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1. Procedural Time and Outcomes of Chronic Total Occlusion Percutaneous Coronary Intervention

Author

Athanasios Rempakos, Spyridon Kostantinis, Bahadir Simsek, Judit Karacsonyi, James W. Choi, Paul Poommipanit, Jaikirshan J Khatri, Wissam Jaber, Stephane Rinfret, William Nicholson, Sevket Gorgulu, Farouc A. Jaffer, Raj Chandwaney, Luiz F. Ybarra, Rodrigo Bagur, Khaldoon Alaswad, Oleg Krestyaninov, Dmitrii Khelimskii, Dimitrios Karmpaliotis, Barry F. Uretsky, Korhan Soylu, Ufuk Yildirim, Srinivasa Potluri, Karim M. Al-Azizi, Bavana V. Rangan, Olga C. Mastrodemos, Salman Allana, Yader Sandoval, M. Nicholas Burke, Emmanouil S. Brilakis, and Tıp Fakültesi

Subjects
Cardiology and Cardiovascular Medicine
Abstract

Abstracat : Chronic total occlusion (CTO) percutaneous coronary interventions (PCIs) can be lengthy procedures. We sought to investigate the effect of procedural time on CTO PCI outcomes. We examined the procedural time required for the various steps of CTO PCI in 6,442 CTO PCIs at 40 US and non-US centers between 2012 and 2022. The mean and median procedure times were 129 § 76 and 112 minutes, respectively, with no significant change over time. The median times from access to wire insertion, guidewire manipulation time, and post crossing were 20, 32, and 53 minutes, respectively. Lesions crossed in

Published
2023
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2. Outcomes of Chronic Total Occlusion Percutaneous Coronary Intervention After a Previous Failed Attempt

Author

Athanasios Rempakos, Spyridon Kostantinis, Bahadir Simsek, Judit Karacsonyi, James W. Choi, Paul Poommipanit, Jaikirshan J. Khatri, Wissam Jaber, Stephane Rinfret, William Nicholson, Sevket Gorgulu, Farouc A. Jaffer, Raj Chandwaney, Luiz F. Ybarra, Rodrigo Bagur, Khaldoon Alaswad, Oleg Krestyaninov, Dmitrii Khelimskii, Dimitrios Karmpaliotis, Barry F. Uretsky, Korhan Soylu, Ufuk Yildirim, Srinivasa Potluri, Bavana V. Rangan, Olga C. Mastrodemos, Salman Allana, Yader Sandoval, Nicholas M. Burke, Emmanouil S. Brilakis, and Tıp Fakültesi

Subjects
Cardiology and Cardiovascular Medicine
Abstract

The impact of a previous failure on procedural techniques and outcomes of chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has received limited study. We examined the clinical and angiographic characteristics and procedural outcomes of 9,393 patients who underwent 9,560 CTO PCIs at 42 United States and non-United States centers between 2012 and 2022. A total of 1,904 CTO lesions (20%) had a previous failed PCI attempt. Patients who underwent reattempt CTO PCI were more likely to have a family history of coronary artery disease (37% vs 31%, p 30 CTO PCIs annually were more likely to achieve technical success in patients with previous failure. In conclusion, a previous failed CTO PCI attempt was associated with higher lesion complexity, longer procedure time, and lower technical success; however, the association with lower technical success did not remain significant in multivariable analysis.

Published
2023
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3. Use of Mechanical Circulatory Support in Chronic Total Occlusion Percutaneous Coronary Intervention

Author

Judit, Karacsonyi, Karen, Deffenbacher, Keith H, Benzuly, James D, Flaherty, Khaldoon, Alaswad, Mir, Basir, Michael S, Megaly, Farouc, Jaffer, Darshan, Doshi, Paul, Poommipanit, Jaikirshan, Khatri, Mitul, Patel, Robert, Riley, Abdul, Sheikh, Jason R, Wollmuth, Ethan, Korngold, Barry F, Uretsky, Robert W, Yeh, Raj H, Chandwaney, Ahmed M, Elguindy, Khalid, Tammam, Nidal, AbiRafeh, Christian W, Schmidt, Brynn, Okeson, Spyridon, Kostantinis, Bahadir, Simsek, Bavana V, Rangan, Emmanouil S, Brilakis, and Daniel R, Schimmel

Subjects
Cardiology and Cardiovascular Medicine
Abstract

The use of mechanical circulatory support (MCS) in chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has received limited study. We analyzed the clinical and angiographic characteristics, and procedural outcomes of 7,171 CTO PCIs performed between 2012 and 2021 at 35 international centers. Mean age was 64.5 ± 10 years, mean left ventricular ejection fraction was 50 ± 13%. MCS was used in 4.5%, prophylactically in 78.7%, and urgently in 21.3%. The most common type of MCS overall was Impella CP (Abiomed) (55.5%), followed by intra-aortic balloon pump (14.8%) and TandemHeart (LivaNova Inc.) (10.0%). Prophylactic MCS patients were more likely to have diabetes mellitus (55% vs 42%, p0.001) and had more complex lesions compared with cases without prophylactic MCS (Japan-CTO score: 2.80 ± 1.22 vs 2.39 ± 1.27, p0.001). Cases with prophylactic MCS had similar technical (86% vs 87%, p = 0.643) but lower procedural (80% vs 86%, p = 0.028) success rates and higher rates of periprocedural major cardiac adverse events compared with no prophylactic MCS use (6.55% vs 1.68%, p0.001). Urgent MCS use was associated with lower technical (68% vs 87%, p0.001) and procedural (39% vs 86%, p0.001) success rates and higher major cardiac adverse events compared with no-MCS use (32.26% vs 1.68%, p0.001). The differences persisted in multivariable analyses. In summary, in this contemporary multicenter registry, MCS was used in 4.5% of CTO PCIs, mostly prophylactically (78.7%). Elective MCS cases had similar technical success but a higher risk of complications. Urgent MCS cases had lower technical and procedural success and higher periprocedural major complication rates.

Published
2023
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4. Preprocedural coronary computed tomography angiography in chronic total occlusion percutaneous coronary intervention: Insights from the PROGRESS-CTO registry

Author

Bahadir Simsek, Farouc A. Jaffer, Spyridon Kostantinis, Judit Karacsonyi, Hideki Koike, Darshan Doshi, Khaldoon Alaswad, Sevket Gorgulu, Omer Goktekin, Jaikirshan Khatri, Paul Poommipanit, Oleg Krestyaninov, Rhian Davies, Ahmed ElGuindy, Brian K. Jefferson, Taral Patel, Mitul Patel, Stephane Rinfret, Wissam A. Jaber, William Nicholson, Nidal Abi Rafeh, Ufuk Yildirim, Korhan Soylu, Salman Allana, Bavana V. Rangan, Olga C. Mastrodemos, Yader Sandoval, M. Nicholas Burke, and Emmanouil S. Brilakis

Subjects
Percutaneous Coronary Intervention, Treatment Outcome, Coronary Occlusion, Computed Tomography Angiography, Risk Factors, Chronic Disease, Humans, Calcium, Registries, Coronary Angiography, Cardiology and Cardiovascular Medicine
Abstract

Preprocedural coronary computed tomography angiography (CCTA) can be useful in procedural planning for chronic total occlusion (CTO) percutaneous coronary intervention (PCI).We examined the clinical, angiographic and procedural characteristics and outcomes of cases with vs. without preprocedural CCTA in PROGRESS-CTO (NCT02061436). Multivariable logistic regression was used to adjust for confounding factors.Of 7034 CTO PCI cases, preprocedural CCTA was used in 375 (5.3%) with increasing frequency over time. Patients with preprocedural CCTA had a higher prevalence of prior coronary artery bypass graft surgery (39% vs. 27%, p 0.001) and angiographically unfavorable characteristics including higher prevalence of proximal cap ambiguity (52% vs. 33%, p 0.001) and moderate/severe calcification (59% vs. 41%, p 0.001) compared with those without CCTA. CCTA helped resolve proximal cap ambiguity in 27%, identified significant calcium not seen on diagnostic angiography in 18%, changed estimated CTO length by5 mm in 10%, and was performed as part of initial coronary artery disease work up in 19%. CCTA cases had higher J-CTO (2.6 ± 1.2 vs. 2.3 ± 1.3, p 0.001) and PROGRESS-CTO (1.3 ± 1.0 vs. 1.2 ± 1.0 p = 0.027) scores. After adjusting for potential confounders, cases with preprocedural CCTA had similar technical success (odds ratio [OR]: 1.18, 95% confidence interval [CI], 0.83-1.67) and incidence of major adverse cardiovascular events (OR: 1.47, 95% CI, 0.72-3.00).Preprocedural CCTA was used in ~5% of CTO PCI cases. While CCTA may help with procedural planning, especially in complex cases, technical success and MACE were similar with or without CCTA.

Published
2022
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5. Percutaneous coronary intervention of chronic total occlusions involving a bifurcation: Insights from the PROGRESS-CTO registry

Author

Ilias Nikolakopoulos, Evangelia Vemmou, Judit Karacsonyi, Khaldoon Alaswad, Dimitri Karmpaliotis, Nidal Abi Rafeh, Daniel Schimmel, Keith Benzuly, James D. Flaherty, Paul Poommipanit, Ahmed M. ElGuindy, M. Nicholas Burke, and Emmanouil S. Brilakis

Subjects
Percutaneous Coronary Intervention, Treatment Outcome, Coronary Occlusion, Risk Factors, Chronic Disease, Humans, Registries, Coronary Angiography, Cardiology and Cardiovascular Medicine
Abstract

The impact of bifurcations at the proximal or distal cap on the outcomes of chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has received limited study.We analyzed the clinical, angiographic, and procedural data of 4,584 cases performed in patients between 2012 and 2020 in a global CTO PCI registry. We compared 4 groups according to the bifurcation location: "proximal cap," "distal cap," "proximal and distal cap," and "no bifurcation."The CTO involved a bifurcation in 67% cases, as follows: proximal cap (n = 1451, 33%), distal cap (n = 622, 14%), or both caps (n = 954, 21%). "Proximal and distal cap" cases had higher J-CTO compared with "proximal cap," "distal cap," and "no bifurcation" cases (2.9 ± 1.1 vs 2.5 ± 1.1 vs 2.4 ± 1.2 vs 2.0 ± 1.2, P 0.0001), and they were also associated with a lower technical success rate (79% vs 85% vs 85% vs 90%, P 0.0001), higher pericardiocentesis rate (1% vs 1% vs 0.2% vs 0.3%, P = 0.02), and higher emergency coronary artery bypass graft surgery rate (0.3% vs 0% vs 0% vs 0%, P = 0.01).More than two-thirds of CTO PCIs involve a bifurcation, which is associated with lower technical success and higher risk of complications.

Published
2022
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6. Laser for balloon uncrossable and undilatable chronic total occlusion interventions

Author

Nidal Abi Rafeh, Khaldoon Alaswad, Mohaned Egred, Emmanouil S. Brilakis, James W. Choi, Evangelia Vemmou, Imre Ungi, Ahmed ElGuindy, Judit Karacsonyi, Ilias Nikolakopoulos, and Paul Poommipanit

Subjects
Male, medicine.medical_specialty, Percutaneous, medicine.medical_treatment, Psychological intervention, 030204 cardiovascular system & hematology, Coronary Angiography, Balloon, Total occlusion, 03 medical and health sciences, Percutaneous Coronary Intervention, 0302 clinical medicine, Risk Factors, Patient age, medicine, Humans, Registries, 030212 general & internal medicine, Major complication, Aged, business.industry, Lasers, Percutaneous coronary intervention, Middle Aged, Surgery, Treatment Outcome, Coronary Occlusion, Chronic Disease, Conventional PCI, Cardiology and Cardiovascular Medicine, business
Abstract

There is limited information on use of laser in complex percutaneous coronary interventions (PCI). We examined the impact of laser on the outcomes of balloon uncrossable and balloon undilatable chronic total occlusion (CTO) PCI.We reviewed baseline clinical and angiographic characteristics and procedural outcomes of 4845 CTO PCIs performed between 2012 and 2020 at 32 centers.Of the 4845 CTO lesions, 752 (15.5%) were balloon uncrossable (523 cases) or balloon undilatable (356 cases) and were included in this analysis. Mean patient age was 66.9 ± 10 years and 83% were men. Laser was used in 20.3% of the lesions. Compared with cases in which laser was not used, laser was more commonly used in longer length occlusions (33 [21, 50] vs. 25 [15, 40] mm, p = 0.0004) and in-stent restenotic lesions (41% vs. 20%, p0.0001). Laser use was associated with higher technical (91.5% vs. 83.1%, p = 0.010) and procedural (88.9% vs. 81.6%, p = 0.033) success rates and similar incidence of major adverse cardiac events (3.92% vs. 3.51%, p = 0.805). Laser use was associated with longer procedural (169 [109, 231] vs. 130 [87, 199], p0.0001) and fluoroscopy time (64 [40, 94] vs. 50 [31, 81], p = 0.003).In a contemporary, multicenter registry balloon uncrossable and balloon undilatable lesions represented 15.5% of all CTO PCIs. Laser was used in approximately one-fifth of these cases and was associated with high technical and procedural success and similar major complication rates.

Published
2021
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7. B-11 | Donor Vessel Injury During Percutaneous Coronary Interventions for Chronic Total Occlusion: Insights from the PROGRESS-CTO registry

Author

Spyridon Kostantinis, Athanasios Rempakos, Bahadir Simsek, Judit Karacsonyi, Salman S. Allana, Khaldoon Alaswad, Mir B. Basir, Oleg Krestyaninov, Dmitrii Khelimskii, Şevket Görgülü, Rhian E. Davies, Stewart M. Benton, Jaikirshan Khatri, Paul Poommipanit, James W. Choi, Wissam A. Jaber, Stéphane Rinfret, William J. Nicholson, Nazif Aygul, Bulent Behlul Altunkeser, Michail Koutouzis, Ioannis Tsiafoutis, Ahmed Elguindy, Nidal Abi Rafeh, Ömer Göktekin, Olga C. Mastrodemos, Bavana V. Rangan, Yader B. Sandoval, M. Nicholas Burke, and Emmanouil S. Brilakis

Published
2023
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8. B-20 | Assessment of the ERCTO Score for Predicting Success in Retrograde Chronic Total Occlusion Percutaneous Coronary Interventions in the PROGRESS-CTO Registry

Author

Athanasios Rempakos, Bahadir Simsek, Spyridon Kostantinis, Judit Karacsonyi, James W. Choi, Paul Poommipanit, Jaikirshan Khatri, Wissam A. Jaber, Stéphane Rinfret, William J. Nicholson, Şevket Görgülü, Farouc A. Jaffer, Brian Jefferson, Khaldoon Alaswad, Oleg Krestyaninov, Dmitrii Khelimskii, Dimitrios Karmpaliotis, Rhian E. Davies, Stewart M. Benton, Nazif Aygul, Srini Potluri, Karim Al-Azizi, Bavana V. Rangan, Olga Mastrodemos, Salman S. Allana, Yader B. Sandoval, M. Nicholas Burke, and Emmanouil S. Brilakis

Published
2023
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9. B-12 | Approaches to and Outcomes of Chronic Total Occlusion Percutaneous Coronary Intervention of the Left Anterior Descending Artery: Insights from the PROGRESS-CTO Registry

Author

Spyridon Kostantinis, Athanasios Rempakos, Bahadir Simsek, Judit Karacsonyi, Salman S. Allana, Khaldoon Alaswad, Mir B. Basir, Oleg Krestyaninov, Dmitrii Khelimskii, Şevket Görgülü, Rhian E. Davies, Farouc A. Jaffer, Jaikirshan Khatri, Paul Poommipanit, James W. Choi, Wissam A. Jaber, Stéphane Rinfret, William J. Nicholson, Brian Jefferson, Taral N. Patel, Karim Al-Azizi, Srini Potluri, Basem Elbarouni, Nazif Aygul, Bulent Behlul Altunkeser, Ahmed Elguindy, Nidal Abi Rafeh, Ömer Göktekin, Olga Mastrodemos, Bavana V. Rangan, Yader B. Sandoval, M. Nicholas Burke, and Emmanouil S. Brilakis

Published
2023
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10. B-19 | Follow-Up Outcomes of Chronic Total Occlusion Percutaneous Coronary Intervention: Insights from the PROGRESS-CTO Registry

Author

Athanasios Rempakos, Spyridon Kostantinis, Bahadir Simsek, Judit Karacsonyi, James W. Choi, Paul Poommipanit, Jaikirshan Khatri, Wissam A. Jaber, Stéphane Rinfret, William J. Nicholson, Şevket Görgülü, Farouc A. Jaffer, Brian Jefferson, Khaldoon Alaswad, Oleg Krestyaninov, Dmitrii Khelimskii, Dimitrios Karmpaliotis, Rhian E. Davies, Stewart M. Benton, Nazif Aygul, Jarrod Frizzell, M. Niranjan Reddy, Bavana V. Rangan, Olga Mastrodemos, Salman S. Allana, Yader B. Sandoval, M. Nicholas Burke, and Emmanouil S. Brilakis

Published
2023
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11. B-18 | Procedural Time and Outcomes of Chronic Total Occlusion Percutaneous Coronary Intervention: Insights from the PROGRESS-CTO Registry

Author

Athanasios Rempakos, Spyridon Kostantinis, Bahadir Simsek, Judit Karacsonyi, James W. Choi, Paul Poommipanit, Jaikirshan Khatri, Wissam A. Jaber, Stéphane Rinfret, William J. Nicholson, Şevket Görgülü, Farouc A. Jaffer, Raj H. Chandwaney, Luiz Fernando Ybarra, Rodrigo Bagur, Khaldoon Alaswad, Oleg Krestyaninov, Dmitrii Khelimskii, Dimitrios Karmpaliotis, Barry F. Uretsky, Korhan Soylu, Ufuk Yildirim, Srini Potluri, Karim Al-Azizi, Bavana V. Rangan, Olga Mastrodemos, Salman S. Allana, Yader B. Sandoval, M. Nicholas Burke, and Emmanouil S. Brilakis

Published
2023
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12. B-24 | Periprocedural Mortality in Chronic Total Occlusion Percutaneous Coronary Intervention: Insights from the PROGRESS-CTO Registry

Author

Bahadir Simsek, Athanasios Rempakos, Spyridon Kostantinis, Judit Karacsonyi, Şevket Görgülü, Khaldoon Alaswad, James W. Choi, Farouc A. Jaffer, Darshan Doshi, Paul Poommipanit, Nazif Aygul, Oleg Krestyaninov, Dmitrii Khelimskii, Barry F. Uretsky, Rhian E. Davies, Ömer Göktekin, Ahmed Elguindy, Brian Jefferson, Taral N. Patel, Mitul P. Patel, Abdul M. Sheikh, Dimitrios Karmpaliotis, Srini Potluri, Karim Al-Azizi, Olga C. Mastrodemos, Bavana V. Rangan, Salman S. Allana, Yader B. Sandoval, M. Nicholas Burke, and Emmanouil S. Brilakis

Published
2023
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13. B-13 | Impact of Proximal Vessel Tortuosity on Procedural Techniques and Outcomes of Chronic Total Occlusion Percutaneous Coronary Intervention: Insights from the PROGRESS-CTO Registry

Author

Spyridon Kostantinis, Athanasios Rempakos, Bahadir Simsek, Judit Karacsonyi, Salman S. Allana, Khaldoon Alaswad, Mir B. Basir, Oleg Krestyaninov, Dmitrii Khelimskii, Şevket Görgülü, Rhian E. Davies, Stewart M. Benton, Jaikirshan Khatri, Paul Poommipanit, James W. Choi, Wissam A. Jaber, Stéphane Rinfret, William J. Nicholson, Farouc A. Jaffer, Dr. Jimmy Lee Kerrigan, Elias Victor Haddad, Mitul P. Patel, Ehtisham Mahmud, Korhan Soylu, Ufuk Yildirim, Ahmed Elguindy, Nidal Abi Rafeh, Ömer Göktekin, Olga Mastrodemos, Bavana V. Rangan, Yader B. Sandoval, M. Nicholas Burke, and Emmanouil S. Brilakis

Published
2023
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14. URGENT MECHANICAL CIRCULATORY SUPPORT SCORE IN CHRONIC TOTAL OCCLUSION PERCUTANEOUS CORONARY INTERVENTION

Author

Judit Karacsonyi, Larissa Stanberry, Bahadir Simsek, Spyridon Kostantinis, Salman S. Allana, Khaldoon Alaswad, Farouc A. Jaffer, Paul Poommipanit, Jaikirshan J. Khatri, Mitul P. Patel, Abdul Sheikh, Jason R. Wollmuth, Barry F. Uretsky, Robert W. Yeh, Raj H. Chandwaney, Athanasios Rempakos, Ahmed Mohamed ElGuindy, Nidal Abi Rafeh, Yader Sandoval, M Nicholas Burke, Olga Mastrodemos, Brynn Okeson, Bavana V. Rangan, Imre Ungi, and Emmanouil S. Brilakis

Subjects
Cardiology and Cardiovascular Medicine
Published
2023
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15. CONTEMPORARY OUTCOMES OF CHRONIC TOTAL OCCLUSION INTERVENTIONS: UPDATE FROM THE PROGRESS-CTO (PROSPECTIVE GLOBAL REGISTRY FOR THE STUDY OF CHRONIC TOTAL OCCLUSION INTERVENTION) INTERNATIONAL REGISTRY

Author

Salman S. Allana, Spyridon Kostantinis, Bahadir Simsek, Judit Karacsonyi, Khaldoon Alaswad, Athanasios Rempakos, Dmitrii Khelimskii, Dimitrios I. Karmpaliotis, Farouc A. Jaffer, Jaikirshan J. Khatri, Paul Poommipanit, James W. Choi, Mitul P. Patel, Michail Koutouzis, Ehtisham Mahmud, Basem Elbarouni, Wissam A. Jaber, Stéphane Rinfret, Srinivasa P. Potluri, William J. Nicholson, Brian K. Jefferson, Sevket Gorgulu, Raj H. Chandwaney, Bavana V. Rangan, and Emmanouil S. Brilakis

Subjects
Cardiology and Cardiovascular Medicine
Published
2023
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16. IMPACT OF QUALITY OF DISTAL TARGET VESSEL ON THE OUTCOMES OF CHRONIC TOTAL OCCLUSION INTERVENTION: INSIGHTS FROM THE PROGRESS-CTO REGISTRY

Author

Salman S. Allana, Spyridon Kostantinis, Judit Karacsonyi, Bahadir Simsek, Paul Poommipanit, Jaikirshan J. Khatri, James W. Choi, Khaldoon Alaswad, Stéphane Rinfret, Wissam A. Jaber, William J. Nicholson, Oleg Krestianinov, Dmitrii Khelimskii, Dimitrios I. Karmpaliotis, Farouc A. Jaffer, Mitul P. Patel, Ehtisham Mahmud, Michail Koutouzis, Basem Elbarouni, Yader Sandoval, Ufuk Yildirim, Barry F. Uretsky, Korhan Soylu, Bavana V. Rangan, and Emmanouil S. Brilakis

Subjects
Cardiology and Cardiovascular Medicine
Published
2023
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17. LESION COMPLEXITY AND PROCEDURAL OUTCOMES ASSOCIATED WITH OSTIAL CHRONIC TOTAL OCCLUSIONS: INSIGHTS FROM THE PROGRESS-CTO REGISTRY

Author

Salman S. Allana, Spyridon Kostantinis, Bahadir Simsek, Judit Karacsonyi, Khaldoon Alaswad, Paul Poommipanit, Jaikirshan J. Khatri, James W. Choi, Athanasios Rempakos, Oleg Krestianinov, Dmitrii Khelimskii, Dimitrios I. Karmpaliotis, Farouc A. Jaffer, Rhian E. Davies, Rodrigo Bagur, Sevket Gorgulu, Srinivasa P. Potluri, Yader Sandoval, Ehtisham Mahmud, Mitul P. Patel, Brian K. Jefferson, Raj H. Chandwaney, M Nicholas Burke, Bavana V. Rangan, and Emmanouil S. Brilakis

Subjects
Cardiology and Cardiovascular Medicine
Published
2023
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18. OUTCOMES OF PATIENTS WITH ACUTE CORONARY SYNDROMES UNDERGOING CHRONIC TOTAL OCCLUSION PERCUTANEOUS CORONARY INTERVENTION

Author

Bahadir Simsek, Spyridon Kostantinis, Judit Karacsonyi, Khaldoon Alaswad, Farouc A. Jaffer, Darshan Doshi, Jaikirshan J. Khatri, Paul Poommipanit, Sevket Gorgulu, Nazif Aygul, Nidal Abi Rafeh, Oleg Krestianinov, James W. Choi, Barry F. Uretsky, Rhian E. Davies, Omer Goktekin, Ahmed Mohamed ElGuindy, Brian K. Jefferson, Mitul P. Patel, Bavana V. Rangan, Athanasios Rempakos, Salman S. Allana, Yader Sandoval, M. Nicholas Burke, and Emmanouil S. Brilakis

Subjects
Cardiology and Cardiovascular Medicine
Published
2023
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19. EFFECT OF OCCLUSION LESION AGE ON OUTCOMES OF CHRONIC TOTAL OCCLUSION PERCUTANEOUS CORONARY INTERVENTION

Author

Judit Karacsonyi, Spyridon Kostantinis, Bahadir Simsek, Salman S. Allana, Athanasios Rempakos, Jaikirshan J. Khatri, Oleg Krestianinov, Farouc A. Jaffer, Khaldoon Alaswad, Ahmed Mohamed ElGuindy, Brian K. Jefferson, Sevket Gorgulu, Paul Poommipanit, Dimitri Karmpaliotis, Ajay J. Kirtane, Margaret McEntegart, James W. Choi, Nidal Abi Rafeh, Omer Goktekin, Yader Sandoval, M Nicholas Burke, Olga Mastrodemos, Bavana V. Rangan, Imre Ungi, and Emmanouil S. Brilakis

Subjects
Cardiology and Cardiovascular Medicine
Published
2023
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20. EQUIPMENT UTILIZATION IN CHRONIC TOTAL OCCLUSION PERCUTANEOUS CORONARY INTERVENTIONS: INSIGHTS FROM THE PROGRESS-CTO REGISTRY

Author

Spyridon Kostantinis, Bahadir Simsek, Judit Karacsonyi, Khaldoon Alaswad, Farouc A. Jaffer, Jaikirshan J. Khatri, Paul Poommipanit, Rhian E. Davies, Stéphane Rinfret, Wissam A. Jaber, James W. Choi, Mitul P. Patel, Brian K. Jefferson, Jimmy L. Kerrigan, Basem Elbarouni, Nidal Abi Rafeh, Omer Goktekin, Ahmed Mohamed ElGuindy, Salman S. Allana, Olga Mastrodemos, Athanasios Rempakos, Bavana V. Rangan, Yader Sandoval, M Nicholas Burke, and Emmanouil S. Brilakis

Subjects
Cardiology and Cardiovascular Medicine
Published
2023
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21. TCT-123 Predictors of Success in Primary Retrograde Strategy in Chronic Total Occlusion Percutaneous Coronary Intervention: Insights From the PROGRESS-CTO Registry

Author

Bahadir Simsek, Spyridon Kostantinis, Judit Karacsonyi, Khaldoon Alaswad, Dimitri Karmpaliotis, Farouc Jaffer, Jaikirshan Khatri, Paul Poommipanit, Sevket Gorgulu, Omer Goktekin, Oleg Krestyaninov, Rhian Davies, Ahmed ElGuindy, Elias Haddad, Jimmy Kerrigan, Mitul Patel, Raj Chandwaney, Olga Mastrodemos, Salman Allana, Bavana Rangan, and Emmanouil Brilakis

Subjects
Cardiology and Cardiovascular Medicine
Published
2022
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22. TCT-109 Use of Subintimal Tracking and Reentry Technique in Chronic Total Occlusion Percutaneous Coronary Intervention

Author

Judit Karacsonyi, Spyridon Kostantinis, Bahadir Simsek, Khaldoon Alaswad, Dimitri Karmpaliotis, Ajay Kirtane, Margaret McEntegart, Farouc Jaffer, James Choi, Paul Poommipanit, Michalis Koutouzis, Ioannis Tsiafoutis, Jaikirshan Khatri, David Kandzari, Raj Chandwaney, Basem Elbarouni, Sevket Gorgulu, Ahmed ElGuindy, Nidal Abi-Rafeh, Omer Goktekin, Imre Ungi, Bavana Rangan, Olga Mastrodemos, Yader Sandoval, Salman Allana, M. Nicholas Burke, and Emmanouil Brilakis

Subjects
Cardiology and Cardiovascular Medicine
Published
2022
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23. TCT-117 Impact of Proximal Cap Ambiguity on the Outcomes of Chronic Total Occlusion Intervention: Insights From the PROGRESS-CTO Registry

Author

Spyridon Kostantinis, Bahadir Simsek, Judit Karacsonyi, Khaldoon Alaswad, Michael Megaly, Oleg Krestyaninov, Dmitrii Khelimskii, Farouc Jaffer, Jaikirshan Khatri, Paul Poommipanit, Mitul Patel, Ehtisham Mahmud, Michail Koutouzis, Ioannis Tsiafoutis, Sevket Gorgulu, Basem Elbarouni, William Nicholson, Wissam Jaber, Stephane Rinfret, Omer Goktekin, Ahmed ElGuindy, Yader Sandoval, M. Nicholas Burke, Salman Allana, Bavana Rangan, and Emmanouil Brilakis

Subjects
Cardiology and Cardiovascular Medicine
Published
2022
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24. TCT-128 Saphenous Vein Graft Occlusion Following Native Vessel Chronic Total Occlusion Percutaneous Coronary Intervention

Author

Spyridon Kostantinis, Bahadir Simsek, Judit Karacsonyi, Khaldoon Alaswad, Michael Megaly, Farouc Jaffer, Jaikirshan Khatri, Paul Poommipanit, Rhian Davies, Stephane Rinfret, Basem Elbarouni, Luiz Ybarra, Abdul Sheikh, Catalin Toma, Raj Chandwaney, Omer Goktekin, Ahmed ElGuindy, Olga Mastrodemos, Bavana Rangan, M. Nicholas Burke, and Emmanouil Brilakis

Subjects
Cardiology and Cardiovascular Medicine
Published
2022
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25. TCT-112 Predicting In-Hospital Acute Myocardial Infarction in Chronic Total Occlusion Percutaneous Coronary Intervention: The PROGRESS-CTO Acute Myocardial Infarction Score

Author

Bahadir Simsek, Spyridon Kostantinis, Judit Karacsonyi, Khaldoon Alaswad, Oleg Krestyaninov, Dmitrii Khelimskii, Rhian Davies, Jeremy Rier, Omer Goktekin, Sevket Gorgulu, Ahmed ElGuindy, Raj Chandwaney, Mitul Patel, Dimitri Karmpaliotis, Jaikirshan Khatri, Farouc Jaffer, Paul Poommipanit, Bavana Rangan, Yader Sandoval, Basem Elbarouni, William Nicholson, Stephane Rinfret, Michail Koutouzis, Ioannis Tsiafoutis, Robert Yeh, M. Nicholas Burke, Salman Allana, Olga Mastrodemos, and Emmanouil Brilakis

Subjects
Cardiology and Cardiovascular Medicine
Published
2022
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26. TCT-171 Predicting the Risk of Perforation Requiring Pericardiocentesis in Chronic Total Occlusion Percutaneous Coronary Intervention: The PROGRESS-CTO Pericardiocentesis Score

Author

Bahadir Simsek, Spyridon Kostantinis, Judit Karacsonyi, Khaldoon Alaswad, Oleg Krestyaninov, Dmitrii Khelimskii, Rhian Davies, Jeremy Rier, Omer Goktekin, Sevket Gorgulu, Ahmed ElGuindy, Raj Chandwaney, Mitul Patel, Dimitri Karmpaliotis, Jaikirshan Khatri, Farouc Jaffer, Paul Poommipanit, Bavana Rangan, Yader Sandoval, Basem Elbarouni, William Nicholson, Stephane Rinfret, Michail Koutouzis, Ioannis Tsiafoutis, Robert Yeh, M. Nicholas Burke, Salman Allana, Olga Mastrodemos, and Emmanouil Brilakis

Subjects
Cardiology and Cardiovascular Medicine
Published
2022
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27. TCT-113 Predicting the Risk of In-Hospital Major Adverse Cardiovascular Events in Chronic Total Occlusion Percutaneous Coronary Intervention: The PROGRESS-CTO MACE Score

Author

Bahadir Simsek, Spyridon Kostantinis, Judit Karacsonyi, Khaldoon Alaswad, Oleg Krestyaninov, Dmitrii Khelimskii, Rhian Davies, Jeremy Rier, Omer Goktekin, Sevket Gorgulu, Ahmed ElGuindy, Raj Chandwaney, Mitul Patel, Dimitri Karmpaliotis, Jaikirshan Khatri, Farouc Jaffer, Paul Poommipanit, Bavana Rangan, Yader Sandoval, Basem Elbarouni, William Nicholson, Stephane Rinfret, Michail Koutouzis, Ioannis Tsiafoutis, Robert Yeh, M. Nicholas Burke, Salman Allana, and Emmanouil Brilakis

Subjects
Cardiology and Cardiovascular Medicine
Published
2022
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28. TCT-110 Use of Atherectomy in Chronic Total Occlusion Percutaneous Coronary Intervention

Author

Judit Karacsonyi, Bahadir Simsek, Spyridon Kostantinis, Khaldoon Alaswad, Oleg Krestyaninov, Dimitri Karmpaliotis, Ajay Kirtane, Margaret McEntegart, Jaikirshan Khatri, Paul Poommipanit, Farouc Jaffer, James Choi, Ehtisham Mahmud, Mitul Patel, Michalis Koutouzis, Ioannis Tsiafoutis, Basem Elbarouni, Wissam Jaber, Stephane Rinfret, Brian Jefferson, Taral Patel, Sevket Gorgulu, Ahmed ElGuindy, Nidal Abi-Rafeh, Omer Goktekin, Imre Ungi, Bavana Rangan, Olga Mastrodemos, Yader Sandoval, Salman Allana, M. Nicholas Burke, and Emmanouil Brilakis

Subjects
Cardiology and Cardiovascular Medicine
Published
2022
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29. TCT-319 Use of Limited Antegrade Subintimal Tracking Technique in Chronic Total Occlusion Percutaneous Coronary Intervention

Author

Ioannis Tsiafoutis, Judit Karacsonyi, Farouc A. Jaffer, Robert Riley, Omer Goktekin, Imre Ungi, Vennela Avula, Bahadir Simsek, Dimitri Karmpaliotis, Alessandra Gutierrez, Spyridon Kostantinis, Ahmed ElGuindy, Basem Elbarouni, Paul Poommipanit, Sevket Gorgulu, Nidal Abi-Rafeh, David E. Kandzari, Khaldoon Alaswad, James W. Choi, Emmanouil S. Brilakis, and Jaikirshan Khatri

Subjects
medicine.medical_specialty, business.industry, Internal medicine, medicine.medical_treatment, medicine, Cardiology, Percutaneous coronary intervention, Cardiology and Cardiovascular Medicine, business, Total occlusion
Published
2021
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30. TCT-72 Primary Versus Secondary Retrograde Approach in Chronic Total Occlusion Interventions

Author

William J. Nicholson, Emmanouil S. Brilakis, Wissam Jaber, Stéphane Rinfret, Alessandra Gutierrez, Vennela Avula, Mitul Patel, Jaikirshan Khatri, Sevket Gorgulu, Khaldoon Alaswad, Farouc A. Jaffer, Santiago Garcia, M. Nicholas Burke, Dimitri Karmpaliotis, Spyridon Kostantinis, Omer Goktekin, Evangelia Vemmou, Paul Poommipanit, Abdul M. Sheikh, Bavana V. Rangan, Nidal Abi-Rafeh, Robert Riley, Ilias Nikolakopoulos, Ioannis Tsiafoutis, Judit Karacsonyi, and Ahmed ElGuindy

Subjects
medicine.medical_specialty, business.industry, Psychological intervention, Retrograde approach, Medicine, Cardiology and Cardiovascular Medicine, business, Total occlusion, Surgery
Published
2021
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31. E-30 | Meta-Analysis of Successful vs. Failed Chronic Total Occlusion Percutaneous Coronary Intervention

Author

Bahadir Simsek, Spyridon Kostantinis, Judit Karacsonyi, Khaldoon Alaswad, Dimitrios Karmpaliotis, Wissam A. Jaber, William J. Nicholson, Stéphane Rinfret, Kambis Mashayekhi, Gerald S. Werner, Margaret McEntegart, Seung W. Lee, Bo Xu, Jaikirshan Khatri, Scott A. Harding, Alexandre Avran, Farouc A. Jaffer, Darshan Doshi, Hsien-Li Kao, George Sianos, Masahisa Yamane, Anastasios Milkas, Lorenzo Azzalini, Roberto Garbo, Khalid Omar Tammam, Nidal Abi Rafeh, Ilias Nikolakopoulos, Evangelia Vemmou, Olga C. Mastrodemos, Bavana V. Rangan, M. Nicholas Burke, Santiago Garcia, Kevin J. Croce, Eugene B. Wu, Etsuo Tsuchikane, Carlo Di Mario, Alfredo R. Galassi Prof, Andrea Gagnor, Paul Knaapen, Yangsoo Jang, Byeong-Keuk Kim, Paul Poommipanit, and Emmanouil S. Brilakis

Published
2022
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32. E-15 | Gender Differences in Chronic Total Occlusion Percutaneous Coronary Interventions: Insights from the PROGRESS-CTO Registry

Author

Spyridon Kostantinis, Megha Prasad, Bahadir Simsek, Judit Karacsonyi, Khaldoon Alaswad, Mir B. Basir, Michael S. Megaly, Şevket Görgülü, Oleg Krestyaninov, Dmitrii Khelimskii, Stewart M. Benton, Rhian E. Davies, Jaikirshan Khatri, Farouc A. Jaffer, Paul Poommipanit, Brian Jefferson, Taral N. Patel, Philip Dattilo, M. Nicholas Burke, Santiago Garcia, Michail Koutouzis, Ioannis Tsiafoutis, Ahmed Elguindy, Ömer Göktekin, Nidal Abi Rafeh, Olga C. Mastrodemos, Bavana V. Rangan, and Emmanouil S. Brilakis

Published
2022
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33. E-18 | Intravascular Lithotripsy in Chronic Total Occlusion Percutaneous Coronary Intervention

Author

Spyridon Kostantinis, Bahadir Simsek, Judit Karacsonyi, Khaldoon Alaswad, Mir B. Basir, Michael S. Megaly, Jaikirshan Khatri, Laura Young, Stewart M. Benton, Rhian E. Davies, Paul Poommipanit, Wissam A. Jaber, Philip Dattilo, Nidal Abi Rafeh, Ahmed Elguindy, Ömer Göktekin, Daniel Schimmel, Abdul M. Sheikh, Evangelia Vemmou, Ilias Nikolakopoulos, Olga C. Mastrodemos, Bavana V. Rangan, and Emmanouil S. Brilakis

Published
2022
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34. E-29 | Association of Body Mass Index with Chronic Total Occlusion Percutaneous Coronary Intervention Outcomes: Insights from the Prospective Global Registry for the Study of Chronic Total Occlusion Interventions (PROGRESS-CTO)

Author

Bahadir Simsek, Spyridon Kostantinis, Judit Karacsonyi, Khaldoon Alaswad, Dimitrios Karmpaliotis, Amirali Masoumi, Farouc A. Jaffer, Darshan Doshi, Jaikirshan Khatri, Paul Poommipanit, Şevket Görgülü, Ömer Göktekin, Oleg Krestyaninov, Rhian E. Davies, Lorenzo Azzalini, Ahmed Elguindy, Brian Jefferson, Taral N. Patel, Mitul P. Patel, Raj H. Chandwaney, Olga C. Mastrodemos, Bavana V. Rangan, and Emmanouil S. Brilakis

Published
2022
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35. LB-4 | Contemporary In-Hospital Outcomes and Temporal Trends of Chronic Total Occlusion Percutaneous Coronary Interventions: Insights from the PROGRESS-CTO International Registry

Author

Spyridon Kostantinis, Bahadir Simsek, Judit Karacsonyi, Khaldoon Alaswad, Oleg Krestyaninov, Dmitrii Khelimskii, Dimitrios Karmpaliotis, Farouc A. Jaffer, Jaikirshan Khatri, Paul Poommipanit, James W. Choi, Wissam A. Jaber, Stéphane Rinfret, William J. Nicholson, Mitul P. Patel, Ehtisham Mahmud, Philip Dattilo, Şevket Görgülü, Michail Koutouzis, Ioannis Tsiafoutis, Basem Elbarouni, Abdul M. Sheikh, Barry F. Uretsky, Ahmed Elguindy, Brian Jefferson, Taral Patel, Jason R. Wollmuth, Robert F. Riley, Stewart M. Benton, Rhian E. Davies, Raj H. Chandwaney, Catalin Toma, Robert W. Yeh, Daniel Schimmel, Nidal Abi Rafeh, Ömer Göktekin, Jimmy Lee Kerrigan, M. Nicholas Burke, Olga C. Mastrodemos, Bavana V. Rangan, and Emmanouil S. Brilakis

Published
2022
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36. E-27 | Characteristics and Procedural Outcomes of Balloon Undilatable Lesions in Chronic Total Occlusion Percutaneous Coronary Intervention

Author

Bahadir Simsek, Spyridon Kostantinis, Judit Karacsonyi, Khaldoon Alaswad, Dimitrios Karmpaliotis, Amirali Masoumi, Farouc A. Jaffer, Darshan Doshi, Jaikirshan Khatri, Paul Poommipanit, Şevket Görgülü, Ömer Göktekin, Oleg Krestyaninov, Rhian E. Davies, Ahmed Elguindy, Brian Jefferson, Taral N. Patel, Mitul P. Patel, Raj H. Chandwaney, Bavana V. Rangan, Olga C. Mastrodemos, and Emmanouil S. Brilakis

Published
2022
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37. E-17 | Contemporary In-Hospital Outcomes of Chronic Total Occlusion Interventions: Update from the PROGRESS-CTO (PROspective Global REgiStry for the Study of Chronic Total Occlusion Intervention) International Registry

Author

Spyridon Kostantinis, Bahadir Simsek, Judit Karacsonyi, Khaldoon Alaswad, Mir B. Basir, Michael S. Megaly, Oleg Krestyaninov, Dmitrii Khelimskii, Dimitrios Karmpaliotis, Farouc A. Jaffer, Jaikirshan Khatri, Paul Poommipanit, Mitul P. Patel, Ehtisham Mahmud, Michail Koutouzis, Ioannis Tsiafoutis, James W. Choi, Philip Dattilo, Şevket Görgülü, Basem Elbarouni, William J. Nicholson, Wissam A. Jaber, Stéphane Rinfret, Nidal Abi Rafeh, Ömer Göktekin, Ahmed Elguindy, Olga C. Mastrodemos, Bavana V. Rangan, and Emmanouil S. Brilakis

Published
2022
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38. Sensitivity of Transcranial Doppler Versus Intracardiac Echocardiography in the Detection of Right-to-Left Shunt

Author

Jonathan M. Tobis, Hohai Van, Chi-Hong Tseng, Paul Poommipanit, Rubine Gevorgyan, and Mostafa Helmy Shalaby

Subjects
Adult, Male, Cardiac Catheterization, medicine.medical_specialty, Time Factors, Manometry, Septal Occluder Device, Ultrasonography, Doppler, Transcranial, Valsalva Maneuver, patent foramen ovale, Right-to-left shunt, medicine.medical_treatment, Foramen Ovale, Patent, Atrial Function, Right, Sodium Chloride, transcranial Doppler, Intracardiac injection, Predictive Value of Tests, Coronary Circulation, Internal medicine, medicine.artery, Pressure, medicine, Valsalva maneuver, Humans, Radiology, Nuclear Medicine and imaging, Stroke, Aged, Foramen ovale (heart), Cardiac catheterization, business.industry, Middle Aged, medicine.disease, Transcranial Doppler, Treatment Outcome, medicine.anatomical_structure, Ischemic Attack, Transient, Radiology Nuclear Medicine and imaging, Cerebrovascular Circulation, cardiovascular system, Cardiology, Patent foramen ovale, Female, Cardiology and Cardiovascular Medicine, business, Echocardiography, Transesophageal
Abstract

OBJECTIVES: The purpose of this study was to understand the reason for variation in the sensitivity of different methods of detecting right-to-left shunts (RLS). BACKGROUND: Patent foramen ovale (PFO) is implicated in the pathogenesis of cryptogenic stroke, decompression illness, and migraine headaches. Intravenous agitated saline injections with tomographic imaging (transthoracic, transesophageal, and intracardiac echocardiography) has been used for detecting intracardiac shunts. Some patients with a high clinical suspicion of PFO have inconclusive echocardiographic study results. Transcranial Doppler (TCD) is an alternative method for detecting RLS that is not dependent on tomographic imaging. METHODS: Thirty-eight consecutive patients who were undergoing PFO closure had simultaneous transcranial Doppler and intracardiac echocardiography performed. Agitated saline injections were performed at rest, with Valsalva maneuver, and with forced expiration into a manometer to 40 mm Hg before and after closure, as well as 3 or more months after closure. Right atrial pressures were measured in the periprocedural period, and RLS were graded according to standard methods during these maneuvers. RESULTS: Right atrial pressures were significantly higher with Valsalva maneuver compared with rest (before closure 21.6 +/- 11.9 mm Hg vs. 6.6 +/- 2.6 mm Hg, p < 0.001; after closure 28.4 +/- 13.9 mm Hg vs. 6.8 +/- 2.6 mm Hg, p < 0.001) and with manometer compared with Valsalva maneuver (before closure 38.7 +/- 6.6 mm Hg vs. 21.6 +/- 11.9 mm Hg, p < 0.001; after closure 44.0 +/- 9.5 mm Hg vs. 28.4 +/- 13.9 mm Hg, p < 0.001). Intracardiac echocardiography underestimated shunting in 34% of patients with Valsalva maneuver or manometer after closure compared with TCD. CONCLUSIONS: Transcranial Doppler with immediate feedback provided by forced expiration against a manometer to 40 mm Hg is more sensitive than echocardiographic imaging for the detection of RLS. These observations have significant implications for determining the incidence of RLS in patients with stroke or migraine.

Published
2010
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