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Start Over Author "Ren, F." Publisher elsevier bv
310 results on '"Ren, F."'

2. 1028P Preliminary phase I results from a first-in-human study of EMB-02, a PD-1xLAG-3 bispecific antibody, in patients (pts) with advanced solid tumors

Author

Day, D., primary, Ganju, V., additional, Chung, K., additional, Si, L., additional, Mao, L., additional, Aghmesheh, M., additional, Hoyer, R., additional, Brewin, K., additional, Zeng, S., additional, Lu, Q., additional, Jiang, C., additional, Ren, F., additional, Wu, X., additional, and Guo, J., additional

Published
2023
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10. Highly sensitive and specific detection of hepatitis B virus DNA and drug resistance mutations utilizing the PCR-based CRISPR-Cas13a system

Author

Wang, S., primary, Li, H., additional, Kou, Z., additional, Ren, F., additional, Jin, Y., additional, Yang, L., additional, Dong, X., additional, Yang, M., additional, Zhao, J., additional, Liu, H., additional, Dong, N., additional, Jia, L., additional, Chen, X., additional, Zhou, Y., additional, Qiu, S., additional, Hao, R., additional, and Song, H., additional

Published
2021
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24. Characterization of Ag+ toxicity on living fibroblast cells by the ferrocenemethanol and oxygen response with the scanning electrochemical microscope

Author

Fu Ren F. Fan, Allen J. Bard, Alexander B. Nepomnyashchii, Mario A. Alpuche-Aviles, Dongping Zhan, and Xiao Li

Subjects
Chemistry, General Chemical Engineering, Cell, Analytical chemistry, chemistry.chemical_element, Electrochemistry, Oxygen, Redox, Analytical Chemistry, Metal, medicine.anatomical_structure, visual_art, Microscopy, medicine, visual_art.visual_art_medium, Biophysics, Viability assay, Fibroblast
Abstract

+ toxicity abstract The viability of living fibroblast cells cultured on a Petri dish was determined by scanning electrochem- ical microscopy (SECM). Three kinds of feedback modes for single living cells were derived with different redox couples: positive, negative and consumptive. The consumptive feedback was unique and distin- guished uptake from the response caused by cell deformation. The toxicity of Ag + ion on the living fibro- blast cells was investigated by using both ferrocenemethanol (FcMeOH) and oxygen (O2 )a s electrochemical mediators. The results showed that Ag + ions could be taken up and then reduced to form sub-micrometer and micrometer sized metal silver particles. The metal silver particles stained fibroblast cells and give a positive feedback with FcMeOH. These were also identified by the results of both SECM and energy dispersive X-ray spectroscopy (EDX). The amount of consumption of dissolved O2 decreased with time, showing the cell status as the cells died. Since O2 is directly involved in cell metabolism and the products of O2 reduction are not re-oxidized by metal silver particles trapped on fibroblast cells, it is a good SECM mediator to characterize drug effects on cell viability. The results suggest the importance of choice of redox mediator in characterizing cell viability.

Published
2013

25. Formation of a silicon layer by electroreduction of SiO2 nanoparticles in CaCl2 molten salt

Author

Sung Ki Cho, Fu Ren F. Fan, and Allen J. Bard

Subjects
inorganic chemicals, Auxiliary electrode, Materials science, Silicon, General Chemical Engineering, Inorganic chemistry, technology, industry, and agriculture, chemistry.chemical_element, Glassy carbon, equipment and supplies, complex mixtures, Reference electrode, Electrochemical cell, stomatognathic diseases, chemistry, Electrochemistry, Crystalline silicon, Molten salt, Silicon oxide
Abstract

We observe the electrochemical formation of a silicon layer on a molybdenum (Mo) electrode at 850 °C in a CaCl2 melt containing silicon oxide (SiO2) nanoparticles (NPs). A stable electrochemical cell for high temperature molten salt was fabricated from a sealed quartz tube, with a glassy carbon counter electrode and a Ca/Ca2+ dynamic reference electrode. When SiO2 NPs are added into the CaCl2 melt, the reduction current and the generation of a new redox couple relating to the reduced silicon were observed in a cyclic voltammogram at Mo. Spectroscopic analyses confirmed the formation of a silicon layer from the reduction of SiO2 NPs. Although the deposit was not continuous, XPS shows that it is silicon of good purity and XRD shows the pattern of crystalline silicon. We also investigated the dissolved silicon species generated after the oxidation of electrodeposited silicon in CaCl2 melt, which produces a redox couple at potentials positive of the deposition potential. We tentatively attribute it to the oxidation and re-reduction of an insoluble Si–Cl surface species.

Published
2012

40. Electrochemistry and electrogenerated chemiluminescence of films of the conjugated polymer 4-methoxy-(2-ethylhexoxyl)-2,5-polyphenylenevinylene

Author

Floyd Klavetter, Alan J. Heeger, Mark M. Richter, Fu Ren F. Fan, and Allen J. Bard

Subjects
General Physics and Astronomy, chemistry.chemical_element, Propylamine, Electrochemistry, Photochemistry, law.invention, chemistry.chemical_compound, chemistry, law, Oxidizing agent, Electrochemiluminescence, Physical and Theoretical Chemistry, Platinum, Luminescence, Acetonitrile, Chemiluminescence
Abstract

The thin film electrochemistry and electrogenerated chemiluminescence (ECL) of the title compound were obtained on Pt electrodes (CH 3 CN/0.1 M tetrabutylammonium fluoroborate). Orange luminescence (λ max =622 nm) was obtained by pulsing the potentials between +0.40 and −2.35 V versus Fc/Fc + as well as by oxidizing the system in the presence of TPAH (TPAH=tri- n -propylamine), which generates the strongly reducing intermediate TPA , and by reducing the system in the presence of S 2 O 8 2- , which produces the strongly oxidizing intermediate SO 4 −

Published
1994

46. Scanning electrochemical microscopy part 13. Evaluation of the tip shapes of nanometer size microelectrodes

Author

Michael V. Mirkin, Fu Ren F. Fan, and Allen J. Bard

Subjects
Resistive touchscreen, Chemistry, Scanning electron microscope, business.industry, General Chemical Engineering, Capacitive sensing, Radius, Spherical segment, Analytical Chemistry, Microelectrode, Scanning electrochemical microscopy, Optics, Electrode, Electrochemistry, business
Abstract

The shape of steady-state current-distance (iT-d) curves obtained by scanning electrochemical microscopy (SECM) with a submicrometer conical-type tip is substantially different from that obtained with a microdisk tip. A model is proposed to describe the iT-d curves for tips shaped as cones or spherical segments. In each case a family of theoretical working curves, computed for different values of a single adjustable parameter (the height of a cone or a segment), was used to fit the experimental curves obtained with tips approaching a conductive or insulating substrate. A good fit of the experimental and theoretical curves can be obtained only for a very narrow range of the tip shape parameters, giving confidence in the reliability of the proposed method. The shape parameters for two substantially different microelectrodes are evaluated. A 420 nm radius tip was shown to be a fairly sharp cone with a height-to-radius ratio k of 0.8. An 80 nm radius tip can be represented as either a cone or spherical segment, because of the small k = 0.2. The radius values obtained from iT-d curves agree with those estimated from steady-state current values. The cyclic voltammograms (CVs) obtained at these microtip electrodes have a regular shape with very small capacitive and resistive background. New analytical approximations for iT-d curves are also proposed for SECM with a disk-shaped tip over conductive and insulating substrates.

Published
1992

49. Size quantization of FeS2 (pyrite) produced in a polymer matrix

Author

Jyh Myng Zen, Allen J. Bard, Fu Ren F. Fan, and Guancheng Chen

Subjects
chemistry.chemical_classification, Absorption spectroscopy, Ion exchange, Inorganic chemistry, Analytical chemistry, General Physics and Astronomy, Polymer, Matrix (chemical analysis), chemistry.chemical_compound, Quantization (physics), chemistry, Absorption edge, Nafion, Physical and Theoretical Chemistry, Ion-exchange resin
Abstract

Quantum or Q-particles of FeS2 were synthesized in an ion-exchange polymer (Nafion) matrix by treatment of Fe2+-exchanged polymer with H2S and S at 120°C for 16 days. For comparison Q-FeS2 was also prepared in MeOH and MeCN. Size quantization effects were determined from the absorption spectra. Compared to bulk FeS2(Eg=1.0±0.2 eV), a blue-shift of about 0.5 eV was observed for the absorption edge of the Q-particles prepared in Nafion, while a shift of about 1.0 eV was observed for the Q-colloidal particles suspended in the organic solvents. The smaller blue-shift for the sample prepared in Nafion may be related to the effect of moisture on particle growth.

Published
1990

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