B., additional, Recchia, M., additional, Rigoni-Garola, A., additional, Rizzetto, D., additional, Rizzolo, A., additional, Santoro, F., additional, Sartori, E., additional, Segalini, B., additional, Shepherd, A., additional, Siragusa, M., additional, Sonato, P., additional, Sottocornola, A., additional, Spada, E., additional, Spagnolo, S., additional, Spolaore, M., additional, Taliercio, C., additional, Tinti, P., additional, Tomsič, P., additional, Trevisan, L., additional, Ugoletti, M., additional, Valente, M., additional, Valisa, M., additional, Veronese, F., additional, Vignando, M., additional, Zaccaria, P., additional, Zagorski, R., additional, Zaniol, B., additional, Zaupa, M., additional, Zuin, M., additional, Cavenago, M., additional, Boilson, D., additional, Rotti, C., additional, Decamps, H., additional, Geli, F., additional, Sharma, A., additional, Veltri, P., additional, Zacks, J., additional, Simon, M., additional, Paolucci, F., additional, Garbuglia, A., additional, Gutierrez, D., additional, Masiello, A., additional, Mico, G., additional, Labate, C., additional, Readman, P., additional, Bragulat, E., additional, Bailly-Maitre, L., additional, Gomez, G., additional, Kouzmenko, G., additional, Albajar, F., additional, Kashiwagi, M., additional, Tobari, H., additional, Kojima, A., additional, Murayama, M., additional, Hatakeyama, S., additional, Oshita, E., additional, Maejima, T., additional, Shibata, N., additional, Yamashita, Y., additional, Watanabe, K., additional, Singh, N.P., additional, Singh, M.J., additional, Dhola, H., additional, Fantz, U., additional, Heinemann, B., additional, Wimmer, C., additional, Wünderlich, D., additional, Tsumori, K., additional, Croci, G., additional, Gorini, G., additional, Muraro, A., additional, Rebai, M., additional, Tardocchi, M., additional, Giacomelli, L., additional, Rigamonti, D., additional, Taccogna, F., additional, Bruno, D., additional, Rutigliano, M., additional, Longo, S., additional, Deambrosis, S., additional, Miorin, E., additional, Montagner, F., additional, Tonti, A., additional, and Panin, F., additional

Published
2023
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26. Impact of waitlist time on post-HSCT survival: a cohort study at a hospital in southern Brazil

Author

Silva, Tatiana Schnorr, primary, Horvath, Jaqueline Driemeyer Correia, additional, Pereira, Mariana Pinto, additional, David, Caroline Nespolo de, additional, Vargas, Dora Fraga, additional, Rigoni, Lisandra Della Costa, additional, Sartor, Ivaine Tais Sauthier, additional, Kern, Luciane Beatriz, additional, da Silva, Priscila de Oliveira, additional, Paz, Alessandra Aparecida, additional, Daudt, Liane Esteves, additional, and Astigarraga, Claudia Caceres, additional

Published
2023
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27. Overview on electrical issues faced during the SPIDER experimental campaigns

Author

Maistrello, Alberto, primary, Agostini, Matteo, additional, Bigi, Marco, additional, Brombin, Matteo, additional, Dan, Mattia, additional, Casagrande, Riccardo, additional, De Nardi, Marco, additional, Ferro, Alberto, additional, Gaio, Elena, additional, Jain, Palak, additional, Lunardon, Francesco, additional, Marconato, Nicolò, additional, Marcuzzi, Diego, additional, Recchia, Mauro, additional, Patton, Tommaso, additional, Pavei, Mauro, additional, Santoro, Francesco, additional, Toigo, Vanni, additional, Zanotto, Loris, additional, Barbisan, Marco, additional, Baseggio, Lucio, additional, Bernardi, Marco, additional, Berton, Giovanni, additional, Boldrin, Marco, additional, Dal Bello, Samuele, additional, Fasolo, Daniele, additional, Franchin, Luca, additional, Ghiraldelli, Raffaele, additional, Grando, Luca, additional, Milazzo, Ruggero, additional, Pimazzoni, Antonio, additional, Rigoni, Andrea, additional, Sartori, Emanuele, additional, Serianni, Gianluigi, additional, Shepherd, Alastair, additional, Ugoletti, Margherita, additional, Zaniol, Barbara, additional, Zella, Daniele, additional, Zerbetto, Enrico, additional, Decamps, Hans, additional, Rotti, Chandramouli, additional, and Veltri, Pierluigi, additional

Published
2023
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30. Medical emergencies in dental practice: A nationwide web-based survey of Italian dentists

Author

Varoni, Elena M., primary, Rigoni, Marta, additional, Lodi, Giovanni, additional, Sardella, Andrea, additional, Muti, Paola, additional, Vitello, Antonio, additional, Montebugnoli, Lucio, additional, Polimeni, Antonella, additional, Tommasino, Stella, additional, Iriti, Marcello, additional, Senna, Andrea, additional, Iandolo, Raffaele, additional, Nisio, Alessandro, additional, and Carrassi, Antonio, additional

Published
2023
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32. Anomalous Diffusion in Thin-Film Cu-Zr Nanoglasses

Author

Rigoni, Christian Aaron, primary, Boltynjuk, Evgeniy, additional, Voigt, Hendrik, additional, Rösner, Harald, additional, Tyler, Bonnie, additional, Hahn, Horst, additional, Divinski, Sergiy V., additional, and Wilde, Gerhard, additional

Published
2023
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33. The timing system of the ITER full size neutral beam injector prototype

Author

C. Taliercio, A. Rigoni, Adriano Luchetta, and Gabriele Manduchi

Subjects
Timing systems, Test facility, 010308 nuclear & particles physics, Computer science, Mechanical Engineering, Nuclear engineering, Timing system, Data acquisition, Experimental Devices, MDSplus, 01 natural sciences, Ion source, 010305 fluids & plasmas, Nuclear Energy and Engineering, Neutral beam injector, ITER, Neutral Beam Test Facility, 0103 physical sciences, MITICA timing system, NBTF, General Materials Science, Beam (structure), IEEE1588, Civil and Structural Engineering
Abstract

The ITER Neutral Beam Test Facility (NBTF) is currently under construction at Consorzio RFX, Padova, Italy. The NBTF includes two experimental devices: SPIDER for the study of the ion source and MITICA for the development of the full-size HNB prototype. Even if the two experiments share many architectural aspects in their Control and Data Acquisition System (CODAS), there are nevertheless some significant differences because MITICA must adhere to ITER's directives for plant control design. This paper describes the architecture of the MITICA timing system that represents one of the first examples of integration of IEEE1588 timing functions in fusion research medium-scale experiments. Timing functions are required in MITICA CODAS to: 1) Synchronize data acquisition and assign a timestamp to each data sample; 2) Supervise the generation of events, trigger a reaction of the control system and/or provide enhanced data acquisition in a time window centered on the event occurrence time. The IEEE1588 time synchronization protocol ensures sub-microsecond clock alignment among devices connected via a LAN. Therefore, it has the potential advantage of avoiding direct cabling among the involved actors, being all the synchronization messages exchanged over the LAN. A feature that IEEE1588 does not cover is the management of asynchronous events that may trigger some actions. Asynchronous events may trigger: 1) Enhanced data acquisition (e.g. with a higher sampling speed) during a time window centered on the trigger occurrence time; 2) Real-time response from the control system. While the management of events triggering control actions is under the responsibility of the real- time control system, for events triggering enhanced data acquisition, the "lazy triggers" solution is adopted in MITICA. This solution allows events to be communicated via LAN, compensating the delay in network communication will be compensated by means of circular buffers at the ADC side.

Published
2019
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34. Lessons learned after three years of SPIDER operation and the first MITICA integrated tests

Author

D. Marcuzzi, V. Toigo, M. Boldrin, G. Chitarin, S. Dal Bello, L. Grando, A. Luchetta, R. Pasqualotto, M. Pavei, G. Serianni, L. Zanotto, R. Agnello, P. Agostinetti, M. Agostini, D. Aprile, M. Barbisan, M. Battistella, G. Berton, M. Bigi, M. Brombin, V. Candela, V. Candeloro, A. Canton, R. Casagrande, C. Cavallini, R. Cavazzana, L. Cordaro, N. Cruz, M. Dalla Palma, M. Dan, A. De Lorenzi, R. Delogu, M. De Muri, M. De Nardi, S. Denizeau, M. Fadone, F. Fellin, A. Ferro, E. Gaio, C. Gasparrini, F. Gnesotto, P. Jain, A. La Rosa, D. Lopez-Bruna, R. Lorenzini, A. Maistrello, G. Manduchi, S. Manfrin, N. Marconato, I. Mario, G. Martini, R. Milazzo, T. Patton, S. Peruzzo, N. Pilan, A. Pimazzoni, C. Poggi, N. Pomaro, B. Pouradier-Duteil, M. Recchia, A. Rigoni-Garola, D. Rizzetto, A. Rizzolo, F. Santoro, E. Sartori, B. Segalini, A. Shepherd, M. Siragusa, P. Sonato, A. Sottocornola, E. Spada, S. Spagnolo, M. Spolaore, C. Taliercio, P. Tinti, P. Tomsič, L. Trevisan, M. Ugoletti, M. Valente, M. Valisa, F. Veronese, M. Vignando, P. Zaccaria, R. Zagorski, B. Zaniol, M. Zaupa, M. Zuin, M. Cavenago, D. Boilson, C. Rotti, H. Decamps, F. Geli, A. Sharma, P. Veltri, J. Zacks, M. Simon, F. Paolucci, A. Garbuglia, D. Gutierrez, A. Masiello, G. Mico, C. Labate, P. Readman, E. Bragulat, L. Bailly-Maitre, G. Gomez, G. Kouzmenko, F. Albajar, M. Kashiwagi, H. Tobari, A. Kojima, M. Murayama, S. Hatakeyama, E. Oshita, T. Maejima, N. Shibata, Y. Yamashita, K. Watanabe, N.P. Singh, M.J. Singh, H. Dhola, U. Fantz, B. Heinemann, C. Wimmer, D. Wünderlich, K. Tsumori, G. Croci, G. Gorini, A. Muraro, M. Rebai, M. Tardocchi, L. Giacomelli, D. Rigamonti, F. Taccogna, D. Bruno, M. Rutigliano, S. Longo, S. Deambrosis, E. Miorin, F. Montagner, A. Tonti, F. Panin, Marcuzzi, D, Toigo, V, Boldrin, M, Chitarin, G, Dal Bello, S, Grando, L, Luchetta, A, Pasqualotto, R, Pavei, M, Serianni, G, Zanotto, L, Agnello, R, Agostinetti, P, Agostini, M, Aprile, D, Barbisan, M, Battistella, M, Berton, G, Bigi, M, Brombin, M, Candela, V, Candeloro, V, Canton, A, Casagrande, R, Cavallini, C, Cavazzana, R, Cordaro, L, Cruz, N, Dalla Palma, M, Dan, M, De Lorenzi, A, Delogu, R, De Muri, M, De Nardi, M, Denizeau, S, Fadone, M, Fellin, F, Ferro, A, Gaio, E, Gasparrini, C, Gnesotto, F, Jain, P, La Rosa, A, Lopez-Bruna, D, Lorenzini, R, Maistrello, A, Manduchi, G, Manfrin, S, Marconato, N, Mario, I, Martini, G, Milazzo, R, Patton, T, Peruzzo, S, Pilan, N, Pimazzoni, A, Poggi, C, Pomaro, N, Pouradier-Duteil, B, Recchia, M, Rigoni-Garola, A, Rizzetto, D, Rizzolo, A, Santoro, F, Sartori, E, Segalini, B, Shepherd, A, Siragusa, M, Sonato, P, Sottocornola, A, Spada, E, Spagnolo, S, Spolaore, M, Taliercio, C, Tinti, P, Tomsic, P, Trevisan, L, Ugoletti, M, Valente, M, Valisa, M, Veronese, F, Vignando, M, Zaccaria, P, Zagorski, R, Zaniol, B, Zaupa, M, Zuin, M, Cavenago, M, Boilson, D, Rotti, C, Decamps, H, Geli, F, Sharma, A, Veltri, P, Zacks, J, Simon, M, Paolucci, F, Garbuglia, A, Gutierrez, D, Masiello, A, Mico, G, Labate, C, Readman, P, Bragulat, E, Bailly-Maitre, L, Gomez, G, Kouzmenko, G, Albajar, F, Kashiwagi, M, Tobari, H, Kojima, A, Murayama, M, Hatakeyama, S, Oshita, E, Maejima, T, Shibata, N, Yamashita, Y, Watanabe, K, Singh, N, Singh, M, Dhola, H, Fantz, U, Heinemann, B, Wimmer, C, Wunderlich, D, Tsumori, K, Croci, G, Gorini, G, Muraro, A, Rebai, M, Tardocchi, M, Giacomelli, L, Rigamonti, D, Taccogna, F, Bruno, D, Rutigliano, M, Longo, S, Deambrosis, S, Miorin, E, Montagner, F, Tonti, A, and Panin, F

Subjects
Accelerator Physics (physics.acc-ph), iter, Mechanical Engineering, FOS: Physical sciences, nbtf, neutral beam injector, mitica, Physics - Plasma Physics, Plasma Physics (physics.plasm-ph), Nuclear Energy and Engineering, Physics - Accelerator Physics, General Materials Science, spider, Civil and Structural Engineering
Abstract

ITER envisages the use of two heating neutral beam injectors plus an optional one as part of the auxiliary heating and current drive system, to reach the desired performances during its various phases of operation. The 16.5 MW expected neutral beam power per injector is several notches higher than worldwide existing facilities.In order to enable such development, a Neutral Beam Test Facility (NBTF) was established at Consorzio RFX, exploiting the synergy of two test beds, called SPIDER and MITICA. SPIDER is dedicated developing and char-acterizing large efficient negative ion sources at relevant parameters in ITER-like conditions: source and accel-erator located in the same vacuum where the beam propagates, immunity to electromagnetic interferences of multiple radio-frequency (RF) antennas, avoidance of RF-induced discharges on the outside of the source. Three years of experiments on SPIDER have addressed to the necessary design modifications to enable full perfor-mances. The source is presently under a long shut-down phase to incorporate learnings from the experimental campaign, in particular events/issues occurred during operation, which led to the identification of improvement opportunities/necessities (e.g. RF discharges, local burns, water leaks, other damages, configuration/design upgrades to maximize chances/margin to quest target parameters).Parallelly, developments on MITICA, the full-scale prototype of the ITER Neutral Beam Injector (NBI) featuring a 1 MV accelerator and ion neutralization, are underway including manufacturing of the beam source, accel-erator and the beam line components, while power supplies and auxiliary plants, already installed, are under final testing and commissioning.Integration, commissioning and tests of the 1 MV power supplies are essential for this first-of-kind system, unparalleled both in research and industry field. 1.2 MV dc insulating tests of high voltage components were successfully completed. The integrated test to confirm 1 MV output by combining invertor systems, DC gener-ators and transmission lines extracted errors/accidents in some components. To realize a concrete system for ITER, said events have been addressed and solutions for the repair and the improvement of the system were developed.Hence, NBTF is emerging as a necessary facility, due to the large gap with existing injectors, effectively dedicated to identify issues and find solutions to enable successful ITER NBI operations in a time bound fashion. The lessons learned during the implementation on NBTF and future perspectives are here discussed.

Published
2023
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35. PBX1-directed stem cell transcriptional program drives tumor progression in myeloproliferative neoplasm

Author

Federico Colombo, Marta Ubezio, Emanuela Morenghi, Laura Crisafulli, Sharon Muggeo, Paolo Vezzoni, Clelia Peano, Elena Fontana, Anna Villa, Matteo G. Della Porta, Francesca Ficara, Rosita Rigoni, and Paolo Uva

Subjects
Myeloid, myeloproliferative neoplasm, MPN, Mice, Transgenic, Biology, Biochemistry, Transcriptome, CD61, Neoplasms, Report, Emb, hemic and lymphatic diseases, erythrocytosis, Genetics, medicine, Animals, Humans, RNA-Seq, JAK2V617F, Progenitor cell, Myeloproliferative neoplasm, Mice, Knockout, Myeloproliferative Disorders, Pbx1, Gene Expression Profiling, Pre-B-Cell Leukemia Transcription Factor 1, fungi, food and beverages, Granulocytosis, differentiation, Cell Biology, Hematopoietic Stem Cells, medicine.disease, Gene Expression Regulation, Neoplastic, Disease Models, Animal, Haematopoiesis, medicine.anatomical_structure, HSPC, Tumor progression, Mutation, Disease Progression, Cancer research, Stem cell, Signal Transduction, Developmental Biology
Abstract

Summary PBX1 regulates the balance between self-renewal and differentiation of hematopoietic stem cells and maintains proto-oncogenic transcriptional pathways in early progenitors. Its increased expression was found in myeloproliferative neoplasm (MPN) patients bearing the JAK2V617F mutation. To investigate if PBX1 contributes to MPN, and to explore its potential as therapeutic target, we generated the JP mouse strain, in which the human JAK2 mutation is induced in the absence of PBX1. Typical MPN features, such as thrombocythemia and granulocytosis, did not develop without PBX1, while erythrocytosis, initially displayed by JP mice, gradually resolved over time; splenic myeloid metaplasia and in vitro cytokine independent growth were absent upon PBX1 inactivation. The aberrant transcriptome in stem/progenitor cells from the MPN model was reverted by the absence of PBX1, demonstrating that PBX1 controls part of the molecular pathways deregulated by the JAK2V617F mutation. Modulation of the PBX1-driven transcriptional program might represent a novel therapeutic approach., Graphical abstract, Highlights • In the novel JP mouse, the JAK2V617F MPN-driver mutation is induced without Pbx1 • In JP mice, typical MPN features did not develop or resolved over time • The stem cell gene Pbx1 is a key contributor in establishing and maintaining MPN • Pbx1-dependent pathways may represent novel therapeutic targets for MPN, Ficara and colleagues generated a mouse model in which the human JAK2V617F myeloproliferative neoplasm (MPN) driver mutation is induced in the absence of the transcription factor Pbx1. Typical disease features did not develop or resolved over time, demonstrating that Pbx1 is a key contributor in establishing and maintaining MPN. Pbx1-dependent genes and pathways may represent novel therapeutic targets.

Published
2021
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36. Trust-formation processes in financial advisors: A structural equation model

Author

Caterina Cruciani, Ugo Rigoni, and Gloria Gardenal

Subjects
Finance, Financial advisory, MiFID2, Structural equation modelling, Trust, Trust-formation process, Settore SECS-P/11 - Economia degli Intermediari Finanziari, Economics and Econometrics, business.industry, media_common.quotation_subject, Financial instrument, Maturity (finance), Structural equation modeling, Fiduciary, Settore SECS-P/09 - Finanza Aziendale, Dictator game, Framing (social sciences), Service (economics), Norm (social), business, media_common
Abstract

This paper focuses on the investor-advisor relation, looking at financial advisory as a fiduciary service. Consistently with the economic literature on the Trust Game, we formalize trust between financial advisors and clients as driven by a combination of two traditional motives – a norm to trust and anticipated reciprocation. We use related literature and insights from the recently introduced European Markets in Financial Instruments Directive 2 (MiFID 2) to define an original survey to estimate a structural equation model of trust formation, where trust and its two main motives are described as latent variables. Besides this methodological contribution, we test the validity of the hypothesized structural relation and explore whether specific features of financial advisors are likely to lead to different trust-formation processes. We find that the professional framing (tied versus bank advisors) and the maturity (new entrants versus incumbents) of financial advisors do indeed support different trust-formation processes. We conclude by exploring how these processes may be differently affected by the new regulation and discussing implications for the financial advisory industry.

Published
2021
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37. On the road to ITER NBIs: SPIDER improvement after first operation and MITICA construction progress

Author

Toigo, V, Marcuzzi, D, Serianni, G, Boldrin, M, Chitarin, G, Bello, S, Grando, L, Luchetta, A, Pasqualotto, R, Zaccaria, P, Zanotto, L, Agnello, R, Agostinetti, P, Agostini, M, Antoni, V, Aprile, D, Barbisan, M, Battistella, M, Berton, G, Bigi, M, Brombin, M, Candeloro, V, Canton, A, Casagrande, R, Cavallini, C, Cavazzana, R, Cordaro, L, Cruz, N, Palma, M, Dan, M, De Lorenzi, A, Delogu, R, De Muri, M, Denizeau, S, Fadone, M, Fellin, F, Ferro, A, Gaio, E, Gasparini, F, Gasparrini, C, Gnesotto, F, Jain, P, Krastev, P, Lopez-Bruna, D, Lorenzini, R, Maistrello, A, Manduchi, G, Manfrin, S, Marconato, N, Martines, E, Martini, G, Martini, S, Milazzo, R, Patton, T, Pavei, M, Peruzzo, S, Pilan, N, Pimazzoni, A, Poggi, C, Pomaro, N, Pouradier-Duteil, B, Recchia, M, Rigoni-Garola, A, Rizzolo, A, Sartori, E, Shepherd, A, Siragusa, M, Sonato, P, Sottocornola, A, Spada, E, Spagnolo, S, Spolaore, M, Taliercio, C, Terranova, D, Tinti, P, Tomsic, P, Trevisan, L, Ugoletti, M, Valente, M, Vignando, M, Zagorski, R, Zamengo, A, Zaniol, B, Zaupa, M, Zuin, M, Cavenago, M, Boilson, D, Rotti, C, Veltri, P, Decamps, H, Dremel, M, Graceffa, J, Geli, F, Urbani, M, Zacks, J, Bonicelli, T, Paolucci, F, Garbuglia, A, Agarici, G, Gomez, G, Gutierrez, D, Kouzmenko, G, Labate, C, Masiello, A, Mico, G, Moreno, J, Pilard, V, Rousseau, A, Simon, M, Kashiwagi, M, Tobari, H, Watanabe, K, Maejima, T, Kojima, A, Oshita, E, Yamashita, Y, Konno, S, Singh, M, Chakraborty, A, Patel, H, Singh, N, Fantz, U, Bonomo, F, Cristofaro, S, Heinemann, B, Kraus, W, Wimmer, C, Wunderlich, D, Fubiani, G, Tsumori, K, Croci, G, Gorini, G, Mccormack, O, Muraro, A, Rebai, M, Tardocchi, M, Giacomelli, L, Rigamonti, D, Taccogna, F, Bruno, D, Rutigliano, M, D'Arienzo, M, Tonti, A, Panin, F, Toigo V., Marcuzzi D., Serianni G., Boldrin M., Chitarin G., Bello S. D., Grando L., Luchetta A., Pasqualotto R., Zaccaria P., Zanotto L., Agnello R., Agostinetti P., Agostini M., Antoni V., Aprile D., Barbisan M., Battistella M., Berton G., Bigi M., Brombin M., Candeloro V., Canton A., Casagrande R., Cavallini C., Cavazzana R., Cordaro L., Cruz N., Palma M. D., Dan M., De Lorenzi A., Delogu R., De Muri M., Denizeau S., Fadone M., Fellin F., Ferro A., Gaio E., Gasparini F., Gasparrini C., Gnesotto F., Jain P., Krastev P., Lopez-Bruna D., Lorenzini R., Maistrello A., Manduchi G., Manfrin S., Marconato N., Martines E., Martini G., Martini S., Milazzo R., Patton T., Pavei M., Peruzzo S., Pilan N., Pimazzoni A., Poggi C., Pomaro N., Pouradier-Duteil B., Recchia M., Rigoni-Garola A., Rizzolo A., Sartori E., Shepherd A., Siragusa M., Sonato P., Sottocornola A., Spada E., Spagnolo S., Spolaore M., Taliercio C., Terranova D., Tinti P., Tomsic P., Trevisan L., Ugoletti M., Valente M., Vignando M., Zagorski R., Zamengo A., Zaniol B., Zaupa M., Zuin M., Cavenago M., Boilson D., Rotti C., Veltri P., Decamps H., Dremel M., Graceffa J., Geli F., Urbani M., Zacks J., Bonicelli T., Paolucci F., Garbuglia A., Agarici G., Gomez G., Gutierrez D., Kouzmenko G., Labate C., Masiello A., Mico G., Moreno J. -F., Pilard V., Rousseau A., Simon M., Kashiwagi M., Tobari H., Watanabe K., Maejima T., Kojima A., Oshita E., Yamashita Y., Konno S., Singh M., Chakraborty A., Patel H., Singh N. P., Fantz U., Bonomo F., Cristofaro S., Heinemann B., Kraus W., Wimmer C., Wunderlich D., Fubiani G., Tsumori K., Croci G., Gorini G., McCormack O., Muraro A., Rebai M., Tardocchi M., Giacomelli L., Rigamonti D., Taccogna F., Bruno D., Rutigliano M., D'Arienzo M., Tonti A., Panin F., Toigo, V, Marcuzzi, D, Serianni, G, Boldrin, M, Chitarin, G, Bello, S, Grando, L, Luchetta, A, Pasqualotto, R, Zaccaria, P, Zanotto, L, Agnello, R, Agostinetti, P, Agostini, M, Antoni, V, Aprile, D, Barbisan, M, Battistella, M, Berton, G, Bigi, M, Brombin, M, Candeloro, V, Canton, A, Casagrande, R, Cavallini, C, Cavazzana, R, Cordaro, L, Cruz, N, Palma, M, Dan, M, De Lorenzi, A, Delogu, R, De Muri, M, Denizeau, S, Fadone, M, Fellin, F, Ferro, A, Gaio, E, Gasparini, F, Gasparrini, C, Gnesotto, F, Jain, P, Krastev, P, Lopez-Bruna, D, Lorenzini, R, Maistrello, A, Manduchi, G, Manfrin, S, Marconato, N, Martines, E, Martini, G, Martini, S, Milazzo, R, Patton, T, Pavei, M, Peruzzo, S, Pilan, N, Pimazzoni, A, Poggi, C, Pomaro, N, Pouradier-Duteil, B, Recchia, M, Rigoni-Garola, A, Rizzolo, A, Sartori, E, Shepherd, A, Siragusa, M, Sonato, P, Sottocornola, A, Spada, E, Spagnolo, S, Spolaore, M, Taliercio, C, Terranova, D, Tinti, P, Tomsic, P, Trevisan, L, Ugoletti, M, Valente, M, Vignando, M, Zagorski, R, Zamengo, A, Zaniol, B, Zaupa, M, Zuin, M, Cavenago, M, Boilson, D, Rotti, C, Veltri, P, Decamps, H, Dremel, M, Graceffa, J, Geli, F, Urbani, M, Zacks, J, Bonicelli, T, Paolucci, F, Garbuglia, A, Agarici, G, Gomez, G, Gutierrez, D, Kouzmenko, G, Labate, C, Masiello, A, Mico, G, Moreno, J, Pilard, V, Rousseau, A, Simon, M, Kashiwagi, M, Tobari, H, Watanabe, K, Maejima, T, Kojima, A, Oshita, E, Yamashita, Y, Konno, S, Singh, M, Chakraborty, A, Patel, H, Singh, N, Fantz, U, Bonomo, F, Cristofaro, S, Heinemann, B, Kraus, W, Wimmer, C, Wunderlich, D, Fubiani, G, Tsumori, K, Croci, G, Gorini, G, Mccormack, O, Muraro, A, Rebai, M, Tardocchi, M, Giacomelli, L, Rigamonti, D, Taccogna, F, Bruno, D, Rutigliano, M, D'Arienzo, M, Tonti, A, Panin, F, Toigo V., Marcuzzi D., Serianni G., Boldrin M., Chitarin G., Bello S. D., Grando L., Luchetta A., Pasqualotto R., Zaccaria P., Zanotto L., Agnello R., Agostinetti P., Agostini M., Antoni V., Aprile D., Barbisan M., Battistella M., Berton G., Bigi M., Brombin M., Candeloro V., Canton A., Casagrande R., Cavallini C., Cavazzana R., Cordaro L., Cruz N., Palma M. D., Dan M., De Lorenzi A., Delogu R., De Muri M., Denizeau S., Fadone M., Fellin F., Ferro A., Gaio E., Gasparini F., Gasparrini C., Gnesotto F., Jain P., Krastev P., Lopez-Bruna D., Lorenzini R., Maistrello A., Manduchi G., Manfrin S., Marconato N., Martines E., Martini G., Martini S., Milazzo R., Patton T., Pavei M., Peruzzo S., Pilan N., Pimazzoni A., Poggi C., Pomaro N., Pouradier-Duteil B., Recchia M., Rigoni-Garola A., Rizzolo A., Sartori E., Shepherd A., Siragusa M., Sonato P., Sottocornola A., Spada E., Spagnolo S., Spolaore M., Taliercio C., Terranova D., Tinti P., Tomsic P., Trevisan L., Ugoletti M., Valente M., Vignando M., Zagorski R., Zamengo A., Zaniol B., Zaupa M., Zuin M., Cavenago M., Boilson D., Rotti C., Veltri P., Decamps H., Dremel M., Graceffa J., Geli F., Urbani M., Zacks J., Bonicelli T., Paolucci F., Garbuglia A., Agarici G., Gomez G., Gutierrez D., Kouzmenko G., Labate C., Masiello A., Mico G., Moreno J. -F., Pilard V., Rousseau A., Simon M., Kashiwagi M., Tobari H., Watanabe K., Maejima T., Kojima A., Oshita E., Yamashita Y., Konno S., Singh M., Chakraborty A., Patel H., Singh N. P., Fantz U., Bonomo F., Cristofaro S., Heinemann B., Kraus W., Wimmer C., Wunderlich D., Fubiani G., Tsumori K., Croci G., Gorini G., McCormack O., Muraro A., Rebai M., Tardocchi M., Giacomelli L., Rigamonti D., Taccogna F., Bruno D., Rutigliano M., D'Arienzo M., Tonti A., and Panin F.

Abstract

To reach fusion conditions and control the plasma configuration in ITER, the next step in tokamak fusion research, two neutral beam injectors (NBIs) will supply 16.5 MW each, by neutralizing accelerated negative hydrogen or deuterium ions. The requirements of ITER NBIs (40A/1 MeV D- ions for ≤1 h, 46A/870 keV H- ions for ≤1000 s) have never been simultaneously attained. So in the Neutral Beam Test Facility (NBTF, Consorzio RFX, Italy) the operation of the full-scale ITER NBI prototype (MITICA) will be tested and optimised up to full performances, focussing on accelerator (including voltage holding), beam optics, neutralisation, residual ion removal. The NBTF includes also the full-scale prototype of the ITER NBI source with 100 keV particle energy (SPIDER), for early investigation of: negative ion production and extraction, source uniformity, negative ion current density and beam optics. This paper will describe the main results of the first two years of SPIDER operation, devoted to characterizing plasma and beam parameters, including investigation of RF-plasma coupling efficiency and magnetic filter field effectiveness in reducing co-extracted electrons. SPIDER is progressing towards the first caesium injection, which aims at increasing the negative ion density. A major shutdown, planned for 2021, to solve the issues identified during the operation and to carry out programmed modifications, will be outlined. The installation of each MITICA power supply and auxiliary system is completed; in-vessel mechanical components are under procurement by Fusion for Energy (F4E). Integration, commissioning and test of the power supplies, procured by F4E and QST, as the Japanese Domestic Agency (JADA), will be presented. In particular, 1.0MV insulating tests were carried out step-by-step and successfully completed. In 2020 integrated tests of the power supplies on the accelerator dummy load started, including the assessment of their resilience to accelerator grid breakdowns usin

Published
2021

39. The impact of PM2.5, PM10 and NO2 on Covid-19 severity in a sample of patients with multiple sclerosis: A case-control study

Author

Ponzano, Marta, primary, Schiavetti, Irene, additional, Bergamaschi, Roberto, additional, Pisoni, Enrico, additional, Bellavia, Andrea, additional, Mallucci, Giulia, additional, Carmisciano, Luca, additional, Inglese, Matilde, additional, Cordioli, Cinzia, additional, Marfia, Girolama Alessandra, additional, Cocco, Eleonora, additional, Immovilli, Paolo, additional, Pesci, Ilaria, additional, Scandellari, Cinzia, additional, Cavalla, Paola, additional, Radaelli, Marta, additional, Vianello, Marika, additional, Vitetta, Francesca, additional, Montepietra, Sara, additional, Amato, Maria Pia, additional, Fioretti, Cristina, additional, Filippi, Massimo, additional, Sartori, Arianna, additional, Caleri, Francesca, additional, Clerico, Marinella, additional, Gallo, Antonio, additional, Conte, Antonella, additional, Clerici, Raffaella, additional, De Luca, Giovanna, additional, Boneschi, Filippo Martinelli, additional, Cantello, Roberto, additional, Calabrese, Massimiliano, additional, Tortorella, Carla, additional, Rovaris, Marco, additional, Verrengia, Elena Pinuccia, additional, Patti, Francesco, additional, Morra, Vincenzo Brescia, additional, Salvetti, Marco, additional, Sormani, Maria Pia, additional, Gianmarco, Abbadessa, additional, Umberto, Aguglia, additional, Lia, Allegorico, additional, Maria, Allegri Rossi Beatrice, additional, Anastasia, Alteno, additional, Pia, Amato Maria, additional, Pietro, Annovazzi, additional, Carlo, Antozzi, additional, Lucia, Appendino, additional, Sebastiano, Arena, additional, Viola, Baione, additional, Roberto, Balgera, additional, Valeria, Barcella, additional, Damiano, Baroncini, additional, Caterina, Barrilà, additional, Mario A, Battaglia, additional, Alessandra, Bellacosa, additional, Gianmarco, Bellucci, additional, Roberto, Bergamaschi, additional, Valeria, Bergamaschi, additional, Daiana, Bezzini, additional, Beatrice, Biolzi, additional, Alvino, Bisecco, additional, Simona, Bonavita, additional, Giovanna, Borriello, additional, Chiara, Bosa, additional, Antonio, Bosco, additional, Francesca, Bovis, additional, Marco, Bozzali, additional, Laura, Brambilla, additional, Vincenzo, Brescia Morra, additional, Giampaolo, Brichetto, additional, Maria, Buccafusca, additional, Elisabetta, Bucciantini, additional, Sebastiano, Bucello, additional, Chiara, Buscarinu Maria, additional, Paola, Cabboi Maria, additional, Massimiliano, Calabrese, additional, Francesca, Calabria, additional, Francesca, Caleri, additional, Federico, Camilli, additional, Maria, Caniatti Luisa, additional, Roberto, Cantello, additional, Marco, Capobianco, additional, Ruggero, Capra, additional, Rocco, Capuano, additional, Luca, Carmisciano, additional, Patrizia, Carta, additional, Paola, Cavalla, additional, Grazia, Celani Maria, additional, Maria, Cellerino, additional, Raffaella, Cerqua, additional, Clara, Chisari, additional, Raffaella, Clerici, additional, Marinella, Clerico, additional, Eleonora, Cocco, additional, Gaia, Cola, additional, Giancarlo, Comi, additional, Paolo, Confalonieri, additional, Antonella, Conte, additional, Zaffira, Conti Marta, additional, Christian, Cordano, additional, Susanna, Cordera, additional, Cinzia, Cordioli, additional, Francesco, Corea, additional, Claudio, Correale, additional, Salvatore, Cottone, additional, Francesco, Crescenzo, additional, Erica, Curti, additional, Alessandro, d'Ambrosio, additional, Emanuele, D'Amico, additional, Chiara, Danni Maura, additional, Alessia, d'Arma, additional, Vincenzo, Dattola, additional, Stefano, de Biase, additional, Giovanna, De Luca, additional, Federica, De Mercanti Stefania, additional, Paolo, De Mitri, additional, Nicola, De Rossi, additional, Nicola, De Stefano, additional, Maria, Della Cava Fabio, additional, Marco, Della Cava, additional, Sonia, Di Lemme, additional, Mario, di Napoli, additional, Alessia, Di Sapio, additional, Renato, Docimo, additional, Anna, Dutto, additional, Luana, Evangelista, additional, Salvatore, Fanara, additional, Roberta, Fantozzi, additional, Diana, Ferraro, additional, Teresa, Ferrò Maria, additional, Massimo, Filippi, additional, Cristina, Fioretti, additional, Mario, Fratta, additional, Jessica, Frau, additional, Marzia, Fronza, additional, Roberto, Furlan, additional, Alberto, Gajofatto, additional, Antonio, Gallo, additional, Paolo, Gallo, additional, Claudio, Gasperini, additional, Anna, Ghazaryan, additional, Bruno, Giometto, additional, Francesca, Gobbin, additional, Flora, Govone, additional, Franco, Granella, additional, Erica, Grange, additional, Grazia, Grasso Maria, additional, Luigi ME, Grimaldi, additional, Angelica, Guareschi, additional, Clara, Guaschino, additional, Simone, Guerrieri, additional, Donata, Guidetti, additional, Barbara, Juergenson Ina, additional, Pietro, Iaffaldano, additional, Antonio, Ianniello, additional, Luigi, Iasevoli, additional, Paolo, Immovilli, additional, Daniele, Imperiale, additional, Teresa, Infante Maria, additional, Matilde, Inglese, additional, Rosa, Iodice, additional, Aniello, Iovino, additional, Giovanna, Konrad, additional, Doriana, Landi, additional, Roberta, Lanzillo, additional, Caterina, Lapucci, additional, Luigi, Lavorgna, additional, Rita, L'Episcopo Maria, additional, Serena, Leva, additional, Giuseppe, Liberatore, additional, Marianna, Lo Re, additional, Marco, Longoni, additional, Leonardo, Lopiano, additional, Lorena, Lorefice, additional, Matteo, Lucchini, additional, Giacomo, Lus, additional, Davide, Maimone, additional, Maria, Malentacchi, additional, Giulia, Mallucci, additional, Simona, Malucchi, additional, Rosa, Mancinelli Chiara, additional, Luca, Mancinelli, additional, Paolo, Manganotti, additional, Teresa, Maniscalco Giorgia, additional, Vittorio, Mantero, additional, Sabrina, Marangoni, additional, Damiano, Marastoni, additional, Alessandra, Marfia Girolama, additional, Fabiana, Marinelli, additional, Alessandro, Marti, additional, Filippo, Martinelli Boneschi, additional, Federco, Masserano Zoli, additional, Francesca, Matta, additional, Laura, Mendozzi, additional, Giuseppe, Meucci, additional, Silvia, Miante, additional, Giuseppina, Miele, additional, Eva, Milano, additional, Massimiliano, Mirabella, additional, Rosanna, Missione, additional, Marcello, Moccia, additional, Lucia, Moiola, additional, Sara, Montepietra, additional, Margherita, MontiBragadin, additional, Federico, Montini, additional, Roberta, Motta, additional, Raffaele, Nardone, additional, Gabri, Nicoletti Carolina, additional, Eduardo, Nobile-Orazio, additional, Agostino, Nozzolillo, additional, Marco, Onofrj, additional, Riccardo, Orlandi, additional, Anna, Palmieri, additional, Damiano, Paolicelli, additional, Livia, Pasquali, additional, Fulvio, Pasquin, additional, Luisa, Pastò, additional, Francesco, Patti, additional, Elisabetta, Pedrazzoli, additional, Paola, Perini, additional, Ilaria, Pesci, additional, Maria, Petracca, additional, Alfredo, Petrone, additional, Carlo, Piantadosi, additional, Anna M, Pietroboni, additional, Federica, Pinardi, additional, Marta, Ponzano, additional, Emilio, Portaccio, additional, Mattia, Pozzato, additional, Carlo, Pozzilli, additional, Luca, Prosperini, additional, Alessandra, Protti, additional, Eugenio, Pucci, additional, Marta, Radaelli, additional, Paolo, Ragonese, additional, Sarah, Rasia, additional, Sabrina, Realmuto, additional, Anna, Repice, additional, Eleonora, Rigoni, additional, Teresa, Rilla Maria, additional, Francesca, Rinaldi, additional, Marcello, Romano Calogero, additional, Marco, Ronzoni, additional, Marco, Rovaris, additional, Francesca, Ruscica, additional, Loredana, Sabattini, additional, Giuseppe, Salemi, additional, Marco, Salvetti, additional, Lorenzo, Saraceno, additional, Alessia, Sartori, additional, Arianna, Sartori, additional, Elvira, Sbragia, additional, Cinzia, Scandellari, additional, Ilaria, Scarano Giuditta, additional, Valentina, Scarano, additional, Irene, Schiavetti, additional, Maria, Sessa, additional, Caterina, Sgarito, additional, Grazia, Sibilia, additional, Gabriele, Siciliano, additional, Alessio, Signori, additional, Elisabetta, Signoriello, additional, Leonardo, Sinisi, additional, Francesca, Sireci, additional, Patrizia, Sola, additional, Claudio, Solaro, additional, Pia, Sormani Maria, additional, Stefano, Sotgiu, additional, Maddalena, Sparaco, additional, Laura, Stromillo Maria, additional, Silvia, Strumia, additional, Laura, Susani Emanuela, additional, Giulietta, Tabiadon, additional, Francesco, Teatini, additional, Gioacchino, Tedeschi, additional, Valentina, Tomassini, additional, Simone, Tonietti, additional, Valentina, Torri Clerici, additional, Carla, Tortorella, additional, Simona, Toscano, additional, Rocco, Totaro, additional, Maria, Trojano, additional, Maria, Trotta, additional, Gabriella, Turano, additional, Monica, Ulivelli, additional, Manzo, Valentino, additional, Giovanna, Vaula, additional, Domizia, Vecchio, additional, Marco, Vercellino, additional, Pinuccia, Verrengia Elena, additional, Marika, Vianello, additional, Eleonora, Virgilio, additional, Francesca, Vitetta, additional, Stefano, Vollaro, additional, Mauro, Zaffaroni, additional, Mauro, Zampolini, additional, Roberto, Zarbo Ignazio, additional, Antonio, Zito, additional, and Luigi, Zuliani, additional

Published
2022
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42. Progress in the design of MITICA control and interlock systems

Author

Adriano Luchetta, A. Rigoni, Lennart Svensson, C. Taliercio, C. Labate, Gabriele Manduchi, F. Paolucci, and N. Pomaro

Subjects
Central interlock system, Computer science, Mechanical Engineering, Interface (computing), Control (management), Control and data acquisition system, 01 natural sciences, 010305 fluids & plasmas, MITICA, Reliability (semiconductor), Nuclear Energy and Engineering, Data sampling, ITER, 0103 physical sciences, Systems engineering, Systems architecture, Neutral beam test facility, General Materials Science, Instrumentation (computer programming), Heating neutral beam injector, Plant system, 010306 general physics, Interlock, Civil and Structural Engineering
Abstract

The construction of MITICA, the full-size prototype of the ITER Heating Neutral Beam Injectors (HNBs) is in progress at the Neutral Beam Test Facility (NBTF) located in Padova, Italy. The design of the central control (CODAS) and interlock (CIS) systems is progressing taking into account the requirements coming from the MITICA plant units, in terms of number and type of interface signals, data sampling frequency values, operating states, protection actions and required reaction times and reliability. As the HNBs will be ITER components, additional requirements derive from the ITER plant control design handbook that specifies the design criteria and standard technologies to be applied to ITER plant systems. A distinction must be made in MITICA between plant units that will be part of the HNB, such as the power supply systems, and plant units that are auxiliaries, such as the gas and vacuum system. In the NBTF these components shall interface with MITICA CODAS and CIS, whereas in ITER they will be autonomous plant systems providing services to the HNB. The distinction reported above suggests defining the architecture of MITICA Instrumentation and Control (I&C) as split into the following functional blocks: i) HNB plant system including components that will be part of the HNB; ii) Service plant system including all operational plant units that need control in the NBTF but are implemented outside the ITER HNB; iii) Diagnostics plant system; iv) Central I&C (CODAS and CIS). The paper presents the requirements for MITICA CODAS and CIS and derives from these the system architecture. The design of CODAS and CIS is discussed with reference to the lesson learned in the implementation of SPIDER CODAS and CIS (the NBTF ion source test bed) and to the technologies suitable for the implementation.

Published
2019
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43. Comparison between patient specific instrumentation and traditional technique in patients with total knee arthroplasty: An observational perspective study

Author

Martina Dalla Libera, Sergio Rigoni, Cesare Chemello, A. Ceccato, D. Pigatto, and Davide Conte

Subjects
musculoskeletal diseases, Knee function, 030222 orthopedics, medicine.medical_specialty, business.industry, Total knee arthroplasty, 030229 sport sciences, Thigh, Article, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, Patient specific instrumentation, Gait analysis, Cohort, Physical therapy, Medicine, Orthopedics and Sports Medicine, In patient, Observational study, business
Abstract

Background Total knee arthroplasty surgery (TKA) using prenavigated Patient Specific Instruments (PSI) technique represents one of the most recent technological evolutions in development of prosthetic surgery. The aim of this study was to evaluate kinematic and functional recovery of patients operated with prenavigated PSI technique compared to those operated with traditional technique. Methods A cohort of 20 patients is divided in two groups; some are operated with traditional technique (with NexGen Knee system) and others with prenavigated PSI technique (with eMP Knee system) at Asiago Hospital. Limb circumferences are measured for edema evaluation and different evaluation forms are provided to patients: SF-36, KSS pre-surgery (T0), KSS 15 (T1) and 45 days after surgery (T2). Gait Analysis is performed 60 days post-surgery, after leaving crutches. Results The analysis of KSS and SF-36 evaluation forms shows a greater improvement in PSI Evolution group in terms of articulation (comparison between T0 and T1), knee function and early return to physical and social activities. Pain is lesser in NexGen group, in an earlier phase, but 45 days after surgery (T2) there are no significant differences between two groups. Perception of general state of health improves more and earlier in NexGen. In NexGen group edema evaluation had significant differences at the level of prosthetic leg, but not in knee and thigh. Overall: the walking pattern is more physiological in PSI Evolution group. Conclusions The present study highlighted the superiority of prenavigated PSI technique over traditional technique in recovering functionality of prosthetic knee and in restoring a more physiological path pattern.

Published
2021
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45. Neoarchean atmospheric chemistry and the preservation of S-MIF in sediments from the São Francisco Craton

Author

Bosco-Santos, Alice, primary, Gilhooly III, William Patrick, additional, Melo-Silva, Paola de, additional, Fouskas, Fotios, additional, Bouyon, Amaury, additional, Motta, João Gabriel, additional, Baldim, Mauricio Rigoni, additional, Fabricio-Silva, Wendell, additional, Philippot, Pascal, additional, and Oliveira, Elson Paiva, additional

Published
2022
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50. Polyionic complexes of chitosan-N-arginine with alginate as pH responsive and mucoadhesive particles for oral drug delivery applications

Author

Ana C.M.F. Patta, Rafael R.M. Madrid, Omar Mertins, Patrick D. Mathews, Emerson Rodrigo da Silva, and Vera L.S. Rigoni

Subjects
Alginates, Nanoparticle, 02 engineering and technology, Biochemistry, Chitosan, 03 medical and health sciences, chemistry.chemical_compound, Biopolymers, Drug Delivery Systems, Intestinal mucosa, Structural Biology, Zeta potential, Animals, Surface charge, Molecular Biology, 030304 developmental biology, Ions, Drug Carriers, 0303 health sciences, Molecular Structure, Chemistry, Spectrum Analysis, Fishes, Biomaterial, General Medicine, Hydrogen-Ion Concentration, 021001 nanoscience & nanotechnology, Monomer, Models, Chemical, Chemical engineering, Nanoparticles, Thermodynamics, 0210 nano-technology, Drug carrier, Algorithms
Abstract

The production of efficient micro and nanoparticles of pH-responsive and mucoadhesive properties is of high scrutiny. We produced a drug carrier bioparticle providing such structural features. Thereby, protonated chitosan bearing chemically bonded arginine was interacted with ionized alginate, leading to the assembling of colloidal particles of specific characteristics. Ideally, the ratio of chitosan-arginine monomers to alginate monomer is 1.6 when the biopolymers are highly charged, providing electrostatic interaction with Gibbs energy compensation around −14 kcal/mol. Both size and surface charge of the bioparticle respond to pH variation, leading to structures of nano to micro hydrodynamic diameters and of positive, nearly neutral and negative zeta potential, with nanoscopic structure changing from mass to surface fractals. The inclusion of two hydrophobic model drugs provided some specific physicochemical features. Following freeze-drying, the bioparticles present both irregular shape and surface morphology, but an overall similar dry structure. An in vivo study of oral administration to teleost fish revealed that the bioparticles attain the intestine mucus and further, the interaction with the intestinal mucosa is timely dependent thanks to the mucoadhesive property. The in vivo study endorsed that the bioparticle provides high compliance to freshwater ornamental fish, highlighting it as a material of promising application.

Published
2020
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